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American journal of human genetics, ISSN 0002-9297, 10/2016, Volume 99, Issue 4, pp. 877 - 885
The vast majority of coding variants are rare, and assessment of the contribution of rare variants to complex traits is hampered by low statistical power and... 
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Exome - genetics | Disease - genetics | Area Under Curve | DNA Mutational Analysis | Gene Frequency | Humans | ROC Curve | Software | Mutation, Missense - genetics | Technology application | Genetic code | Genetic variation | Health aspects | Genetic screening | Methods | Pathogens | Genetics | Mutation | Predictions | Index Medicus
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 03/2016, Volume 351, Issue 6278, pp. 1166 - 1171
Journal Article
by Al Olama, Ali Amin and Kote-Jarai, Zsofia and Berndt, Sonja I and Conti, David V and Schumacher, Fredrick and Han, Ying and Benlloch, Sara and Hazelett, Dennis J and Wang, Zhaoming and Saunders, Ed and Leongamornlert, Daniel and Lindstrom, Sara and Jugurnauth-Little, Sara and Dadaev, Tokhir and Tymrakiewicz, Malgorzata and Stram, Daniel O and Rand, Kristin and Wan, Peggy and Stram, Alex and Sheng, Xin and Pooler, Loreall C and Park, Karen and Xia, Lucy and Tyrer, Jonathan and Kolonel, Laurence N and Le Marchand, Loic and Hoover, Robert N and Machiela, Mitchell J and Yeager, Merideth and Burdette, Laurie and Chung, Charles C and Hutchinson, Amy and Yu, Kai and Goh, Chee and Ahmed, Mahbubl and Govindasami, Koveela and Guy, Michelle and Tammela, Teuvo L J and Auvinen, Anssi and Wahlfors, Tiina and Schleutker, Johanna and Visakorpi, Tapio and Leinonen, Katri A and Xu, Jianfeng and Aly, Markus and Donovan, Jenny and Travis, Ruth C and Key, Tim J and Siddiq, Afshan and Canzian, Federico and Khaw, Kay-Tee and Takahashi, Atsushi and Kubo, Michiaki and Pharoah, Paul and Pashayan, Nora and Weischer, Maren and Nordestgaard, Borge G and Nielsen, Sune F and Klarskov, Peter and Røder, Martin Andreas and Iversen, Peter and Thibodeau, Stephen N and McDonnell, Shannon K and Schaid, Daniel J and Stanford, Janet L and Kolb, Suzanne and Holt, Sarah and Knudsen, Beatrice and Coll, Antonio Hurtado and Gapstur, Susan M and Diver, W Ryan and Stevens, Victoria L and Maier, Christiane and Luedeke, Manuel and Herkommer, Kathleen and Rinckleb, Antje E and Strom, Sara S and Pettaway, Curtis and Yeboah, Edward D and Tettey, Yao and Biritwum, Richard B and Adjei, Andrew A and Tay, Evelyn and Truelove, Ann and Niwa, Shelley and Chokkalingam, Anand P and Cannon-Albright, Lisa and Cybulski, Cezary and Wokołorczyk, Dominika and Kluźniak, Wojciech and Park, Jong and Sellers, Thomas and Lin, Hui-Yi and Isaacs, William B and Partin, Alan W and Brenner, Hermann and Dieffenbach, Aida Karina and Stegmaier, Christa and Chen, Constance and Giovannucci, Edward L and ... and The PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium and The Breast and Prostate Cancer Cohort Consortium (BPC3) and The COGS (Collaborative Oncological Gene-environment Study) Consortium and The GAME-ON/ELLIPSE Consortium and Practical Prostate Canc Associatio and GAME-ON ELLIPSE Consortium and Breast Prostate Canc Cohort Consor and COGS Consortium and Breast and Prostate Cancer Cohort Consortium (BPC3) and GAME-ON/ELLIPSE Consortium and COGS (Collaborative Oncological Gene-environment Study) Consortium and PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium
Nature genetics, ISSN 1546-1718, 09/2014, Volume 46, Issue 10, pp. 1103 - 1109
Journal Article
by Zeggini, E and Weedon, M. N and Lindgren, C. M and Frayling, T. M and Elliott, K. S and Lango, H and Timpson, N. J and Perry, J. R. B and Rayner, N. W and Freathy, R. M and Barrett, J. C and Shields, B and Morris, A. P and Ellard, S and Groves, C. J and Harries, L. W and Marchini, J. L and Owen, K. R and Knight, B and Cardon, L. R and Walker, M and Hitman, G. A and Morris, A. D and Doney, A. S. F and Burton, P. R and Clayton, D. G and Craddock, N and Deloukas, P and Duncanson, A and Kwiatkowski, D. P and Ouwehand, W. H and Samani, N. J and Todd, J. A and Donnelly, P and Davison, D and Easton, D and Evans, D and Leung, H.-T and Spencer, C. C. A and Tobin, M. D and Attwood, A. P and Boorman, J. P and Cant, B and Everson, U and Hussey, J. M and Jolley, J. D and Knight, A. S and Koch, K and Meech, E and Nutland, S and Prowse, C. V and Stevens, H. E and Taylor, N. C and Walters, G. R and Walker, N. M and Watkins, N. A and Winzer, T and Jones, R. W and McArdle, W. L and Ring, S. M and Strachan, D. P and Pembrey, M and Breen, G and St. Clair, D and Caesar, S and Gordon-Smith, K and Jones, L and Fraser, C and Green, E. K and Grozeva, D and Hamshere, M. L and Holmans, P. A and Jones, I. R and Kirov, G and Moskvina, V and Nikolov, I and O'Donovan, M. C and Owen, M. J and Collier, D. A and Elkin, A and Farmer, A and Williamson, R and McGuffin, P and Young, A. H and Ferrier, I. N and Ball, S. G and Balmforth, A. J and Barrett, J. H and Bishop, D. T and Iles, M. M and Maqbool, A and Yuldasheva, N and Hall, A. S and Braund, P. S and Dixon, R. J and Mangino, M and Stevens, S and Thompson, J. R and Bredin, F and Tremelling, M and ... and The Wellcome Trust Case Control Consortium (WTCCC) and WTCCC and Wellcome Trust Case Control Consortium (WTCCC)
Science (American Association for the Advancement of Science), ISSN 1095-9203, 06/2007, Volume 316, Issue 5829, pp. 1336 - 1341
Journal Article
Arthritis & rheumatology (Hoboken, N.J.), ISSN 2326-5191, 05/2015, Volume 67, Issue 8, pp. 2011 - 2019
Journal Article
by Su, Zhan and Gay, Laura J and Strange, Amy and Palles, Claire and Band, Gavin and Whiteman, David C and Lescai, Francesco and Langford, Cordelia and Nanji, Manoj and Edkins, Sarah and van der Winkel, Anouk and Levine, David and Sasieni, Peter and Bellenguez, Céline and Howarth, Kimberley and Freeman, Colin and Trudgill, Nigel and Tucker, Art T and Pirinen, Matti and Peppelenbosch, Maikel P and van der Laan, Luc J W and Kuipers, Ernst J and Drenth, Joost P H and Peters, Wilbert H and Reynolds, John V and Kelleher, Dermot P and McManus, Ross and Grabsch, Heike and Prenen, Hans and Bisschops, Raf and Krishnadath, Kausila and Siersema, Peter D and van Baal, Jantine W P M and Middleton, Mark and Petty, Russell and Gillies, Richard and Burch, Nicola and Bhandari, Pradeep and Paterson, Stuart and Edwards, Cathryn and Penman, Ian and Vaidya, Kishor and Ang, Yeng and Murray, Iain and Patel, Praful and Ye, Weimin and Mullins, Paul and Wu, Anna H and Bird, Nigel C and Dallal, Helen and Shaheen, Nicholas J and Murray, Liam J and Koss, Konrad and Bernstein, Leslie and Romero, Yvonne and Hardie, Laura J and Zhang, Rui and Winter, Helen and Corley, Douglas A and Panter, Simon and Risch, Harvey A and Reid, Brian J and Sargeant, Ian and Gammon, Marilie D and Smart, Howard and Dhar, Anjan and McMurtry, Hugh and Ali, Haythem and Liu, Geoffrey and Casson, Alan G and Chow, Wong-Ho and Rutter, Matt and Tawil, Ashref and Morris, Danielle and Nwokolo, Chuka and Isaacs, Peter and Rodgers, Colin and Ragunath, Krish and MacDonald, Chris and Haigh, Chris and Monk, David and Davies, Gareth and Wajed, Saj and Johnston, David and Gibbons, Michael and Cullen, Sue and Church, Nicholas and Langley, Ruth and Griffin, Michael and Alderson, Derek and Deloukas, Panos and Hunt, Sarah E and Gray, Emma and Dronov, Serge and Potter, Simon C and Tashakkori-Ghanbaria, Avazeh and Anderson, Mark and Brooks, Claire and Blackwell, Jenefer M and Bramon, Elvira and ... and Wellcome Trust Case Control Consor and Esophageal Adenocarcinoma Genetics and Wellcome Trust Case Control Consortium 2 and Esophageal Adenocarcinoma Genetics Consortium and The Wellcome Trust Case Control Consortium 2 and The Esophageal Adenocarcinoma Genetics Consortium
Nature genetics, ISSN 1061-4036, 09/2012, Volume 44, Issue 10, pp. 1131 - 1136
Journal Article