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1. Full Text Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations
by Bueno, Raphael and Stawiski, Eric W and Goldstein, Leonard D and Durinck, Steffen and De Rienzo, Assunta and Modrusan, Zora and Gnad, Florian and Nguyen, Thong T and Jaiswal, Bijay S and Chirieac, Lucian R and Sciaranghella, Daniele and Dao, Nhien and Gustafson, Corinne E and Munir, Kiara J and Hackney, Jason A and Chaudhuri, Amitabha and Gupta, Ravi and Guillory, Joseph and Toy, Karen and Ha, Connie and Chen, Ying-Jiun and Stinson, Jeremy and Chaudhuri, Subhra and Zhang, Na and Wu, Thomas D and Sugarbaker, David J and De Sauvage, Frederic J and Richards, William G and Seshagiri, Somasekar
Nature genetics, ISSN 1061-4036, 03/2016, Volume 48, Issue 4, pp. 407 - 416
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Oncogene Proteins, Fusion - metabolism | Pleural Neoplasms - genetics | Alternative Splicing | Lung Neoplasms - mortality | Humans | Lung Neoplasms - metabolism | Mesothelioma - mortality | Phosphoproteins - metabolism | Exome | Pleural Neoplasms - metabolism | Ribonucleoprotein, U2 Small Nuclear - metabolism | Protein Isoforms - metabolism | DNA Mutational Analysis | Ribonucleoprotein, U2 Small Nuclear - genetics | Lung Neoplasms - genetics | Kaplan-Meier Estimate | Proportional Hazards Models | RNA Splicing Factors | Mesothelioma - genetics | Phosphoproteins - genetics | Pleural Neoplasms - mortality | Mesothelioma - metabolism | Oncogene Proteins, Fusion - genetics | Cell Line, Tumor | Polymorphism, Single Nucleotide | Mesothelioma, Malignant | Mutation | Protein Isoforms - genetics | Gene mutations | Mesothelioma | Development and progression | Cellular signal transduction | Genetic aspects | Identification and classification | Health aspects | Genomics | Principal components analysis | Genomes | Gene expression | Patients | Studies | Confidence intervals | Womens health | Medical prognosis | Classification | Bioinformatics | Index Medicus
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2. Full Text RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth
by Hatzivassiliou, Georgia and Song, Kyung and Yen, Ivana and Brandhuber, Barbara J and Anderson, Daniel J and Alvarado, Ryan and Ludlam, Mary J. C and Stokoe, David and Gloor, Susan L and Vigers, Guy and Morales, Tony and Aliagas, Ignacio and Liu, Bonnie and Sideris, Steve and Hoeflich, Klaus P and Jaiswal, Bijay S and Seshagiri, Somasekar and Koeppen, Hartmut and Belvin, Marcia and Friedman, Lori S and Malek, Shiva
Nature (London), ISSN 0028-0836, 03/2010, Volume 464, Issue 7287, pp. 431 - 435
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | General aspects | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Animal tumors. Experimental tumors | Experimental tumors, general aspects | Antineoplastic agents | Tumors | Neoplasms - metabolism | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Diphenylamine - pharmacology | raf Kinases - antagonists & inhibitors | Humans | Protein Multimerization | ras Proteins - metabolism | Protein Transport - drug effects | Extracellular Signal-Regulated MAP Kinases - metabolism | raf Kinases - metabolism | Diphenylamine - analogs & derivatives | Mitogen-Activated Protein Kinase Kinases - metabolism | Adenosine Triphosphate - metabolism | Indoles - pharmacology | Benzamides - pharmacology | Cell Membrane - metabolism | raf Kinases - genetics | Cell Membrane - drug effects | Proto-Oncogene Proteins B-raf - metabolism | Proto-Oncogene Proteins B-raf - chemistry | Pyrazoles - pharmacology | Protein Structure, Tertiary | Proto-Oncogene Proteins - metabolism | Cell Line | Indenes - pharmacology | raf Kinases - chemistry | Proto-Oncogene Proteins c-raf - genetics | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Neoplasms - enzymology | Proto-Oncogene Proteins - genetics | Enzyme Activation - drug effects | Sulfonamides - pharmacology | Proto-Oncogene Proteins c-raf - metabolism | Neoplasms - drug therapy | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | MAP Kinase Signaling System - drug effects | Protein Kinase Inhibitors - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Proto-Oncogene Proteins c-raf - deficiency | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Neoplasms - pathology | Ras genes | Growth | Physiological aspects | Cellular signal transduction | Genetic aspects | Research | Mitogen-activated protein kinases | Competition | Clinical trials | Enzymes | Kinases | Index Medicus | Proteins | Cellular | Inhibitors | Pathways | Tumours | Signalling | Dimerization
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3. Full Text Recurrent R-spondin fusions in colon cancer
by Seshagiri, Somasekar and Stawiski, Eric W and Durinck, Steffen and Modrusan, Zora and Storm, Elaine E and Conboy, Caitlin B and Chaudhuri, Subhra and Guan, Yinghui and Janakiraman, Vasantharajan and Jaiswal, Bijay S and Guillory, Joseph and Ha, Connie and Dijkgraaf, Gerrit J. P and Stinson, Jeremy and Gnad, Florian and Huntley, Melanie A and Degenhardt, Jeremiah D and Haverty, Peter M and Bourgon, Richard and Wang, Weiru and Koeppen, Hartmut and Gentleman, Robert and Starr, Timothy K and Zhang, Zemin and Largaespada, David A and Wu, Thomas D and De Sauvage, Frederic J
Nature (London), ISSN 0028-0836, 08/2012, Volume 488, Issue 7413, pp. 660 - 664
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Biological and medical sciences | Medical sciences | Tumors | Colonic Neoplasms - genetics | Thrombospondins - genetics | Humans | Molecular Sequence Data | Gene Expression Profiling | Wnt Proteins - metabolism | Colonic Neoplasms - metabolism | Genes, APC | Insulin-Like Growth Factor II - genetics | Base Sequence | Tumor Suppressor Proteins - genetics | Cell Cycle Proteins - genetics | Genes, Neoplasm - genetics | Gene Expression Regulation, Neoplastic - genetics | Transcription Factor 7-Like 2 Protein - genetics | Intercellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - genetics | Proto-Oncogene Proteins - genetics | DNA Copy Number Variations - genetics | Signal Transduction - genetics | Ataxia Telangiectasia Mutated Proteins | Receptor, ErbB-3 - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Gene Fusion - genetics | Exome - genetics | Dioxygenases - genetics | Sequence Analysis, RNA | Colonic Neoplasms - pathology | Polymorphism, Single Nucleotide - genetics | Care and treatment | Colon cancer | Gene mutations | Genomics | Patient outcomes | Genetic aspects | Research | Proteins | Mutation | Colon | Genes | Index Medicus
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4. Full Text Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
by Rudin, Charles M and Durinck, Steffen and Stawiski, Eric W and Poirier, John T and Modrusan, Zora and Shames, David S and Bergbower, Emily A and Guan, Yinghui and Shin, James and Guillory, Joseph and Rivers, Celina Sanchez and Foo, Catherine K and Bhatt, Deepali and Stinson, Jeremy and Gnad, Florian and Haverty, Peter M and Gentleman, Robert and Chaudhuri, Subhra and Janakiraman, Vasantharajan and Jaiswal, Bijay S and Parikh, Chaitali and Yuan, Wenlin and Zhang, Zemin and Koeppen, Hartmut and Wu, Thomas D and Stern, Howard M and Yauch, Robert L and Huffman, Kenneth E and Paskulin, Diego D and Illei, Peter B and Varella-Garcia, Marileila and Gazdar, Adi F and De Sauvage, Frederic J and Bourgon, Richard and Minna, John D and Brock, Malcolm V and Seshagiri, Somasekar
Nature genetics, ISSN 1061-4036, 10/2012, Volume 44, Issue 10, pp. 1111 - 1116
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Diverse techniques | Molecular and cellular biology | Genetics of eukaryotes. Biological and molecular evolution | Lung Neoplasms - genetics | Gene Expression | Genome-Wide Association Study | Protein Kinases - genetics | Humans | Lung Neoplasms - metabolism | Molecular Sequence Data | Small Cell Lung Carcinoma - genetics | DNA Copy Number Variations | SOXB1 Transcription Factors - metabolism | Exome | Small Cell Lung Carcinoma - metabolism | Gene Amplification | SOXB1 Transcription Factors - genetics | DNA Mutational Analysis | Oncogene Proteins, Fusion - genetics | Base Sequence | Cell Line, Tumor | High-Throughput Nucleotide Sequencing | Mutation | Physiological aspects | Lung cancer, Small cell | Genetic aspects | Research | Gene mutations | Protein kinases | Proteins | Genomes | Bioinformatics | Genes | Index Medicus
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5. Full Text Diverse somatic mutation patterns and pathway alterations in human cancers
by Kan, Zhengyan and Jaiswal, Bijay S and Stinson, Jeremy and Janakiraman, Vasantharajan and Bhatt, Deepali and Stern, Howard M and Yue, Peng and Haverty, Peter M and Bourgon, Richard and Zheng, Jianbiao and Moorhead, Martin and Chaudhuri, Subhra and Tomsho, Lynn P and Peters, Brock A and Pujara, Kanan and Cordes, Shaun and Davis, David P and Carlton, Victoria E. H and Yuan, Wenlin and Li, Li and Wang, Weiru and Eigenbrot, Charles and Kaminker, Joshua S and Eberhard, David A and Waring, Paul and Schuster, Stephan C and Modrusan, Zora and Zhang, Zemin and Stokoe, David and De Sauvage, Frederic J and Faham, Malek and Seshagiri, Somasekar
Nature (London), ISSN 0028-0836, 08/2010, Volume 466, Issue 7308, pp. 869 - 873
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Biological and medical sciences | General aspects | Carcinogenesis, carcinogens and anticarcinogens | Medical sciences | Tumors | Breast Neoplasms - classification | Lung Neoplasms - genetics | Neoplasms - metabolism | Protein Kinases - genetics | Humans | Neoplasms - enzymology | GTP-Binding Protein alpha Subunits - genetics | Male | DNA Copy Number Variations - genetics | Signal Transduction - genetics | Mutation - genetics | Ovarian Neoplasms - genetics | Lung Neoplasms - classification | Ovarian Neoplasms - classification | Breast Neoplasms - genetics | Prostatic Neoplasms - genetics | Neoplasms - genetics | DNA Mutational Analysis | Prostatic Neoplasms - classification | MAP Kinase Kinase 4 - genetics | Female | Receptors, G-Protein-Coupled - genetics | Neoplasms - pathology | Genes, Neoplasm - genetics | Care and treatment | Gene mutations | Physiological aspects | Genetic aspects | Cellular signal transduction | Research | Health aspects | Protein kinases | Cancer | Studies | Mutation | Mass spectrometry | Deoxyribonucleic acid--DNA | Index Medicus
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6. Full Text Oncogenic ERBB3 Mutations in Human Cancers
by Jaiswal, Bijay S and Kljavin, Noelyn M and Stawiski, Eric W and Chan, Emily and Parikh, Chaitali and Durinck, Steffen and Chaudhuri, Subhra and Pujara, Kanan and Guillory, Joseph and Edgar, Kyle A and Janakiraman, Vasantharajan and Scholz, Rolf-Peter and Bowman, Krista K and Lorenzo, Maria and Li, Hong and Wu, Jiansheng and Yuan, Wenlin and Peters, Brock A and Kan, Zhengyan and Stinson, Jeremy and Mak, Michelle and Modrusan, Zora and Eigenbrot, Charles and Firestein, Ron and Stern, Howard M and Rajalingam, Krishnaraj and Schaefer, Gabriele and Merchant, Mark A and Sliwkowski, Mark X and de Sauvage, Frederic J and Seshagiri, Somasekar
Cancer cell, ISSN 1535-6108, 05/2013, Volume 23, Issue 5, pp. 603 - 617
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Protein Structure, Tertiary | Stomach Neoplasms - genetics | Colonic Neoplasms - genetics | Receptor, ErbB-3 - metabolism | Cell Proliferation | Humans | Cell Survival - genetics | Models, Molecular | Receptor, ErbB-3 - genetics | Gene Knockdown Techniques | Receptor, ErbB-3 - physiology | Cell Transformation, Neoplastic - genetics | Mutation | Binding Sites | Genetic research | Development and progression | Genetic aspects | Epidermal growth factor | Phosphotransferases | Cancer | Index Medicus
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7. Full Text Massively parallel nanowell-based single-cell gene expression profiling
by Goldstein, Leonard D and Chen, Ying-Jiun Jasmine and Dunne, Jude and Mir, Alain and Hubschle, Hermann and Guillory, Joseph and Yuan, Wenlin and Zhang, Jingli and Stinson, Jeremy and Jaiswal, Bijay and Pahuja, Kanika Bajaj and Mann, Ishminder and Schaal, Thomas and Chan, Leo and Anandakrishnan, Sangeetha and Lin, Chun-wah and Espinoza, Patricio and Husain, Syed and Shapiro, Harris and Swaminathan, Karthikeyan and Wei, Sherry and Srinivasan, Maithreyan and Seshagiri, Somasekar and Modrusan, Zora
BMC genomics, ISSN 1471-2164, 07/2017, Volume 18, Issue 1, pp. 519 - 519
RNA sequencing | Single-cell transcriptome | Single cell profiling | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Sequence Analysis, RNA - methods | Cell Line | Islets of Langerhans - metabolism | Nanotechnology - methods | Single-Cell Analysis - methods | Humans | Islets of Langerhans - cytology | Gene Expression Profiling - methods | High-Throughput Nucleotide Sequencing - methods | Tissue Array Analysis - methods | Pancreatic beta cells | RNA | Gene expression | Multiprocessing | Bar codes | Biological properties | Profiling | Semiconductors | Oligonucleotides | Genomes | Ribonucleic acid--RNA | Biological samples | Contamination | Gene sequencing | Complexity | Animal tissues | Quality control | Software | Pancreas | Index Medicus
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8. Full Text Surgical treatment of tuberculous chronic constrictive pericarditis: A retrospective observational study from tertiary hospital of eastern Nepal
by Jaiswal, Lokesh Shekher and Pandit, Narendra and Sah, Bijay
Indian journal of tuberculosis, ISSN 0019-5707, 08/2020
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9. Full Text Simple Bone Cyst of Rib
by Jaiswal, Lokesh Shekher and Sah, Bijay and Pandit, Narendra and Karki, Smriti and Adhikary, Shailesh
The Annals of thoracic surgery, ISSN 0003-4975, 07/2019, Volume 108, Issue 1, pp. e39 - e41
Cardiac & Cardiovascular Systems | Respiratory System | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Surgery | Science & Technology | Teenage girls | Index Medicus | Abridged Index Medicus
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