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Aging Cell, ISSN 1474-9718, 10/2017, Volume 16, Issue 5, pp. 1006 - 1015
Many increasingly prevalent diseases share a common risk factor: age. However, little is known about pharmaceutical interventions against aging, despite many... 
C. elegans | drug repurposing | aging | computational predictions | Drosophila | lifespan | LIFE-SPAN | RESOURCES | C. elegans | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | PROTEIN-LIGAND COMPLEXES | CAENORHABDITIS-ELEGANS | INHIBITION | DATABASE | GENETICS | SEQUENCE | CHEMISTRY | ONTOLOGY | Small Molecule Libraries - pharmacology | Drugs, Investigational - pharmacology | Mitogen-Activated Protein Kinase 14 - antagonists & inhibitors | Humans | Aging - drug effects | Structure-Activity Relationship | Drosophila melanogaster - genetics | Databases, Pharmaceutical | Drosophila melanogaster - metabolism | Drugs, Investigational - chemistry | Aging - genetics | Mitogen-Activated Protein Kinase 14 - metabolism | Healthy Aging - drug effects | Mitogen-Activated Protein Kinase 14 - chemistry | Gene Expression | Healthy Aging - genetics | Caenorhabditis elegans - metabolism | Caenorhabditis elegans - growth & development | Caenorhabditis elegans - genetics | Rats | Mitogen-Activated Protein Kinase 14 - genetics | Drosophila melanogaster - drug effects | Small Molecule Libraries - chemistry | Animals | Caenorhabditis elegans - drug effects | High-Throughput Screening Assays | Healthy Aging - metabolism | Drug Repositioning - methods | Drosophila melanogaster - growth & development | Mice | Molecular Docking Simulation | Aging - metabolism | Drugs | Rankings | Analysis | Protein binding | Isoflavones | Conserved sequence | Orthology | Insects | Life span | Aging | Nematodes | Amino acid sequence | Bioavailability | Index Medicus | Life Sciences | Biochemistry, Molecular Biology | Original
Journal Article
Cell Reports, ISSN 2211-1247, 04/2016, Volume 15, Issue 3, pp. 638 - 650
Journal Article
PLoS Genetics, ISSN 1553-7390, 03/2017, Volume 13, Issue 3, p. e1006593
Journal Article
by Hollingworth, P and Harold, D and Sims, R and Gerrish, A and Lambert, J.C and Carrasquillo, M.M and Abraham, R and Hamshere, M.L and Pahwa, J.S and Moskvina, V and Dowzell, K and Jones, N and Stretton, A and Thomas, C and Richards, A and Ivanov, D and Widdowson, C and Chapman, J and Lovestone, S and Powell, J and Proitsi, P and Lupton, M.K and Brayne, C and Rubinsztein, D.C and Gill, M and Lawlor, B and Lynch, A and Brown, K.S and Passmore, P.A and Craig, D and McGuinness, B and Todd, S and Holmes, C and Mann, D and Smith, A.D and Beaumont, H and Warden, D and Wilcock, G and Love, S and Kehoe, P.G and Hooper, N.M and Vardy, E.R.L.C and Hardy, J and Mead, S and Fox, N.C and Rossor, M and Collinge, J and Maier, W and Jessen, F and Ruther, E and Schurmann, B and Heun, R and Kolsch, H and van den Bussche, H and Heuser, I and Kornhuber, J and Wiltfang, J and Dichgans, M and Frolich, L and Hampel, H and Gallacher, J and Hull, M and Rujescu, D and Giegling, I and Goate, A.M and Kauwe, J.S.K and Cruchaga, C and Nowotny, P and Morris, J.C and Mayo, K and Sleegers, K and Bettens, K and Engelborghs, S and de Deyn, P.P and Van Broeckhoven, C and Livingston, G and Bass, N.J and Gurling, H and McQuillin, A and Gwilliam, R and Deloukas, P and Al-Chalabi, A and Shaw, C.E and Tsolaki, M and Singleton, A.B and Guerreiro, R and Muhleisen, T. W and Nothen, M. M and Moebus, S and Jockel, K.H and Klopp, N and Wichmann, H. E and Pankratz, V.S and Sando, S.B and Aasly, J.O and Barcikowska, M and Wszolek, Z.K and Dickson, D.W and Graff-Radford, N.R. and others and Alzheimer's Dis Neuroimaging and EADI1 Consortium and CHARGE Consortium and Alzheimer's Disease Neuroimaging Initiative and EADI1 consortium and CHARGE consortium and the Alzheimer's Disease Neuroimaging Initiative
Nature Genetics, ISSN 1061-4036, 2011, Volume 43, Issue 5, pp. 429 - 435
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by Jones, Lesley and Holmans, Peter A and Hamshere, Marian L and Harold, Denise and Moskvina, Valentina and Ivanov, Dobril and Pocklington, Andrew and Abraham, Richard and Hollingworth, Paul and Sims, Rebecca and Gerrish, Amy and Pahwa, Jaspreet Singh and Jones, Nicola and Stretton, Alexandra and Morgan, Angharad R and Lovestone, Simon and Powell, John and Proitsi, Petroula and Lupton, Michelle K and Brayne, Carol and Rubinsztein, David C and Gill, Michael and Lawlor, Brian and Lynch, Aoibhinn and Morgan, Kevin and Brown, Kristelle S and Passmore, Peter A and Craig, David and Mcguinness, Bernadette and Todd, Stephen and Holmes, Clive and Mann, David and Smith, A. David and Love, Seth and Kehoe, Patrick G and Mead, Simon and Fox, Nick and Rossor, Martin and Collinge, John and Maier, Wolfgang and Jessen, Frank and Schürmann, Britta and van den Bussche, Hendrik and Heuser, Isabella and Peters, Oliver and Kornhuber, Johannes and Wiltfang, Jens and Dichgans, Martin and Frölich, Lutz and Harald, Hampel and Hüll, Michael and Rujescu, Dan and Goate, Alison M and Kauwe, John S. K and Cruchaga, Carlos and Nowotny, Petra and Morris, John C and Mayo, Kevin and Livingston, Gill and Bass, Nicholas J and Gurling, Hugh and Mcquillin, Andrew and Gwilliam, Rhian and Deloukas, Panos and Al-Chalabi, Ammar and Shaw, Christopher E and Singleton, Andrew B and Guerreiro, Rita and Mühleisen, Thomas W and Nöthen, Markus M and Moebus, Susanne and Jöckel, Karl-Heinz and Klopp, Norman and Wichmann, H.-Erich and Rüther, Eckhard and Carrasquillo, Minerva M and Pankratz, V. Shane and Younkin, Steven G and Hardy, John and O'Donovan, Michael C and Owen, Michael J and Williams, Julie
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 11, pp. e13950 - e13950
Journal Article
PLOS ONE, ISSN 1932-6203, 07/2019, Volume 14, Issue 7, p. e0218111
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, pp. P1120 - P1120
Journal Article
Journal Article