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Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1125 - 15
To ensure successful plant reproduction and crop production, the spatial and temporal control of the termination of the floral meristem must be coordinated. In... 
FLOWER DEVELOPMENT | ARABIDOPSIS-THALIANA | POLYCOMB GROUP PROTEINS | QUIESCENT CENTER | CARPEL DEVELOPMENT | MULTIDISCIPLINARY SCIENCES | MERISTEM TERMINATION | ZINC-FINGER | GENE-EXPRESSION | APICAL MERISTEMS | CRABS-CLAW | Gene silencing | Repressing | Crustaceans | Control | Crop production | Crabs | Agricultural production | Spatial discrimination | Stem cells | Homeostasis | Maxima | Tuning
Journal Article
Nature, ISSN 0028-0836, 05/2010, Volume 465, Issue 7295, pp. 223 - 226
Amyotrophic lateral sclerosis (ALS) has its onset in middle age and is a progressive disorder characterized by degeneration of motor neurons of the primary... 
OPEN-ANGLE GLAUCOMA | COMPLEX | PROTEIN | GENE | MULTIDISCIPLINARY SCIENCES | EXPRESSION | NEMO | MYOSIN-VI | Amyotrophic Lateral Sclerosis - physiopathology | Humans | Middle Aged | Transcription Factor TFIIIA - genetics | Cytoplasm - metabolism | Male | NF-kappa B - metabolism | Cytoplasm - pathology | Transcription Factor TFIIIA - metabolism | Mutation, Missense - genetics | DNA-Binding Proteins - metabolism | Young Adult | Base Sequence | Aged, 80 and over | Adult | Female | Child | Superoxide Dismutase - metabolism | NF-kappa B - agonists | Amino Acid Sequence | NF-kappa B - antagonists & inhibitors | Amyotrophic Lateral Sclerosis - genetics | Japan | Mutant Proteins - genetics | Transcription Factor TFIIIA - chemistry | Exons - genetics | Mutant Proteins - metabolism | Mutation - genetics | Transcription Factor TFIIIA - analysis | Protein Transport | Amyotrophic Lateral Sclerosis - pathology | Asian Continental Ancestry Group | Pedigree | Mutant Proteins - chemistry | Adolescent | Amyotrophic Lateral Sclerosis - metabolism | Polymorphism, Single Nucleotide - genetics | Aged | Consanguinity | Superoxide Dismutase-1 | Mutant Proteins - analysis | Codon, Nonsense - genetics | Sequence Deletion - genetics | Cellular proteins | Gene mutations | Physiological aspects | Amyotrophic lateral sclerosis | Genetic aspects | Research | Health aspects | Risk factors | Haplotypes | Studies | Genes | Genetics | Amino acids | Mutation | Family medical history | Chromosomes | Apoptosis
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 02/2018, Volume 20, Issue 2, pp. 438 - 442
This study aimed to assess the effect of luseogliflozin on liver fat deposition and compare luseogliflozin to metformin in type 2 diabetes (T2D) patients with... 
antidiabetic drug | SGLT2 inhibitor | fatty liver | GLUCAGON-SECRETION | TRIAL | EFFICACY | SAFETY | SGLT2 INHIBITOR LUSEOGLIFLOZIN | ENDOCRINOLOGY & METABOLISM | STEATOHEPATITIS | MELLITUS | JAPANESE PATIENTS | Glycated Hemoglobin A - analysis | Liver - pathology | Metformin - therapeutic use | Humans | Middle Aged | Male | Tomography, X-Ray Computed | Diabetes Mellitus, Type 2 - metabolism | Weight Loss - drug effects | Metformin - adverse effects | Non-alcoholic Fatty Liver Disease - complications | Drug Therapy, Combination - adverse effects | Liver - drug effects | Sorbitol - analogs & derivatives | Liver - diagnostic imaging | Ultrasonography | Female | Diabetes Mellitus, Type 2 - complications | Hypoglycemic Agents - therapeutic use | Non-alcoholic Fatty Liver Disease - diagnostic imaging | Adiposity - drug effects | Sodium-Glucose Transporter 2 - metabolism | Liver - metabolism | Non-alcoholic Fatty Liver Disease - metabolism | Non-alcoholic Fatty Liver Disease - drug therapy | Lipotropic Agents - therapeutic use | Diabetes Mellitus, Type 2 - blood | Organ Size - drug effects | Pilot Projects | Lipid Metabolism - drug effects | Membrane Transport Modulators - therapeutic use | Sorbitol - adverse effects | Diabetes Mellitus, Type 2 - drug therapy | Membrane Transport Modulators - adverse effects | Hypoglycemic Agents - adverse effects | Sorbitol - therapeutic use | Type 2 diabetes | Fatty liver | Glycosylated hemoglobin | Hypoglycemic agents | Diagnostic imaging | Comparative analysis | Diabetes therapy | Spleen | Alanine | Liver diseases | Fasting | Diabetes mellitus | Glucose | Body mass index | Computed tomography | Hemoglobin | Alanine transaminase | Diabetes | Metformin | Immunoreactivity | Diabetes mellitus (non-insulin dependent)
Journal Article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1661-6596, 08/2019, Volume 20, Issue 16, p. 4065
Journal Article
Journal Article
Japanese Journal of Clinical Oncology, ISSN 0368-2811, 07/2013, Volume 43, Issue 7, pp. 752 - 755
Journal Article
Nature Communications, ISSN 2041-1723, 04/2016, Volume 7, Issue 1, p. 11391
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 5290 - 15
In flowering plants, the switch from floral stem cell maintenance to gynoecium (female structure) formation is a critical developmental transition for... 
RECRUITMENT | PROTEIN | MULTIDISCIPLINARY SCIENCES | ZINC-FINGER | STEM-CELL MAINTENANCE | GENE-EXPRESSION | ARABIDOPSIS | DIFFERENTIATION | SHOOT | CRABS-CLAW | NEGATIVE REGULATOR | Plants (botany) | Chromatin | Phenotypes | Target recognition | Cell walls | Crabs | Homeostasis | Biosynthesis | Maintenance | Gene expression | Crustaceans | Reproduction | Breeding success | Stem cells | Flowering | Feedforward
Journal Article
ANALYTICAL CHEMISTRY, ISSN 0003-2700, 08/2019, Volume 91, Issue 15, pp. 9631 - 9639
Time-course analysis of single cells is important to characterize heterogeneous activities of individual cells such as the metabolic response to their... 
WAX ESTER FERMENTATION | PLATFORM | SYSTEM | CHEMISTRY, ANALYTICAL | SPECTROSCOPY | TRAP | RELEASE | Fluid dynamics | Glass | Biosynthesis | Background noise | Raman spectroscopy | Metabolic response | Microchannels | Euglena | Polysaccharides | Microscopy | Liquid flow | Photosynthesis | Microfluidics | Low temperature
Journal Article
Plant, Cell & Environment, ISSN 0140-7791, 07/2019, Volume 42, Issue 7, pp. 2198 - 2214
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1830, pp. 93 - 108
Gene editing enables the modification of genetic information in a targeted manner. Clustered Regularly Interspaced Short Palindromic Repeats... 
cis-elements | Plant transcription factors | DNA-binding domain | CRISPR/Cas9 | Arabidopsis | Gene editing
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2014, Volume 124, Issue 8, pp. 3479 - 3488
A wide range of antiviral drugs is currently available; however, drug-resistant viruses have begun to emerge and represent a potential public health risk.... 
CYCLIN-DEPENDENT KINASES | MEDICINE, RESEARCH & EXPERIMENTAL | HERPES-SIMPLEX-VIRUS | IN-VITRO | FACTOR P-TEFB | PROTEIN-KINASE | TRANSCRIPTION | ANTIVIRAL ACTIVITY | HOST | HIV-1 REPLICATION | IDENTIFICATION | Transcription, Genetic - drug effects | Rats, Wistar | Antiviral Agents - toxicity | Pyridines - chemistry | Humans | Drug Resistance, Viral | Host-Pathogen Interactions - drug effects | DNA Viruses - genetics | Herpes Simplex - drug therapy | Herpesvirus 1, Human - physiology | Protein Kinase Inhibitors - chemistry | Piperidines - pharmacology | Antiviral Agents - chemistry | HEK293 Cells | Flavonoids - pharmacology | DNA Viruses - physiology | Cytomegalovirus - physiology | Herpesvirus 2, Human - drug effects | Disease Models, Animal | Virus Replication - drug effects | Antiviral Agents - pharmacology | Acyclovir - pharmacology | Adenoviruses, Human - physiology | Rats | Cyclin-Dependent Kinase 9 - antagonists & inhibitors | Transcriptome - drug effects | Mice, Inbred ICR | Herpesvirus 1, Human - drug effects | Herpes Simplex - virology | Animals | Host-Pathogen Interactions - genetics | Pyridines - toxicity | Herpes Simplex - pathology | Adenoviruses, Human - drug effects | Protein Kinase Inhibitors - toxicity | Herpesvirus 2, Human - physiology | Mice | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | HeLa Cells | DNA Viruses - drug effects | Cytomegalovirus - drug effects | Physiological aspects | Research | DNA viruses | Health aspects | Protein kinases | Medical research | Drug resistance | Kinases | Cell cycle
Journal Article