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Journal Article
Scientific reports, ISSN 2045-2322, 02/2019, Volume 9, Issue 1, pp. 2599 - 2599
Modulation by neuropeptides enhances several functions of acid-sensing ion channels (ASICs), such as pain sensation and acid-induced neuronal injury. The... 
Sodium channels | Pain perception | Molecular modelling | Acids | Acidification | Neuropeptides | Ion channels | Acidity | Neuromodulation | Binding sites
Journal Article
American Journal of Pathology, The, ISSN 0002-9440, 2012, Volume 181, Issue 2, pp. 605 - 615
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2017, Volume 12, Issue 6, pp. e0179201 - e0179201
Antibody based immune-checkpoint blockade therapy is a major breakthrough in oncology, leading to clinical benefit for cancer patients. Among the growing... 
UNTREATED MELANOMA | B-LYMPHOCYTE | ACTIVATION | HERPESVIRUS ENTRY MEDIATOR | MULTIDISCIPLINARY SCIENCES | LYMPHOCYTE ATTENUATOR | BTLA | RECEPTOR | CANCER-IMMUNOTHERAPY | IPILIMUMAB | CHECKPOINT BLOCKADE | Cell proliferation | Therapy | Cysteine | Thiols | Peptides | Herpes simplex | Viruses | Oncology | Lymphocytes T | Design analysis | Assaying | T cells | Cancer therapies | Recombinant proteins | Urology | Fragmentation | Enzyme-linked immunoassays | Design | Analogs | Proteins | Receptors | Cell growth | BTLA protein | Lymphocytes | Immunotherapy | Attenuation | Bioinformatics | Enzyme-linked immunosorbent assay | Crystal structure | Binding | Medical research | Antigens | Immunoglobulins | Disulfide bonds | Melanoma | Blocking | T cell receptors | Patients | Switzerland | Protein interactions | Lymphocytes B | Ligands | In vitro methods and tests | Cancer | Amino Acid Sequence | Cell Line | Receptors, Immunologic - chemistry | Peptides - chemistry | Humans | Receptors, Tumor Necrosis Factor, Member 14 - chemistry | Neoplasms - drug therapy | Peptides - pharmacology | Receptors, Tumor Necrosis Factor, Member 14 - metabolism | Peptides - chemical synthesis | Neoplasms - immunology | T-Lymphocytes - drug effects | Protein Binding - drug effects | Drug Design | T-Lymphocytes - immunology | Cysteine - metabolism | Neoplasms - pathology | Peptides - therapeutic use | Receptors, Immunologic - metabolism | Usage | Cancer patients | Care and treatment | Research | Index Medicus | Medicinal Chemistry | Life Sciences | Immunology | Chemical Sciences
Journal Article
PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 8, pp. e72051 - e72051
Journal Article
European Journal of Human Genetics, ISSN 1018-4813, 03/2018, Volume 26, Issue 3, pp. 330 - 339
Journal Article
Genetics in Medicine, ISSN 1098-3600, 07/2018, Volume 20, Issue 7, pp. 778 - 784
Journal Article
Blood, ISSN 0006-4971, 09/2016, Volume 128, Issue 11, pp. 1490 - 1502
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 2, pp. e16903 - e16903
Background: Their large scaffold diversity and properties, such as structural complexity and drug similarity, form the basis of claims that natural products... 
HIT-TO-LEAD | KAPPA-B-KINASE | POTENT | BETA INHIBITORS | MECHANISM | DATABASE | PRODUCTS | DRUG DISCOVERY | BIOLOGY | DERIVATIVES | PROTEIN-KINASES | Competition | Similarity | Homology | Genomes | Drug development | Kinases | Hydrogen bonding | Data bases | Complexity | Clusters | Reliability analysis | Bioinformatics | Protein kinases | Protein structure databases | NF-κB protein | Oxygen | Antiinflammatory agents | Threonine | Drug interactions | Sequence alignment | Pharmacology | Inflammation | Permeability | Lead compounds | Biological activity | Spain | Screening | Inhibitors | Natural products | Protein kinase | Ligands | Kinase inhibitors | ATP | Sequence motif analysis | Amino Acid Sequence | User-Computer Interface | Computational Biology - methods | Reproducibility of Results | Protein Structure, Secondary | Humans | Enzyme Inhibitors - pharmacology | Enzyme Assays - methods | Models, Molecular | Molecular Sequence Data | Biological Products - pharmacology | Catalytic Domain - physiology | Biological Products - isolation & purification | Enzyme Inhibitors - isolation & purification | Sequence Homology | Libraries, Digital | I-kappa B Kinase - metabolism | I-kappa B Kinase - antagonists & inhibitors | Biological Products - analysis | I-kappa B Kinase - chemistry | High-Throughput Screening Assays - methods | Protein Structure, Tertiary - physiology | Medical screening | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2017, Volume 12, Issue 6
Antibody based immune-checkpoint blockade therapy is a major breakthrough in oncology, leading to clinical benefit for cancer patients. Among the growing... 
Life Sciences
Journal Article
The EMBO Journal, ISSN 0261-4189, 10/2011, Volume 30, Issue 20, pp. 4126 - 4141
Journal Article