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Journal Article
Nature, ISSN 0028-0836, 2014, Volume 506, Issue 7488, pp. 391 - 395
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 04/2015, Volume 112, Issue 14, p. 4316
  Modified DNA bases in mammalian genomes, such as 5-methylcytosine (...C) and its oxidized forms, are implicated in important epigenetic regulation processes.... 
Proteins | Protozoa | Molecules | Mutagenesis | Biochemistry | Genomes | Oxidation
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1602 - 17
Glucagon-like peptide-1 receptor (GLP-1R) activation promotes insulin secretion from pancreatic beta cells, causes weight loss, and is an important... 
ACTIVATION | GLUCAGON-LIKE PEPTIDE-1 | ANALOG | LIRAGLUTIDE | FOOD-INTAKE | MULTIDISCIPLINARY SCIENCES | INSULIN-SECRETION | INDUCED INTERNALIZATION | OPEN-LABEL | REDUCES BLOOD-PRESSURE | BETA-CELL FUNCTION | Cricetulus | Nausea - chemically induced | Humans | Male | Protein Transport - drug effects | Nausea - epidemiology | Glucagon-Like Peptide-1 Receptor - metabolism | Insulin-Secreting Cells - metabolism | Diabetes Mellitus, Experimental | HEK293 Cells | Cell Membrane - metabolism | Insulin - genetics | Cell Membrane - drug effects | CHO Cells | Hypoglycemic Agents - therapeutic use | Glucagon-Like Peptide 1 - metabolism | Endocytosis - drug effects | Mice, Inbred C57BL | Treatment Outcome | Hypoglycemic Agents - pharmacology | Blood Glucose - drug effects | Diabetes Mellitus, Type 2 - blood | Insulin - metabolism | Animals | Insulin-Secreting Cells - drug effects | Mice | Diabetes Mellitus, Type 2 - pathology | Primary Cell Culture | Diabetes Mellitus, Type 2 - drug therapy | Glucagon-Like Peptide-1 Receptor - agonists | RNA, Small Interfering - metabolism | G protein-coupled receptors | Glucagon | Secretion | Diabetes mellitus | Nausea | Arrestin | Pharmacology | Insulin | Protein turnover | Beta cells | Receptors | Endocytosis | Internalization | Protein transport | Pancreas | Diabetes mellitus (non-insulin dependent) | Glucagon-like peptide 1
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 03/2018, Volume 14, Issue 3, pp. 276 - 283
The discovery of functional RNAs that are critical for normal and disease physiology continues to expand at a breakneck pace. Many RNA functions are controlled... 
MAJOR GROOVE | ATOMS LI | SHAPE | U1 SNRNP | RECOGNITION | RNA STRUCTURE | DNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHOTOCHEMISTRY | ZETA-VALENCE QUALITY | GAUSSIAN-BASIS SETS | Solvents | Accessibility | RNA-protein interactions | Photoactivation | Lasers | Protein interaction | Ribonucleic acid--RNA | Cellular structure | Biochemistry & Molecular Biology
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 8594 - 9
Eukaryotic mRNAs are modified at their 5' end early during transcription by the addition of N7-methylguanosine (m(7)G), which forms the "cap" on the first 5'... 
GUANYLYLTRANSFERASE | PROTEIN | MECHANISM | DECAY | MULTIDISCIPLINARY SCIENCES | MODULATOR | FHIT | FAMILY | Enzymes | Yeast | Transcription | Guanosine | Oligonucleotides | Nucleotides | Methylation | Sugar | Base composition
Journal Article
Journal Article
FRONTIERS IN MOLECULAR BIOSCIENCES, ISSN 2296-889X, 04/2019, Volume 6, p. 28
A variant of 9 degrees N DNA polymerase [Genbank ID (AAA88769.1)] with three mutations (D141A, E143A, A485L) and commercialized under the name "Therminator DNA... 
SYSTEM | SUGAR RECOGNITION | NUCLEIC-ACID | REVERSIBLE TERMINATORS | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | functionalized DNA | ENZYMATIC-SYNTHESIS | ARCHAEON | STRUCTURAL DIVERSITY | KINETICS | xenonucleic acids | aptamers | NUCLEOSIDE TRIPHOSPHATES | DNA sequencing | unnatural base pairs | DNA polymerases | Physiological aspects | Genetic aspects | Research
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 04/2018, Volume 115, Issue 14, p. E3116
Certain viruses of bacteria (bacteriophages) enzymatically hypermodify their DNA to protect their genetic material from host restriction endonuclease-mediated... 
Bacteriophages | Salmonella | Phages | Viruses | Homology | Biosynthesis | Biochemistry | Thymidine | Nucleic acids | Gene expression | DNA viruses | Pyrimidines | Historical account | Uridine | Endonuclease | Deoxyribonucleic acid--DNA | Recombinant
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, p. e34003
Journal Article