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by Itoh, H and Inoue, M
CHEMICAL REVIEWS, ISSN 0009-2665, 09/2019, Volume 119, Issue 17, pp. 10002 - 10031
Macrocyclic natural products have been recognized and utilized as new platforms for designing drugs in pharmaceutical research because the constrained... 
SOLID-PHASE SYNTHESIS | DIVERTED TOTAL-SYNTHESIS | POTENT BRYOSTATIN ANALOGS | A-RING | DRUG DISCOVERY | ALA-D-ALA | INITIAL BIOLOGICAL EVALUATION | HISTONE-DEACETYLASE INHIBITORS | ORIENTED TOTAL-SYNTHESIS | CHEMISTRY, MULTIDISCIPLINARY | POLYMYXIN-B | Organic chemistry | Construction | Selective binding | Natural products | Optimization
Journal Article
ORGANIC & BIOMOLECULAR CHEMISTRY, ISSN 1477-0520, 7/2019, Volume 17, Issue 27, pp. 6519 - 6527
Fmoc-based solid-phase synthesis provides efficient access to both linear and macrocyclic peptides. To synthesize complex macrocyclic polyamides using Fmoc... 
LANTHIONINE | AMINO-ACIDS | BIOSYNTHESIS | DRUG DISCOVERY | CHEMISTRY | CHEMISTRY, ORGANIC | LANTIBIOTICS | CHEMICAL-SYNTHESIS | LACTICIN 481 | DAPTOMYCIN | STRATEGIES | Solid phase methods | Organic chemistry | Polyamide resins | Amines | Solid phase synthesis | Peptides | Polyamides | Daptomycin | Chain branching | Carboxylic acids | Solid phases
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, p. e66729
Monozygotic (identical) twins have been widely used in genetic studies to determine the relative contributions of heredity and the environment in human... 
PLURIPOTENT STEM-CELLS | DE-NOVO | DNA METHYLATION | MULTIDISCIPLINARY SCIENCES | CREATINE-KINASE-BB | PARENTAL ORIGIN | X-CHROMOSOME INACTIVATION | BECKWITH-WIEDEMANN SYNDROME | NOVO MECP2 MUTATIONS | METHYLATION-SPECIFIC PCR | PRADER-WILLI-SYNDROME | Chromosomes, Human, X - genetics | Twins, Monozygotic - genetics | Exons | Epigenesis, Genetic | Genomics | Humans | Genotype | DNA - metabolism | Genome, Human - genetics | INDEL Mutation | Methyl-CpG-Binding Protein 2 - genetics | DNA Copy Number Variations | DNA - isolation & purification | DNA - chemistry | DNA Methylation | Phenotype | DNA Mutational Analysis | Rett Syndrome - pathology | High-Throughput Nucleotide Sequencing | Polymorphism, Single Nucleotide | Rett Syndrome - genetics | Autism | Medical research | Epigenetic inheritance | Analysis | Genes | Rett syndrome | Medicine, Experimental | Single nucleotide polymorphisms | Twins | Methylation | Gene expression | Brain | Gait | Creatine kinase | Spermatogenesis | Copy number | Hair cells | Insertion | Creatine | Inactivation | Homeobox | Genotype & phenotype | Fibroblasts | Ataxia | Physiology | Deoxyribonucleic acid--DNA | Tyrosine | Heredity | Interdisciplinary aspects | Patients | Neurology | Environmental science | Skin | Mutation | Neurosciences | Ectoderm | Laboratories | Intellectual disabilities | Epilepsy | Genomes | Gene deletion | Tissues | Clonal deletion | Lymphocytes | DNA methylation | Deletion | Seizures | Fyn protein | Deactivation | Legal medicine | Discordance | Birth defects | Environmental factors | Medicine | Brain research | Epigenetics | Genetic engineering | Psychiatry | Deoxyribonucleic acid | DNA
Journal Article
Nature Nanotechnology, ISSN 1748-3387, 09/2017, Volume 12, Issue 9, pp. 907 - 913
Journal Article
Journal Article
ISSN 1359-7345, 12/2013, Volume 5, Issue 8, pp. 939 - 941
We demonstrate the functional control of a dansylated polytheonamide mimic ( 2 ), an artificial ion channel-forming cytotoxic peptide, by the external addition... 
Journal Article
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