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glioblastoma (3) 3
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1. Full Text Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial
by Weller, Michael and Butowski, Nicholas and Tran, David D and Recht, Lawrence and Recht, Lawrence D and Lim, Michael and Hirte, Hal and Ashby, Lynn and Mechtler, Laszlo and Goldlust, Samuel and Goldlust, Samuel A and Iwamoto, Fabio and Drappatz, Jan and O'Rourke, James and O'Rourke, Donald M and Wong, Mark and Hamilton, Mark G and Hamilton, Mark and Finocchiaro, Gaetano and Perry, James and Wick, Wolfgang and Green, Jennifer and He, Yi and Turner, Christopher D and Yellin, Michael J and Keler, Tibor and Davis, Thomas A and Stupp, Roger and Sampson, John H and Campian, Jian and Becker, Kevin and Barnett, Gene and Nicholas, Garth and Desjardins, Annick and Benkers, Tara and Wagle, Naveed and Groves, Morris and Kesari, Santosh and Horvath, Zsolt and Merrell, Ryan and Curry, Richard and Schuster, David and Mrugala, Maciej and Jensen, Randy and Trusheim, John and Lesser, Glenn and Belanger, Karl and Sloan, Andrew and Purow, Benjamin and Fink, Karen and Raizer, Jeffrey and Schulder, Michael and Nair, Suresh and Peak, Scott and Brandes, Alba and Mohile, Nimish and Landolfi, Joseph and Olson, Jon and Jennens, Ross and DeSouza, Paul and Robinson, Bridget and Crittenden, Marka and Shih, Kent and Flowers, Alexandra and Ong, Shirley and Connelly, Jennifer and Hadjipanayis, Costas and Giglio, Pierre and Mott, Frank and Mathieu, David and Lessard, Nathalie and Sepulveda, Sanchez Juan and Lövey, József and Wheeler, Helen and Inglis, Po-Ling and Hardie, Claire and Bota, Daniela and Lesniak, Maciej and Portnow, Jana and Frankel, Bruce and Junck, Larry and Thompson, Reid and Berk, Lawrence and McGhie, John and Macdonald, David and Saran, Frank and Soffietti, Riccardo and Blumenthal, Deborah and André de, Sá Barreto Costa Marcos and Nowak, Anna and Singhal, Nimit and Hottinger, Andreas and Schmid, Andrea and Srkalovic, Gordan and Baskin, David and Fadul, Camilo and Nabors, Louis and LaRocca, Renato and Villano, John and Paleologos, Nina and ... and ACT IV Trial Investigators and ACT IV trial investigators
The Lancet Oncology, ISSN 1470-2045, 10/2017, Volume 18, Issue 10, pp. 1373 - 1385
Rindopepimut (also known as CDX-110), a vaccine targeting the deletion mutation EGFRvIII, consists of an EGFRvIII-specific peptide conjugated to keyhole limpet... 
GLIOMAS | ONCOLOGY | RECURSIVE PARTITIONING ANALYSIS | GROWTH-FACTOR | RADIOTHERAPY | CANCER | PEPTIDE | ADJUVANT TEMOZOLOMIDE | Dacarbazine - adverse effects | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Follow-Up Studies | Humans | Middle Aged | Brain Neoplasms - pathology | ErbB Receptors - genetics | Gene Expression Regulation, Neoplastic | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Patient Selection | Dose-Response Relationship, Drug | Young Adult | Glioblastoma - genetics | Time Factors | Dacarbazine - analogs & derivatives | Adult | Female | Vaccines, Subunit - adverse effects | Brain Neoplasms - mortality | Dacarbazine - administration & dosage | Double-Blind Method | Drug Administration Schedule | Cancer Vaccines - administration & dosage | Kaplan-Meier Estimate | Proportional Hazards Models | Brain Neoplasms - genetics | Cancer Vaccines - adverse effects | Treatment Outcome | Brain Neoplasms - drug therapy | Disease-Free Survival | Internationality | Vaccines, Subunit - administration & dosage | Glioblastoma - pathology | Survival Analysis | Aged | Temozolomide | Glioblastoma - drug therapy | Glioblastoma - mortality | Antimitotic agents | Clinical trials | Care and treatment | Product development | Antineoplastic agents | Glioblastoma multiforme | Analysis
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2. Full Text The dystroglycan receptor maintains glioma stem cells in the vascular niche
by Day, Bryan W and Lathia, Justin D and Bruce, Zara C and D’Souza, Rochelle C. J and Baumgartner, Ulrich and Ensbey, Kathleen S and Lim, Yi Chieh and Stringer, Brett W and Akgül, Seçkin and Offenhäuser, Carolin and Li, Yuchen and Jamieson, Paul R and Smith, Fiona M and Jurd, Courtney L. R and Robertson, Thomas and Inglis, Po-Ling and Lwin, Zarnie and Jeffree, Rosalind L and Johns, Terrance G and Bhat, Krishna P. L and Rich, Jeremy N and Campbell, Kevin P and Boyd, Andrew W
Acta Neuropathologica, ISSN 0001-6322, 12/2019, Volume 138, Issue 6, pp. 1033 - 1052
Glioblastomas (GBMs) are malignant central nervous system (CNS) neoplasms with a very poor prognosis. They display cellular hierarchies containing... 
Pathology | Neurosciences | Glioma stem cell (GSC) commitment | Medicine & Public Health | Glioblastoma (GBM) | MES-like GBM | Dystroglycan (DG) | Perivascular niche | MAPK signalling | EphA3 | Integrin-α6 | Dystroglycan | Mesenchyme | Glioma cells | Central nervous system | Stem cells | Extracellular signal-regulated kinase | Extracellular matrix | MAP kinase | Tumors | Original Paper
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3. Full Text A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma
by Stringer, Brett W and Day, Bryan W and D’Souza, Rochelle C. J and Jamieson, Paul R and Ensbey, Kathleen S and Bruce, Zara C and Lim, Yi Chieh and Goasdoué, Kate and Offenhäuser, Carolin and Akgül, Seçkin and Allan, Suzanne and Robertson, Thomas and Lucas, Peter and Tollesson, Gert and Campbell, Scott and Winter, Craig and Do, Hongdo and Dobrovic, Alexander and Inglis, Po-Ling and Jeffree, Rosalind L and Johns, Terrance G and Boyd, Andrew W
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 4902 - 14
Low-passage, serum-free cell lines cultured from patient tumour tissue are the gold-standard for preclinical studies and cellular investigations of... 
HETEROGENEITY | STEM-CELLS | PHOSPHORYLATION | SUBTYPES | MULTIDISCIPLINARY SCIENCES | INHIBITORS | TUMORIGENICITY | EXPRESSION | RADIATION | CULTURE | TEMOZOLOMIDE | Gold | CRISPR | Cell culture | Mesenchyme | Plasmids | Glioblastoma | Cell lines | Xenografts | Labelling | Tumor cell lines | Gene expression | Tumors
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4. Full Text Lean thinking: Exploring the volume of overhead and supplementary tasks (OST) in cancer care (CC) in the oncology outpatient encounter (OOE) in two tertiary centres
by Peters, Geoffrey David and Rasool, Madiha and Smith, David D and Ladwa, Rahul and Wyld, David and Eastgate, Melissa A and Xu, Wen and Kalokerinos, Paul Nicholas and Tan, Joanne Yue-Ai and Goh, Jeffrey C and Nottage, Michelle K and Inglis, Po-Ling and Burge, Matthew E and Al-Saig, Haider and Hughes, Brett Gordon Maxwell and Lwin, Zarnie
Journal of Clinical Oncology, ISSN 0732-183X, 05/2016, Volume 34, Issue 15_suppl, pp. 6589 - 6589
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