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1. Full Text Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals
by Takahashi, Kumiko and Yamagata, Kumi and Ohsawa, Ikuroh and Ohta, Shigeo and Ishikawa, Masahiro and Asoh, Sadamitsu and Nishimaki, Kiyomi and Katsura, Ken-ichiro and Katayama, Yasuo and Watanabe, Megumi
Nature Medicine, ISSN 1078-8956, 06/2007, Volume 13, Issue 6, pp. 688 - 694
Acute oxidative stress induced by ischemia-reperfusion or inflammation causes serious damage to tissues, and persistent oxidative stress is accepted as one of... 
MEDICINE, RESEARCH & EXPERIMENTAL | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSIENT FOCAL ISCHEMIA | MITOCHONDRIA | INJURY | DEFICIENCY | CELL-DEATH | CELL BIOLOGY | CALCIUM | DISEASE | CEREBRAL-ISCHEMIA | BRAIN | Reperfusion Injury - therapy | Hydroxyl Radical - toxicity | Oxidation-Reduction | Humans | Administration, Inhalation | Rats | Male | Hydroxyl Radical - metabolism | PC12 Cells | Rats, Sprague-Dawley | Antioxidants - therapeutic use | Animals | Antioxidants - administration & dosage | Membrane Potential, Mitochondrial - physiology | Hydrogen - administration & dosage | Hydrogen - therapeutic use | Hydroxyl Radical - antagonists & inhibitors | Cerebral Infarction - therapy | Disease Models, Animal | Antioxidants | Brain damage | Free radicals | Hydrogen | Medical treatment
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2. Full Text The quiescent intracluster medium in the core of the Perseus cluster
by Aharonian, Felix and Akamatsu, Hiroki and Akimoto, Fumie and Allen, Steven W and Anabuki, Naohisa and Angelini, Lorella and Arnaud, Keith and Audard, Marc and Awaki, Hisamitsu and Axelsson, Magnus and Bamba, Aya and Bautz, Marshall and Blandford, Roger and Brenneman, Laura and Brown, Gregory V and Bulbul, Esra and Cackett, Edward and Chernyakova, Maria and Chiao, Meng and Coppi, Paolo and Costantini, Elisa and De Plaa, Jelle and Den Herder, Jan-Willem and Done, Chris and Dotani, Tadayasu and Ebisawa, Ken and Eckart, Megan and Enoto, Teruaki and Ezoe, Yuichiro and Fabian, Andrew C and Ferrigno, Carlo and Foster, Adam and Fujimoto, Ryuichi and Fukazawa, Yasushi and Furuzawa, Akihiro and Galeazzi, Massimiliano and Gallo, Luigi and Gandhi, Poshak and Giustini, Margherita and Goldwurm, Andrea and Gu, Liyi and Guainazzi, Matteo and Haba, Yoshito and Hagino, Kouichi and Hamaguchi, Kenji and Harrus, Ilana and Hatsukade, Isamu and Hayashi, Katsuhiro and Hayashi, Takayuki and Hayashida, Kiyoshi and Hiraga, Junko and Hornschemeier, Ann and Hoshino, Akio and Hughes, John and Iizuka, Ryo and Inoue, Hajime and Inoue, Yoshiyuki and Ishibashi, Kazunori and Ishida, Manabu and Ishikawa, Kumi and Ishisaki, Yoshitaka and Itoh, Masayuki and Iyomoto, Naoko and Kaastra, Jelle and Kallman, Timothy and Kamae, Tuneyoshi and Kara, Erin and Kataoka, Jun and Katsuda, Satoru and Katsuta, Junichiro and Kawaharada, Madoka and Kawai, Nobuyuki and Kelley, Richard and Khangulyan, Dmitry and Kilbourne, Caroline and King, Ashley and Kitaguchi, Takao and Kitamoto, Shunji and Kitayama, Tetsu and Kohmura, Takayoshi and Kokubun, Motohide and Koyama, Shu and Koyama, Katsuji and Kretschmar, Peter and Krimm, Hans and Kubota, Aya and Kunieda, Hideyo and Laurent, Philippe and Lebrun, François and Lee, Shiu-Hang and Leutenegger, Maurice and Limousin, Olivier and Loewenstein, Michael and Long, Knox S and Lumb, David and Madejski, Grzegorz and Maeda, Yoshitomo and Maier, Daniel and Makishima, Kazuo and Markevitch, Maxim and ... and Hitomi Collaboration and SLAC National Accelerator Lab., Menlo Park, CA (United States)
Nature, ISSN 0028-0836, 07/2016, Volume 535, Issue 7610, pp. 117 - 121
Clusters of galaxies are the most massive gravitationally bound objects in the Universe and are still forming. They are thus important probes(1) of... 
NGC 1275 | GALAXY CLUSTERS | TURBULENT VELOCITY | MULTIDISCIPLINARY SCIENCES | LINE | GAS | NGC-1275 | CONSTRAINTS | X-RAY SPECTROSCOPY | XMM-NEWTON | FEEDBACK | Clusters | Observations | Stars | Cosmology | Astrophysics | Velocity | Stars & galaxies | ASTRONOMY AND ASTROPHYSICS | GRQC | ASTRO
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3. Full Text Frequent inactivation of A20 in B-cell lymphomas
by Kato, Motohiro and Sanada, Masashi and Kato, Itaru and Sato, Yasuharu and Takita, Junko and Takeuchi, Kengo and Niwa, Akira and Chen, Yuyan and Nakazaki, Kumi and Nomoto, Junko and Asakura, Yoshitaka and Muto, Satsuki and Tamura, Azusa and Iio, Mitsuru and Akatsuka, Yoshiki and Hayashi, Yasuhide and Mori, Hiraku and Igarashi, Takashi and Kurokawa, Mineo and Chiba, Shigeru and Mori, Shigeo and Ishikawa, Yuichi and Okamoto, Koji and Tobinai, Kensei and Nakagama, Hitoshi and Nakahata, Tatsutoshi and Yoshino, Tadashi and Kobayashi, Yukio and Ogawa, Seishi
Nature, ISSN 0028-0836, 06/2009, Volume 459, Issue 7247, pp. 712 - 716
A20 is a negative regulator of the NF-kappa B pathway and was initially identified as being rapidly induced after tumour-necrosis factor-alpha stimulation(1).... 
SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACTIVATION | GENE | MULTIDISCIPLINARY SCIENCES | NECROSIS FACTOR-ALPHA | ZINC-FINGER PROTEIN | TNFAIP3 | CLASSICAL HODGKIN LYMPHOMA | INHIBITOR | NF-KAPPA-B | EPSTEIN-BARR-VIRUS | Cell Line | Gene Expression | Humans | Gene Silencing | Genome - genetics | NF-kappa B - metabolism | Nuclear Proteins - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Lymphoma, B-Cell - genetics | Animals | Cysteine Endopeptidases - metabolism | NF-kappa B - genetics | Cysteine Endopeptidases - genetics | Lymphoma, B-Cell - physiopathology | Tumor Necrosis Factor alpha-Induced Protein 3 | Mice | Apoptosis - physiology | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | DNA-Binding Proteins | Causes of | Genetic aspects | B cells | Lymphocytic leukemia | Abnormalities | Proteins | Lymphomas | Histology | Mutation | Cells | Cancer | Apoptosis | Calcium phosphates
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4. Full Text Grinding and chemical mechanical polishing process for micropore x-ray optics fabricated with deep reactive ion etching
by Fukushima, Aoto and Fujitani, Maiko and Ishikawa, Kumi and Numazawa, Masaki and Ishi, Daiki and Otsubo, Ryota and Nagatoshi, Hikaru and Suzuki, Hikaru and Yuasa, Tatsuya and Ohashi, Takaya and Mitsuda, Kazuhisa and Ezoe, Yuichiro
Applied optics, ISSN 1559-128X, 07/2019, Volume 58, Issue 19, p. 5240
Silicon micropore optics using deep reactive ion etching of silicon wafers has been being developed for future x-ray astronomy missions. Sidewalls of the... 
Mechanical polishing | Angular resolution | Silicon wafers | Etching | Chemical-mechanical polishing | X ray optics | Grinding | X ray mirrors | Thickness | Organic chemistry | Ion etching | Micrometers | Reactive ion etching | Space missions | Cleanrooms | Silicon | Angle of reflection | X ray astronomy | Reflectance
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5. Full Text Pt thermal atomic layer deposition for silicon x-ray micropore optics
by Takeuchi, Kazuma and Ezoe, Yuichiro and Ishikawa, Kumi and Numazawa, Masaki and Terada, Masaru and Ishi, Daiki and Fujitani, Maiko and Sowa, Mark J and Ohashi, Takaya and Mitsuda, Kazuhisa
Applied Optics, ISSN 1559-128X, 04/2018, Volume 57, Issue 12, pp. 3237 - 3243
We fabricated a silicon micropore optic using deep reactive ion etching and coated by Pt with atomic layer deposition (ALD). We confirmed that a metal/metal... 
PLATINUM | ALD | FILMS | OPTICS | REMOTE PLASMA | K alpha line | Ion etching | Atomic force microscopy | Annealing | Reactive ion etching | Angular resolution | Atomic layer deposition | Silicon | Surface roughness | Microscopes | Aluminum oxide
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6. Full Text Consumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice
by Ohsawa, Ikuroh and Nishimaki, Kiyomi and Yamagata, Kumi and Ishikawa, Masahiro and Ohta, Shigeo
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 12/2008, Volume 377, Issue 4, pp. 1195 - 1198
Oxidative stress is implicated in atherogenesis; however most clinical trials with dietary antioxidants failed to show marked success in preventing... 
Lifestyle-related disease | Molecular hydrogen | Atherogenesis | Oxidative stress | Arteriosclerosis | ApoE | Dihydrogen | Preventive medicine | Antioxidant | Macrophage | VITAMIN-E | ANTIOXIDANTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INHALATION | INJURY | RAT MODEL | SUPPLEMENTATION | BIOPHYSICS | INCREASE | IN-VIVO | APOE-DEFICIENT MICE | Atherosclerosis - pathology | Antioxidants - chemistry | Oxidative Stress | Atherosclerosis - genetics | Drinking | Hydrogen - chemistry | Mice, Knockout | Aorta - pathology | Animals | Apolipoproteins E - genetics | Antioxidants - administration & dosage | Water - chemistry | Water - administration & dosage | Hydrogen - administration & dosage | Mice | Atherosclerosis - prevention & control | Disease Models, Animal | Antioxidants | Prevention | Medical colleges | Active oxygen | Analysis | Atherosclerosis | Consumption data | Apolipoproteins | Macrophages
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7. Full Text Mouthguard Controller for Unconstrained Controlling of External Devices
by Toma, Koji and Tomoto, Keisuke and Yokota, Kumi and Yasuda, Nao and Ishikawa, Tatsuya and Arakawa, Takahiro and Mitsubayashi, Kohji
Sensors and Materials, ISSN 0914-4935, 12/2018, Volume 30, Issue 12, p. 3053
A mouthguard (MG) controller with a wireless data transmitter was developed for unconstrained control of external devices. The MG controller was composed of... 
Pressure sensors | Occlusion | Bluetooth | Dental materials | Algorithms | Response time | External pressure | Sensors | Mouthguards
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8. Full Text Intracoronary administration of nicorandil during primary percutaneous coronary intervention: Impact on restoration of regional myocardial perfusion in reperfused myocardium during the subacute phase of myocardial infarction
by Takabatake, Wataru and Noma, Takahisa and Iwado, Yasuyoshi and Ishikawa, Kaori and Ishikawa, Shohei and Tobiume, Atsushi and Hasui, Yusuke and Matsunaga, Keiji and Mantani, Kaoru and Konishi, Kumi and Kawakami, Ryo and Ishihara, Naoko and Ishihara, Yasuhiro and Ishizawa, Makoto and Murakami, Kazushi and Ohmori, Koji and Nishiyama, Yoshihiro and Kohno, Masakazu
IJC Heart & Vasculature, ISSN 2352-9067, 09/2015, Volume 8, Issue C, pp. 81 - 86
The impact of nicorandil as adjunctive therapy for percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI) is... 
Myocardial infarction | Myocardial blood flow | Nicorandil | Positron emission tomography
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9. Full Text Multi-professional meetings on health checks and communication in providing nutritional guidance for infants and toddlers in Japan: a cross-sectional, national survey-based study
by Ishikawa, Midori and Ishikawa, Midori and Eto, Kumi and Eto, Kumi and Haraikawa, Mayu and Haraikawa, Mayu and Sasaki, Kemal and Sasaki, Kemal and Yamagata, Zentaro and Yamagata, Zentaro and Yokoyama, Tetsuji and Yokoyama, Tetsuji and Kato, Noriko and Kato, Noriko and Morinaga, Yumiko and Morinaga, Yumiko and Yamazaki, Yoshihisa and Yamazaki, Yoshihisa
BMC pediatrics, ISSN 1471-2431, 10/2018, Volume 18, Issue 1, pp. 325 - 9
BackgroundHealth personnel must provide continuous support in response to problematic results from health checks of infants and toddlers (hereinafter... 
Infant health checks | Community collaboration | Nutritional guidance | Multi-professional meeting | Japan | COLLABORATION | PEDIATRICS | PROGRAM | CHILDREN | Communication in medicine | Conferences, meetings and seminars | Nutrition | Analysis | Infants | Product/Service Evaluations | Medical screening | Food and nutrition | Pediatric research | Health aspects | Studies | Preschool children | Collaboration
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10. Full Text Release of phosphorylated HSP27 (HSPB1) from platelets is accompanied with the acceleration of aggregation in diabetic patients
by Tokuda, Haruhiko and Kuroyanagi, Gen and Tsujimoto, Masanori and Enomoto, Yukiko and Matsushima-Nishiwaki, Rie and Onuma, Takashi and Kojima, Akiko and Doi, Tomoaki and Tanabe, Kumiko and Akamatsu, Shigeru and Iida, Hiroki and Ogura, Shinji and Otsuka, Takanobu and Iwama, Toru and Tanikawa, Takahisa and Ishikawa, Kei and Kojima, Kumi and Kozawa, Osamu
PLoS ONE, ISSN 1932-6203, 06/2015, Volume 10, Issue 6, p. e0128977
We investigated the relationship between HSP27 phosphorylation and collagen-stimulated activation of platelets in patients with diabetes mellitus (DM).... 
HEAT-SHOCK PROTEINS | ACTIVATION | COLLAGEN | MAP KINASE | MULTIDISCIPLINARY SCIENCES | CARDIOVASCULAR-DISEASE | ALPHA-B-CRYSTALLIN | RECEPTOR | MECHANISMS | HEAT-SHOCK-PROTEIN-27 | CELL-DEATH | Diabetics | Care and treatment | Platelet-derived growth factor | Collagen | Heat shock proteins | Hostages | Diabetes | Enzyme-linked immunosorbent assay | Phosphorylation | Laboratories | Collagens | Critical care | Cardiovascular disease | Agglomeration | Neurosurgery | Kinases | Bone surgery | Western blotting | Pain | University graduates | Recombinant | Diabetes mellitus | Adenosine diphosphate | Pharmacology | Platelet aggregation | Patients | Medicine | Gerontology | Hsp27 protein | Orthopedics | Anesthesiology | Acceleration | Platelets | Apoptosis | Geriatrics
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11. Full Text Activity of EGFR-tyrosine kinase and ALK inhibitors for EML4-ALK-rearranged non-small-cell lung cancer harbored coexisting EGFR mutation
by Miyanaga, Akihiko and Shimizu, Kumi and Noro, Rintaro and Seike, Masahiro and Kitamura, Kazuhiro and Kosaihira, Seiji and Minegishi, Yuji and Shukuya, Takehito and Yoshimura, Akinobu and Kawamoto, Masashi and Tsuchiya, Shinichi and Hagiwara, Koichi and Soda, Manabu and Takeuchi, Kengo and Yamamoto, Nobuyuki and Mano, Hiroyuki and Ishikawa, Yuichi and Gemma, Akihiko
BMC Cancer, ISSN 1471-2407, 05/2013, Volume 13, p. 262
Background: The EML4-ALK (echinoderm microtubule-associated protein-like 4 gene and the anaplastic lymphoma kinase gene) fusion oncogene represents a novel... 
EGFR mutation | EML4-ALK | Lung cancer | TRANSCRIPTS | GEFITINIB | ONCOLOGY | ADENOCARCINOMA | EML4-ALK FUSION GENE | Carcinoma, Non-Small-Cell Lung - pathology | Immunohistochemistry | Lung Neoplasms - genetics | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Humans | Middle Aged | Molecular Sequence Data | Lung Neoplasms - pathology | Genes, erbB-1 | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Oncogene Proteins, Fusion - genetics | Protein Kinase Inhibitors - therapeutic use | Base Sequence | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Female | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | Lung cancer, Non-small cell | Genetic aspects | Enzyme inhibitors
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12. Full Text Perifollicular elastolysis with atopic dermatitis
by Amano, Hiroo and Kishi, Chikako and Motegi, Sei‐ichiro and Aoyama, Kumi and Shimizu, Akira and Ishikawa, Osamu
The Journal of Dermatology, ISSN 0385-2407, 03/2014, Volume 41, Issue 3, pp. 231 - 232
DERMATOLOGY | Female | Dermatitis, Atopic - pathology | Dermatitis, Atopic - complications | Humans | Middle Aged | Hair Follicle - pathology | Atopic dermatitis
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13. Full Text Disrupting ceramide-CD300f interaction prevents septic peritonitis by stimulating neutrophil recruitment
by Izawa, Kumi and Maehara, Akie and Isobe, Masamichi and Yasuda, Yuka and Urai, Makoto and Hoshino, Yasutaka and Ueno, Keigo and Matsukawa, Toshihiro and Takahashi, Mariko and Kaitani, Ayako and Shiba, Emiko and Takamori, Ayako and Uchida, Shino and Uchida, Koichiro and Maeda, Keiko and Nakano, Nobuhiro and Yamanishi, Yoshinori and Oki, Toshihiko and Voehringer, David and Roers, Axel and Nakae, Susumu and Ishikawa, Junko and Kinjo, Yuki and Shimizu, Toshiaki and Ogawa, Hideoki and Okumura, Ko and Kitamura, Toshio and Kitaura, Jiro
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 4298 - 13
Sepsis is a serious clinical problem. Negative regulation of innate immunity is associated with sepsis progression, but the underlying mechanisms remains... 
MORTALITY | CMRF-35-LIKE MOLECULE-1 | IMMUNOGLOBULIN-LIKE RECEPTORS | MAST-CELL ACTIVATION | FC-EPSILON-RI | CECAL LIGATION | NEGATIVE REGULATION | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | MOUSE | SEPSIS | Chemotactic factors | Animal models | Immune response | Cecum | Neutrophils | Innate immunity | Leukocytes (neutrophilic) | E coli | Rodents | Ceramide | Sepsis | Mast cells | Peritonitis | Cell migration | Peritoneum
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14. Full Text Effects of chronic [gamma]-irradiation on growth and sexual maturation of the Tohoku hynobiid salamander, Hynobius lichenatus
by Fuma, Shoichi and Soeda, Haruhi and Ihara, Sadao and Matsui, Kumi and Kawaguchi, Isao and Ishikawa, Takahiro and Kubota, Yoshihisa and Watanabe, Yoshito and Aono, Tatsuo
Journal of Environmental Radioactivity, ISSN 0265-931X, 01/2019, Volume 196, p. 98
Growth | Radiation | Amphibians
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15. A case of multiple evanescent white dot syndrome with optic disc edema
by Sasaki, Shuuichirou and Suzuki, Eimi and Ishikawa, Nobuyuki and Shirai, Kumi and Saika, Shizuya
Japanese Journal of Clinical Ophthalmology, ISSN 0370-5579, 09/2018, Volume 72, Issue 9, pp. 1257 - 1262
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16. Full Text Evaluation of alignment error of micropore X-ray optics caused by hot plastic deformation
by Numazawa, Masaki and Ishi, Daiki and Ezoe, Yuichiro and Takeuchi, Kazuma and Terada, Masaru and Fujitani, Maiko and Ishikawa, Kumi and Nakajima, Kazuo and Morishita, Kohei and Ohashi, Takaya and Mitsuda, Kazuhisa and Nakamura, Kasumi and Noda, Yusuke
Japanese Journal of Applied Physics, ISSN 0021-4922, 06/2018, Volume 57, Issue 6, p. 6
We report on the evaluation and characterization of micro-electromechanical system (MEMS) X-ray optics produced by silicon dry etching and hot plastic... 
PHYSICS, APPLIED | PERFORMANCE | Silicon wafers | Angular resolution | Deformation mechanisms | Etching | Plastic deformation | X ray optics | K alpha line | Errors | Alignment | X rays | Packaging industry | Silicon | Pencil beams
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