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NATURE COMMUNICATIONS, ISSN 2041-1723, 06/2019, Volume 10, Issue 1, pp. 1 - 7
Hereditary retinal degenerations (HRDs) are Mendelian diseases characterized by progressive blindness and caused by ultra-rare mutations. In a genomic screen... 
RP1 | ALLELES | PROTEIN | GENE | MULTIDISCIPLINARY SCIENCES | DISEASE | RISK | MUTATIONS | IDENTIFICATION | RETINITIS-PIGMENTOSA | ASSOCIATION | Blindness | Alleles | Retinal degeneration | Insertion | Retina | Heredity | Mutation
Journal Article
Graefe's Archive for Clinical and Experimental Ophthalmology, ISSN 0721-832X, 07/2019, Volume 257, Issue 7, pp. 1411 - 1418
Journal Article
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ISSN 0146-0404, 07/2019, Volume 60, Issue 8, pp. 2781 - 2786
PURPOSE. To examine trends in the prevalence of myopia and myopic maculopathy in a general Japanese population. METHODS. Residents of a Japanese community aged... 
RISK-FACTORS | myopic maculopathy | VISUAL IMPAIRMENT | ADULTS | SINGAPORE | CLASSIFICATION | SECULAR TRENDS | CHINESE | BLINDNESS | epidemiology | LOW-VISION | myopia | OPHTHALMOLOGY | RETINOPATHY
Journal Article
Journal of Medical Genetics, ISSN 0022-2593, 2019, pp. 1 - 9
The genetic profile of retinitis pigmentosa (RP) in East Asian populations has not been well characterised. Therefore, we conducted a large-scale sequencing... 
retinitis pigmentosa | next-generation sequencing | genetic epidemiology
Journal Article
Journal Article
American journal of ophthalmology, 03/2019
To evaluate longer-term efficacy and safety of intravitreal aflibercept monotherapy (IAI) vs IAI plus rescue photodynamic therapy (IAI + rPDT) in polypoidal... 
Journal Article
Graefe's Archive for Clinical and Experimental Ophthalmology, ISSN 0721-832X, 3/2019, Volume 257, Issue 3, pp. 557 - 565
This study was conducted in order to develop a novel noninvasive system for measurement and imaging of the arterial oxygen density ratio (ODR) in the retinal... 
Medicine & Public Health | Retinal microcirculation region | Oxygen density ratio | Morphological closing operation | Ophthalmology | Line convergence index filter | Arterial phase | OXIMETRY | VESSEL DIAMETER | OPHTHALMOLOGY | HEALTHY | BLOOD-FLOW | SATURATION | Measurement | Specific gravity | Electronic cameras | Oxygen | Algorithms | Arterioles | Erythrocytes | Retina | Cameras | Arteries | Index Medicus
Journal Article
Ophthalmologica, ISSN 0030-3755, 03/2019, Volume 241, Issue 3, pp. 161 - 169
Purpose: To assess the efficacy and safety of sub-Tenon injection of triamcinolone acetonide (WP-0508ST) for the patients with diabetic macular edema (DME).... 
Research Article | WP-0508ST | Randomized clinical study | Sub-Tenon injection | Diabetic macular edema | Triamcinolone acetonide | DEPENDS | INFUSION | CAPSULE INJECTION | COHERENCE TOMOGRAPHIC PATTERNS | PLASMA | OPHTHALMOLOGY | INTRAVITREAL BEVACIZUMAB | RANIBIZUMAB | Index Medicus
Journal Article
PLOS ONE, ISSN 1932-6203, 02/2019, Volume 14, Issue 2, pp. e0213161 - e0213161
Purpose Abnormal fundus autofluorescence (FAF) potentially precedes onset of late age-related macular degeneration (AMD) in Caucasian patients. Many... 
LOW LUMINANCE | RISK-FACTORS | PIGMENT EPITHELIUM PHENOTYPES | VISUAL FUNCTION | MULTIDISCIPLINARY SCIENCES | CLASSIFICATION | PREVALENCE | MICROPERIMETRY | RANIBIZUMAB | GEOGRAPHIC ATROPHY | SUBFOVEAL CHOROIDAL NEOVASCULARIZATION | Macular degeneration | Usage | Diagnostic imaging | Research | Japanese | Health aspects | Methods
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 5376 - 10
Aberrant activation of Notch signaling contributes to the pathogenesis of several different types of cancer, and Notch pathway inhibitors may have significant... 
CELLS | MANGOSTANA | MULTIDISCIPLINARY SCIENCES | LEUKEMIA | GARCINIA-COWA | GAMMA-SECRETASE | XANTHONES | CANCER | TUMORS | Signal transduction | Nicastrin | Leukemia | Cytotoxicity | Notch protein | Secretase | Cancer
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 8070 - 7
In order to clarify the disease progression in retinitis pigmentosa (RP) and its related factors, reliable data on the changes in central visual function in RP... 
Eye | Statistical analysis | Retinitis pigmentosa | Visual field | Retina | Retinitis | Acuity | Visual perception
Journal Article
Journal Article
JCI insight, ISSN 2379-3708, 09/2018, Volume 3, Issue 18
Age-related macular degeneration (AMD), a progressive chronic disease of the central retina, is associated with aging and is a leading cause of blindness... 
Eicosanoids | Angiogenesis | Inflammation | G-protein coupled receptors | Macrophages
Journal Article