Cancer Science, ISSN 1347-9032, 01/2018, Volume 109, Issue 1, pp. 132 - 140
Xantohumol, a prenylated chalcone from hops (Humulus lupulus L.), has been shown to inhibit proliferation in some cancers. However, little is known regarding...
pancreatic cancer | interleukin‐8 | NF‐κB | xanthohumol | angiogenesis | NF-κB | interleukin-8 | SURVIVAL | APOPTOSIS | SAFETY | ADENOCARCINOMA | ACIDOSIS | CELL-LINES | GEMCITABINE | INTERLEUKIN-8 EXPRESSION | NF-kappa B | HOPS HUMULUS-LUPULUS | ONCOLOGY | ENDOTHELIAL GROWTH-FACTOR | Cell Survival - drug effects | Interleukin-8 - genetics | Pancreatic Neoplasms - metabolism | Coculture Techniques | Humans | Propiophenones - pharmacology | Angiogenesis Inhibitors - pharmacology | Pancreatic Neoplasms - genetics | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Transcription Factor RelA - genetics | Pancreatic Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Angiogenesis Inhibitors - administration & dosage | Animals | Transcription Factor RelA - metabolism | Propiophenones - administration & dosage | Cell Line, Tumor | Flavonoids - administration & dosage | Cell Proliferation - drug effects | Flavonoids - pharmacology | Mice | Gene Expression Regulation, Neoplastic - drug effects | Interleukin-8 - metabolism | Immunohistochemistry | Cytokines | Xanthohumol | Hops | Metastasis | Tumor cell lines | Gene expression | Cancer therapies | Endothelial cells | Studies | Angiogenesis | Cell activation | Cell growth | Pancreatic cancer | Transcription activation | Cell lines | Xenografts | Vascular endothelial growth factor | Umbilical vein | Tumors | Original
pancreatic cancer | interleukin‐8 | NF‐κB | xanthohumol | angiogenesis | NF-κB | interleukin-8 | SURVIVAL | APOPTOSIS | SAFETY | ADENOCARCINOMA | ACIDOSIS | CELL-LINES | GEMCITABINE | INTERLEUKIN-8 EXPRESSION | NF-kappa B | HOPS HUMULUS-LUPULUS | ONCOLOGY | ENDOTHELIAL GROWTH-FACTOR | Cell Survival - drug effects | Interleukin-8 - genetics | Pancreatic Neoplasms - metabolism | Coculture Techniques | Humans | Propiophenones - pharmacology | Angiogenesis Inhibitors - pharmacology | Pancreatic Neoplasms - genetics | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Transcription Factor RelA - genetics | Pancreatic Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Angiogenesis Inhibitors - administration & dosage | Animals | Transcription Factor RelA - metabolism | Propiophenones - administration & dosage | Cell Line, Tumor | Flavonoids - administration & dosage | Cell Proliferation - drug effects | Flavonoids - pharmacology | Mice | Gene Expression Regulation, Neoplastic - drug effects | Interleukin-8 - metabolism | Immunohistochemistry | Cytokines | Xanthohumol | Hops | Metastasis | Tumor cell lines | Gene expression | Cancer therapies | Endothelial cells | Studies | Angiogenesis | Cell activation | Cell growth | Pancreatic cancer | Transcription activation | Cell lines | Xenografts | Vascular endothelial growth factor | Umbilical vein | Tumors | Original
Journal Article
Nature, ISSN 0028-0836, 05/2006, Volume 441, Issue 7089, pp. 46 - 52
Sister chromatid cohesion, mediated by a complex called cohesin, is crucial-particularly at centromeres-for proper chromosome segregation in mitosis and...
MITOSIS | YEAST | SISTER CHROMATIDS | MEI-S332 | CENTROMERIC COHESION | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | MEIOSIS-I | CHROMOSOME SEGREGATION | POLO-LIKE KINASE | OKADAIC ACID | Phosphorylation | Chromosomal Proteins, Non-Histone - metabolism | Mitosis | Humans | Phosphoprotein Phosphatases - metabolism | Cell Cycle Proteins - metabolism | Multiprotein Complexes - genetics | Nuclear Proteins - metabolism | Meiosis | Centromere - metabolism | Phosphoproteins - metabolism | Chromatids - metabolism | Schizosaccharomyces - genetics | Multiprotein Complexes - metabolism | Schizosaccharomyces - metabolism | Phosphoprotein Phosphatases - genetics | Schizosaccharomyces pombe Proteins - metabolism | Cell Cycle Proteins - genetics | Phosphoprotein Phosphatases - classification | Protein Binding | HeLa Cells | Protein Phosphatase 2 | Chromosome Pairing | Schizosaccharomyces - cytology | Proteins | Cell division | Molecular biology | Chromosomes
MITOSIS | YEAST | SISTER CHROMATIDS | MEI-S332 | CENTROMERIC COHESION | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | MEIOSIS-I | CHROMOSOME SEGREGATION | POLO-LIKE KINASE | OKADAIC ACID | Phosphorylation | Chromosomal Proteins, Non-Histone - metabolism | Mitosis | Humans | Phosphoprotein Phosphatases - metabolism | Cell Cycle Proteins - metabolism | Multiprotein Complexes - genetics | Nuclear Proteins - metabolism | Meiosis | Centromere - metabolism | Phosphoproteins - metabolism | Chromatids - metabolism | Schizosaccharomyces - genetics | Multiprotein Complexes - metabolism | Schizosaccharomyces - metabolism | Phosphoprotein Phosphatases - genetics | Schizosaccharomyces pombe Proteins - metabolism | Cell Cycle Proteins - genetics | Phosphoprotein Phosphatases - classification | Protein Binding | HeLa Cells | Protein Phosphatase 2 | Chromosome Pairing | Schizosaccharomyces - cytology | Proteins | Cell division | Molecular biology | Chromosomes
Journal Article
High Pressure Research, ISSN 0895-7959, 04/2019, Volume 39, Issue 2, pp. 218 - 224
High pressure native polyacrylamide gel electrophoresis has been designed to visualize the dissociation/association process of protein complexes. This paper...
lactate dehydrogenase | High pressure native PAGE | Ferguson plot analysis | oligomer dissociation | Proteins | Image analysis | Gels | Electrophoresis | Lactate dehydrogenase | Pressurization | Pressurizing | Quantitative analysis
lactate dehydrogenase | High pressure native PAGE | Ferguson plot analysis | oligomer dissociation | Proteins | Image analysis | Gels | Electrophoresis | Lactate dehydrogenase | Pressurization | Pressurizing | Quantitative analysis
Journal Article
Nature, ISSN 0028-0836, 01/2015, Volume 517, Issue 7535, pp. 466 - 471
The kinetochore is the crucial apparatus regulating chromosome segregation in mitosis and meiosis. Particularly in meiosis I, unlike in mitosis, sister...
FISSION YEAST | CENTROMERIC COHESION | MULTIDISCIPLINARY SCIENCES | SINGLE-DIVISION MEIOSIS | HOMOLOGOUS CHROMOSOMES | PROTEIN PHOSPHATASE 2A | CHROMOSOME SEGREGATION | MAMMALIAN OOCYTES | KINASE CDC5 | MONOPOLAR ATTACHMENT | AURORA-B | Proto-Oncogene Proteins - metabolism | Chromosomal Proteins, Non-Histone - metabolism | Kinetochores - metabolism | Humans | Cell Cycle Proteins - metabolism | Molecular Sequence Data | Male | Meiosis | Centromere - metabolism | Chromosomal Proteins, Non-Histone - deficiency | Chromosomal Proteins, Non-Histone - genetics | Infertility - genetics | Animals | Infertility - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Schizosaccharomyces pombe Proteins - metabolism | Conserved Sequence | Female | Mice | Protein-Serine-Threonine Kinases - metabolism | DNA replication | Mitosis | Chromosomes | Analysis | Proteins | Chromatin | Yeast | Genes | Infertility | Cell division | Mammals | Females | Defects
FISSION YEAST | CENTROMERIC COHESION | MULTIDISCIPLINARY SCIENCES | SINGLE-DIVISION MEIOSIS | HOMOLOGOUS CHROMOSOMES | PROTEIN PHOSPHATASE 2A | CHROMOSOME SEGREGATION | MAMMALIAN OOCYTES | KINASE CDC5 | MONOPOLAR ATTACHMENT | AURORA-B | Proto-Oncogene Proteins - metabolism | Chromosomal Proteins, Non-Histone - metabolism | Kinetochores - metabolism | Humans | Cell Cycle Proteins - metabolism | Molecular Sequence Data | Male | Meiosis | Centromere - metabolism | Chromosomal Proteins, Non-Histone - deficiency | Chromosomal Proteins, Non-Histone - genetics | Infertility - genetics | Animals | Infertility - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Schizosaccharomyces pombe Proteins - metabolism | Conserved Sequence | Female | Mice | Protein-Serine-Threonine Kinases - metabolism | DNA replication | Mitosis | Chromosomes | Analysis | Proteins | Chromatin | Yeast | Genes | Infertility | Cell division | Mammals | Females | Defects
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 08/2017, Volume 56, Issue 32, pp. 9371 - 9375
The three‐dimensional (3D) distribution and oxidation state of a Pt cathode catalyst in a practical membrane electrode assembly (MEA) were visualized in a...
computed tomography | XANES imaging | polymer electrolyte fuel cell | catalyst degradation | Pt cathode catalyst | RESOLVED XAFS TECHNIQUES | PARTICLE | HIGH HUMIDITY CONDITIONS | CHEMISTRY, MULTIDISCIPLINARY | COMPUTED-TOMOGRAPHY | DURABILITY | PHASE | PERFORMANCE DEGRADATION | PEFC | PT/C | REAL-TIME | CT imaging | Electrolytes | Polymer industry | Polymers | Fuel cell industry | Fuel cells | Spectroscopy | Catalysts | Migration | Accelerated tests | Fuel technology | Fuels | Degradation | Valence | Computed tomography | Platinum | Oxidation
computed tomography | XANES imaging | polymer electrolyte fuel cell | catalyst degradation | Pt cathode catalyst | RESOLVED XAFS TECHNIQUES | PARTICLE | HIGH HUMIDITY CONDITIONS | CHEMISTRY, MULTIDISCIPLINARY | COMPUTED-TOMOGRAPHY | DURABILITY | PHASE | PERFORMANCE DEGRADATION | PEFC | PT/C | REAL-TIME | CT imaging | Electrolytes | Polymer industry | Polymers | Fuel cell industry | Fuel cells | Spectroscopy | Catalysts | Migration | Accelerated tests | Fuel technology | Fuels | Degradation | Valence | Computed tomography | Platinum | Oxidation
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 09/2016, Volume 55, Issue 39, pp. 12022 - 12025
The spatial distribution of Ce3+ and Ce4+ in each particle of Ce2Zr2Ox in a three‐way conversion catalyst system was successfully imaged during an oxygen...
heterogeneous catalysis | oxygen storage capacity | XAFS imaging | structure–activity relationships | ceria–zirconia | VISUALIZATION | OXIDATION | REDOX BEHAVIOR | HETEROGENEITIES | TIME | CHEMISTRY, MULTIDISCIPLINARY | EXHAUST CATALYSTS | X-RAY NANOTOMOGRAPHY | ceria-zirconia | structure-activity relationships | SOLIDS | OXIDES | XAFS | Cerium | Heterogeneous catalysis | Zirconium | Zirconium oxide | Atoms & subatomic particles | Diffusion | Oxygen
heterogeneous catalysis | oxygen storage capacity | XAFS imaging | structure–activity relationships | ceria–zirconia | VISUALIZATION | OXIDATION | REDOX BEHAVIOR | HETEROGENEITIES | TIME | CHEMISTRY, MULTIDISCIPLINARY | EXHAUST CATALYSTS | X-RAY NANOTOMOGRAPHY | ceria-zirconia | structure-activity relationships | SOLIDS | OXIDES | XAFS | Cerium | Heterogeneous catalysis | Zirconium | Zirconium oxide | Atoms & subatomic particles | Diffusion | Oxygen
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 10/2012, Volume 51, Issue 41, pp. 10311 - 10314
Four‐dimensional visualization of Pt/C cathode catalyst layers in membrane electrode assemblies (MEAs) were successfully performed by a newly developed method,...
fuel cells | laminography | catalyst degradation | XANES | imaging | WATER DISTRIBUTION | RADIOGRAPHY | RAY | COMPUTED LAMINOGRAPHY | MICROSCOPY | CHEMISTRY, MULTIDISCIPLINARY | DURABILITY | LIQUID WATER | DEGRADATION | DIFFRACTION | NANOSCALE | Particle accelerators | Nuclear radiation | Fuel cell industry | Fuel cells | Electrolytes | Energy development | Universities and colleges | Polymer industry | Polymers | Cells | Electrodes | Fine structure | Visualization | Catalysts | Platinum | X-rays | Cathodes | Three dimensional
fuel cells | laminography | catalyst degradation | XANES | imaging | WATER DISTRIBUTION | RADIOGRAPHY | RAY | COMPUTED LAMINOGRAPHY | MICROSCOPY | CHEMISTRY, MULTIDISCIPLINARY | DURABILITY | LIQUID WATER | DEGRADATION | DIFFRACTION | NANOSCALE | Particle accelerators | Nuclear radiation | Fuel cell industry | Fuel cells | Electrolytes | Energy development | Universities and colleges | Polymer industry | Polymers | Cells | Electrodes | Fine structure | Visualization | Catalysts | Platinum | X-rays | Cathodes | Three dimensional
Journal Article
The American Journal of Geriatric Psychiatry, ISSN 1064-7481, 03/2019, Volume 27, Issue 3, pp. 280 - 286
Epidemiologic studies have demonstrated that depression is a risk factor for dementia. In particular, dementia with Lewy bodies (DLB) has been noted to be...
depression | major depressive disorder | serum | α-synuclein | Dementia | Lewy body | PSYCHIATRY | RISK | alpha-synuclein | CEREBROSPINAL-FLUID | GERIATRICS & GERONTOLOGY | MULTIPLE SYSTEM ATROPHY | PLASMA | ELEVATED LEVELS | CSF | GERONTOLOGY | DISCRIMINATE | LEWY BODIES | PARKINSONS-DISEASE
depression | major depressive disorder | serum | α-synuclein | Dementia | Lewy body | PSYCHIATRY | RISK | alpha-synuclein | CEREBROSPINAL-FLUID | GERIATRICS & GERONTOLOGY | MULTIPLE SYSTEM ATROPHY | PLASMA | ELEVATED LEVELS | CSF | GERONTOLOGY | DISCRIMINATE | LEWY BODIES | PARKINSONS-DISEASE
Journal Article
Angewandte Chemie - International Edition, ISSN 1433-7851, 2016, Volume 55, Issue 39, pp. 12022 - 12025
Journal Article
Neurologia medico-chirurgica, ISSN 0470-8105, 2016, Volume 56, Issue 3, pp. 132 - 140
Neonatal neuro-intervention is challenging. The purpose of this article is to report the neuro-intervention for the neonates with brain arteriovenous fistulas...
body weight | neuro-intervention | neonate | access route | arteriovenous fistula | Access route | Arteriovenous fistula | Neonate | Neuro-intervention | Body weight | SURGERY | CATHETERIZATION | GALEN MALFORMATION | MANAGEMENT | NEWBORN | EMBOLIZATION | CLINICAL NEUROLOGY | CHILDREN | ANGIOGRAPHY | ENDOVASCULAR TREATMENT | INFANTS | VEIN | Arteriovenous Fistula - complications | Arteriovenous Fistula - surgery | Follow-Up Studies | Humans | Heart Diseases - complications | Female | Male | Treatment Outcome | Neurosurgical Procedures - methods | Retrospective Studies | Heart Diseases - congenital | Infant, Newborn | Original
body weight | neuro-intervention | neonate | access route | arteriovenous fistula | Access route | Arteriovenous fistula | Neonate | Neuro-intervention | Body weight | SURGERY | CATHETERIZATION | GALEN MALFORMATION | MANAGEMENT | NEWBORN | EMBOLIZATION | CLINICAL NEUROLOGY | CHILDREN | ANGIOGRAPHY | ENDOVASCULAR TREATMENT | INFANTS | VEIN | Arteriovenous Fistula - complications | Arteriovenous Fistula - surgery | Follow-Up Studies | Humans | Heart Diseases - complications | Female | Male | Treatment Outcome | Neurosurgical Procedures - methods | Retrospective Studies | Heart Diseases - congenital | Infant, Newborn | Original
Journal Article
The Chemical Record, ISSN 1527-8999, 07/2019, Volume 19, Issue 7, pp. 1380 - 1392
Three‐dimensional imaging using X‐ray as a probe is state‐of‐the‐art for the characterization of heterogeneous materials. In addition to simple imaging of...
Tomography | Operando analysis | Laminography | Catalyst | PEFC | CHEMICAL CONTRAST | RESOLUTION | X-RAY-FLUORESCENCE | ELECTROLYTE FUEL-CELLS | CHEMISTRY, MULTIDISCIPLINARY | COMPUTED-TOMOGRAPHY | TIME-RESOLVED XAFS | TRANSMISSION | STRUCTURAL KINETICS | ABSORPTION | PT/C | Spectroscopy | Medical imaging | Catalysts | Fuel technology | Functional materials | Fine structure | Organic chemistry | Valence | Maps | Computed tomography | Ultrastructure | Morphology | Catalysis | Proton exchange membrane fuel cells | Cathodes | Structure-function relationships
Tomography | Operando analysis | Laminography | Catalyst | PEFC | CHEMICAL CONTRAST | RESOLUTION | X-RAY-FLUORESCENCE | ELECTROLYTE FUEL-CELLS | CHEMISTRY, MULTIDISCIPLINARY | COMPUTED-TOMOGRAPHY | TIME-RESOLVED XAFS | TRANSMISSION | STRUCTURAL KINETICS | ABSORPTION | PT/C | Spectroscopy | Medical imaging | Catalysts | Fuel technology | Functional materials | Fine structure | Organic chemistry | Valence | Maps | Computed tomography | Ultrastructure | Morphology | Catalysis | Proton exchange membrane fuel cells | Cathodes | Structure-function relationships
Journal Article
Human Pathology, ISSN 0046-8177, 02/2019, Volume 84, pp. 155 - 163
Immunohistochemical staining with anti–β-catenin antibody has been applied as a diagnostic tool for desmoid-type fibromatoses (DFs). In recent years, specific...
β-Catenin | CTNNB1 mutation | Immunohistochemical staining | Desmoid-type fibromatosis | Multi-institutional study | SERIES | beta-Catenin | MUTATIONS | PATHOLOGY | TUMORS | GENE CTNNB1 | Polymerase chain reaction | Pathology | Mutation | Deoxyribonucleic acid--DNA | Age | Cancer | Abdomen | Tumors
β-Catenin | CTNNB1 mutation | Immunohistochemical staining | Desmoid-type fibromatosis | Multi-institutional study | SERIES | beta-Catenin | MUTATIONS | PATHOLOGY | TUMORS | GENE CTNNB1 | Polymerase chain reaction | Pathology | Mutation | Deoxyribonucleic acid--DNA | Age | Cancer | Abdomen | Tumors
Journal Article
Microscopy and Microanalysis, ISSN 1431-9276, 08/2018, Volume 24, Issue S2, pp. 442 - 443
Journal Article
No shinkei geka. Neurological surgery, ISSN 0301-2603, 08/2013, Volume 41, Issue 8, p. 731
Journal Article
Neurological Surgery, ISSN 0301-2603, 08/2013, Volume 41, Issue 8, pp. 731 - 742
Journal Article
Journal of Human Genetics, ISSN 1434-5161, 01/2014, Volume 59, Issue 1, pp. 37 - 41
To describe clinical presentations of hereditary hemorrhagic telangiectasia (HHT) patients in Japan. There were 80 patients (40 men and 40 women, age 2-78,...
phenotype | Genotype | hereditary hemorrhagic telangiectasia | Japanese | POPULATION | ENDOGLIN | LOCUS | genotype | MAPS | GENE | DANISH PATIENTS | GENETICS & HEREDITY | MUTATIONS | ENG | Humans | Japan | Middle Aged | Asian Continental Ancestry Group - genetics | Child, Preschool | Male | Telangiectasia, Hereditary Hemorrhagic - genetics | Antigens, CD - genetics | Young Adult | Endoglin | Telangiectasia, Hereditary Hemorrhagic - diagnosis | Smad4 Protein - genetics | Activin Receptors, Type II - genetics | Adolescent | Adult | Female | Aged | Mutation | Child | Receptors, Cell Surface - genetics
phenotype | Genotype | hereditary hemorrhagic telangiectasia | Japanese | POPULATION | ENDOGLIN | LOCUS | genotype | MAPS | GENE | DANISH PATIENTS | GENETICS & HEREDITY | MUTATIONS | ENG | Humans | Japan | Middle Aged | Asian Continental Ancestry Group - genetics | Child, Preschool | Male | Telangiectasia, Hereditary Hemorrhagic - genetics | Antigens, CD - genetics | Young Adult | Endoglin | Telangiectasia, Hereditary Hemorrhagic - diagnosis | Smad4 Protein - genetics | Activin Receptors, Type II - genetics | Adolescent | Adult | Female | Aged | Mutation | Child | Receptors, Cell Surface - genetics
Journal Article
ChemPhysChem, ISSN 1439-4235, 06/2014, Volume 15, Issue 8, pp. 1563 - 1568
The cerium oxidation states in single catalyst particles of Pt/Ce2Zr2Ox (x=7 to 8) were investigated by spatially resolved nano X‐ray absorption fine structure...
single particles | ceria‐zirconia catalyst | oxygen storage capacity | nano X‐ray absorption fine structure | imaging | ceria-zirconia catalyst | nano X-ray absorption fine structure | ACTIVE PHASE EVOLUTION | LOCALIZATION | CRYSTAL-STRUCTURE | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | CHEMISTRY, PHYSICAL | TIME | COPPER | RAY | CO OXIDATION | SPECTROSCOPY | SURFACE | Cerium | Oxidation-reduction reaction | Zirconium oxide | Nuclear radiation | Fuel cells
single particles | ceria‐zirconia catalyst | oxygen storage capacity | nano X‐ray absorption fine structure | imaging | ceria-zirconia catalyst | nano X-ray absorption fine structure | ACTIVE PHASE EVOLUTION | LOCALIZATION | CRYSTAL-STRUCTURE | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | CHEMISTRY, PHYSICAL | TIME | COPPER | RAY | CO OXIDATION | SPECTROSCOPY | SURFACE | Cerium | Oxidation-reduction reaction | Zirconium oxide | Nuclear radiation | Fuel cells
Journal Article