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Annals of Oncology, ISSN 0923-7534, 11/2016, Volume 27, Issue suppl_7
Journal Article
Drug Delivery System, ISSN 0913-5006, 2018, Volume 33, Issue 4, pp. 318 - 328
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2017, Volume 40, Issue 1, pp. 1 - 10
The liposome, a closed phospholipid bilayered vesicular system, has received considerable attention as a pharmaceutical carrier of great potential over the... 
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2019, Volume 1943, pp. 333 - 346
For the systemic application of nucleic acids [plasmid DNA (pDNA) and small interfering RNA (siRNA)], safe and efficient carriers that overcome the poor... 
Anti-PEG IgM | Enzyme-linked immunosorbent assay (ELISA) | Polyethylene glycol (PEG) | Accelerated blood clearance (ABC) phenomenon | PEGylated nanocarrier
Journal Article
Cancer Letters, ISSN 0304-3835, 2016, Volume 400, pp. 223 - 231
Abstract Metronomic chemotherapy is currently considered an emerging therapeutic option in clinical oncology. S-1, an oral formulation of Tegafur (TF), a... 
Hematology, Oncology and Palliative Medicine | RNAi | PEG-coated shRNA-lipoplex | Short hairpin RNA | Thymidylate synthase | S-1 | Colorectal cancer | THERAPEUTICS | DIHYDROPYRIMIDINE DEHYDROGENASE | RNA-INTERFERENCE | CHEMOTHERAPY | LUNG-CANCER | ONCOLOGY | GASTRIC-CANCER | IN-VIVO | EXPRESSION LEVELS | TUMOR-GROWTH | THYMIDINE PHOSPHORYLASE | Administration, Metronomic | Apoptosis - drug effects | Colorectal Neoplasms - genetics | Humans | Male | Antimetabolites, Antineoplastic - administration & dosage | Colorectal Neoplasms - therapy | Transfection | RNA Interference | Time Factors | Antimetabolites, Antineoplastic - metabolism | Oxonic Acid - metabolism | Colorectal Neoplasms - enzymology | Thymidylate Synthase - metabolism | Oxonic Acid - administration & dosage | Thymidylate Synthase - genetics | RNAi Therapeutics - methods | Xenograft Model Antitumor Assays | Animals | Tegafur - metabolism | Tumor Burden - drug effects | Mice, Nude | Cell Line, Tumor | Tegafur - administration & dosage | Cell Proliferation - drug effects | Mice, Inbred BALB C | Colorectal Neoplasms - pathology | Drug Combinations | Chemotherapy | RNA | Cancer | Polyethylenes | 5-Fluorouracil | Toxicity | Tegafur | Lung cancer | Colorectal carcinoma | Metastasis | Kinases | Drug resistance | Cancer therapies | Metastases | Anticancer properties | Proteins | Polyethylene glycol | Xenografts | Chemical synthesis | Drug dosages | Dosing | RNA-mediated interference | Gene expression | Ribonucleic acid--RNA | Antitumor activity | Combined treatment | Viral infections | Apoptosis | Index Medicus
Journal Article
Cancer Letters, ISSN 0304-3835, 2016, Volume 400, pp. 232 - 242
Abstract The therapeutic concept of administering chemotherapeutic agents continuously at lower doses, relative to the maximum tolerated dose (MTD) without... 
Hematology, Oncology and Palliative Medicine | Nanoparticles | Tumor priming | Maximum tolerated dose | Liposomes | Dosing schedule | Metronomic chemotherapy | ADVANCED HEPATOCELLULAR-CARCINOMA | PEGYLATED LIPOSOMAL DOXORUBICIN | LOW-DOSE CYCLOPHOSPHAMIDE | STEM-LIKE CELLS | ONCOLOGY | ACCELERATED BLOOD CLEARANCE | METASTATIC BREAST-CANCER | COATED CATIONIC LIPOSOMES | RECURRENT OVARIAN-CANCER | COLORECTAL TUMOR-MODEL | ENDOTHELIAL GROWTH-FACTOR | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Administration, Metronomic | Humans | Neoplasms - blood supply | Drug Carriers | Neoplasms - drug therapy | Dose-Response Relationship, Drug | Angiogenesis Inhibitors - administration & dosage | Maximum Tolerated Dose | Animals | Neoplasms - immunology | Nanomedicine - methods | Drug Compounding | Neoplasms - pathology | Angiogenesis Inhibitors - adverse effects | Angiogenesis Inhibitors - chemistry | Drugs | Antimitotic agents | Chemotherapy | Drug delivery systems | Pharmacy | Drugstores | Development and progression | Antineoplastic agents | Cancer | Vehicles | CD8 antigen | Cytotoxicity | Metastasis | Drug resistance | Cancer therapies | Blood | Anticancer properties | Metastases | Angiogenesis | Breast carcinoma | Bone marrow | CD25 antigen | Inhibition | Drug dosages | Antigens | Macromolecules | Blood vessels | Exposure | Ablation | Carriers | Inhibitors | Surveillance | Antigen-presenting cells | Stem cells | Angiogenesis inhibitors | Accessibility | Toxicity | Dormancy | Lymphocytes | Modulation | Immune system | Effectiveness | Tumor cells | Vessels | Pharmacology | Breast cancer | Inflammation | Permeability | CD4 antigen | Hypotheses | Cell death | Antigen (tumor-associated) | Breast | Antitumor activity | Microenvironments | Cations | Pharmacokinetics | Tumors | Apoptosis | Index Medicus
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2017, Volume 40, Issue 5, pp. 665 - 674
A 2% commercially available, milky-white, rebamipide micro-particle suspension is used to treat dry eyes, and it causes short-term blurring of the patient's... 
Journal Article
Biological & Pharmaceutical Bulletin, ISSN 0918-6158, 06/2013, Volume 36, Issue 6, p. 889
  In contrast to the general assumption that polyethyleneglycol (PEG)-conjugated substances lack immunogenicity and antigenic, it has been reported that they... 
Journal Article
Biological & Pharmaceutical Bulletin, ISSN 0918-6158, 05/2013, Volume 36, Issue 5, p. 692
  Nanocarrier-based cancer chemotherapeutics are thought to increase therapeutic efficiency and reduce the side effects of associated chemotherapeutic agents... 
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2018, Volume 41, Issue 5, pp. 733 - 742
Exosomes are tiny extracellular vesicles that are usually harvested in small quantities. Such small yield has been an obstacle for the expansion of the basic... 
exosome secretion | PEGylation | cationic lipid | liposome | stimulation | Liposome | Stimulation | Exosome secretion | Cationic lipid | DENSITY | DRUG-DELIVERY | IN-VIVO | NANOPARTICLE | MICROVESICLES | PHARMACOLOGY & PHARMACY | LIPOSOMES | Formulations | Biological properties | Drug delivery systems | Tumor cells | Secretion | Drug delivery | Tumor cell lines | Exosomes | Vesicles | Cations | Yield | Liposomes | Physicochemical properties | Tumors
Journal Article
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2016, Volume 39, Issue 9, pp. 1555 - 1558
Hydrodynamic tail vein injection was considered an in vivo transfection method that yields a higher level of gene expression mainly in the liver. This method... 
Journal Article