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1. Full Text Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer
by Gudmundsson, J and Sulem, P and Rafnar, T and Bergthorsson, J.T and Manolescu, A and Gudbjartsson, D.F and Agnarsson, B.A and Sigurdsson, A and Benediktsdottir, K.R and Blondal, T and Jakobsdottir, M and Stacey, S.N and Kostic, J and Kristinsson, K.T and Birgisdottir, B and Ghosh, S and Magnusdottir, D and Thorlacius, S and Thorleifsson, G and Zheng, S.L and Sun, J and Chang, B.L and Elmore, J.B and Breyer, J.P and McReynolds, K.M and Bradley, K.M and Yaspan, B.L and Wiklund, F and Stattin, P and Lindstrom, S and Adami, H.O and McDonnell, S.K and Schaid, D.J and Cunningham, J.M and Wang, L and Cerhan, J.R and Sauver, J.L. St and Isaacs, S.D and Wiley, K.E and Partin, A.W and Walsh, P.C and Polo, S and Ruiz-Echarri, M and Navarrete, S and Fuertes, F and Saez, B and Godino, J and Weijerman, P.C and Swinkels, D.W and Aben, K.K.H and Witjes, J.A and Suarez, B.K and Helfand, B.T and Frigge, M.L and Kristjansson, K and Ober, C and Jonsson, E and Einarsson, G.V and Xu, J and Gronberg, H and Smith, J.R and Thibodeau, S.N and Isaacs, W.B and Catalona, W.J and Mayordomo, J.I and Kiemeney, L.A.L.M and Barkardottir, R.B and Gulcher, J.R and Thorsteinsdottir, U and Kong, A and Stefansson, K
Nature genetics, ISSN 1061-4036, 2008, Volume 40, Issue 3, pp. 281 - 283
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Classical genetics, quantitative genetics, hybrids | Tumors of the urinary system | Urinary tract. Prostate gland | Nephrology. Urinary tract diseases | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Methods, theories and miscellaneous | Genetic Predisposition to Disease | Genetic Testing | United States | Gene Frequency | Humans | Male | Case-Control Studies | Iceland | Linkage Disequilibrium | Spain | Chromosomes, Human, Pair 2 | Chromosomes, Human, X | Netherlands | Sweden | Prostatic Neoplasms - genetics | Polymorphism, Single Nucleotide | Physiological aspects | Genetic research | Genetic aspects | Diagnosis | Research | Single nucleotide polymorphisms | Prostate cancer | Identification and classification | Risk factors | Methods | Genetic markers | Genomics | Index Medicus | Medicin och hälsovetenskap
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2. Full Text Sequence variants at the TERT-CLPTM1L locus associate with many cancer types
by Rafnar, T and Sulem, P and Stacey, S.N and Geller, F and Gudmundsson, J and Sigurdsson, A and Jakobsdottir, M and Helgadottir, H and Thorlacius, S and Aben, K.K.H and Blondal, T and Thorgeirsson, T.E and Thorleifsson, G and Kristjansson, K and Thorisdottir, K and Ragnarsson, R and Sigurgeirsson, B and Skuladottir, H and Gudbjartsson, T and Isaksson, H.J and Einarsson, G.V and Benediktsdottir, K.R and Agnarsson, B.A and Olafsson, K and Salvarsdottir, A and Bjarnason, H and Asgeirsdottir, M and Kristinsson, K.T and Matthiasdottir, S and Sveinsdottir, S.G and Polidoro, S and Hoiom, V and Botella-Estrada, R and Hemminki, K and Rudnai, P and Bishop, D.T and Campagna, M and Kellen, E and Zeegers, M.P and Verdier, P. de and Ferrer, A and Isla, D and Vidal, M.J and Anes, R and Saez, B and Juberias, P and Banzo, J and Navarrete, S and Tres, A and Kan, D and Lindblom, A and Gurzau, E and Koppova, K and Vegt, F. de and Schalken, J.A and Heijden, H.F.M. van der and Smit, H.J and Termeer, R.A and Oosterwijk, E and Hooij, O. van and Nagore, E and Porru, S and Steineck, G and Hansson, J and Buntinx, F and Catalona, W.J and Matullo, G and Vineis, P and Kiltie, A.E and Mayordomo, J.I and Kumar, R and Kiemeney, L.A.L.M and Frigge, M.L and Jonsson, T and Saemundsson, H and Barkardottir, R.B and Jonsson, E and Jonsson, S and Olafsson, J.H and Gulcher, J.R and Masson, G and Gudbjartsson, D.F and Kong, A and Thorsteinsdottir, U and Stefansson, K
Nature genetics, ISSN 1061-4036, 2009, Volume 41, Issue 2, pp. 221 - 227
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Genetic Predisposition to Disease | Genome-Wide Association Study | Carcinoma, Basal Cell - genetics | Membrane Proteins - genetics | Gene Frequency | Humans | Middle Aged | Polymorphism, Single Nucleotide - physiology | Male | Case-Control Studies | Linkage Disequilibrium | Telomerase - genetics | Neoplasms - genetics | Skin Neoplasms - genetics | Female | Aged | Neoplasm Proteins - genetics | Quantitative Trait Loci | Gene mutations | Genetic aspects | Research | Single nucleotide polymorphisms | Health aspects | Risk factors | Cancer | Medical research | Sample size | Prostate cancer | Cervical cancer | Colorectal cancer | Index Medicus | Medicin och hälsovetenskap
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3. Full Text Exome-wide association study of plasma lipids in >300,000 individuals
by Liu, Dajiang J and Peloso, Gina M and Yu, Haojie and Butterworth, Adam S and Wang, Xiao and Mahajan, Anubha and Saleheen, Danish and Emdin, Connor and Alam, Dewan and Alves, Alexessander Couto and Amouyel, Philippe and Di Angelantonio, Emanuele and Arveiler, Dominique and Assimes, Themistocles L and Auer, Paul L and Baber, Usman and Ballantyne, Christie M and Bang, Lia E and Benn, Marianne and Bis, Joshua C and Boehnke, Michael and Boerwinkle, Eric and Bork-Jensen, Jette and Bottinger, Erwin P and Brandslund, Ivan and Brown, Morris and Busonero, Fabio and Caulfield, Mark J and Chambers, John C and Chasman, Daniel I and Chen, Y. Eugene and Chen, Yii-Der Ida and Chowdhury, Rajiv and Christensen, Cramer and Chu, Auey Y and Connell, John M and Cucca, Francesco and Cupples, L. Aienne and Damrauer, Scott M and Davies, Gail and Deary, Ian J and Dedoussis, George and Denny, Joshua C and Dominiczak, Anna and Dubé, Marie-Pierre and Ebeling, Tapani and Eiriksdottir, Gudny and Esko, Tõnu and Farmaki, Aliki-Eleni and Feitosa, Mary F and Ferrario, Marco and Ferrieres, Jean and Ford, Ian and Fornage, Myriam and Franks, Paul W and Frayling, Timothy M and Frikke-Schmidt, Ruth and Fritsche, Lars G and Frossard, Philippe and Fuster, Valentin and Ganesh, Santhi K and Gao, Wei and Garcia, Melissa E and Gieger, Christian and Giulianini, Franco and Goodarzi, Mark O and Grallert, Harald and Grarup, Niels and Groop, Leif and Grove, Megan L and Gudnason, Vilmundur and Hansen, Torben and Harris, Tamara B and Hayward, Caroline and Hirschhorn, Joel N and Holmen, Oddgeir L and Huffman, Jennifer and Huo, Yong and Hveem, Kristian and Jabeen, Sehrish and Jackson, Anne U and Jakobsdottir, Johanna and Jarvelin, Marjo-Riitta and Jensen, Gorm B and Jørgensen, Marit E and Jukema, J. Wouter and Justesen, Johanne M and Kamstrup, Pia R and Kanoni, Stavroula and Karpe, Freik and Kee, Frank and Khera, Amit V and Klarin, Derek and Koistinen, Heikki A and Kooner, Jaspal S and Kooperberg, Charles and Kuulasmaa, Kari and Kuusisto, Johanna and Laakso, Markku and Lakka, Timo and ... and VA Million Veteran Program and Charge Diabet Working Grp and EPIC-CVD Consortium and EPIC-InterAct Consortium and GOLD Consortium and The EPIC-InterAct Consortium and Charge Diabetes Working Group
Nature genetics, ISSN 1061-4036, 2017, Volume 49, Issue 12, pp. 1758 - 1766
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genotype | Genome-wide association studies | Genetic aspects | Blood lipids | Identification and classification | Methods | Plasma | Lipoproteins (low density) | Liver | Lipids | Risk | Cardiovascular disease | Genomes | Macular degeneration | Consortia | Janus kinase 2 | Heart diseases | Lipoproteins (high density) | Age | Diabetes mellitus | Coronary artery | Health risks | Thalassemia | Triglycerides | Coronary artery disease | Loci | Cholesterol | Lipolysis | Studies | Lipoproteins | Genotyping | Alleles | Quality control | Diabetes | Index Medicus
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4. Full Text Genetic variants near TIMP3 and high-density lipoprotein—associated loci influence susceptibility to age-related macular degeneration
by Wei Chen and Dwight Stambolian and Albert O. Edwards and Kari E. Branham and Mohammad Othman and Johanna Jakobsdottir and Nirubol Tosakulwong and Margaret A. Pericak-Vance and Peter A. Campochiaro and Michael L. Klein and Perciliz L. Tan and Yvette P. Conley and Atsuhiro Kanda and Laura Kopplin and Yanming Li and Katherine J. Augustaitis and Athanasios J. Karoukis and William K. Scott and Anita Agarwal and Jaclyn L. Kovach and Stephen G. Schwartz and Eric A. Postel and Matthew Brooks and Keith H. Baratz and William L. Brown and Complications of Age-Related Macular Degeneration Prevention Trial (CAPT) Research Group and Alexander J. Brucker and Anton Orlin and Gary Brown and Allen Ho and Carl Regillo and Larry Donoso and Lifeng Tian and Brian Kaderli and Dexter Hadley and Stephanie A. Hagstrom and Neal S. Peachey and Ronald Klein and Barbara E. K. Klein and Norimoto Gotoh and Kenji Yamashiro and Frederick Ferris and Jesen A. Fagerness and Robyn Reynolds and Lindsay A. Farrer and Ivana K. Kim and Joan W. Miller and Marta Cortón and Angel Carracedo and Manuel Sanchez-Salorio and Elizabeth W. Pugh and Kimberly F. Doheny and Maria Brion and Margaret M. DeAngelis and Daniel E. Weeks and Donald J. Zack and Emily Y. Chew and John R. Heckenlively and Nagahisa Yoshimura and Sudha K. Iyengar and Peter J. Francis and Nicholas Katsanis and Johanna M. Seddon and Jonathan L. Haines and Michael B. Gorin and Gonçalo R. Abecasis and Anand Swaroop and Mark T. Keating and Complications Age-Related Macular and Complications of Age-Related Macular Degeneration Prevention Trial Research Group and Complications of Age-Related Macular Degeneration Prevention Trial (CAPT) Research Group
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 4/2010, Volume 107, Issue 16, pp. 7401 - 7406
Macular degeneration | Drusen | Genes | Alleles | Disease risk | Genetic loci | P values | Disease susceptibility | Chromosomes | Genotypes | Genome-wide association study | Single nucleotide polymorphism | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | Lipoproteins, HDL - metabolism | Complement Factor I - genetics | Genotype | Risk | Chromosome Mapping | Tissue Inhibitor of Metalloproteinase-3 - physiology | Case-Control Studies | Genetic Variation | Regression Analysis | Macular Degeneration - genetics | Polymorphism, Single Nucleotide | Tissue Inhibitor of Metalloproteinase-3 - genetics | Genetic susceptibility | High density lipoproteins | Physiological aspects | Genetic aspects | Single nucleotide polymorphisms | Properties | Identification and classification | Risk factors | Studies | Genotype & phenotype | Enzymes | Lipoproteins | Pathogenesis | Genetics | Comparative analysis | Index Medicus | Biological Sciences | single nucleotide polymorphism | genome-wide association study
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5. Full Text Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels
by Tin, Aienne and Marten, Jonathan and Halperin Kuhns, Victoria L and Li, Yong and Wuttke, Matthias and Kirsten, Holger and Sieber, Karsten B and Qiu, Chengxiang and Gorski, Mathias and Yu, Zhi and Giri, Ayush and Sveinbjornsson, Gardar and Li, Man and Chu, Auey Y and Hoppmann, Anselm and O'Connor, Luke J and Prins, Bram and Nutile, Teresa and Noce, Damia and Akiyama, Masato and Cocca, Massimiliano and Ghasemi, Sahar and van der Most, Peter J and Horn, Katrin and Xu, Yizhe and Fuchsberger, Christian and Sedaghat, Sanaz and Afaq, Saima and Amin, Najaf and Ärnlöv, Johan and Bakker, Stephan J L and Bansal, Nisha and Baptista, Daniela and Bergmann, Sven and Biggs, Mary L and Biino, Ginevra and Boerwinkle, Eric and Bottinger, Erwin P and Boutin, Thibaud S and Brumat, Marco and de Borst, Martin H and de Vries, Aiko P J and Gansevoort, Ron T and Huang, Wei and Nolte, Ilja M and Penninx, Brenda W J H and Smith, Albert V and van der Harst, Pim and Verweij, Niek and Snieder, Harold and VA Million Vet Program and German Chronic Kidney Dis Study and Lifelines Cohort Study and V. A. Million Veteran Program and German Chronic Kidney Disease Study
Nature genetics, ISSN 1061-4036, 10/2019, Volume 51, Issue 10, pp. 1459 - 1474
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Liver - pathology | Hepatocyte Nuclear Factor 1-alpha - genetics | Kidney - pathology | Humans | Genetic Loci | Cardiovascular Diseases - genetics | Kidney - metabolism | Gout - epidemiology | Cardiovascular Diseases - blood | Cardiovascular Diseases - epidemiology | Uric Acid - blood | Gout - blood | Neoplasm Proteins - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Signal Transduction | Liver - metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 2 - genetics | Metabolic Diseases - epidemiology | Metabolic Diseases - blood | Hepatocyte Nuclear Factor 4 - genetics | Genetic Markers | Organ Specificity | Metabolic Diseases - genetics | Gout - genetics | Polymorphism, Single Nucleotide | Cohort Studies | Medical colleges | Analysis | Liver | Genomics | Genes | Genetic research | Genetic aspects | Genomes | Genetic transcription | Regulators | Transcription factors | Transcription | Gout | African Americans | Mapping | Databases | Genetic analysis | Population | Rheumatism | Hepatocyte nuclear factor 4 | Bioinformatics | Kidneys | Organs | Uric acid | Metabolism | Gene expression | Loci | Meta-analysis | Studies | Pleiotropy | Gene loci | Gene mapping | Transporter | Binding sites | Open access | Index Medicus | Medicin och hälsovetenskap
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6. Full Text A catalog of genetic loci associated with kidney function from analyses of a million individuals
by Wuttke, Matthias and Li, Yong and Li, Man and Sieber, Karsten B and Feitosa, Mary F and Gorski, Mathias and Tin, Aienne and Wang, Lihua and Chu, Auey Y and Hoppmann, Anselm and Kirsten, Holger and Giri, Ayush and Chai, Jin-Fang and Sveinbjornsson, Gardar and Tayo, Bamidele O and Nutile, Teresa and Fuchsberger, Christian and Marten, Jonathan and Cocca, Massimiliano and Ghasemi, Sahar and Xu, Yizhe and Horn, Katrin and Noce, Damia and van der Most, Peter J and Sedaghat, Sanaz and Yu, Zhi and Akiyama, Masato and Afaq, Saima and Ahluwalia, Tarunveer S and Almgren, Peter and Amin, Najaf and Ärnlöv, Johan and Bakker, Stephan J. L and Bansal, Nisha and Baptista, Daniela and Bergmann, Sven and Biggs, Mary L and Biino, Ginevra and Boehnke, Michael and Boerwinkle, Eric and Boissel, Mathilde and Bottinger, Erwin P and Boutin, Thibaud S and Brenner, Hermann and Brumat, Marco and Burkhardt, Ralph and Butterworth, Adam S and Campana, Eric and Milaneschi, Yuri and Penninx, Brenda W. J. H and Köttgen, Anna and Pattaro, Cristian
Nature genetics, ISSN 1061-4036, 06/2019, Volume 51, Issue 6, pp. 957 - 972
c_article_only_freely_accessible_via_repository | yes | Medicin och hälsovetenskap
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7. Full Text PLD3 variants in population studies
by Lee, Sven and Holstege, Henne and Wong, Terence H and Jakobsdottir, Margret and Bis, Joshua and Chouraki, Vincent and Van Rooij, Jeroen and Grove, Megan and Smith, Davey and Amin, Najaf and Choi, Seung-Hoan and Beiser, Alexa and Garcia, Melissa and IJcken, Wilfred and Pijnenburg, Yolande and Louwersheimer, Eva and Brouwer, Rutger and van den hout, Mirjam and Oole, Edwin and Eirkisdottir, Gudny and Levy, Daniel and Rotter, Jerome I and Emilsson, Valur and O'Donnell, Christopher and Aspelund, Thor and Uitterlinden, Ané and Launer, Lenore and Hofman, Albert and Boerwinkle, Eric and Psaty, Bruce and DeStefano, Anita and Scheltens, Philip and Seshai, Sudha and Swieten, John and Gudnason, Vilmundur and Flier, Wiesje and Ikram, Arfan and Duijn, Cornelia
Nature (London), ISSN 0028-0836, 04/2015, Volume 520, Issue 7545, pp. E2 - E3
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genetic Predisposition to Disease - genetics | Humans | Female | Male | Genetic Variation - genetics | Phospholipase D - genetics | Alzheimer Disease - genetics | Genetic variation | Distribution | Genetic aspects | Phospholipases | Identification and classification | Alzheimer's disease | Health aspects | Risk factors | Studies | Genomes | Medical imaging | Alzheimers disease | Genes | Age | Index Medicus
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8. Full Text Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks
by Peloso, Gina M and Auer, Paul L and Bis, Joshua C and Voorman, Arend and Morrison, Alanna C and Stitziel, Nathan O and Brody, Jennifer A and Khetarpal, Sumeet A and Crosby, Jacy R and Fornage, Myriam and Isaacs, Aaron and Jakobsdottir, Johanna and Feitosa, Mary F and Davies, Gail and Huffman, Jennifer E and Manichaikul, Ani and Davis, Brian and Lohman, Kurt and Joon, Aron Y and Smith, Albert V and Grove, Megan L and Zanoni, Paolo and Redon, Valeska and Demissie, Serkalem and Lawson, Kim and Peters, Ulrike and Carlson, Christopher and Jackson, Rebecca D and Ryckman, Kelli K and Mackey, Rachel H and Robinson, Jennifer G and Siscovick, David S and Schreiner, Pamela J and Mychaleckyj, Josyf C and Pankow, James S and Hofman, Albert and Uitterlinden, Andre G and Harris, Tamara B and Taylor, Kent D and Stafford, Jeanette M and Reynolds, Lindsay M and Marioni, Riccardo E and Dehghan, Abbas and Franco, Oscar H and Patel, Aniruddh P and Lu, Yingchang and Hindy, George and Gottesman, Omri and Bottinger, Erwin P and Melander, Olle and Orho-Melander, Marju and Loos, Ruth J.F and Duga, Stefano and Merlini, Piera Angelica and Farrall, Martin and Goel, Anuj and Asselta, Rosanna and Girelli, Domenico and Martinelli, Nicola and Shah, Svati H and Kraus, William E and Li, Mingyao and Rader, Daniel J and Reilly, Muredach P and McPherson, Ruth and Watkins, Hugh and Ardissino, Diego and Zhang, Qunyuan and Wang, Judy and Tsai, Michael Y and Taylor, Herman A and Correa, Adolfo and Griswold, Michael E and Lange, Leslie A and Starr, John M and Rudan, Igor and Eiriksdottir, Gudny and Launer, Lenore J and Ordovas, Jose M and Levy, Daniel and Chen, Y.-D. Ida and Reiner, Alexander P and Hayward, Caroline and Polasek, Ozren and Deary, Ian J and Borecki, Ingrid B and Liu, Yongmei and Gudnason, Vilmundur and Wilson, James G and van Duijn, Cornelia M and Kooperberg, Charles and Rich, Stephen S and Psaty, Bruce M and Rotter, Jerome I and O’Donnell, Christopher J and Rice, Kenneth and Boerwinkle, Eric and Kathiresan, Sekar and Cupples, L. Adrienne and NHLBI GO Exome Sequencing Project
American journal of human genetics, ISSN 0002-9297, 02/2014, Volume 94, Issue 2, pp. 223 - 232
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Code | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Middle Aged | Male | Genetic Variation | 1-Alkyl-2-acetylglycerophosphocholine Esterase - genetics | Adult | Cholesterol, LDL - blood | Female | Subtilisins - metabolism | African Continental Ancestry Group - genetics | Coronary Disease - blood | European Continental Ancestry Group - genetics | Genetic Association Studies | Gene Frequency | Mice, Inbred C57BL | Linear Models | Cholesterol, HDL - genetics | Sequence Analysis, DNA | 1-Alkyl-2-acetylglycerophosphocholine Esterase - metabolism | Cholesterol, LDL - genetics | Phenotype | Animals | Coronary Disease - genetics | Alleles | Triglycerides - blood | Cholesterol, HDL - blood | Subtilisins - genetics | Aged | Mice | Cohort Studies | Genetic code | Genetic variation | Physiological aspects | Genetic research | Genetic aspects | Research | Coronary heart disease | Population genetics | Lipids | Cardiovascular disease | Low density lipoprotein | Risk assessment | Deoxyribonucleic acid--DNA | Index Medicus | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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