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Journal Article
Immunity, ISSN 1074-7613, 2008, Volume 28, Issue 5, pp. 675 - 686
Journal Article
Molecular Systems Biology, ISSN 1744-4292, 06/2010, Volume 6, Issue 1, pp. 371 - n/a
Recognition of microbial danger signals by toll‐like receptors (TLR) causes re‐programming of macrophages. To investigate kinase cascades triggered by the TLR4... 
adaptation | fitness profiling | ethanol tolerance | evolution | Toll-like receptors | Phosphoproteome | SILAC | Nascent RNA | Macrophage | toll-like receptors | DENDRITIC CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | macrophage | nascent RNA | SHOCK TRANSCRIPTION FACTOR-1 | MARROW-DERIVED MACROPHAGES | phosphoproteome | INNATE IMMUNE-RESPONSES | SIGNALING PATHWAY | NEGATIVE REGULATION | GENE-EXPRESSION | FUNCTIONAL INTERACTIONS | FACTOR-I RECEPTOR | NF-KAPPA-B | Protein Kinases - metabolism | Transcriptional Activation - genetics | Macrophage Activation - immunology | Transcriptional Activation - drug effects | Cells, Cultured | Toll-Like Receptor 4 - immunology | Enzyme Activation - drug effects | Phosphoproteins - metabolism | Macrophages - enzymology | Transcription Factors - metabolism | Animals | Signal Transduction - drug effects | Lipopolysaccharides - pharmacology | Macrophages - drug effects | Mice | Phosphorylation - drug effects | Macrophage Activation - drug effects | Proteome - metabolism | Macrophages - immunology | TOR protein | Cell culture | Phosphorylation | Peptides | Amino acids | Labelling | Kinases | Macrophages | Phosphatase | Data bases | Lipopolysaccharides | Signal transduction | Receptors | Accuracy | Microorganisms | Phosphoproteins | Stable isotopes | Transcription activation | Bone marrow | Quantitative analysis | Cytokines | Mass spectroscopy | Hazards | TLR4 protein | Ribonucleic acid--RNA | Gene expression | Chromatography | Proteomics | Cytoskeleton | Scientific imaging | Mass spectrometry | Adapter proteins | Binding sites
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 6, pp. 1873 - 1884.e10
Background Langerhans cell (LC) networks play key roles in immunity and tolerance at body surfaces. LCs are established prenatally and can be replenished from... 
Allergy and Immunology | lineage decision | Runt-related transcription factor 3 | TGF-β1 signaling | monocyte differentiation | Kruppel-like factor 4 | Notch | TGF-BETA | COLONY-STIMULATING FACTOR | CORD BLOOD | IMMUNOLOGY | CLUSTER FORMATION | HEMATOPOIETIC PROGENITORS | EPIDERMAL LANGERHANS CELLS | IN-VITRO | ALLERGY | PERIPHERAL-BLOOD MONOCYTES | NOTCH LIGAND | T-CELLS | TGF-beta 1 signaling | Skin - cytology | Embryo, Mammalian | Monocytes - cytology | Humans | Cells, Cultured | Monocytes - metabolism | Fetal Blood - cytology | Inflammation - metabolism | Kruppel-Like Transcription Factors - metabolism | Adult | Dendritic Cells - cytology | Cell Differentiation - physiology | Dendritic Cells - metabolism | Transforming Growth Factor beta1 - pharmacology | Medical colleges | Inflammation | Skin | Dendritic cells | Networks | Correlation | Transcription factors | Profiling | Genes | Differentiation (biology) | Surface chemistry | Activation | Kinases | Macrophages | Dermatitis | Immunity | Blood | Inflammatory diseases | Cell adhesion & migration | Signal transduction | Cell activation | KLF4 protein | Cell fate | Lymphocytes | Eczema | Skin diseases | Mathematical models | Inhibition | Lesions | Kruppel protein | Immunoglobulins | Cytokines | Markers | Gene expression | Cell differentiation | Steady state | Immunological tolerance | Diseases | Monocytes | Ligands | Notch protein
Journal Article
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 01/2006, Volume 203, Issue 1, pp. 15 - 20
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2008, Volume 105, Issue 39, pp. 15058 - 15063
NF-κB is a key transcriptional regulator of inflammatory responses, but also controls expression of prosurvival genes, whose products protect tissues from... 
T lymphocytes | Myeloid cells | Messenger RNA | Disease models | Cytokines | Epithelial cells | Mucosa | Healing | Inflammation | Colitis | NF-κB | Heat shock protein 70 | STAT3 | Apoptosis | PROTECTS MICE | colitis | MULTIDISCIPLINARY SCIENCES | KINASE | apoptosis | BOWEL-DISEASE | NF-kappa B | INHIBITION | EXPERIMENTAL COLITIS | HEAT-SHOCK RESPONSE | MOUSE MODEL | GENES | NF-KAPPA-B | EXPRESSION | Biological Sciences
Journal Article