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Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 07/2019, Volume 27, Issue 13, pp. 2905 - 2913
Since the approval of ibrutinib for the treatment of B-cell malignancies in 2012, numerous clinical trials have been reported using covalent inhibitors to... 
Fragment screen | Bruton’s Tyrosine Kinase (BTK) | Computer aid drug design (CADD)
Journal Article
BIOORGANIC & MEDICINAL CHEMISTRY, ISSN 0968-0896, 07/2019, Volume 27, Issue 13, pp. 2905 - 2913
Since the approval of ibrutinib for the treatment of B-cell malignancies in 2012, numerous clinical trials have been reported using covalent inhibitors to... 
ACTIVATION | DESIGN | CHEMISTRY, MEDICINAL | Fragment screen | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | Bruton's Tyrosine Kinase (BTK) | DISCOVERY | POTENT | B-CELL | GENE | CLONING | BTK | Computer aid drug design (CADD) | EXPRESSION | TEC FAMILY KINASES | Tyrosine | Phenols | Pharmaceutical industry | Drug approval
Journal Article
Pediatrics, ISSN 0031-4005, 09/2006, Volume 118, Issue 3, p. 1225
OBJECTIVE. Past studies have documented the acute benefits of cardiac rehabilitation in children with congenital heart disease. It is not known whether these... 
Care and treatment | Congenital heart disease
Journal Article
Pediatrics, ISSN 0031-4005, 09/2006, Volume 118, Issue 3, pp. e586 - e593
Journal Article
Pediatrics, ISSN 0031-4005, 12/2005, Volume 116, Issue 6, pp. 1339 - 1345
OBJECTIVES: The exercise capacity of children with congenital heart disease (CHD) is often depressed. This depression is thought to be attributable to (1)... 
Journal Article
by Nagel, Joan Davis and Rudick, Joyce and Abramowitch, Steven and Spring, Jillian and Moalli, Pamela and Al Snih, Soham and Samper-Ternent, Rafael and Markides, Kyriakos S and Ottenbacher, Kenneth J and Alley, Dawn and Yerges, Laura and Shardell, Michelle and Metter, E. Jeffrey and Simonsick, Eleanor and Snitker, Soren and Stenholm, Sari and Shuldiner, Alan R and Mitchell, Braxton and Ferrucci, Luigi and Apesoa-Varano, E. Carolina and Hinton, Ladson and Armstrong-Wells, Jennifer and Post, Miriam and Hoover, Whitney and Winn, Virginia and Li, Yan and Gentile, Luciana B and Padmanabha, Divya and Dumur, Catherine I and Baker, Keith D and Baranoski, Amy S and Darcy, Ariana and Michaels, Daniel and Miciek, Renee and Eder, Richard and Storer, Thomas and Montano, Monty and Barr-Anderson, Daheia J and Adams, Alexis W and Beeghly-Fadiel, Alicia and Lu, Wei and Delahanty, Ryan J and Long, Jirong and Zheng, Ying and Ma, Xiangyu and Gao, Yutang and Cai, Qiuyin and Zheng, Wei and Shu, Xiao-Ou and Black, Angela Rose and Bosak, Kelly and Brown, Jessica P and Gravitt, Patti E and Tracy, J. Kathleen and Brown, Laura D and Rozance, Paul J and Thorn, Stephanie R and Friedman, Jacob E and Hay, William W and Castel, Liana D and Hartmann, Katherine and Chen, Heidi and Mayer, Ingrid and Boomershine, Chad and McLellan, Sarah Elizabeth and Cella, David and Catov, Janet M and Dodge, Rhiannon and Roberts, James M and Ness, Roberta B and Chen, Luyun and Yousuf, Aisha and Pacheco, Patricia and Larson, Kindra and Ashton-Miller, James A and DeLancey, John O.L and Ellis, Terry and Cavanaugh, James T and Earhart, Gammon M and Ford, Matthew P and Foreman, K. Bo and Dibble, Leland E and Fields, Julie A and Lunde, Angela M and Hanna, Sherrie M and Smith, Glenn E and Greenaway, Melanie C and Garcia, Lorena and Qi, Lihong and Rasor, Marianne and Bromberger, Joyce and Clark, Cari and Gold, Ellen B and Ghetti, Chiara and Lowder, Jerry L and Skoczylas, Laura C and Nikolajski, Cara and Gill, John C and Martin, Cecilia and Kwong, Cecilia and ...
Journal of Women's Health, ISSN 1540-9996, 10/2011, Volume 20, Issue 10, pp. 1382 - 1413
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 1994, Volume 59, Issue 6, pp. 1485 - 1491
Ketones reacted with 1,2-bis((trimethylsilyl)oxy)cyclobutene (1) under catalysis by boron trifluoride etherate to yield 2,2-disubstituted 1,3-cyclopentanedione... 
CHEMISTRY, ORGANIC | CARBONYL-COMPOUNDS | ETHERS | FREDERICAMYCIN | ZIZAANE SESQUITERPENES
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 09/1996, Volume 118, Issue 37, pp. 8860 - 8870
The synthesis of 9,9-difluoro-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (F2CBI), a difluorocyclopropane analog of the CC-1065 and duocarmycin... 
1,2,9,9A-TETRAHYDROCYCLOPROPABENZINDOL-4-ONE CBI | ELECTROPHILE REACTIVITY | SEQUENCE SPECIFICITY | NONCOVALENT BINDING SELECTIVITY | N3 ALKYLATION | COMMON PHARMACOPHORE | ANTITUMOR ANTIBIOTIC CC-1065 | LEFT-HAND SUBUNIT | ENHANCED FUNCTIONAL ANALOGS | (+)-CC-1065 DNA ALKYLATION | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 12/1997, Volume 62, Issue 25, p. 8722
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 03/1994, Volume 59, Issue 6, p. 1485
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 12/1997, Volume 62, Issue 25, pp. 8722 - 8729
BF3·Et2O-catalyzed geminal acylation of ketones and acetals with 3-methyl-1,2-bis[(trimethylsilyl)oxy)]cyclobutene (3) provided methylcyclopentanediones in... 
2,2-DISUBSTITUTED 1,3-CYCLOPENTANEDIONES | KETALS | KETONES | K EE CHEMISTRY, ORGANIC | ZIZAANE SESQUITERPENES | CHEMISTRY, ORGANIC | MODEL | DERIVATIVES
Journal Article
Journal of Baccalaureate Social Work, ISSN 1084-7219, 10/1998, Volume 4, Issue 1, pp. 37 - 50
This paper discusses specific gatekeeping issues facing social work educators, both university- & agency-based, & uses case analysis to explain how one... 
Journal Article
Journal of Teaching in Social Work, ISSN 0884-1233, 01/1998, Volume 16, Issue 1-2, pp. 179 - 201
Basic differences in temperament, learning styles, motivation, and interaction styles have major impacts on people yet receive little attention in social work... 
Journal Article
Journal of Gay & Lesbian Social Services, ISSN 1053-8720, 12/1996, Volume 5, Issue 4, pp. 87 - 98
Journal Article
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