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PLoS ONE, ISSN 1932-6203, 01/2019, Volume 14, Issue 1, p. e0210439
Mutations of the gene encoding RPE65 cause Leber congenital amaurosis (LCA) retinitis pigmentosa (RP). The optical coherence tomography (OCT) is increasingly... 
Electroretinography | Genetically modified mice | Usage | Retinitis pigmentosa | Models | Research | Leber's congenital amaurosis | Optical tomography
Journal Article
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2016, Volume 478, Issue 4
Intracellular Ca.sup.2+-dependent cysteine proteases such as calpains have been suggested as critical factors in retinal ganglion cell (RGC) death. However, it... 
Glaucoma | Prevention | Medical colleges | Cysteine | Peptides | Calpain | Ophthalmology | Ganglion
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2016, Volume 478, Issue 4, pp. 1700 - 1705
Intracellular Ca2+-dependent cysteine proteases such as calpains have been suggested as critical factors in retinal ganglion cell (RGC) death. However, it is... 
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 12/2009, Volume 1793, Issue 12, pp. 1848 - 1859
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 10/2008, Volume 1783, Issue 10, pp. 1955 - 1963
Calpains, calcium-dependent neutral cystein proteases, are involved in a variety of cellular processes. We have previously shown the characteristics of... 
Mitochondrial μ-calpain | Mitochondrial intermembrane space | ERp57 | MALDI-TOFMS | Apoptosis-inducing factor (AIF)
Journal Article
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 03/2011, Volume 507, Issue 2, p. 254
a* Mitochondrial m-calpain large subunit localizes mainly in the mitochondrial outer membrane (OM). a* Free calpain small subunits are present in the... 
Calpain | Universities and colleges
Journal Article
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 03/2011, Volume 507, Issue 2, pp. 254 - 261
Although mitochondrial [micro]- and m-calpains play significant roles in apoptotic cell death, their activating mechanisms have not been determined. The... 
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2015, Volume 10, Issue 6, p. e0130986
Journal Article
Experimental Eye Research, ISSN 0014-4835, 2010, Volume 91, Issue 3, pp. 353 - 361
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e71650
Mitochondrial μ-calpain and apoptosis-inducing factor (AIF)-dependent photoreceptor cell death has been seen in several rat and mouse models of retinitis... 
Calpain - metabolism | Intravitreal Injections | Photoreceptor Cells, Vertebrate - drug effects | Apoptosis Inducing Factor - antagonists & inhibitors | Mitochondrial Proteins - genetics | Protein Transport - drug effects | Calpain - genetics | Rhodopsin - metabolism | Cell Nucleus - metabolism | Peptides - chemical synthesis | Mitochondrial Proteins - metabolism | Ophthalmic Solutions | Cell Death - drug effects | Apoptosis Inducing Factor - metabolism | Disease Models, Animal | Electroretinography | In Situ Nick-End Labeling | Rats, Transgenic | Signal Transduction | Mitochondrial Proteins - antagonists & inhibitors | Retinitis Pigmentosa - drug therapy | Gene Expression Regulation | Rats | Retinitis Pigmentosa - genetics | Retinitis Pigmentosa - metabolism | Mitochondria - metabolism | Mitochondria - drug effects | Apoptosis Inducing Factor - genetics | Peptides - pharmacology | Animals | Rhodopsin - genetics | Mutation | Photoreceptor Cells, Vertebrate - metabolism | Cell Nucleus - drug effects | Photoreceptor Cells, Vertebrate - pathology | Retinitis Pigmentosa - pathology | Calpain - antagonists & inhibitors | Immunohistochemistry | Animal models | Retinitis pigmentosa | MERTK gene | Transgenic | Retina | Mitochondria | Rodents | Degeneration | Inhibition | Medical personnel | Translocation | Rhodopsin | Apoptosis-inducing factor | Mortality | Calpain | Injection | Nuclear transport | Electroretinograms | DNA nucleotidylexotransferase | Cell death | Retinal degeneration | Retinitis | Topical application | Apoptosis
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 11/2012, Volume 1822, Issue 11, pp. 1783 - 1795
Mitochondrial μ-calpain initiates apoptosis-inducing factor (AIF)-dependent apoptosis in retinal photoreceptor degeneration. Mitochondrial μ-calpain inhibitors... 
Calpain | Mitochondria | Retinal photoreceptor degeneration | Retinitis pigmentosa | Peptide | Apoptosis-inducing factor
Journal Article