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fetal echocardiography (10) 10
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1. Full Text The Importance of the Level of Maternal Anti-Ro/SSA Antibodies as a Prognostic Marker of the Development of Cardiac Neonatal Lupus Erythematosus. A Prospective Study of 186 Antibody-Exposed Fetuses and Infants
by Jaeggi, Edgar and Laskin, Carl and Hamilton, Robert and Kingdom, John and Silverman, Earl
Journal of the American College of Cardiology, ISSN 0735-1097, 06/2010, Volume 55, Issue 24, pp. 2778 - 2784
Objectives: The purpose of this study was to determine whether cardiac complications of neonatal lupus erythematosus (NLE) are related to maternal anti-Ro and... 
heart block | neonatal lupus erythematosus | endocardial fibroelastosis | fetal | anti-Ro antibodies | MOTHERS | AUTOANTIBODIES | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK | COMPLETE ATRIOVENTRICULAR-BLOCK | FIBROELASTOSIS | CHILDREN | CONGENITAL HEART-BLOCK | ASSOCIATION | Prognosis | Prospective Studies | Fetal Diseases - blood | Follow-Up Studies | Antibodies, Antinuclear - immunology | Humans | Lupus Erythematosus, Systemic - congenital | Heart Diseases - congenital | Antibodies, Antinuclear - blood | Lupus Erythematosus, Systemic - embryology | Lupus Erythematosus, Systemic - immunology | Female | Retrospective Studies | Infant, Newborn | Diagnosis, Differential | Enzyme-Linked Immunosorbent Assay | Fetal Diseases - diagnosis | Gestational Age | Pregnancy | Ultrasonography, Prenatal | Fetal Diseases - immunology | Echocardiography, Doppler - methods | Heart Diseases - embryology | Pregnancy Outcome | Heart Diseases - immunology | Pregnancy Complications - immunology | Lupus | Heart | Ultrasonic imaging | Fetuses | Cardiovascular disease | Autoimmune diseases
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2. Full Text Abstract 17036: Transesophageal Electrophysiology Study as a Tool to Guide Post-natal Management of Fetal Supraventricular Tachycardia
by Renaud, Claudia and Vinocur, Jeffrey M and Jaeggi, Edgar
Circulation, ISSN 0009-7322, 11/2016, Volume 134, Issue Suppl_1 Suppl 1, pp. A17036 - A17036
BackgroundWith advancements in fetal echocardiography, the diagnosis of supraventricular tachycardia (SVT) is now often made antenatally. There is wide... 
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3. Full Text Transesophageal electrophysiology study as a tool to guide post-natal management of fetal supraventricular tachycardia
by Jaeggi, Edgar and Renaud, Claudia and Vinocur, Jeffrey M
Circulation, ISSN 0009-7322, 11/2016, Volume 134, Issue 19
Electrophysiology | Usage | Care and treatment | Supraventricular tachycardia | Diagnosis | Arrhythmia
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4. Full Text The association of fetal cerebrovascular resistance with early neurodevelopment in single ventricle congenital heart disease
by Williams, Ismee A., MD, MS and Fifer, Carlen, MD and Jaeggi, Edgar, MD and Levine, Jami C., MD and Michelfelder, Erik C., MD and Szwast, Anita L., MD
American Heart Journal, ISSN 0002-8703, 2013, Volume 165, Issue 4, pp. 544 - 550.e1
Background Children with congenital heart disease are at risk for impaired neurodevelopment (ND). We investigated the association of fetal cerebrovascular... 
Cardiovascular | CARDIAC & CARDIOVASCULAR SYSTEMS | INFANTS | RANDOMIZED-TRIAL | OUTCOMES | FETUSES | PERFUSION | BLOOD-FLOW | CIRCULATORY ARREST | BRAIN | CHILDREN | Multivariate Analysis | Vascular Resistance | Cerebrovascular Circulation - physiology | Pulsatile Flow | Humans | Male | Fetus - physiology | Gestational Age | Oxygen - metabolism | Brain - metabolism | Heart Ventricles - abnormalities | Middle Cerebral Artery - physiopathology | Female | Heart Defects, Congenital - physiopathology | Child Development - physiology | Vasodilation - physiology | Infant, Newborn | Heart | Congenital heart disease | Genetic disorders | Heart diseases | Ultrasonic imaging | Pulmonary arteries | Review boards | Fetuses | Cardiovascular disease | Disclosure | Veins & arteries
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5. Full Text Use of Intravenous Gamma Globulin and Corticosteroids in the Treatment of Maternal Autoantibody-Mediated Cardiomyopathy
by Trucco, Sara M., MD and Jaeggi, Edgar, MD and Cuneo, Bettina, MD and Moon-Grady, Anita J., MD and Silverman, Earl, MD and Silverman, Norman, MD and Hornberger, Lisa K., MD
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2011, Volume 57, Issue 6, pp. 715 - 723
Objectives This study sought to evaluate the outcome of maternal autoantibody-mediated fetal cardiomyopathy/endocardial fibroelastosis following intravenous... 
Cardiovascular | Internal Medicine | fetal echocardiography | cardiomyopathy | complete heart block | autoantibodies | autoimmune disease | SYSTEMIC-LUPUS-ERYTHEMATOSUS | CARDIAC & CARDIOVASCULAR SYSTEMS | INFLAMMATORY DISEASES | ANTI-RO AUTOANTIBODIES | IMMUNOGLOBULIN | COMPLETE ATRIOVENTRICULAR-BLOCK | NEONATAL LUPUS | ENDOCARDIAL FIBROELASTOSIS | LA ANTIBODIES | CONGENITAL HEART-BLOCK | FETAL | Fetal Diseases - drug therapy | Endocardial Fibroelastosis - immunology | Autoantibodies | Endocardial Fibroelastosis - drug therapy | Humans | Histocompatibility, Maternal-Fetal | Adrenal Cortex Hormones - therapeutic use | Infant, Newborn, Diseases - drug therapy | Pregnancy | Young Adult | Endocardial Fibroelastosis - congenital | Immunoglobulins, Intravenous - therapeutic use | Fetal Diseases - immunology | Adult | Female | Retrospective Studies | Infant, Newborn | Infant, Newborn, Diseases - immunology | Autoimmunity | Usage | Corticosteroids | Cardiology | Children's hospitals | Heart | Lupus | Cardiac arrhythmia | Cardiomyopathy | Fetuses | Colleges & universities | Cardiovascular disease | Mothers | Sinuses | Autoimmune diseases | Age
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6. Fetal and Neonatal Arrhythmias
by Jaeggi, Edgar and Öhman, Annika
Clinics in Perinatology, ISSN 0095-5108, 03/2016, Volume 43, Issue 1, pp. 99 - 112
Cardiac arrhythmias are an important aspect of fetal and neonatal medicine. Premature complexes of atrial or ventricular origin are the main cause of an... 
Bradycardia | Tachycardia | Fetal | Diagnosis | Arrhythmia | Pediatric | STRUCTURAL HEART-DISEASE | SINGLE INSTITUTION | TIME INTERVALS | LONG-QT SYNDROME | SUPRAVENTRICULAR TACHYCARDIA | COMPLETE ATRIOVENTRICULAR-BLOCK | OBSTETRICS & GYNECOLOGY | TRANSPLACENTAL TREATMENT | ANTI-RO/SSA ANTIBODIES | PEDIATRICS | STEROID-THERAPY | Tachycardia, Supraventricular - drug therapy | Atrial Premature Complexes - drug therapy | Bradycardia - diagnosis | Humans | Sick Sinus Syndrome - diagnosis | Sick Sinus Syndrome - drug therapy | Heart Block - diagnosis | Infant, Newborn, Diseases - drug therapy | Ventricular Premature Complexes - diagnosis | Electrocardiography | Tachycardia, Sinus - diagnosis | Infant, Newborn | Atrial Premature Complexes - diagnosis | Fetal Diseases - drug therapy | Heart Block - drug therapy | Fetal Diseases - diagnosis | Infant, Newborn, Diseases - diagnosis | Tachycardia, Sinus - drug therapy | Anti-Arrhythmia Agents - therapeutic use | Tachycardia, Supraventricular - diagnosis | Arrhythmias, Cardiac - drug therapy | Ventricular Premature Complexes - drug therapy | Atrial Flutter - diagnosis | Atrial Flutter - drug therapy | Arrhythmias, Cardiac - diagnosis | Bradycardia - drug therapy
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7. Full Text Feasibility of quantification of the distribution of blood flow in the normal human fetal circulation using CMR: A cross-sectional study
by Seed, Mike and Van Amerom, Joshua F.P and Yoo, Shi-Joon and Al Nafisi, Bahiyah and Grosse-Wortmann, Lars and Jaeggi, Edgar and Jansz, Michael S and MacGowan, Christopher K
Journal of Cardiovascular Magnetic Resonance, ISSN 1097-6647, 2012, Volume 14, Issue 1, pp. 79 - 79
Background: We present the first phase contrast (PC) cardiovascular magnetic resonance (CMR) measurements of the distribution of blood flow in twelve late... 
Magnetic resonance imaging | Regional blood flow | Circulation | CARDIAC-OUTPUT | CARDIAC & CARDIOVASCULAR SYSTEMS | MRI | DOPPLER ULTRASONOGRAPHY | FETUS | HEART | GESTATIONAL-AGE | ULTRASOUND | WEIGHT | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Fetal Heart - physiology | Predictive Value of Tests | Reproducibility of Results | Prospective Studies | Cross-Sectional Studies | Humans | Perfusion Imaging - methods | Fetal Weight | Linear Models | Cardiac-Gated Imaging Techniques | Magnetic Resonance Imaging, Cine | Gestational Age | Regional Blood Flow | Feasibility Studies | Pregnancy | Fetus - blood supply | Blood Flow Velocity | Adult | Female | Blood Vessels - physiology | Prenatal Diagnosis - methods | Observer Variation | Hemodynamics | Comparative analysis | Blood flow | Human | Magnetic resonance | Aorta | Adults | Standard deviation | Gating and risering | Gestation
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8. Full Text The hemodynamics of late-onset intrauterine growth restriction by MRI
by Zhu, Meng Yuan, MS and Milligan, Natasha, MS and Keating, Sarah, MD and Windrim, Rory, MD and Keunen, Johannes, MD and Thakur, Varsha, MD and Ohman, Annika, MD and Portnoy, Sharon, MS and Sled, John G., PhD and Kelly, Edmond, MD and Yoo, Shi-Joon, MD, PhD and Gross-Wortmann, Lars, MD and Jaeggi, Edgar, MD and MacGowan, Christopher K., PhD and Kingdom, John C., MD and Seed, Mike, MBBS
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 2015, Volume 214, Issue 3, pp. 367.e1 - 367.e17
Background Late-onset intrauterine growth restriction (IUGR) results from a failure of the placenta to supply adequate nutrients and oxygen to the rapidly... 
Obstetrics and Gynecology | intrauterine growth restriction | magnetic resonance imaging | small for gestational age | Doppler | fetus | QUANTIFICATION | BLOOD-OXYGEN SATURATION | BIRTH-WEIGHT | HYPOXEMIA | TERM | FLOW | OBSTETRICS & GYNECOLOGY | HEART | HUMAN FETAL CIRCULATION | BRAIN | CONSUMPTION | Brain - embryology | Fetal Growth Retardation - diagnostic imaging | Prospective Studies | Pulsatile Flow | Area Under Curve | Humans | Case-Control Studies | Oxygen - metabolism | Placental Circulation | Adult | Female | Middle Cerebral Artery - physiology | Fetal Growth Retardation - diagnosis | Infant, Newborn | Vena Cava, Superior - physiology | Middle Cerebral Artery - diagnostic imaging | Pregnancy Trimester, Third - physiology | Ultrasonography, Doppler | Oxygen Consumption | Umbilical Arteries - physiology | Umbilical Arteries - diagnostic imaging | Cerebrovascular Circulation | Vena Cava, Superior - diagnostic imaging | Regional Blood Flow | Fetal Growth Retardation - physiopathology | Pregnancy | Birth Weight | Magnetic Resonance Imaging | Placenta - blood supply | Placenta - pathology | ROC Curve | Hemodynamics | Magnetic resonance imaging | Cardiology | Growth | Fetus
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9. Full Text Comparison between Different Speckle Tracking and Color Tissue Doppler Techniques to Measure Global and Regional Myocardial Deformation in Children
by Koopman, Laurens P., MD, PhD and Slorach, Cameron, RDCS and Hui, Wei, RDCS and Manlhiot, Cedric, BSc and McCrindle, Brian W., MD, MPH and Friedberg, Mark K., MD and Jaeggi, Edgar T., MD and Mertens, Luc, MD, PhD
Journal of the American Society of Echocardiography, ISSN 0894-7317, 2010, Volume 23, Issue 9, pp. 919 - 928
Background Myocardial deformation parameters obtained by speckle-tracking echocardiography (STE) and color Doppler tissue imaging (CDTI) using two different... 
Cardiovascular | Myocardial deformation | Color Doppler tissue imaging | Children | Speckle tracking | STRAIN-RATE | CARDIAC & CARDIOVASCULAR SYSTEMS | QUANTIFICATION | VALIDATION | TETRALOGY | HEALTHY-CHILDREN | LONGITUDINAL STRAIN | MAGNETIC-RESONANCE | 2-DIMENSIONAL SPECKLE | ECHOCARDIOGRAPHY | LEFT-VENTRICULAR FUNCTION | Reproducibility of Results | Prospective Studies | Heart Defects, Congenital - diagnostic imaging | Humans | Adolescent | Echocardiography - methods | Child, Preschool | Image Interpretation, Computer-Assisted | Female | Male | Echocardiography, Doppler, Color | Child | Healthcare industry software | Cardiology | Children's hospitals | Methods
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10. Full Text Assessment of Myocardial Deformation in Children Using Digital Imaging and Communications in Medicine (DICOM) Data and Vendor Independent Speckle Tracking Software
by Koopman, Laurens P., MD, PhD and Slorach, Cameron, RCDS and Manlhiot, Cedric, BSc and McCrindle, Brian W., MD, MPH and Jaeggi, Edgar T., MD and Mertens, Luc, MD, PhD and Friedberg, Mark K., MD
Journal of the American Society of Echocardiography, ISSN 0894-7317, 2011, Volume 24, Issue 1, pp. 37 - 44
Background Analysis of myocardial deformation from data stored in Digital Imaging and Communications in Medicine format using vendor-independent software may... 
Cardiovascular | Myocardial deformation | DICOM data | Vendor-independent software | Child | VELOCITY | CARDIAC & CARDIOVASCULAR SYSTEMS | CARDIOMYOPATHY | VALIDATION | 2-DIMENSIONAL STRAIN | ECHOCARDIOGRAPHY | TISSUE DOPPLER | ACCURACY | Heart - physiopathology | Radiology Information Systems | Reproducibility of Results | Heart Diseases - physiopathology | Humans | Image Interpretation, Computer-Assisted - methods | Echocardiography - methods | Child, Preschool | Male | Elastic Modulus | Elasticity Imaging Techniques - methods | Algorithms | Anisotropy | Sensitivity and Specificity | Adolescent | Female | Heart Diseases - diagnostic imaging | Computer software industry | Healthcare industry software | Software
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11. Full Text An unusual course of anti-Ro antibody-mediated fetal complete heart block
by Renaud, Claudia and Jaeggi, Edgar and Thakur, Varsha
Cardiology in the Young, ISSN 1047-9511, 01/2018, Volume 28, Issue 1, pp. 171 - 174
Fetal hydrops is a serious complication of immune-mediated congenital complete atrioventricular block. We present the case of a fetus with severe hydrops and... 
Complete heart block | hydrops | ventricular ectopy | fetal | anti-Ro antibodies | CARDIAC & CARDIOVASCULAR SYSTEMS | PEDIATRICS | ATRIOVENTRICULAR-BLOCK | RO/SSA ANTIBODIES | Heart | Lupus | Edema | Cardiac arrhythmia | Immunoglobulins | Congenital diseases | Fetuses | Families & family life | Cardiovascular disease | Inflammation | Pregnancy | Heart rate | Bradycardia | Electrocardiography | Ventricle | Cardiac output | Heart diseases
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12. Full Text Congenital Heart Block Maternal Sera Autoantibodies Target an Extracellular Epitope on the α1G T-Type Calcium Channel in Human Fetal Hearts
by Strandberg, Linn S and Cui, Xuezhi and Rath, Arianna and Liu, Jie and Silverman, Earl D and Liu, Xiaoru and Siragam, Vinayakumar and Ackerley, Cameron and Su, Brenda Bin and Yan, Jane Yuqing and Capecchi, Marco and Biavati, Luca and Accorroni, Alice and Yuen, William and Quattrone, Filippo and Lung, Kalvin and Jaeggi, Edgar T and Backx, Peter H and Deber, Charles M and Hamilton, Robert M
PLoS ONE, ISSN 1932-6203, 09/2013, Volume 8, Issue 9, p. e72668
Congenital heart block (CHB) is a transplacentally acquired autoimmune disease associated with anti-Ro/SSA and anti-La/SSB maternal autoantibodies and is... 
Epitope Mapping | Myocytes, Cardiac - immunology | Autoantibodies - blood | Humans | Molecular Sequence Data | Male | Extracellular Space | Atrioventricular Node - drug effects | Epitopes - immunology | Calcium Channels, T-Type - chemistry | Female | Calcium Channels, T-Type - genetics | Fetal Heart - metabolism | Maternal-Fetal Exchange - immunology | Amino Acid Sequence | Rabbits | Gene Expression | Peptides - immunology | Calcium Channel Blockers - pharmacology | Heart Block - immunology | Heart Block - genetics | Atrioventricular Node - metabolism | Pregnancy | Autoantibodies - immunology | Animals | Fetal Heart - drug effects | Autoantigens - immunology | Myocytes, Cardiac - metabolism | Fetal Heart - immunology | Heart Block - congenital | Mice | Calcium Channels, T-Type - immunology | Heart | Cardiac arrhythmia | Congenital heart block | Immunoprecipitation | Calcium | Molecular structure | Antibodies | Electrophysiology | Amino acids | Homology | Gestation | Proteins | Ro(SSA) antigen | Sinuses | Rodents | Physiology | Enzyme-linked immunosorbent assay | Calcium channels | Immunoglobulins | Congenital diseases | Autoantibodies | Fetuses | Cardiomyocytes | Gene expression | Calcium channels (T-type) | Medicine | Reactivity | Immunofluorescence
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13. Full Text Abnormal fetal cerebral and vascular development in hypoplastic left heart syndrome
by Kinnear, Caroline and Haranal, Maruti and Shannon, Patrick and Jaeggi, Edgar and Chitayat, David and Mital, Seema
Prenatal Diagnosis, ISSN 0197-3851, 01/2019, Volume 39, Issue 1, pp. 38 - 44
Objective To assess the cerebral and vascular development in fetuses with hypoplastic left heart syndrome (HLHS). Methods Pregnant women carrying fetuses... 
SURGERY | IN-UTERO | TETRALOGY | CEREBROVASCULAR BLOOD-FLOW | POLYMORPHISMS | DISEASE | GROWTH | GENETICS & HEREDITY | INJURY | FETUSES | NEURODEVELOPMENTAL DELAY | OBSTETRICS & GYNECOLOGY | Immunohistochemistry | Brain - embryology | Echocardiography | Pulsatile Flow | Humans | Fetal Diseases | Hypoplastic Left Heart Syndrome - physiopathology | Brain - abnormalities | Middle Cerebral Artery - embryology | Gestational Age | Blood Vessels - embryology | Pregnancy | Hypoplastic Left Heart Syndrome - embryology | Ultrasonography, Prenatal | Brain - pathology | Female | Capillaries - embryology | Fetal Heart | Heart | Brain | Fetuses | Abnormalities | Gestation | Disease control | Coronary artery disease | Gestational age | Blood flow | Aorta | Differentiation | Capillaries | Fibroblast growth factor receptor 1 | Heart diseases | Original
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14. Full Text Prolongation of the atrioventricular conduction in fetuses exposed to maternal Anti-Ro/SSA and Anti-La/SSB antibodies did not predict progressive heart block: A prospective observational study on the effects of maternal antibodies on 165 fetuses
by Jaeggi, Edgar T and Silverman, Earl D and Laskin, Carl and Kingdom, John and Golding, Fraser and Weber, Roland
Journal of the American College of Cardiology, ISSN 0735-1097, 03/2011, Volume 57, Issue 13, pp. 1487 - 1492
Objectives: We prospectively examined the prevalence and outcome of untreated fetal atrioventricular (AV) prolongation in the presence of maternal anti-Ro... 
heart block | treatment | lupus erythematosus | fetus | echocardiography | DIAGNOSIS | PR INTERVAL | CARDIAC & CARDIOVASCULAR SYSTEMS | DOPPLER | Echocardiography | Prospective Studies | Humans | Atrioventricular Block - immunology | Pregnancy | Antibodies, Antinuclear - blood | Sensitivity and Specificity | Electrocardiography | Female | Ultrasonography, Doppler, Pulsed | Atrioventricular Block - congenital | Atrioventricular Block - diagnosis | Atrioventricular Node - physiopathology | Heart | Cardiac arrhythmia | Ultrasonic imaging | Fetuses | Coronary vessels | Age
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15. Full Text Impact of prenatal diagnosis on the management and early outcome of critical duct-dependent cardiac lesions
by Thakur, Varsha and Dutil, Nathalie and Schwartz, Steven M and Jaeggi, Edgar
Cardiology in the Young, ISSN 1047-9511, 04/2018, Volume 28, Issue 4, pp. 548 - 553
Objective The objective of this study was to compare the preoperative management and outcome of neonates with duct-dependent critical CHD with fetal versus... 
Fetal | CHD | outcome | echocardiography | cardiac | MORTALITY | CARDIAC & CARDIOVASCULAR SYSTEMS | GREAT-ARTERIES | CLINICAL PRESENTATION | LEFT-HEART SYNDROME | PEDIATRICS | TRANSPOSITION | Heart | Surgical outcomes | Neonates | Pulmonary arteries | Mortality | Fetuses | Medical instruments | Birth | Gestational age | Childbirth & labor | Prenatal diagnosis | Motivation | Consent | Vasoactive agents | Surgery | Ventilation | Birth weight | Diagnosis | Lesions | Heart diseases | Age | Veins & arteries
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16. Full Text Serial echocardiography for immune‐mediated heart disease in the fetus: results of a risk‐based prospective surveillance strategy
by Kan, Nobuhiko and Silverman, Earl D and Kingdom, John and Dutil, Nathalie and Laskin, Carl and Jaeggi, Edgar
Prenatal Diagnosis, ISSN 0197-3851, 04/2017, Volume 37, Issue 4, pp. 375 - 382
Objective Mothers carrying anti‐Ro antibodies are frequently referred for weekly echocardiograms to early detect and treat antibody‐mediated fetal heart... 
MOTHERS | SSA/RO-SSB/LA ANTIBODIES | ANTI-LA ANTIBODIES | PR INTERVAL | GENETICS & HEREDITY | NEONATAL LUPUS-ERYTHEMATOSUS | ET-AL | ATRIOVENTRICULAR-BLOCK | INFANTS BORN | QT INTERVAL | RO/SSA ANTIBODIES | OBSTETRICS & GYNECOLOGY | Fetal Diseases - drug therapy | Heart Block - drug therapy | Fetal Diseases - diagnosis | Endocardial Fibroelastosis - drug therapy | Humans | Risk Factors | Echocardiography - methods | Endocardial Fibroelastosis - diagnosis | Immune System Diseases - drug therapy | Heart Diseases - congenital | Heart Block - diagnosis | Immune System Diseases - diagnosis | Heart Diseases - diagnosis | Pregnancy | Young Adult | Immune System Diseases - congenital | Fetal Monitoring - methods | Adult | Female | Ultrasonography, Prenatal - methods | Heart Block - congenital | Heart Diseases - drug therapy | Retrospective Studies | Immunologic Factors - therapeutic use | Viral antibodies | Antibodies | Corticosteroids | Echocardiography | Pregnant women | Heart diseases | Heart | Cardiovascular disease | Immunoglobulins | Surveillance
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