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Dietary patterns associated with inflammatory biomarkers in a Northern German population
European journal of nutrition, ISSN 1436-6207, 05/2019, pp. 1 - 9
The aim of the present study was to derive overall and sex-specific dietary patterns associated with inflammatory biomarkers in a general population sample...
Wine | Nuts | Vegetables | Cereals | C-reactive protein | Seeds | Fish oils | Inflammation | Regression analysis | Meat | Interleukin 6 | Body mass index | Food chains | Biomarkers | Pasta | Beverages
Wine | Nuts | Vegetables | Cereals | C-reactive protein | Seeds | Fish oils | Inflammation | Regression analysis | Meat | Interleukin 6 | Body mass index | Food chains | Biomarkers | Pasta | Beverages
Journal Article
Pediatrics, ISSN 0031-4005, 12/2013, Volume 132, Issue 6, pp. e1649 - e1658
BACKGROUND: Organophosphate exposures can affect children's neuro-development, possibly due to neurotoxicity induced by acetylcholinesterase (AChE) inhibition,...
AChE | ADD | ADHD | Ecuador | Flower | Inhibitory control | Growth | Memory | Attention | Acetylcholinesterase | Girls | Pesticide | Boys | Neurodevelopment | Agriculture | Children | Inhibition | Plantation | Floriculture | Agricultural communities | Neurobehavioral development | ORGANOPHOSPHATE PESTICIDE EXPOSURE | CHOLINESTERASE | memory | floriculture | PERFORMANCE | boys | girls | agriculture | neurodevelopment | children | plantation | CHLORPYRIFOS EXPOSURE | PEDIATRICS | DEFICITS | neurobehavioral development | PRENATAL EXPOSURE | inhibitory control | pesticide | acetylcholinesterase | inhibition | agricultural communities | flower | VARIABILITY | METABOLITE LEVELS | attention | growth | Memory - drug effects | Cholinesterase Inhibitors - toxicity | Humans | Child, Preschool | Male | Flowers | Attention - physiology | Attention - drug effects | Female | Child Development - drug effects | Child Development - physiology | Child | Organophosphates - toxicity | Inhibition (Psychology) | Acetylcholinesterase - blood | Cross-Sectional Studies | Linear Models | Biomarkers - blood | Environmental Exposure - adverse effects | Neuropsychological Tests | Health Surveys | Sex Factors | Insecticides - toxicity | Memory - physiology | Physiological aspects | Brain research | Research | Index Medicus | Abridged Index Medicus
AChE | ADD | ADHD | Ecuador | Flower | Inhibitory control | Growth | Memory | Attention | Acetylcholinesterase | Girls | Pesticide | Boys | Neurodevelopment | Agriculture | Children | Inhibition | Plantation | Floriculture | Agricultural communities | Neurobehavioral development | ORGANOPHOSPHATE PESTICIDE EXPOSURE | CHOLINESTERASE | memory | floriculture | PERFORMANCE | boys | girls | agriculture | neurodevelopment | children | plantation | CHLORPYRIFOS EXPOSURE | PEDIATRICS | DEFICITS | neurobehavioral development | PRENATAL EXPOSURE | inhibitory control | pesticide | acetylcholinesterase | inhibition | agricultural communities | flower | VARIABILITY | METABOLITE LEVELS | attention | growth | Memory - drug effects | Cholinesterase Inhibitors - toxicity | Humans | Child, Preschool | Male | Flowers | Attention - physiology | Attention - drug effects | Female | Child Development - drug effects | Child Development - physiology | Child | Organophosphates - toxicity | Inhibition (Psychology) | Acetylcholinesterase - blood | Cross-Sectional Studies | Linear Models | Biomarkers - blood | Environmental Exposure - adverse effects | Neuropsychological Tests | Health Surveys | Sex Factors | Insecticides - toxicity | Memory - physiology | Physiological aspects | Brain research | Research | Index Medicus | Abridged Index Medicus
Journal Article
Nature Methods, ISSN 1548-7091, 10/2011, Volume 8, Issue 10, pp. 841 - 843
In a multicenter study, we determined the expression profiles of 863 microRNAs by array analysis of 454 blood samples from human individuals with different...
EXPRESSION | CANCER | MICRORNA SIGNATURES | BIOCHEMICAL RESEARCH METHODS | Disease - genetics | Oligonucleotide Array Sequence Analysis | Humans | Gene Expression Profiling | Genetic Variation - genetics | MicroRNAs - blood | MicroRNAs - genetics | Reverse Transcriptase Polymerase Chain Reaction | Polymerase chain reaction | Physiological aspects | Usage | MicroRNA | Research | Genetic variation | Disease | Gene expression | Ribonucleic acid--RNA | Genomics | Blood | Cancer
EXPRESSION | CANCER | MICRORNA SIGNATURES | BIOCHEMICAL RESEARCH METHODS | Disease - genetics | Oligonucleotide Array Sequence Analysis | Humans | Gene Expression Profiling | Genetic Variation - genetics | MicroRNAs - blood | MicroRNAs - genetics | Reverse Transcriptase Polymerase Chain Reaction | Polymerase chain reaction | Physiological aspects | Usage | MicroRNA | Research | Genetic variation | Disease | Gene expression | Ribonucleic acid--RNA | Genomics | Blood | Cancer
Journal Article
Nature Communications, ISSN 2041-1723, 01/2016, Volume 7, Issue 1, p. 10023
Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality. We conducted a meta-analysis...
SERUM CREATININE | INDIVIDUALS | POPULATION | METAANALYSIS | VARIANTS | MULTIDISCIPLINARY SCIENCES | RISK | FALSE DISCOVERY RATES | HYPERTENSION | STAGE RENAL-DISEASE | GENOME-WIDE ASSOCIATION | Genotype | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | Gene Expression Regulation | Renal Insufficiency, Chronic - genetics | Genetik | Biological Sciences | Genetics | Naturvetenskap | Natural Sciences | Biologiska vetenskaper
SERUM CREATININE | INDIVIDUALS | POPULATION | METAANALYSIS | VARIANTS | MULTIDISCIPLINARY SCIENCES | RISK | FALSE DISCOVERY RATES | HYPERTENSION | STAGE RENAL-DISEASE | GENOME-WIDE ASSOCIATION | Genotype | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | Gene Expression Regulation | Renal Insufficiency, Chronic - genetics | Genetik | Biological Sciences | Genetics | Naturvetenskap | Natural Sciences | Biologiska vetenskaper
Journal Article
Nature Genetics, ISSN 1061-4036, 09/2008, Volume 40, Issue 9, pp. 1103 - 1106
Sarcoidosis is a complex chronic inflammatory disorder with predominant manifestation in the lung. In the first genome-wide association study (4440,000 SNPs)...
APOPTOSIS | DOMAIN | PROTEIN | SEARCH | ALG-2 | GENETICS & HEREDITY | ANNEXIN-XI | IL-15 | AFRICAN-AMERICANS | BTNL2 GENE | EXPRESSION | Amino Acid Sequence | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | Sarcoidosis - genetics | Models, Molecular | Chromosome Mapping | Annexins - genetics | Sequence Analysis, Protein | Validation Studies as Topic | Polymorphism, Single Nucleotide | Genome, Human | Chromosomes, Human, Pair 10 | Physiological aspects | Genetic aspects | Research | Single nucleotide polymorphisms | Sarcoidosis | Risk factors | Data analysis | Racial differences | Rheumatoid arthritis | Cell division | Genetics | Binding sites | Apoptosis
APOPTOSIS | DOMAIN | PROTEIN | SEARCH | ALG-2 | GENETICS & HEREDITY | ANNEXIN-XI | IL-15 | AFRICAN-AMERICANS | BTNL2 GENE | EXPRESSION | Amino Acid Sequence | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | Sarcoidosis - genetics | Models, Molecular | Chromosome Mapping | Annexins - genetics | Sequence Analysis, Protein | Validation Studies as Topic | Polymorphism, Single Nucleotide | Genome, Human | Chromosomes, Human, Pair 10 | Physiological aspects | Genetic aspects | Research | Single nucleotide polymorphisms | Sarcoidosis | Risk factors | Data analysis | Racial differences | Rheumatoid arthritis | Cell division | Genetics | Binding sites | Apoptosis
Journal Article
Cancer Causes & Control, ISSN 0957-5243, 10/2014, Volume 25, Issue 10, pp. 1407 - 1418
Purpose: Aim of this study was to investigate the association between postdiagnosis body mass index (BMI) and all-cause mortality in colorectal cancer (CRC)...
Body mass index | Obesity | Meta analysis | Mortality | Colorectal cancer | Underweight | Tobacco smoking | Alcohol drinking | Overweight | Cancer | Public Health | Biomedicine | Hematology | Survivors | Cancer Research | Oncology | Colorectal neoplasms | Epidemiology | Biomedicine general | UNITED-STATES | CACHEXIA | TREATMENT-RELATED TOXICITY | OBESITY | IMPACT | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | ONCOLOGY | OVERWEIGHT | PHYSICAL-ACTIVITY | RECURRENCE | OUTCOMES | ASSOCIATION | Body Mass Index | Colorectal Neoplasms - mortality | Prospective Studies | Comorbidity | Humans | Middle Aged | Risk Factors | Survivors - statistics & numerical data | Proportional Hazards Models | Male | Survival Rate | Cause of Death | Colorectal Neoplasms - diagnosis | Incidence | Thinness - epidemiology | Overweight - epidemiology | Alcohol Drinking - epidemiology | Smoking - epidemiology | Obesity - epidemiology | Female | Surveys and Questionnaires | Aged | Germany | Cohort Studies | Diagnosis | Patient outcomes | Analysis | Risk factors
Body mass index | Obesity | Meta analysis | Mortality | Colorectal cancer | Underweight | Tobacco smoking | Alcohol drinking | Overweight | Cancer | Public Health | Biomedicine | Hematology | Survivors | Cancer Research | Oncology | Colorectal neoplasms | Epidemiology | Biomedicine general | UNITED-STATES | CACHEXIA | TREATMENT-RELATED TOXICITY | OBESITY | IMPACT | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | ONCOLOGY | OVERWEIGHT | PHYSICAL-ACTIVITY | RECURRENCE | OUTCOMES | ASSOCIATION | Body Mass Index | Colorectal Neoplasms - mortality | Prospective Studies | Comorbidity | Humans | Middle Aged | Risk Factors | Survivors - statistics & numerical data | Proportional Hazards Models | Male | Survival Rate | Cause of Death | Colorectal Neoplasms - diagnosis | Incidence | Thinness - epidemiology | Overweight - epidemiology | Alcohol Drinking - epidemiology | Smoking - epidemiology | Obesity - epidemiology | Female | Surveys and Questionnaires | Aged | Germany | Cohort Studies | Diagnosis | Patient outcomes | Analysis | Risk factors
Journal Article
Aging Cell, ISSN 1474-9718, 08/2012, Volume 11, Issue 4, pp. 607 - 616
Summary Little is known about the functions of miRNAs in human longevity. Here, we present the first genome‐wide miRNA study in long‐lived individuals (LLI)...
p53 tumor suppressor network | clustering | differentially regulated aging‐related miRNA signatures | long‐lived individuals | centenarians | P53 tumor suppressor network | Centenarians | Clustering | Differentially regulated aging-related miRNA signatures | Long-lived individuals | TARGET | CANCER | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | long-lived individuals | DISEASE | GENES | ENRICHMENT | differentially regulated aging-related miRNA signatures | EXPRESSION | CELL | ASSOCIATION | MICRORNA | REVEALS | Up-Regulation | Reproducibility of Results | Disease - genetics | Oligonucleotide Array Sequence Analysis | Down-Regulation | Humans | Middle Aged | Risk Factors | Male | Genetic Markers | Longevity - genetics | Aging - blood | Aging - genetics | Aged, 80 and over | Adult | Female | Aged | MicroRNAs - blood | MicroRNAs - genetics | MicroRNA | Tumor proteins | Analysis | Genes | Genomics | Tumors | Aging | Genomes | Age
p53 tumor suppressor network | clustering | differentially regulated aging‐related miRNA signatures | long‐lived individuals | centenarians | P53 tumor suppressor network | Centenarians | Clustering | Differentially regulated aging-related miRNA signatures | Long-lived individuals | TARGET | CANCER | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | long-lived individuals | DISEASE | GENES | ENRICHMENT | differentially regulated aging-related miRNA signatures | EXPRESSION | CELL | ASSOCIATION | MICRORNA | REVEALS | Up-Regulation | Reproducibility of Results | Disease - genetics | Oligonucleotide Array Sequence Analysis | Down-Regulation | Humans | Middle Aged | Risk Factors | Male | Genetic Markers | Longevity - genetics | Aging - blood | Aging - genetics | Aged, 80 and over | Adult | Female | Aged | MicroRNAs - blood | MicroRNAs - genetics | MicroRNA | Tumor proteins | Analysis | Genes | Genomics | Tumors | Aging | Genomes | Age
Journal Article
Nature Genetics, ISSN 1061-4036, 08/2011, Volume 43, Issue 8, pp. 753 - 760
textabstractGenome-wide association studies have identified 32 loci influencing body mass index, but this measure does not distinguish lean from fat mass. To...
MIGRATION | FTO GENE | GENETICS & HEREDITY | RESISTANCE | BODY-MASS INDEX | ADIPOCYTE DIFFERENTIATION | LOCI | INSULIN-RECEPTOR SUBSTRATE-1 | ADULT OBESITY | EXPRESSION | GENOME-WIDE ASSOCIATION | Body Mass Index | Genome-Wide Association Study | Meta-Analysis as Topic | Body Weight | Humans | Male | Adiposity - genetics | Obesity - genetics | Metabolome - genetics | Adiponectin - blood | Membrane Proteins | Alleles | Subcutaneous Fat | Polymorphism, Single Nucleotide - genetics | Female | Genetic Variation - genetics | Body Fat Distribution | Insulin Receptor Substrate Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Body mass index | Usage | Receptors | Genetic variation | Physiological aspects | Insulin resistance | Genetic aspects | Research | Insulin | Medical research | Biomedical research | Body fat | Research & development--R&D | Genomes | Meta-analysis | Mens health | Weight control | Hospitals | Womens health | Metabolic disorders | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
MIGRATION | FTO GENE | GENETICS & HEREDITY | RESISTANCE | BODY-MASS INDEX | ADIPOCYTE DIFFERENTIATION | LOCI | INSULIN-RECEPTOR SUBSTRATE-1 | ADULT OBESITY | EXPRESSION | GENOME-WIDE ASSOCIATION | Body Mass Index | Genome-Wide Association Study | Meta-Analysis as Topic | Body Weight | Humans | Male | Adiposity - genetics | Obesity - genetics | Metabolome - genetics | Adiponectin - blood | Membrane Proteins | Alleles | Subcutaneous Fat | Polymorphism, Single Nucleotide - genetics | Female | Genetic Variation - genetics | Body Fat Distribution | Insulin Receptor Substrate Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Body mass index | Usage | Receptors | Genetic variation | Physiological aspects | Insulin resistance | Genetic aspects | Research | Insulin | Medical research | Biomedical research | Body fat | Research & development--R&D | Genomes | Meta-analysis | Mens health | Weight control | Hospitals | Womens health | Metabolic disorders | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
Journal Article
The Lancet Infectious Diseases, ISSN 1473-3099, 08/2018, Volume 18, Issue 8, pp. e248 - e258
Low-resource settings are disproportionately burdened by infectious diseases and antimicrobial resistance. Good quality clinical bacteriology through a well...
GLOBAL BURDEN | INFECTIOUS DISEASES | LABORATORY SERVICES | MANAGEMENT | SUB-SAHARAN AFRICA | HEALTH-CARE EPIDEMIOLOGY | TOF MASS-SPECTROMETRY | IDENTIFICATION | SEVERE FEBRILE ILLNESS | BLOOD-STREAM INFECTIONS | KLEBSIELLA-PNEUMONIAE | Bacteriological Techniques - standards | Drug Resistance, Microbial | Bacteriological Techniques - methods | Cross Infection - prevention & control | Laboratories | Humans | Bacteriology - standards | Health Resources - supply & distribution | Developing Countries | Quality Assurance, Health Care | Drug resistance in microorganisms | Dancing | Cross infection | Nosocomial infections | Public health | Low income groups | Salmonella | Income | Information management | Drug resistance | Antiinfectives and antibacterials | Tropical diseases | Streptococcus infections | Quality assurance | Quality | Humidity | Bacteria | Manufacturing | Urogenital system | Adaptation | Containment | Bacterial infections | Cold | Mortality | Health care policy | Manufacturers | Antimicrobial agents | Management tools | Management | Patients | Disease control | Bacteriology | Materials information | Infectious diseases | Tuberculosis | Antibiotics | Surveillance | Sepsis | Antimicrobial resistance | Production capacity | Resource management
GLOBAL BURDEN | INFECTIOUS DISEASES | LABORATORY SERVICES | MANAGEMENT | SUB-SAHARAN AFRICA | HEALTH-CARE EPIDEMIOLOGY | TOF MASS-SPECTROMETRY | IDENTIFICATION | SEVERE FEBRILE ILLNESS | BLOOD-STREAM INFECTIONS | KLEBSIELLA-PNEUMONIAE | Bacteriological Techniques - standards | Drug Resistance, Microbial | Bacteriological Techniques - methods | Cross Infection - prevention & control | Laboratories | Humans | Bacteriology - standards | Health Resources - supply & distribution | Developing Countries | Quality Assurance, Health Care | Drug resistance in microorganisms | Dancing | Cross infection | Nosocomial infections | Public health | Low income groups | Salmonella | Income | Information management | Drug resistance | Antiinfectives and antibacterials | Tropical diseases | Streptococcus infections | Quality assurance | Quality | Humidity | Bacteria | Manufacturing | Urogenital system | Adaptation | Containment | Bacterial infections | Cold | Mortality | Health care policy | Manufacturers | Antimicrobial agents | Management tools | Management | Patients | Disease control | Bacteriology | Materials information | Infectious diseases | Tuberculosis | Antibiotics | Surveillance | Sepsis | Antimicrobial resistance | Production capacity | Resource management
Journal Article