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index medicus (6) 6
cardiac & cardiovascular systems (5) 5
cardiovascular (4) 4
heart failure (4) 4
humans (4) 4
male (4) 4
aged (3) 3
analysis (3) 3
cardiology (3) 3
female (3) 3
heart diseases (3) 3
mortality (3) 3
patients (3) 3
registries (3) 3
time factors (3) 3
abridged index medicus (2) 2
aged, 80 and over (2) 2
animals (2) 2
aortic valve stenosis - therapy (2) 2
cardiology and cardiovascular medicine (2) 2
clinical outcomes (2) 2
echocardiography (2) 2
end-point definitions (2) 2
epidemiology (2) 2
follow-up studies (2) 2
guidelines (2) 2
heart (2) 2
heart attacks (2) 2
impact (2) 2
internal medicine (2) 2
medical colleges (2) 2
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myocardium - pathology (2) 2
outcomes (2) 2
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severity of illness index (2) 2
society (2) 2
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treatment outcome (2) 2
acute coronary syndromes (1) 1
acute disease (1) 1
adhere (1) 1
adults (1) 1
aging (1) 1
aging - pathology (1) 1
aging - physiology (1) 1
amino acids (1) 1
amphotericin-b (1) 1
anemia (1) 1
animal models (1) 1
antifungal agents (1) 1
aortic stenosis (1) 1
aortic valve replacement (1) 1
aortic valve stenosis (1) 1
aortic valve stenosis - complications (1) 1
aortic valve stenosis - diagnosis (1) 1
aortic valve stenosis - diagnostic imaging (1) 1
aortic valve stenosis - mortality (1) 1
association (1) 1
autophagy - physiology (1) 1
b-type natriuretic peptide (1) 1
biochemistry (1) 1
biology (1) 1
biomarkers (1) 1
blood pressure (1) 1
body temperature (1) 1
caloric restriction (1) 1
carbohydrate metabolism (1) 1
cardiac arrhythmia (1) 1
cardiac patients (1) 1
cardiac-hypertrophy (1) 1
cardiotonic agents - pharmacology (1) 1
cardiovascular agents (1) 1
cardiovascular agents - adverse effects (1) 1
cardiovascular agents - therapeutic use (1) 1
care and treatment (1) 1
case reports (1) 1
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diagnostic medicine (1) 1
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disease (1) 1
diuretics (1) 1
diuretics - administration & dosage (1) 1
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1. Full Text Initial Surgical Versus Conservative Strategies in Patients With Asymptomatic Severe Aortic Stenosis
by Taniguchi, Tomohiko, MD and Morimoto, Takeshi, MD, MPH and Shiomi, Hiroki, MD and Ando, Kenji, MD and Kanamori, Norio, MD and Murata, Koichiro, MD and Kitai, Takeshi, MD and Kawase, Yuichi, MD and Izumi, Chisato, MD and Miyake, Makoto, MD and Mitsuoka, Hirokazu, MD and Kato, Masashi, MD and Hirano, Yutaka, MD and Matsuda, Shintaro, MD and Nagao, Kazuya, MD and Inada, Tsukasa, MD and Murakami, Tomoyuki, MD and Takeuchi, Yasuyo, MD and Yamane, Keiichiro, MD and Toyofuku, Mamoru, MD and Ishii, Mitsuru, MD and Minamino-Muta, Eri, MD and Kato, Takao, MD and Inoko, Moriaki, MD and Ikeda, Tomoyuki, MD and Komasa, Akihiro, MD and Ishii, Katsuhisa, MD and Hotta, Kozo, MD and Higashitani, Nobuya, MD and Kato, Yoshihiro, MD and Inuzuka, Yasutaka, MD and Maeda, Chiyo, MD and Jinnai, Toshikazu, MD and Morikami, Yuko, MD and Sakata, Ryuzo, MD and Kimura, Takeshi, MD and CURRENT AS Registry Investigators
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2015, Volume 66, Issue 25, pp. 2827 - 2838
Abstract Background Current guidelines generally recommend watchful waiting until symptoms emerge for aortic valve replacement (AVR) in asymptomatic patients... 
Cardiovascular | Internal Medicine | registry | risk | aortic valve replacement | propensity-matched | watchful waiting | SURVIVAL | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | ADULTS | NATURAL-HISTORY | SOCIETY | END-POINT DEFINITIONS | TRANSCATHETER | IMPLANTATION | PREDICTORS | VALVE-REPLACEMENT | Severity of Illness Index | Echocardiography | Heart Valve Prosthesis Implantation - standards | Follow-Up Studies | Humans | Risk Factors | Male | Treatment Outcome | Aortic Valve Stenosis - diagnosis | Aortic Valve Stenosis - therapy | Propensity Score | Time Factors | Aged, 80 and over | Female | Registries | Aged | Watchful Waiting - standards | Practice Guidelines as Topic | Medical colleges | Care and treatment | Aortic valve stenosis | Cardiovascular agents | College teachers | Cardiology | Epidemiology | Analysis | Hospitalization | Heart attacks | Mortality | Clinical outcomes
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2. Full Text Time-to-Furosemide Treatment and Mortality in Patients Hospitalized With Acute Heart Failure
by Matsue, Yuya, MD, PhD and Damman, Kevin, MD, PhD and Voors, Adriaan A., MD, PhD and Kagiyama, Nobuyuki, MD and Yamaguchi, Tetsuo, MD, PhD and Kuroda, Shunsuke, MD and Okumura, Takahiro, MD, PhD and Kida, Keisuke, MD, PhD and Mizuno, Atsushi, MD and Oishi, Shogo, MD and Inuzuka, Yasutaka, MD, PhD and Akiyama, Eiichi, MD and Matsukawa, Ryuichi, MD, PhD and Kato, Kota, MD, PhD and Suzuki, Satoshi, MD, PhD and Naruke, Takashi, MD, PhD and Yoshioka, Kenji, MD and Miyoshi, Tatsuya, MD, PhD and Baba, Yuichi, MD and Yamamoto, Masayoshi, MD, PhD and Murai, Koji, MD and Mizutani, Kazuo, MD, PhD and Yoshida, Kazuki, MD, MPH, MS and Kitai, Takeshi, MD, PhD
Journal of the American College of Cardiology, ISSN 0735-1097, 06/2017, Volume 69, Issue 25, pp. 3042 - 3051
Abstract Background Acute heart failure (AHF) is a life-threatening disease requiring urgent treatment, including a recommendation for immediate initiation of... 
Cardiovascular | Internal Medicine | B-type natriuretic peptide | Get With the Guidelines | emergency department | diuretics | prognosis | CARDIOLOGY | GUIDELINES | RISK SCORE | RELAX-AHF | EUROPEAN-SOCIETY | THERAPY | ADHERE | OUTCOMES | ASSOCIATION | PROGRAM | IMPACT | CARDIAC & CARDIOVASCULAR SYSTEMS | DYSPNEA | Furosemide - administration & dosage | Acute Disease | Diuretics - administration & dosage | Injections, Intravenous | Prospective Studies | Survival Rate - trends | Follow-Up Studies | Time-to-Treatment | Humans | Male | Heart Failure - drug therapy | Hospital Mortality - trends | Inpatients | Time Factors | Female | Registries | Aged | Odds Ratio | Heart Failure - mortality | Heart failure | Heart | Medical colleges | Patient outcomes | Cardiac patients | Mortality | Furosemide | Analysis | Intravenous administration | Enrollments | Medical services | Gender differences | Emergency medical care | Congestion | Emergency exits | Multivariate analysis | Patients | Confidence intervals | Studies | Variables | Hospitals | Diuretics | Emergency vehicles | Acute coronary syndromes | Cardiology | Heart diseases | Emergency medical services
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3. Full Text Aging as a substrate of heart failure
by Shioi, Tetsuo, MD, PhD and Inuzuka, Yasutaka, MD, PhD
Journal of Cardiology, ISSN 0914-5087, 2012, Volume 60, Issue 6, pp. 423 - 428
Abstract Heart failure is a typical age-associated disease. However, the mechanism by which heart function declines and heart failure increases in association... 
Cardiovascular | Heart failure | Aging | Rapamycin | Protein homeostasis | Insulin | LIFE-SPAN | CARDIAC & CARDIOVASCULAR SYSTEMS | MITOCHONDRIA | DIASTOLIC DYSFUNCTION | LONGEVITY | OVEREXPRESSION | CARDIAC-HYPERTROPHY | CALORIC RESTRICTION | DISEASE | SENESCENCE | MICE | Insulin - physiology | Humans | Oxidative Stress - physiology | Homeostasis | Myocardium - pathology | Autophagy - physiology | Inflammation - etiology | Proteasome Endopeptidase Complex - physiology | Ubiquitin - physiology | Aging - pathology | Animals | Proteins - metabolism | Aging - physiology | Insulin-Like Growth Factor I - physiology | Myocardium - metabolism | Signal Transduction - physiology | Telomere - physiology | DNA Damage | Heart Failure - etiology
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4. Full Text Combined Surgical and Medical Therapy for Candida Prosthetic Endocarditis in a Patient with Repaired Tetralogy of Fallot
by Kubota, Kana and Soma, Katsura and Uehara, Masae and Inaba, Toshiro and Saito, Akihito and Takeda, Norihiko and Hatano, Masaru and Morita, Hiroyuki and Inuzuka, Ryo and Hirata, Yasutaka and Yao, Atsushi and Komuro, Issei
International Heart Journal, ISSN 1349-2365, 2018, Volume 59, Issue 4, pp. 877 - 880
Candida prosthetic endocarditis (CPE) is an uncommon and fatal complication in adults with congenital heart disease. The current guidelines for the management... 
Case reports | Infective endocarditis | Fluconazole | Pulmonary valve | Antifungal agents | CASPOFUNGIN | CARDIAC & CARDIOVASCULAR SYSTEMS | MANAGEMENT | GUIDELINES | FUNGAL ENDOCARDITIS | AMPHOTERICIN-B | SOCIETY | VALVE ENDOCARDITIS | DOUBLE-BLIND | Fungi | Tetralogy of Fallot | Prostheses | Endocarditis | Electrocardiography | Rheumatic heart disease | Children | Heart diseases | Patients | Coronary artery disease
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5. Full Text Persistent Overexpression of Phosphoglycerate Mutase, a Glycolytic Enzyme, Modifies Energy Metabolism and Reduces Stress Resistance of Heart in Mice
by Okuda, Junji and Niizuma, Shinnichiro and Shioi, Tetsuo and Kato, Takao and Inuzuka, Yasutaka and Kawashima, Tsuneaki and Tamaki, Yodo and Kawamoto, Akira and Tanada, Yohei and Iwanaga, Yoshitaka and Narazaki, Michiko and Matsuda, Tetsuya and Adachi, Souichi and Soga, Tomoyoshi and Takemura, Genzou and Kondoh, Hiroshi and Kita, Toru and Kimura, Takeshi
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e72173
Background: Heart failure is associated with changes in cardiac energy metabolism. Glucose metabolism in particular is thought to be important in the... 
PRESSURE-OVERLOAD | IDIOPATHIC DILATED CARDIOMYOPATHY | COMPLEX-II | MULTIDISCIPLINARY SCIENCES | MYOCARDIAL FATTY-ACID | MITOCHONDRIAL-FUNCTION | PROTEIN EXPRESSION | MECHANISMS | FAILURE | LEFT-VENTRICULAR HYPERTROPHY | RECEPTOR-ALPHA | Phosphoglycerate Mutase - metabolism | Reactive Oxygen Species - metabolism | Male | Glycolysis - genetics | Organ Specificity - genetics | Mitochondria - genetics | Myocardium - metabolism | Energy Metabolism - genetics | Heart - physiopathology | Gene Expression | Echocardiography | Magnetic Resonance Spectroscopy | Stress, Physiological - genetics | Metabolome | Mice, Transgenic | Myocardium - pathology | Mitochondria - metabolism | Cardiotonic Agents - pharmacology | Phosphoglycerate Mutase - genetics | Metabolomics - methods | Dobutamine - pharmacology | Heart - diagnostic imaging | Animals | Fibrosis | Radionuclide Imaging | Glucose - metabolism | Heart - drug effects | Mice | Enzyme Activation | Heart failure | Heart | Enzymes | Amino acids | Glucose | Fatty acids | Dextrose | Glucose metabolism | Metabolites | Analysis | Physiological aspects | Stress management | Stress (Psychology) | Tricarboxylic acid cycle | Systems science | Energy metabolism | Reactive oxygen species | Dehydrogenases | Heart attacks | Pathogenesis | Kinases | Proteins | Mitochondria | Transgenic animals | Phosphoglycerate mutase | Rodents | Blood pressure | Oxidation | Cardiology | Heart diseases | Informatics | Transgenic mice | Phosphocreatine | Metabolism | Gene expression | Medicine | Stem cells | Glycolysis | Diabetes | Lactic acid | Electron transport
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6. Full Text Severe Aortic Stenosis in Dialysis Patients
by Kawase, Yuichi and Taniguchi, Tomohiko and Morimoto, Takeshi and Kadota, Kazushige and Iwasaki, Keiichiro and Kuwayama, Akimune and Ohya, Masanobu and Shimada, Takenobu and Amano, Hidewo and Maruo, Takeshi and Fuku, Yasushi and Izumi, Chisato and Kitai, Takeshi and Saito, Naritatsu and Minamino‐Muta, Eri and Kato, Takao and Inada, Tsukasa and Inoko, Moriaki and Ishii, Katsuhisa and Komiya, Tatsuhiko and Hanyu, Michiya and Minatoya, Kenji and Kimura, Takeshi and CURRENT AS Registry Investigators
Journal of the American Heart Association, ISSN 2047-9980, 07/2017, Volume 6, Issue 7, p. n/a
Background Characteristics and prognosis of hemodialysis patients with severe aortic stenosis have not yet been well defined. Methods and Results The CURRENT... 
hemodialysis | prognosis | aortic stenosis | Aortic stenosis | Hemodialysis | Prognosis | KIDNEY-DISEASE | MORTALITY | SURVIVAL | CARDIAC & CARDIOVASCULAR SYSTEMS | END-POINT DEFINITIONS | REPLACEMENT | IMPACT | VALVE IMPLANTATION | HEMODIALYSIS-PATIENTS | OUTCOMES | PROGRESSION | Humans | Kidney Diseases - diagnosis | Male | Cause of Death | Aortic Valve Stenosis - diagnostic imaging | Aortic Valve Stenosis - mortality | Protective Factors | Renal Dialysis - mortality | Time Factors | Aged, 80 and over | Female | Registries | Kidney Diseases - complications | Retrospective Studies | Severity of Illness Index | Japan | Risk Factors | Heart Valve Prosthesis Implantation - mortality | Kidney Diseases - mortality | Treatment Outcome | Aortic Valve Stenosis - therapy | Cardiovascular Agents - therapeutic use | Aortic Valve Stenosis - complications | Heart Valve Prosthesis Implantation - adverse effects | Renal Dialysis - adverse effects | Kidney Diseases - therapy | Aged | Cardiovascular Agents - adverse effects
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7. Full Text Risk factors and clinical outcomes of functional decline during hospitalisation in very old patients with acute decompensated heart failure: an observational study
by Yaku, Hidenori and Kato, Takao and Morimoto, Takeshi and Inuzuka, Yasutaka and Tamaki, Yodo and Ozasa, Neiko and Yamamoto, Erika and Yoshikawa, Yusuke and Kitai, Takeshi and Kato, Masashi and Ikeda, Tomoyuki and Furukawa, Yutaka and Nakagawa, Yoshihisa and Sato, Yukihito and Kuwahara, Koichiro and Kimura, Takeshi
BMJ Open, ISSN 2044-6055, 2/2020, Volume 10, Issue 2, p. e032674
ObjectiveTo investigate the prevalence and risk factors of functional decline during hospitalisation and its relationship with postdischarge outcomes in very... 
Heart failure | Cardiac arrhythmia | Wheelchairs | Anemia | Body temperature | Patients | Epidemiology | Clinical outcomes
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