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Journal of Labelled Compounds and Radiopharmaceuticals, ISSN 0362-4803, 08/2018, Volume 61, Issue 10, pp. i - i
Journal Article
Journal of Labelled Compounds and Radiopharmaceuticals, ISSN 0362-4803, 08/2018, Volume 61, Issue 10, p. i
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 05/2011, Volume 36, Issue 6, pp. 1207 - 1218
  Sigma (σ) receptors have been implicated in the behavioral and motivational effects of alcohol and psychostimulants. Sigma receptor antagonists reduce the... 
binge-like OR binge | dependence | self-administration | alcohol and alcoholism | addiction and substance abuse | alcohol OR ethanol
Journal Article
Journal of Labelled Compounds and Radiopharmaceuticals, ISSN 0362-4803, 08/2018, Volume 61, Issue 10, pp. 773 - 779
Journal Article
Journal of Labelled Compounds and Radiopharmaceuticals, ISSN 0362-4803, 08/2018, Volume 61, Issue 10, pp. 773 - 779
Cannabinoid-1 receptor (CB R) antagonists/inverse agonists have great potential in the treatment of metabolic disorders like dyslipidemia, type 2 diabetes, and... 
R CB | iNOS | DMPK | NASH | ADME | PSA
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2018, Volume 115, Issue 45, p. 11597
Receptor-type protein tyrosine phosphatase D (PTPRD) is a neuronal cell-adhesion molecule/synaptic specifier that has been implicated in addiction... 
Tyrosine | Drug addiction | Drug abuse | Narcotics | Toxicity | Lead compounds | Cell adhesion & migration | Proteins | Drug self-administration | Addiction | Antagonist drugs | Reinforcement | Cocaine | Conditioning | Protein-tyrosine-phosphatase
Journal Article
Journal of Labelled Compounds and Radiopharmaceuticals, ISSN 0362-4803, 08/2018, Volume 61, Issue 10, pp. 773 - 779
Cannabinoid‐1 receptor (CB1R) antagonists/inverse agonists have great potential in the treatment of metabolic disorders like dyslipidemia, type 2 diabetes, and... 
CB1R CB2R | iNOS | DMPK | NASH | ADME | PSA | Type 2 diabetes | Analysis | Nitric oxide | Physiological aspects | Liquid chromatography | Enantiomers | Mass spectrometry
Journal Article
Journal of Labelled Compounds and Radiopharmaceuticals, ISSN 0362-4803, 08/2017, Volume 60, Issue 10, p. 460
Journal Article
Organic & Biomolecular Chemistry, ISSN 1477-0520, 08/2014, Volume 12, Issue 37, pp. 7211 - 7232
Three haptens have been synthesized with linkers for attachment to carrier macromolecules at either the piperidino-nitrogen or viaan introduced 3-amino group.... 
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 03/2015, Volume 92, pp. 531 - 539
Racemic N-substituted-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ols containing cis-4a-aralkyl groups were explored as probes for opioid receptors.... 
cis-4a-arylalkyl-1,2,3,4,4a,9ahexahydrobenzofuro[2,3-c]pyridin-6-ols | Synthesis | Opioid receptors | m-and d-receptor antagonists | [35S]GTP-g-S efficacy assays
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 06/2013, Volume 21, Issue 11, p. 3298
Journal Article
Vaccine, ISSN 0264-410X, 2013, Volume 31, Issue 26, pp. 2804 - 2810
Highlights • Liposomes with monophosphoryl lipid A were formulated as adjuvants for haptens. • Heroin analog haptens were conjugated either to the liposomes or... 
Allergy and Immunology | Opiate vaccine | Adjuvant system | Antibodies to heroin haptens | Liposomes containing monophosphoryl lipid A | MEDICINE, RESEARCH & EXPERIMENTAL | SPECIFICITIES | CHOLESTEROL | RATS | ANTIGENS | ALUMINUM-HYDROXIDE | IMMUNOLOGY | DRUG-ABUSE | RELAPSE | PEPTIDES | MORPHINE/HEROIN VACCINE | CODEINE | Adjuvants, Immunologic - administration & dosage | HIV Envelope Protein gp41 - immunology | Lipid A - analogs & derivatives | HIV Envelope Protein gp41 - chemistry | Haptens - immunology | Feasibility Studies | Haptens - chemistry | Lipid A - immunology | Tetanus Toxoid - chemistry | Adjuvants, Immunologic - chemistry | Female | Opioid-Related Disorders - prevention & control | Epitopes, T-Lymphocyte - immunology | Lipid A - chemistry | Lipid A - administration & dosage | Peptides - chemistry | Peptides - immunology | Vaccines - immunology | Heroin - immunology | Opioid-Related Disorders - immunology | Epitopes, T-Lymphocyte - chemistry | Animals | Antibody Formation | Mice | Mice, Inbred BALB C | Liposomes | Tetanus Toxoid - immunology | Viral antibodies | Drug abuse | Alcoholism | Antibodies | Lipids | Tetanus | Heroin | Competition | Peptides | Aluminum | Amino acids | Vaccines | Proteins | Studies | Immunology | Alzheimers disease | Laboratory animals | Binding sites | Cancer | adjuvant system | opiate vaccine | antibodies to heroin haptens
Journal Article
British journal of pharmacology, ISSN 0007-1188, 08/2019
Obesity, an important risk factor for developing chronic kidney disease (CKD), affects the kidneys by two main molecular signaling pathways: the... 
Journal Article
Journal Article
Cell Metabolism, ISSN 1550-4131, 06/2019, Volume 29, Issue 6, pp. 1320 - 1333.e8
Endocannabinoids acting on the cannabinoid-1 receptor (CB R) or ghrelin acting on its receptor (GHS-R ) both promote alcohol-seeking behavior, but an... 
Journal Article
Cell Metabolism, ISSN 1550-4131, 06/2019, Volume 29, Issue 6, p. 1320
Highlights Endocannabinoids acting on the cannabinoid-1 receptor (CB.sub.1R) or ghrelin acting on its receptor (GHS-R.sub.1A) both promote alcohol-seeking... 
Care and treatment | Alcohol, Denatured | Alcoholism | Alcohol | Substance abuse | Research institutes | Fatty acids | Carnitine
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2018, Volume 115, Issue 45, pp. 11597 - 11602
Receptor-type protein tyrosine phosphatase D (PTPRD) is a neuronal cell-adhesion molecule/synaptic specifier that has been implicated in addiction... 
Post-GWAS | Drug discovery | Addiction | Cell adhesion molecule | Stimulant use disorder | CELL-ADHESION MOLECULE | DELTA | MULTIDISCIPLINARY SCIENCES | addiction | ILLUDALIC ACID | KNOCKOUT MICE | drug discovery | stimulant use disorder | SIGMA | GENES | cell adhesion molecule | ADDICTION VULNERABILITY | LAR | CYCLIN-DEPENDENT KINASE-5 | GENOME-WIDE ASSOCIATION | Substance Abuse, Intravenous - enzymology | Neurons - pathology | Receptor-Like Protein Tyrosine Phosphatases, Class 2 - deficiency | Injections, Intravenous | Humans | Narcotic Antagonists - chemical synthesis | Toxicity Tests, Acute | Cocaine-Related Disorders - genetics | Cocaine-Related Disorders - physiopathology | Receptor-Like Protein Tyrosine Phosphatases, Class 2 - antagonists & inhibitors | Self Administration | Toxicity Tests, Chronic | Substance Abuse, Intravenous - drug therapy | Receptor-Like Protein Tyrosine Phosphatases, Class 2 - genetics | Neurons - drug effects | Catheters, Indwelling | Disease Models, Animal | Substance Abuse, Intravenous - physiopathology | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Substance Abuse, Intravenous - genetics | Cocaine-Related Disorders - enzymology | Mice, Knockout | Coumarins - pharmacology | Animals | Conditioning (Psychology) | Coumarins - chemical synthesis | Narcotic Antagonists - pharmacology | Neurons - enzymology | Ligands | Cocaine-Related Disorders - drug therapy | Mice | Reward | Health aspects | Cocaine | Phosphatases | Index Medicus | Biological Sciences
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 05/2009, Volume 34, Issue 6, pp. 1482 - 1493
  Sigma-Receptors (SigRs) have been implicated in behavioral and appetitive effects of psychostimulants and may also modulate the motivating properties of... 
Journal Article
Journal of Labelled Compounds and Radiopharmaceuticals, ISSN 0362-4803, 08/2017, Volume 60, Issue 10, pp. 460 - 465
JD5037 (1) is a potent and selective, peripherally acting inverse agonist of the cannabinoid (CB1R) receptor. Peripheral CB1 receptor antagonists/inverse... 
ADME | CB1R | PSA
Journal Article
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