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1. Counter-current chromatography
: special issue
by Ito, Yoichiro
1991, Volume 538, no. 1., viii, 229
Book
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2. Full Text Golden rules and pitfalls in selecting optimum conditions for high-speed counter-current chromatography
by Ito, Yoichiro
Journal of Chromatography A, ISSN 0021-9673, 2005, Volume 1065, Issue 2, pp. 145 - 168
This paper aims to be an aid to those chemists who are interested in utilizing high-speed counter-current chromatography (HSCCC), which is free of irreversible... 
Retention of stationary phase | Partition coefficient | On-line monitoring | pH-zone-refining counter-current chromatography | High-speed counter-current chromatography | Type-J multilayer coil planet centrifuge | type-J multilayer coil planet centrifuge | CHEMISTRY, ANALYTICAL | LIQUID PARTITION CHROMATOGRAPHY | 2-PHASE SOLVENT SYSTEMS | retention of stationary | BIOCHEMICAL RESEARCH METHODS | partition coefficient | high-speed counter-current chromatography | on-line monitoring | COIL PLANET CENTRIFUGE | SOLID SUPPORT | Countercurrent Distribution - methods | Countercurrent Distribution - instrumentation
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3. Full Text pH-zone-refining counter-current chromatography: Origin, mechanism, procedure and applications
by Ito, Yoichiro
Journal of Chromatography A, ISSN 0021-9673, 01/2013, Volume 1271, Issue 1, pp. 71 - 85
► Comprehensive introduction of pH-zone-refining CCC. ► Guidance on procedure of pH-zone-refining CCC for beginners. ► References of over 70 research articles... 
pH-peak-focusing CCC | pH-zone-refining CCC | Affinity CCC | Preparative separation | Chiral CCC | High-speed counter-current chromatography (HSCCC) | PH-zone-refining CCC | PH-peak-focusing CCC | CHEMISTRY, ANALYTICAL | ACID | BIOCHEMICAL RESEARCH METHODS | LIGAND | QUINOLINE YELLOW | Fluorescent Dyes - chemistry | Models, Chemical | Peptides - chemistry | Stereoisomerism | Fluorescent Dyes - isolation & purification | Alkaloids - isolation & purification | Countercurrent Distribution - methods | Sulfonic Acids - chemistry | Peptides - isolation & purification | Kinetics | Sulfonic Acids - isolation & purification | Alkaloids - chemistry | Hydrogen-Ion Concentration | Chromatography | chromatography (HSCCC) | High-speed counter-current
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4. Countercurrent chromatography
: theory and practice
by Mandava, N. Bhushan and Ito, Yoichiro
1988, ISBN 9780824778156, x, 841
Countercurrent chromatography | Chromatographie à contre-courant
Book
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5. High-speed countercurrent chromatography
by Conway, Walter D and Ito, Yoichiro, 1928
1996, Chemical analysis, ISBN 9780471637493, Volume 132, xxiii, 454
Countercurrent chromatography
Book
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6. pH-zone-refining counter-current chromatography: Origin, mechanism, procedure and applications
by Ito, Yoichiro
Journal of Chromatography A, ISSN 0021-9673, 01/2013, Volume 1271, Issue 1, pp. 71 - 85
Since 1980, high-speed counter-current chromatography (HSCCC) has been used for separation and purification of natural and synthetic products in a standard... 
Analytical chemistry | Elution | Separation | Flowmeters | Boundaries | Borders | Chromatography
Journal Article
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7. pH-zone-refining counter-current chromatography: Origin, mechanism, procedure and applications
by Ito, Yoichiro
Journal of Chromatography A, ISSN 0021-9673, 01/2013, Volume 1271, Issue 1, pp. 71 - 85
Since 1980, high-speed counter-current chromatography (HSCCC) has been used for separation and purification of natural and synthetic products in a standard... 
Journal Article
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8. Full Text Counter-current motion in counter-current chromatography
by Ito, Yoichiro
Journal of Chromatography A, ISSN 0021-9673, 12/2014, Volume 1372, pp. 128 - 132
After the CCC2012 meeting, I have received an e-mail regarding the terminology of “Countercurrent Chromatography”. It stated that the term “Countercurrent” is... 
Centrifugal separations | Countercurrent chromatography | Terminology | Countercurrent | Liquid–liquid separations | Stationary phase | Liquid-liquid separations | CHEMISTRY, ANALYTICAL | BIOCHEMICAL RESEARCH METHODS | COIL PLANET CENTRIFUGE | Terminology as Topic | Motion | Hydrodynamics | Internet | Countercurrent Distribution | Chromatography | Liquid chromatography | Hydrostatics | Separation | Email | Fluid dynamics | Fluid flow | Search engines | centrifugal separations | stationary phase | terminology | liquid-liquid separations | countercurrent
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9. Full Text Overview of the BioBank Japan Project: Study design and profile
by Nagai, Akiko and Hirata, Makoto and Kamatani, Yoichiro and Muto, Kaori and Matsuda, Koichi and Kiyohara, Yutaka and Ninomiya, Toshiharu and Tamakoshi, Akiko and Yamagata, Zentaro and Mushiroda, Taisei and Murakami, Akira and Murakami, Yoshinori and Yuji, Koichiro and Furukawa, Yoichi and Zembutsu, Hitoshi and Tanaka, Toshihiro and Ohnishi, Yozo and Nakamura, Yusuke and Shiono, Masaki and Misumi, Kazuo and Kaieda, Reiji and Harada, Hiromasa and Minami, Shiro and Emi, Mitsuru and Emoto, Naoya and Daida, Hiroyuki and Miyauchi, Katsumi and Asai, Satoshi and Moriyama, Mitsuhiko and Takahashi, Yasuo and Fujioka, Tomoaki and Obara, Wataru and Mori, Seijiro and Ito, Hideki and Nagayama, Satoshi and Miki, Yoshio and Masumoto, Akihide and Yamada, Akira and Nishizawa, Yasuko and Kodama, Ken and Kutsumi, Hiromu and Sugimoto, Yoshihisa and Koretsune, Yukihiro and Kusuoka, Hideo and Yanai, Hideki and Kubo, Michiaki and BioBank Japan Cooperative Hosp Grp and BioBank Japan Cooperative Hospital Group
Journal of Epidemiology, ISSN 0917-5040, 03/2017, Volume 27, Issue 3, pp. S2 - S8
The BioBank Japan (BBJ) Project was launched in 2003 with the aim of providing evidence for the implementation of personalized medicine by constructing a... 
Personalized medicine | Biobank | BioBank Japan Project | Genomic research | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | Biological Specimen Banks | Genetic Research | Humans | Japan | Middle Aged | Female | Male | Registries | Research Design | Precision Medicine | Studies | Medicine | Precision medicine | Men | Patients | Survival | Deoxyribonucleic acid--DNA | Diseases
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10. Full Text A novel foam based separation strategy for extracting minute target impurities
by Sadegh, Shayan and Dasarathy, Dhweeja and Ito, Yoichiro
Journal of Separation Science, ISSN 1615-9306, 06/2019, Volume 42, Issue 12, pp. 2093 - 2099
The purpose of this study was to extract impurities from compounds using a simple separatory bottle to purify target compounds with a foam column and allow for... 
foam separation | high performance liquid chromatography | dry foam | separatory bottle | dye separation | CHEMISTRY, ANALYTICAL | SAPONINS | PURIFICATION | CHROMATOGRAPHY | Surface active agents | Sulfates | High performance liquid chromatography | Methylene blue | Sodium dodecyl sulfate | Dyes | Separation | Impurities | Foaming | Purity | Foaming agents
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11. Full Text Spiral column configuration for protein separation by high-speed countercurrent chromatography
by Ito, Yoichiro
Chemical Engineering & Processing: Process Intensification, ISSN 0255-2701, 2010, Volume 49, Issue 7, pp. 782 - 792
Retention of the stationary phase of aqueous–aqueous polymer phase systems is improved by a spiral column configuration which utilizes the radially acting... 
Countercurrent chromatography | protein separation | Configuration | polymer phase system | Spiral disk assembly | spiral tube assembly | Coil planet centrifuge | Polymer phase system | Protein separation | Spiral tube assembly | ENGINEERING, CHEMICAL | HYDRODYNAMIC BEHAVIOR | ENERGY & FUELS | RESOLUTION | SOLVENT SYSTEMS | Proteins | Plumes (Fluid dynamics) | Liquid chromatography
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12. Full Text Separation using high-speed counter-current chromatography and identification of 1,3-bistriazene, an impurity in the color additive D&C Red No. 17 (Sudan III)
by Weisz, Adrian and Ridge, Clark D and Perez-Gonzalez, Marianita and Ito, Yoichiro
Journal of Chromatography A, ISSN 0021-9673, 06/2019, Volume 1594, p. 120
The present work describes the application of high-speed counter-current chromatography to the preparative separation of a previously unreported impurity in... 
Usage | Safety and security measures | Analysis | High performance liquid chromatography | Food
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13. Full Text Cross-sectional analysis of BioBank Japan clinical data: A large cohort of 200,000 patients with 47 common diseases
by Hirata, Makoto and Kamatani, Yoichiro and Nagai, Akiko and Kiyohara, Yutaka and Ninomiya, Toshiharu and Tamakoshi, Akiko and Yamagata, Zentaro and Kubo, Michiaki and Muto, Kaori and Mushiroda, Taisei and Murakami, Yoshinori and Yuji, Koichiro and Furukawa, Yoichi and Zembutsu, Hitoshi and Tanaka, Toshihiro and Ohnishi, Yozo and Nakamura, Yusuke and Shiono, Masaki and Misumi, Kazuo and Kaieda, Reiji and Harada, Hiromasa and Minami, Shiro and Emi, Mitsuru and Emoto, Naoya and Arai, Hajime and Yamaji, Ken and Hiratsuka, Yoshimune and Asai, Satoshi and Moriyama, Mitsuhiko and Takahashi, Yasuo and Fujioka, Tomoaki and Obara, Wataru and Mori, Seijiro and Ito, Hideki and Nagayama, Satoshi and Miki, Yoshio and Masumoto, Akihide and Yamada, Akira and Nishizawa, Yasuko and Kodama, Ken and Kutsumi, Hiromu and Sugimoto, Yoshihisa and Koretsune, Yukihiro and Kusuoka, Hideo and Yoshiyama, Takashi and Matsuda, Koichi and BioBank Japan Cooperative Hosp Grp and BioBank Japan Cooperative Hospital Group
Journal of Epidemiology, ISSN 0917-5040, 03/2017, Volume 27, Issue 3, pp. S9 - S21
To implement personalized medicine, we established a large-scale patient cohort, BioBank Japan, in 2003. BioBank Japan contains DNA, serum, and clinical... 
Common disease | Family history | Biobank | BioBank Japan Project | Clinical information | Biobank Common disease | CHRONIC HEPATITIS-B | SUSCEPTIBILITY | RECEPTOR | RISK | POLYMORPHISM | FAMILY-HISTORY | REGION | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | GENE | GRAVES-DISEASE | GENOME-WIDE ASSOCIATION | Medical History Taking | Cross-Sectional Studies | Disease - genetics | Humans | Japan | Middle Aged | Databases, Genetic | Male | Biological Specimen Banks | Female | Aged | Cohort Studies | Precision Medicine | Disease | Sex | Family medical history | Body mass index | Precision medicine | Chronic obstructive pulmonary disease | Genetic factors | Cross sections | Age | Deoxyribonucleic acid--DNA | Hypertension | Nutrition | Lung diseases | Drinking | Regression analysis | Patients | Distributing | Esophagus | Medicine | Body mass | Obstructive lung disease | Cardiovascular diseases | Age composition | Metabolic disorders | Smoking | Cancer
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14. Full Text Enhanced cell‐surface display and secretory production of cellulolytic enzymes with Saccharomyces cerevisiae Sed1 signal peptide
by Inokuma, Kentaro and Bamba, Takahiro and Ishii, Jun and Ito, Yoichiro and Hasunuma, Tomohisa and Kondo, Akihiko
Biotechnology and Bioengineering, ISSN 0006-3592, 11/2016, Volume 113, Issue 11, pp. 2358 - 2366
ABSTRACT Recombinant yeast strains displaying aheterologous cellulolytic enzymes on their cell surfaces using a glycosylphosphatidylinositol (GPI) anchoring... 
Pichia pastoris | β‐glucosidase | Saccharomyces cerevisiae | secretion signal sequence | endo‐glucanase | cell surface display | Secretion signal sequence | β-glucosidase | Cell surface display | Endo-glucanase | endo-glucanase | ALPHA-FACTOR | PROTEIN-PRODUCTION | SEQUENCES | CELLULOSIC ETHANOL-PRODUCTION | beta-glucosidase | STATIONARY-PHASE | YEAST | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PICHIA-PASTORIS | HETEROLOGOUS PROTEINS | EXPRESSION | Saccharomyces cerevisiae - physiology | Membrane Glycoproteins - metabolism | Protein Engineering - methods | Saccharomyces cerevisiae Proteins - metabolism | Cell Membrane - metabolism | Recombinant Proteins - genetics | Genetic Enhancement - methods | Recombinant Proteins - biosynthesis | Saccharomyces cerevisiae Proteins - genetics | Cellulase - secretion | Protein Transport - genetics | Membrane Glycoproteins - genetics | Peptides | Enzymes | Genomics | Bioengineering | Proteins | Yeast | Cellular biology | Trichoderma | Genes | Rhizopus | Surface chemistry | Genomes | Saccharomyces | Cell surface | Gene sequencing | Mating | EXG1 protein | Lignocellulose | Glucoamylase | Localization | Anchoring | Cassettes | Recombinant | Ethanol | Secretion | Cell walls | Glucosidase | Biofuels | Trichoderma reesei | Endoglucanase | Rhizopus oryzae | Glycosylphosphatidylinositol | Cellulolytic enzymes | Utilization
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15. Full Text Foam separation of Rhodamine-G and Evans Blue using a simple separatory bottle system
by Dasarathy, Dhweeja and Ito, Yoichiro
Journal of Chromatography A, ISSN 0021-9673, 09/2017, Volume 1517, pp. 215 - 218
A simple separatory glass bottle was used to improve separation effectiveness and cost efficiency while simultaneously creating a simpler system for separating... 
Dye separation | High-speed and cost-effective separation | Dry foam | Foam separation | Separatory bottle | CHEMISTRY, ANALYTICAL | FLOTATION | BIOCHEMICAL RESEARCH METHODS | Rhodamines - isolation & purification | Nitrogen - chemistry | Sodium Dodecyl Sulfate - chemistry | Solvents - chemistry | Surface-Active Agents - chemistry | Evans Blue - isolation & purification | Chemistry Techniques, Analytical - methods | Surface active agents | Sulfates | foam separation | dry foam | high-speed and cost-effective separation | dye separation
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16. Full Text Dectin-1 plays an important role in house dust mite-induced allergic airway inflammation through the activation of CD11b+ dendritic cells
by Ito, Takashi and Hirose, Koichi and Norimoto, Ayako and Tamachi, Tomohiro and Yokota, Masaya and Saku, Aiko and Takatori, Hiroaki and Saijo, Shinobu and Iwakura, Yoichiro and Nakajima, Hiroshi
Journal of Immunology, ISSN 0022-1767, 01/2017, Volume 198, Issue 1, pp. 61 - 70
It is well known that sensitization against fungi is closely associated with severity of asthma. Dectin-1 (gene symbol Clec7a), a C-type lectin receptor,... 
BETA-GLUCAN RECEPTOR | LUNG | SEVERE ASTHMA | CANDIDA-ALBICANS | HOST-DEFENSE | MICE | DIFFERENTIATION | IMMUNOLOGY | T-CELLS | CLUSTER-ANALYSIS | INNATE IMMUNITY | Chemotaxis, Leukocyte | CD11b Antigen - immunology | Enzyme-Linked Immunosorbent Assay | Dendritic Cells - immunology | Mice, Inbred C57BL | Lectins, C-Type - immunology | Hypersensitivity - immunology | Mice, Knockout | Antigens, Dermatophagoides - immunology | Animals | Asthma - immunology | Mice | Real-Time Polymerase Chain Reaction | Disease Models, Animal | Pyroglyphidae - immunology | CC chemokine receptors | Leukocyte migration | Mediastinum | Epithelial cells | Mites | Lymph nodes | Recruitment | Respiratory tract | Fungi | Glucan | Receptors | Cell activation | CD103 antigen | Interleukin 5 | Rodents | Respiratory tract diseases | Lymphatic system | CD11b antigen | Dendritic cells | CCR7 protein | Cell walls | Hypersensitivity | House dust | Inflammation | Interleukin 13 | Gene expression | Chemokine receptors | Interleukin 17 | Asthma | Drainage | Dust | Lungs | Chemokines | Cell migration | Lymph
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17. Full Text Identification of six new genetic loci associated with atrial fibrillation in the Japanese population
by Low, Siew-Kee and Takahashi, Atsushi and Ebana, Yusuke and Ozaki, Kouichi and Christophersen, Ingrid E and Ellinor, Patrick T and Ogishima, Soichi and Yamamoto, Masayuki and Satoh, Mamoru and Sasaki, Makoto and Yamaji, Taiki and Iwasaki, Motoki and Tsugane, Shoichiro and Tanaka, Keitaro and Naito, Mariko and Wakai, Kenji and Tanaka, Hideo and Furukawa, Tetsushi and Kubo, Michiaki and Ito, Kaoru and Kamatani, Yoichiro and Tanaka, Toshihiro and AFGen Consortium
Nature Genetics, ISSN 1061-4036, 06/2017, Volume 49, Issue 6, pp. 953 - 958
Atrial fibrillation is the most common cardiac arrhythmia and leads to stroke. To investigate genetic loci associated with atrial fibrillation in the Japanese... 
HEART | NEBULETTE MUTATIONS | COMMON VARIANTS | SPINOCEREBELLAR ATAXIA | GENETICS & HEREDITY | EARLY-ONSET | NEBULIN | RISK | CHROMOSOME 4Q25 | DILATED CARDIOMYOPATHY | EXPRESSION | Genetic Predisposition to Disease | Basic Helix-Loop-Helix Transcription Factors - genetics | Humans | Middle Aged | Asian Continental Ancestry Group - genetics | Genetic Loci | Atrial Fibrillation - genetics | Chromosomes, Human, Pair 4 | Shal Potassium Channels - genetics | Adult | Aged | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Quantitative trait loci | Genetic susceptibility | Atrial fibrillation | Genetic research | Genetic aspects | Research | Identification and classification | Risk factors | Cardiac arrhythmia | Stroke | Arrhythmia | Pathogenesis | Genes | Genomes | Preventive medicine | Loci | Fibrillation | Electrocardiography | Gene loci | Genetic factors | Axon guidance | Heart diseases
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18. Full Text EVALUATION OF GLOBAL AND REGIONAL RIGHT VENTRICULAR FUNCTION USING THREE DIMENSIONAL SPECKLE TRACKING ECHOCARDIOGRAPHY SPECIALIZED FOR RIGHT VENTRICLE
by Sakata, Konomi and Uesugi, Yoichiro and Isaka, Aoi and Ito, Junnosuke and Minamishima, Toshinori and Furuya, Mitsufumi and Satoh, Touru and Yoshino, Hideaki
Journal of the American College of Cardiology, ISSN 0735-1097, 03/2018, Volume 71, Issue 11, pp. A1615 - A1615
The 3D RV images were obtained and divided into a total 7 RV segments (including three RV inflow, two apical, and two RV outflow), and measured Global RV-Area... 
Heart | Echocardiography | Ventricle | Pulmonary arteries | Regional analysis
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19. Full Text Perforation and Postoperative Bleeding Associated with Endoscopic Submucosal Dissection in Colorectal Tumors: An Analysis of 398 Lesions Treated in Saga, Japan
by Yamamoto, Koji and Shimoda, Ryo and Ogata, Shinichi and Hara, Megumi and Ito, Yoichiro and Tominaga, Naoyuki and Nakayama, Atsushi and Sakata, Yasuhisa and Tsuruoka, Nanae and Iwakiri, Ryuichi and Fujimoto, Kazuma
Internal Medicine, ISSN 0918-2918, 2018, Volume 57, Issue 15, pp. 2115 - 2122
Objective The aim of this study was to clarify the safety of colorectal endoscopic submucosal dissection (ESD) during the era of health insurance coverage... 
serious complications | colorectal cancer | multivariate analysis | clip | Clip | Serious complications | Multivariate analysis | Colorectal cancer | RISK-FACTORS | MANAGEMENT | METAANALYSIS | NEOPLASMS | EFFICACY | TECHNICAL DIFFICULTY | EMR | MEDICINE, GENERAL & INTERNAL | SPREADING TUMORS | MUCOSAL RESECTION | CLINICAL-OUTCOMES | Transfusion | Complications | Perforation | Colorectal carcinoma | Risk analysis | Blood transfusion | Bleeding | Risk factors | Histopathology | Endoscopes | Surgery | Rectum | Clipping | Safety | Endoscopy | Lesions | Dissection | Tumors | Cancer | Original
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