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Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 06/2017, Volume 66, Issue 5, pp. 698 - 710.e5
TNF is an inflammatory cytokine that upon binding to its receptor, TNFR1, can drive cytokine production, cell survival, or cell death. TNFR1 stimulation causes... 
cytokine | caspase-8 | complex-II | p38 | cell death | MK2 | IAPs | RIPK1 | TNF | necroptosis | KINASE-ACTIVITY | SPATA2 LINKS CYLD | ACTIVATION | UBIQUITIN | INFLAMMATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA-DEPENDENT APOPTOSIS | PROGRAMMED NECROSIS | NF-KAPPA-B | CANCER | SIGNALING COMPLEX | CELL BIOLOGY | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Phosphorylation | Apoptosis - drug effects | Humans | Multiprotein Complexes | Caspase 8 - metabolism | NF-kappa B - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Necrosis | Dose-Response Relationship, Drug | Transfection | Mitogen-Activated Protein Kinase 14 - metabolism | RNA Interference | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Mice, Inbred C57BL | Fas-Associated Death Domain Protein - metabolism | Protein-Serine-Threonine Kinases - genetics | MAP Kinase Kinase Kinases - metabolism | Mice, Knockout | HT29 Cells | Tumor Necrosis Factor-alpha - pharmacology | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Signal Transduction - drug effects | Medical research | Green buildings | Green design | RNA | Tumor necrosis factor | Cell death | Medicine, Experimental | Biochemistry | Research institutes | Genetic transcription | Genetic translation | Sustainable development
Journal Article
Cell Reports, ISSN 2211-1247, 04/2018, Volume 23, Issue 2, pp. 470 - 484
Tumor necrosis factor (TNF) is an inflammatory cytokine that can signal cell survival or cell death. The mechanisms that switch between these distinct outcomes... 
caspase-8 | cell death | MIB2 | IAPs | RIPK1 | TNF | ubiquitin
Journal Article