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Nature Medicine, ISSN 1078-8956, 11/2013, Volume 19, Issue 11, pp. 1410 - 1422
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2014, Volume 111, Issue 8, pp. 3128 - 3133
Journal Article
Cell Cycle, ISSN 1538-4101, 09/2010, Volume 9, Issue 17, pp. 3449 - 3456
Chronic Myeloid Leukemia (CML) is a hematopoietic stem cell malignancy that is driven by the oncogenic BCR-ABL fusion protein, and for which treatment with ABL... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Hedgehog | CML | Leukemic stem cells | BCR-ABL | CHRONIC MYELOGENOUS LEUKEMIA | leukemic stem cells | SONIC HEDGEHOG | ALPHA PLUS CYTARABINE | CANCER STEM-CELLS | CELL BIOLOGY | hedgehog | COMPLETE CYTOGENETIC REMISSION | IMATINIB MESYLATE TREATMENT | TYROSINE KINASE INHIBITOR | cancer | PATIENTS RECEIVING IMATINIB | BASAL-CELL CARCINOMAS
Journal Article
Nature Medicine, ISSN 1078-8956, 12/2010, Volume 16, Issue 12, pp. 1429 - 1433
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 1025 - 1025
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 361 - 361
Journal Article
PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 10, p. e77652
Malignant rhabdoid tumors (MRTs) are aggressive pediatric cancers arising in brain, kidney and soft tissues, which are characterized by loss of the tumor... 
SYNOVIAL SARCOMA | FAMILIAL SCHWANNOMATOSIS | SOFT-TISSUE SARCOMAS | SWI/SNF COMPLEX | CHROMATIN-REMODELING COMPLEX | SUPPRESSOR GENE | MULTIDISCIPLINARY SCIENCES | CELL-CYCLE ARREST | SMARCB1/INI1 PROTEIN | ONCOGENIC TRANSFORMATION | INI1 | Cell Proliferation | Chromosomal Proteins, Non-Histone - metabolism | Humans | Carcinogenesis - genetics | Chromatin Assembly and Disassembly - genetics | Signal Transduction - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Carcinogenesis - metabolism | Promoter Regions, Genetic - genetics | Chromosomal Proteins, Non-Histone - genetics | DNA-Binding Proteins - metabolism | SMARCB1 Protein | Transcription Factors - metabolism | Animals | Rhabdoid Tumor - genetics | Receptors, Fibroblast Growth Factor - metabolism | HEK293 Cells | Receptors, Fibroblast Growth Factor - genetics | Cell Line, Tumor | Mice | Rhabdoid Tumor - metabolism | Fibroblasts - metabolism | Chemotherapy | Chromatin | Genes | Fibroblast growth factors | Gene expression | Health aspects | Tumors | Cancer | Brain | Pediatrics | Fibroblast growth factor | Biomedical research | Syngeneic grafts | Amino acids | Genomes | Remodeling | Kinases | Tissues | Receptors | Cell cycle | Fibroblasts | Growth factors | Fibroblast growth factor receptor 2 | Deoxyribonucleic acid--DNA | Kidneys | Pharmacology | siRNA | Growth factor receptors | Chromatin remodeling | Soft tissues | Signaling | Cell lines | Tumor suppressor genes | Mutation | Receptor mechanisms | Aberration | Kidney transplantation | Fibroblast growth factor receptors | Deoxyribonucleic acid | DNA
Journal Article
by McDonald, E. Robert and de Weck, Antoine and Schlabach, Michael R and Billy, Eric and Mavrakis, Konstantinos J and Hoffman, Gregory R and Belur, Dhiren and Castelletti, Deborah and Frias, Elizabeth and Gampa, Kalyani and Golji, Javad and Kao, Iris and Li, Li and Megel, Philippe and Perkins, Thomas A and Ramadan, Nadire and Ruddy, David A and Silver, Serena J and Sovath, Sosathya and Stump, Mark and Weber, Odile and Widmer, Roland and Yu, Jianjun and Yu, Kristine and Yue, Yingzi and Abramowski, Dorothee and Ackley, Elizabeth and Barrett, Rosemary and Berger, Joel and Bernard, Julie L and Billig, Rebecca and Brachmann, Saskia M and Buxton, Frank and Caothien, Roger and Caushi, Justina X and Chung, Franklin S and Cortés-Cros, Marta and deBeaumont, Rosalie S and Delaunay, Clara and Desplat, Aurore and Duong, William and Dwoske, Donald A and Eldridge, Richard S and Farsidjani, Ali and Feng, JiaJia and Feng, Fei and Flemming, Daisy and Forrester, William and Galli, Giorgio G and Gao, Zhenhai and Gauter, François and Gibaja, Veronica and Haas, Kristy and Hattenberger, Marc and Hood, Tami and Hurov, Kristen E and Jagani, Zainab and Jenal, Mathias and Johnson, Jennifer A and Jones, Michael D and Kapoor, Avnish and Korn, Joshua and Liu, Jilin and Liu, Shumei and Liu, Qiumei and Liu, Yue and Loo, Alice T and Macchi, Kaitlin J and Martin, Typhaine and McAllister, Gregory and Meyer, Amandine and Mollé, Sandra and Pagliarini, Raymond A and Phadke, Tanushree and Repko, Brian and Schouwey, Tanja and Shanahan, Frances and Shen, Qiong and Stamm, Christelle and Stephan, Christine and Stucke, Volker M and Tiedt, Ralph and Varadarajan, Malini and Venkatesan, Kavitha and Vitari, Alberto C and Wallroth, Marco and Weiler, Jan and Zhang, Jing and Mickanin, Craig and Myer, Vic E and Porter, Jeffery A and Lai, Albert and Bitter, Hans and Lees, Emma and Keen, Nicholas and Kauffmann, Audrey and Stegmeier, Frank and Hofmann, Francesco and Schmelzle, Tobias and Sellers, William R
Cell, ISSN 0092-8674, 07/2017, Volume 170, Issue 3, pp. 577 - 592.e10
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 01/2019, Volume 508, Issue 1, pp. 109 - 116
Recent studies have highlighted that cancer cells with a loss of the SWI/SNF complex catalytic subunit are dependent on the remaining ATPase, making it an... 
SMASh | Degron | BRM/SMARCA2 | SWI/SNF | BRG1/SMARCA4 | MCL1 | TARGET | BIOPHYSICS | SWI/SNF COMPLEXES | BIOCHEMISTRY & MOLECULAR BIOLOGY | INHIBITOR
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