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by Gieger, Christian and Radhakrishnan, Aparna and Cvejic, Ana and Tang, Weihong and Porcu, Eleonora and Pistis, Giorgio and Serbanovic-Canic, Jovana and Elling, Ulrich and Goodall, Alison H and Labrune, Yann and Lopez, Lorna M and Mägi, Reedik and Meacham, Stuart and Okada, Yukinori and Pirastu, Nicola and Sorice, Rossella and Teumer, Alexander and Voss, Katrin and Zhang, Weihua and Ramirez-Solis, Ramiro and Bis, Joshua C and Ellinghaus, David and Gögele, Martin and Hottenga, Jouke-Jan and Langenberg, Claudia and Kovacs, Peter and O'Reilly, Paul F and Shin, So-Youn and Esko, Tõnu and Hartiala, Jaana and Kanoni, Stavroula and Murgia, Federico and Parsa, Afshin and Stephens, Jonathan and van der Harst, Pim and van der Schoot, C. Ellen and Allayee, Hooman and Attwood, Antony and Balkau, Beverley and Bastardot, François and Basu, Saonli and Baumeister, Sebastian E and Biino, Ginevra and Bomba, Lorenzo and Bonnefond, Amélie and Cambien, François and Chambers, John C and Cucca, Francesco and D'Adamo, Pio and Davies, Gail and de Boer, Rudolf A and de Geus, Eco J. C and Döring, Angela and Elliott, Paul and Erdmann, Jeanette and Evans, David M and Falchi, Mario and Feng, Wei and Folsom, Aaron R and Frazer, Ian H and Gibson, Quince D and Glazer, Nicole L and Hammond, Chris and Hartikainen, Anna-Liisa and Heckbert, Susan R and Hengstenberg, Christian and Hersch, Micha and Illig, Thomas and Loos, Ruth J. F and Jolley, Jennifer and Khaw, Kay Tee and Kühnel, Brigitte and Kyrtsonis, Marie-Christine and Lagou, Vasiliki and Lloyd-Jones, Heather and Lumley, Thomas and Mangino, Massimo and Maschio, Anea and Mateo Leach, Irene and McKnight, Barbara and Memari, Yasin and Mitchell, Braxton D and Montgomery, Grant W and Nakamura, Yusuke and Nauck, Matthias and Navis, Gerjan and Nöthlings, Ute and Nolte, Ilja M and Porteous, David J and Pouta, Anneli and Pramstaller, Peter P and Pullat, Janne and Ring, Susan M and Rotter, Jerome I and Ruggiero, Daniela and Ruokonen, Aimo and Sala, Cinzia and Samani, Nilesh J and Sambrook, Jennifer and Schlessinger, David and ...
Nature, ISSN 0028-0836, 2011, Volume 480, Issue 7376, pp. 201 - 208
Journal Article
by van der Harst, P and Zhang, W and Mateo Leach, I and Rendon, A and Verweij, N and Sehmi, J and Paul, D.S and Elling, U and Allayee, H and Li, X and Radhakrishnan, A and Tan, S.T and Voss, K and Weichenberger, C.X and Albers, C.A and Al-Hussani, A and Asselbergs, F.W and Ciullo, M and Danjou, F and Dina, C and Esko, T and Evans, D.M and Franke, L and Gogele, M and Hartiala, J and Hersch, M and Holm, H and Hottenga, J.J and Kanoni, S and Kleber, M.E and Lagou, V and Langenberg, C and Lopez, L.M and Lyytikainen, L.P and Melander, O and Murgia, F and Nolte, I.M and O'Reilly, P.F and Padmanabhan, S and Parsa, A and Pirastu, N and Porcu, E and Portas, L and Prokopenko, I and Ried, J.S and Shin, S.Y and Tang, C.S and Teumer, A and Traglia, M and Ulivi, S and Westra, H.J and Yang, J and Zhao, J.H and Anni, F and Abdellaoui, A and Attwood, A and Balkau, B and Bandinelli, S and Bastardot, F and Benyamin, B and Boehm, B.O and Cookson, W.O and Das, D and de Bakker, P.I and de Boer, R.A and de Geus, E.J and de Moor, M.H and Dimitriou, M and Domingues, F.S and Doring, A and Engstrom, G and Eyjolfsson, G.I and Ferrucci, L and Fischer, K and Galanello, R and Garner, S.F and Genser, B and Gibson, Q.D and Girotto, G and Gudbjartsson, D.F and Harris, S.E and Hartikainen, A.L and Hastie, C.E and Hedblad, B and Illig, T and Jolley, J and Kahonen, M and Kema, I.P and Kemp, J.P and Liang, L and Lloyd-Jones, H and Loos, R.J and Meacham, S and Medland, S.E and Meisinger, C and Memari, Y and Mihailov, E and Miller, K and Moffatt, M.F and Nauck, M., et al and Cardiovascular Research - Hypertension and Kardiovaskulär forskning - hypertoni and Kardiovaskulär forskning - epidemiologi and Lund University and EpiHealth: Epidemiology for Health and Cardiovascular Research - Epidemiology and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
Nature, ISSN 0028-0836, 2012, Volume 492, Issue 7429, pp. 369 - 375
Journal Article
by Jacobs, Kevin B and Yeager, Meredith and Zhou, Weiyin and Wacholder, Sholom and Wang, Zhaoming and Rodriguez-Santiago, Benjamin and Hutchinson, Amy and Deng, Xiang and Liu, Chenwei and Horner, Marie-Josephe and Cullen, Michael and Epstein, Caroline G and Burdett, Laurie and Dean, Michael C and Chatterjee, Nilanjan and Sampson, Joshua and Chung, Charles C and Kovaks, Joseph and Gapstur, Susan M and Stevens, Victoria L and Teras, Lauren T and Gaudet, Mia M and Albanes, Demetrius and Weinstein, Stephanie J and Virtamo, Jarmo and Taylor, Philip R and Freedman, Neal D and Abnet, Christian C and Goldstein, Alisa M and Hu, Nan and Yu, Kai and Yuan, Jian-Min and Liao, Linda and Ding, Ti and Qiao, You-Lin and Gao, Yu-Tang and Koh, Woon-Puay and Xiang, Yong-Bing and Tang, Ze-Zhong and Fan, Jin-Hu and Aldrich, Melinda C and Amos, Christopher and Blot, William J and Bock, Cathryn H and Gillanders, Elizabeth M and Harris, Curtis C and Haiman, Christopher A and Henderson, Brian E and Kolonel, Laurence N and Le Marchand, Loic and McNeill, Lorna H and Rybicki, Benjamin A and Schwartz, Ann G and Signorello, Lisa B and Spitz, Margaret R and Wiencke, John K and Wrensch, Margaret and Wu, Xifeng and Zanetti, Krista A and Ziegler, Regina G and Figueroa, Jonine D and Garcia-Closas, Montserrat and Malats, Nuria and Marenne, Gaelle and Prokunina-Olsson, Ludmila and Baris, Dalsu and Schwenn, Molly and Johnson, Alison and Landi, Maria Teresa and Goldin, Lynn and Consonni, Dario and Bertazzi, Pier Alberto and Rotunno, Melissa and Rajaraman, Preetha and Andersson, Ulrika and Freeman, Laura E. Beane and Berg, Christine D and Buring, Julie E and Butler, Mary A and Carreon, Tania and Feychting, Maria and Ahlbom, Anders and Gaziano, J Michael and Giles, Graham G and Hallmans, Goran and Hankinson, Susan E and Hartge, Patricia and Henriksson, Roger and Inskip, Peter D and Johansen, Christoffer and Landgren, Annelie and McKean-Cowdin, Roberta and Michaud, Dominique S and Melin, Beatrice S and Peters, Ulrike and Ruder, Avima M and Sesso, Howard D and Severi, Gianluca and Shu, Xiao-Ou and Visvanathan, Kala and ... and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Institutionen för strålningsvetenskaper and Näringsforskning and Onkologi and Umeå universitet
Nature Genetics, ISSN 1061-4036, 06/2012, Volume 44, Issue 6, pp. 651 - 658
Journal Article
Gut, ISSN 0017-5749, 08/2017, Volume 66, Issue 8, pp. 1496 - 1506
ObjectiveWe investigated the mutational landscape of mammalian target of rapamycin (mTOR) signalling cascade in hepatocellular carcinomas (HCCs) with chronic... 
HEPATITIS B | GENE MUTATION | MUTATION SCREENING | HEPATOCELLULAR CARCINOMA | THERAPEUTIC TARGETS | HEPATOCELLULAR-CARCINOMA | MTORC1 | MICE | GASTROENTEROLOGY & HEPATOLOGY | PATHWAY | Neoplasm Transplantation | Antibiotics, Antineoplastic - pharmacology | Axin Protein - genetics | TOR Serine-Threonine Kinases - metabolism | Humans | Middle Aged | Male | Liver Neoplasms - chemistry | Tumor Suppressor Protein p53 - genetics | Young Adult | DNA Mutational Analysis | Carcinoma, Hepatocellular - genetics | Tumor Suppressor Proteins - genetics | Adult | Female | Carcinoma, Hepatocellular - chemistry | Nuclear Proteins - genetics | Tumor Stem Cell Assay | Cell Proliferation - genetics | Sirolimus - therapeutic use | Liver Neoplasms - genetics | Signal Transduction | Mutation Rate | Transcription Factors - genetics | Sirolimus - pharmacology | beta Catenin - genetics | Animals | Antibiotics, Antineoplastic - therapeutic use | Liver Neoplasms - metabolism | Cell Line, Tumor | Aged | Cell Proliferation - drug effects | Mice | Carcinoma, Hepatocellular - metabolism | Tumor Suppressor Proteins - analysis | Reports | Care and treatment | Hepatoma | Research | Gene mutations | TOR protein | Immunohistochemistry | Tuberous Sclerosis Complex 2 | Hepatocellular carcinoma | Hamartin | Infections | Genomes | Insulin-like growth factors | Kinases | TSC1 protein | Cancer therapies | Liver cancer | Signal transduction | Epidermal growth factor | Next-generation sequencing | Gastroenterology | Xenografts | Aggressive behavior | Colonies | Hypersensitivity | Tuberous sclerosis | Rapamycin | FDA approval | Patients | Ligands | Mutation | Tumors | 1506 | Hepatology
Journal Article
by Kato, Norihiro and Loh, Marie and Takeuchi, Fumihiko and Verweij, Niek and Wang, Xu and Zhang, Weihua and NKelly, Tanika and Saleheen, D and Lehne, Benjamin and Leach, Irene Mateo and ng, Alexander and Abbott, James and Wahl, Simone and Tan, Sian-Tsung and Scott, William R and Campanella, Gianluca and Chadeau-Hyam, Marc and Afzal, Uzma and Ahluwalia, Tarunveer Singh and Bonder, Marc and Chen, Ping and Dehghan, Abbas and Edwards, Todd L and Esko, Tõnu and Go, Min Jin and Harris, Sarah and Hartiala, Jaana and Kasela, Silva and Kasturiratne, Anuradhani and Khor, C.C and Kleber, Marcus and Li, Huaixing and Mok, Zuan Yu and Nakatochi, Masahiro and Sapari, Nur Sabrina and Saxena, Richa and Stewart, Alexane F and Stolk, Lisette and Tabara, Yasuharu and Teh, Ai Ling and Wu, Ying and Wu, Jer-Yuarn and Zhang, Yi and Aits, Imke and Da Silva Couto Alves, Alexessander and Das, Shikta and Dorajoo, Rajkumar and CHopewell, Jemma and Kim, Yun Kyoung and WKoivula, Robert and Luan, Jian'An and Lyytikäinen, Leo-Pekka and NNguyen, Quang and Pereira, Mark A and Postmus, Douwe and TRaitakari, Olli and Scannell Bryan, Molly and Scott, Robert and Sorice, R and Tragante, Vinicius and Traglia, Michela and White, Jon and Yamamoto, Ken and Zhang, Yonghong and Adair, Linda and Ahmed, Alauddin and Akiyama, Koichi and Asif, Rasheed and Aung, Tin and Barroso, Inês and Bjonnes, Anew and Braun, Timothy R and Cai, Hui and Chang, Li-Ching and Chen, C.-H and Cheng, Ching-Yu and Chong, Yap-Seng and Collins, Francis and Courtney, Regina and Davies, Gail and Delgado, G and Do, Loi D and Doevendans, Pieter and Gansevoort, Ron and Gao, Ying and Grammer, Tanja B and Grarup, Niels and Grewal, Jagvir and Gu, D and SWander, Gurpreet and Hartikainen, A.L and Hazen, Stanley and He, Jing and Heng, Chew-Kiat and Hixso, E. James Ames and Hofman, Albert and Hsu, Chris and Huang, Wei and Husemoen, Lise Lotte and Hwang, Joo-Yeon and ... and InterAct Consortium and BIOS-consortium and LifeLines Cohort Study and CARDIo GRAMplusCD and The InterAct Consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Allmänmedicin and Umeå universitet
Nature Genetics, ISSN 1061-4036, 11/2015, Volume 47, Issue 11, pp. 1282 - 1293
Journal Article
British Journal of Anaesthesia, ISSN 0007-0912, 11/2016, Volume 117, Issue 5, pp. 601 - 609
Journal Article