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Molecules, ISSN 1420-3049, 2018, Volume 23, Issue 5, p. 1209
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 03/2019, Volume 165, pp. 250 - 257
Sigma receptors (σRs) are considered to be a significant and valid target for developing new medications to address several diseases. Their potential... 
Sigma-2 ligands | Sigma receptors | Cocaine-induced convulsions | Cocaine's toxicity | Structure-affinity relationships | Sigma-2 receptors | Benzimidazolone | Index Medicus
Journal Article
The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 02/2019, Volume 368, Issue 2, pp. 272 - 281
Sigma-2 receptors, recently identified as TMEM97, have been implicated in cancer and neurodegenerative disease. Structurally distinct sigma-2 receptor ligands... 
Journal Article
FRONTIERS IN PHARMACOLOGY, ISSN 1663-9812, 06/2019, Volume 10, pp. 678 - 678
Sigma-1 receptors (SIR) and sigma-2 receptors (S2R) may modulate nociception without the liabilities of opioids, offering a promising therapeutic target to... 
MECHANICAL ALLODYNIA | chronic pain | ANESTHETIC POTENCY | CONDITIONED PLACE PREFERENCE | Sigma | analgesia | addiction | SPINAL-CORD | S1RA | TANDEM MASS-SPECTROMETRY | ANTINOCICEPTION | sedation | NEUROPATHIC PAIN | allodynia | NMDA-INDUCED PAIN | PHARMACOLOGY & PHARMACY | NR1 SUBUNIT | Care and treatment | Pain
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 10/2018, Volume 61, Issue 19, pp. 8475 - 8503
Serotonin 5-HT7 receptor (5-HT7R) has been the subject of intense research efforts because of its presence in brain areas such as the hippocampus,... 
SEROTONIN RECEPTOR | ACID AMIDE FRAGMENTS | CHEMISTRY, MEDICINAL | SOLID-SUPPORTED SYNTHESIS | ANIMAL-MODELS | ARYLSULFONAMIDE DERIVATIVES | ANTIDEPRESSANT-LIKE BEHAVIOR | EYE-MOVEMENT SLEEP | IN-VIVO EVALUATION | MULTIOBJECTIVE BASED DESIGN | SPLICE VARIANTS
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 07/2019, Volume 174, pp. 226 - 235
A new set of 5-chlorobenzoxazole- and 5-chlorobenzothiazole-based derivatives containing the azepane ring as a basic moiety was designed, synthesized and... 
Pain | Sigma-1 receptors | Benzothiazole | Benzoxazole | Sigma-2 receptors | Cancer | Apoptosis | CHEMISTRY, MEDICINAL | ANTAGONIST | HIGH-AFFINITY | MODEL | IDENTIFICATION | SELECTIVE LIGANDS | POTENT | 5-HT1A | DERIVATIVES | BINDING | SCAFFOLD | Index Medicus
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2018, Volume 158, pp. 937 - 950
Journal Article
Journal of medicinal chemistry, 10/2018, Volume 61, Issue 19, p. 8475
Serotonin 5-HT receptor (5-HT R) has been the subject of intense research efforts because of its presence in brain areas such as the hippocampus, hypothalamus,... 
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2014, Volume 85, pp. 716 - 726
A novel series of arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones – was designed, synthesized and tested to evaluate their affinity for the 5-HT... 
5-HT1A | Ligands | Receptors | 5-HT7 | Serotonin | LCAP | SEROTONIN RECEPTOR | CHEMISTRY, MEDICINAL | HIGH-AFFINITY | CNS | POTENT | LURASIDONE | CLONING | AGENTS | ANTAGONISTS | DERIVATIVES | SELECTIVITY
Journal Article
Future medicinal chemistry, 07/2019, Volume 11, Issue 13, p. 1523
Dimethyl fumarate (DMF) analogs were synthesized to obtain inducers of HO-1 and antifibrotic agents. HO-1 expression levels were measured on lung fibroblasts... 
Journal Article
The Journal of pharmacology and experimental therapeutics, 12/2018
Sigma-2 receptors, recently identified as TMEM97, have been implicated in cancer and neurodegenerative disease. Structurally distinct sigma-2 receptor ligands... 
Journal Article
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