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1. Full Text Intravascular-catheter-related infections
by Raad, Issam
The Lancet, ISSN 0140-6736, 1998, Volume 351, Issue 9106, pp. 893 - 898
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/S0140-6736(97)10006-X Byline: Issam Raad (a) Author Affiliation: (a)... 
MEDICINE, GENERAL & INTERNAL | BARRIER PRECAUTIONS | CONTROLLED TRIAL | IMMUNOCOMPROMISED PATIENTS | PROSPECTIVE RANDOMIZED MULTICENTER | CRITICALLY ILL | PREVENTION | STAPHYLOCOCCUS-AUREUS BACTEREMIA | SEPSIS | CENTRAL VENOUS CATHETERS | ENDOLUMINAL BRUSH | Bacteremia - microbiology | Bacterial Adhesion | Bacterial Infections - prevention & control | Biofilms | Candidiasis - etiology | Catheterization - methods | Bacterial Infections - etiology | Humans | Catheters, Indwelling - adverse effects | Catheterization, Central Venous - adverse effects | Staphylococcal Infections - etiology | Prevention | Causes of | Nosocomial infections | Complications | Septicemia | Intravenous catheterization | Blood vessels | Infections | Catheters
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2. Full Text Intravascular catheter-related infections: advances in diagnosis, prevention, and management
by Raad, Issam, Prof and Hanna, Hend, MD and Maki, Dennis, MD
Lancet Infectious Diseases, The, ISSN 1473-3099, 2007, Volume 7, Issue 10, pp. 645 - 657
Summary Indwelling vascular catheters are a leading source of bloodstream infections in critically ill patients and cancer patients. Because clinical... 
Infectious Disease | ANTISEPTIC-IMPREGNATED CATHETER | INFECTIOUS DISEASES | BLOOD-STREAM INFECTION | PROSPECTIVE RANDOMIZED-TRIAL | INTENSIVE-CARE-UNIT | SILVER-SULFADIAZINE | STAPHYLOCOCCUS-AUREUS BACTEREMIA | CENTRAL-VENOUS-CATHETER | STERILE BARRIER PRECAUTIONS | CRITICALLY-ILL PATIENTS | RAPID DIAGNOSIS | Catheters, Indwelling - classification | Humans | Bacteremia - drug therapy | Anti-Infective Agents - therapeutic use | Bacteremia - diagnosis | Fungemia - prevention & control | Fungemia - diagnosis | Anti-Infective Agents - administration & dosage | Bacteremia - prevention & control | Fungemia - drug therapy | Catheters, Indwelling - adverse effects | Catheterization, Central Venous - adverse effects | Catheterization, Peripheral - adverse effects | Medical equipment | Health aspects | Physiological apparatus
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3. Full Text The changing epidemiology of invasive candidiasis: Candida glabrata and candida krusei as the leading causes of candidemia in hematologic malignancy
by Hachem, Ray and Hanna, Hend and Kontoyiannis, Dimitrios and Jiang, Ying and Raad, Issam
Cancer, ISSN 0008-543X, 06/2008, Volume 112, Issue 11, pp. 2493 - 2499
BACKGROUND. The objective of the current retrospective study was to compare the epidemiology of candidemia and its risk factors in patients who had hematologic... 
Cancer patient | Hematologic malignancies | Candidemia | Solid tumors | Epidemiology | RISK-FACTORS | SECULAR TRENDS | ANTIFUNGAL SUSCEPTIBILITY | HOSPITAL-ACQUIRED CANDIDEMIA | candidemia | solid tumors | ATTRIBUTABLE MORTALITY | FUNGAL-INFECTIONS | hematologic malignancies | epidemiology | TORULOPSIS-GLABRATA | IMMUNOCOMPROMISED PATIENTS | ONCOLOGY | INTENSIVE-CARE-UNIT | cancer patient | BLOOD-STREAM INFECTIONS | Hematologic Neoplasms - microbiology | Humans | Middle Aged | Risk Factors | Candidiasis - epidemiology | Male | Hematologic Neoplasms - epidemiology | Candidiasis - microbiology | Fungemia - microbiology | Fluconazole - therapeutic use | Antifungal Agents - therapeutic use | Neutropenia - etiology | Candida - classification | Candida - pathogenicity | Candidiasis - drug therapy | Fungemia - drug therapy | Hematologic Neoplasms - drug therapy | Female | Retrospective Studies | Fungemia - epidemiology | Amphotericin B - therapeutic use | Drug Resistance, Fungal | Catheterization, Central Venous - adverse effects | Cohort Studies | Complications and side effects | Candidiasis | Causes of | Research | Blood diseases | Risk factors
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4. Full Text Clinical Practice Guidelines for the Diagnosis and Management of Intravascular Catheter-Related Infection: 2009 Update by the Infectious Diseases Society of America
by Leonard A. Mermel and Michael Allon and Emilio Bouza and Donald E. Craven and Patricia Flynn and Naomi P. O'Grady and Issam I. Raad and Bart J. A. Rijnders and Robert J. Sherertz and David K. Warren
Clinical Infectious Diseases, ISSN 1058-4838, 7/2009, Volume 49, Issue 1, pp. 1 - 45
These updated guidelines replace the previous management guidelines published in 2001. The guidelines are intended for use by health care providers who care... 
Recommendations | Antibiotics | Antimicrobials | Endocarditis | IDSA Guidelines | Infections | Dialysis | Catheters | Blood | Bacteremia | Staphylococcus | INFECTIOUS DISEASES | BLOOD-STREAM INFECTION | RISK-FACTORS | MICROBIOLOGY | STAPHYLOCOCCUS-AUREUS BACTEREMIA | IMMUNOLOGY | ANTIBIOTIC LOCK TECHNIQUE | LIPOSOMAL AMPHOTERICIN-B | GRAM-NEGATIVE BACTEREMIA | CENTRAL VENOUS CATHETERS | CRITICALLY-ILL PATIENTS | IN-VITRO ACTIVITY | SERRATIA-MARCESCENS BACTEREMIA | Case Management | United States | Humans | Cross Infection - diagnosis | Catheter-Related Infections - diagnosis | Cross Infection - drug therapy | Catheter-Related Infections - drug therapy | Infection | Complications and side effects | Blood-borne diseases | Practice guidelines (Medicine) | Reports | Diagnosis | Intravenous catheterization
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5. Full Text Isavuconazole versus voriconazole for primary treatment of invasive mould disease caused by Aspergillus and other filamentous fungi (SECURE): a phase 3, randomised-controlled, non-inferiority trial
by Maertens, Johan A, Prof and Raad, Issam I, Prof and Marr, Kieren A, Prof and Patterson, Thomas F, Prof and Kontoyiannis, Dimitrios P, Prof and Cornely, Oliver A, Prof and Bow, Eric J, Prof and Rahav, Galia, Prof and Neofytos, Dionysios, MD and Aoun, Mickael, MD and Baddley, John W, Prof and Giladi, Michael, MD and Heinz, Werner J, MD and Herbrecht, Raoul, Prof and Hope, William, Prof and Karthaus, Meinolf, Prof and Lee, Dong-Gun, Prof and Lortholary, Olivier, Prof and Morrison, Vicki A, Prof and Oren, Ilana, MD and Selleslag, Dominik, MD and Shoham, Shmuel, MD and Thompson, George R, MD and Lee, Misun, PhD and Maher, Rochelle M, MS and Schmitt-Hoffmann, Anne-Hortense, PhD and Zeiher, Bernhardt, MD and Ullmann, Andrew J, Prof
Lancet, The, ISSN 0140-6736, 2016, Volume 387, Issue 10020, pp. 760 - 769
Summary Background Isavuconazole is a novel triazole with broad-spectrum antifungal activity. The SECURE trial assessed efficacy and safety of isavuconazole... 
Internal Medicine | MYCOSES STUDY-GROUP | MEDICINE, GENERAL & INTERNAL | INFECTIONS | THERAPY | PULMONARY ASPERGILLOSIS | PHARMACODYNAMIC TARGET DETERMINATION | CELL TRANSPLANT PATIENTS | EUROPEAN-ORGANIZATION | CLINICAL-PRACTICE | CANCER | LIPOSOMAL AMPHOTERICIN-B | Triazoles - administration & dosage | Triazoles - adverse effects | Antifungal Agents - adverse effects | Injections, Intravenous | Humans | Middle Aged | Male | Antifungal Agents - therapeutic use | Nitriles - administration & dosage | Pyridines - adverse effects | Voriconazole - administration & dosage | Aspergillosis - mortality | Adult | Female | Aspergillosis - drug therapy | Pyridines - therapeutic use | Triazoles - therapeutic use | Pyridines - administration & dosage | Double-Blind Method | Drug Administration Schedule | Voriconazole - adverse effects | Administration, Oral | Voriconazole - therapeutic use | Treatment Outcome | Mycoses - drug therapy | Aged | Mycoses - mortality | Nitriles - adverse effects | Antifungal Agents - administration & dosage | Nitriles - therapeutic use | Mycoses | Clinical trials | Care and treatment | Molds (Fungi) | Studies | Fungi | Transplants & implants | Hematology | Mortality | Fungal infections | Drug therapy
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6. Biofilm-based central line-associated bloodstream infections
by Yousif, Ammar and Jamal, Mohamed A and Raad, Issam
Advances in Experimental Medicine and Biology, ISSN 0065-2598, 2015, Volume 830, pp. 157 - 179
Different types of central venous catheters (CVCs) have been used in clinical practice to improve the quality of life of chronically and critically ill... 
INFECTIOUS DISEASES | FIBRONECTIN-BINDING PROTEINS | ESCHERICHIA-COLI BIOFILMS | CANDIDA-ALBICANS | MIXED-SPECIES BIOFILMS | MICROBIOLOGY | STAPHYLOCOCCUS-AUREUS ADHESION | MUCOID PSEUDOMONAS-AERUGINOSA | ANTIBIOTIC-IMPREGNATED CATHETERS | CENTRAL VENOUS CATHETERS | CRITICALLY-ILL PATIENTS | EDTA LOCK SOLUTION | Microbial Consortia - physiology | Catheter-Related Infections - etiology | Humans | Biofilms - growth & development | Catheterization, Central Venous - methods | Microscopy, Electron | Candida - classification | Catheter-Related Infections - blood | Catheter-Related Infections - microbiology | Catheters, Indwelling - adverse effects | Bacteria - classification | Bacteria - ultrastructure | Catheterization, Central Venous - adverse effects | Candida - ultrastructure
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7. Full Text Executive Summary: Clinical Practice Guideline for the Use of Antimicrobial Agents in Neutropenic Patients with Cancer: 2010 Update by the Infectious Diseases Society of America
by Alison G. Freifeld and Eric J. Bow and Kent A. Sepkowitz and Michael J. Boeckh and James I. Ito and Craig A. Mullen and Issam I. Raad and Kenneth V. Rolston and Jo-Anne H. Young and John R. Wingard
Clinical Infectious Diseases, ISSN 1058-4838, 2/2011, Volume 52, Issue 4, pp. 427 - 431
This document updates and expands the initial Infectious Diseases Society of America (IDSA) Fever and Neutropenia Guideline that was published in 1997 and... 
Recommendations | Antifungals | IDSA GUIDELINES | Infectious diseases | Antibiotics | Antimicrobials | Infections | Fever | Symptoms | Neutropenia | Cancer | INFECTIOUS DISEASES | MICROBIOLOGY | IMMUNOLOGY
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8. Full Text Making catheter-related bloodstream infections history: From the slogan to the serious strategy
by Raad, Issam
Critical Care Medicine, ISSN 0090-3493, 02/2009, Volume 37, Issue 2, pp. 789 - 791
Anti-infective central venous catheters | Critically ill patients | Catheter-related bloodstream infection | catheter-related bloodstream infection | TRIAL | critically ill patients | PREVENTION | DECREASE | CHLORHEXIDINE | anti-infective central venous catheters | CENTRAL VENOUS CATHETERS | CRITICAL CARE MEDICINE | Sepsis - etiology | Clinical Trials as Topic | Catheter-Related Infections - complications | Humans | Catheter-Related Infections - prevention & control
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9. Full Text Advances in prevention and management of central line-associated bloodstream infections in patients with cancer
by Raad, Issam and Raad, Issam and Chaftari, Anne-Marie and Chaftari, Anne-Marie
Clinical Infectious Diseases, ISSN 1058-4838, 2014, Volume 59, Issue suppl_5, pp. S340 - S343
Central lines, which are essential for treating cancer, are associated with at least 400 000 episodes of bloodstream infection in patients with cancer every... 
central line–associated bloodstream infections | central venous catheters | prevention and management | Central line-associated bloodstream infections | catheter-related infections | cancer patients | INFECTIOUS DISEASES | NEGATIVE BACILLI | MINOCYCLINE-EDTA | central line-associated bloodstream infections | MICROBIOLOGY | RANDOMIZED CONTROLLED-TRIAL | IMMUNOLOGY | CHILDREN | REMOVAL | LOCK SOLUTION | BACTEREMIA | HEMODIALYSIS | Bacteremia - microbiology | Anti-Bacterial Agents - therapeutic use | Neoplasms - complications | Bacteremia - prevention & control | Humans | Bacteremia - drug therapy | Bacteremia - etiology | Catheterization, Central Venous - adverse effects
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10. Full Text Using procalcitonin-guided algorithms to improve antimicrobial therapy in ICU patients with respiratory infections and sepsis
by Schuetz, Philipp and Raad, Issam and Amin, Devendra N
Current Opinion in Critical Care, ISSN 1070-5295, 10/2013, Volume 19, Issue 5, pp. 453 - 460
Purpose of reviewIn patients with systemic bacterial infections hospitalized in ICUs, the inflammatory biomarker procalcitonin (PCT) has been shown to aid... 
Serial measurement | Antibiotic stewardship | Procalcitonin | Intensive care unit | C-REACTIVE PROTEIN | COMMUNITY-ACQUIRED PNEUMONIA | GENE-RELATED PEPTIDE | INTENSIVE-CARE PATIENTS | serial measurement | procalcitonin | antibiotic stewardship | SEPTIC SHOCK | intensive care unit | INTERNATIONAL GUIDELINES | ANTIBIOTIC-TREATMENT | SERUM PROCALCITONIN | CRITICALLY-ILL PATIENTS | DURATION | CRITICAL CARE MEDICINE | Calcitonin Gene-Related Peptide | Critical Care - methods | Decision Making | Calcitonin - blood | Diagnosis, Differential | Intensive Care Units | Protein Precursors - blood | Bacterial Infections - drug therapy | Humans | Biomarkers - blood | Bacterial Infections - blood | Bacterial Infections - diagnosis | Anti-Bacterial Agents - administration & dosage
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11. Full Text Comparative Activities of Daptomycin, Linezolid, and Tigecycline against Catheter-Related Methicillin-Resistant Staphylococcus Bacteremic Isolates Embedded in Biofilm
by Issam Raad and Hend Hanna and Ying Jiang and Tanya Dvorak and Ruth Reitzel and Gassan Chaiban and Robert Sherertz and Ray Hachem
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 05/2007, Volume 51, Issue 5, pp. 1656 - 1660
Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
IN-VITRO | MINOCYCLINE | ANTIBIOTICS | INFECTIONS | VANCOMYCIN | VIVO ACTIVITIES | HEMODIALYSIS | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | AUREUS | CENTRAL VENOUS CATHETERS | ANTIMICROBIAL LOCK THERAPY | Linezolid | Minocycline - pharmacology | Humans | Minocycline - analogs & derivatives | Acetamides - pharmacology | Bacteremia - microbiology | Daptomycin - pharmacology | Biofilms | Oxazolidinones - pharmacology | Anti-Bacterial Agents - pharmacology | Methicillin Resistance | Staphylococcus aureus - drug effects | Catheterization, Central Venous - adverse effects | Experimental Therapeutics
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