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1. Full Text Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci
by Liu, C and Kraja, Aldi and Smith, Jennifer A and Brody, Jennifer and Franceschini, Nora and Bis, Joshua and Rice, Kenneth and Morrison, Alanna and Lu, Yingchang and Weiss, S and Guo, Xiuqing and Palmas, Walter and Martin, Lisa and Chen, Y and Surenan, P and nos, Fotios and Cook, J.P and Auer, Paul and Chu, Auey and Giri, A and Zhao, W and Jakobsdottir, Margret and Lin, L.-A and Stafford, Jeanette M and Amin, Najaf and Mei, H and Yao, Jiefen and Voorman, Jeanine and Larson, Martin and Grove, Megan and Smith, Albert Vernon and Hwang, S.J and Chen, Han and Huan, Tianxiao and Kosova, G and Stitziel, Nathan and Kathiresan, Sekar and Samani, Nilesh and Schunkert, Heribert and Deloukas, Panagiotis and Li, Man and Fuchsberger, Christian and Pattaro, Cristian and Gorski, Mathias and Kooperberg, Charles and Papanicolaou, George and Rossouw, J.E and Faul, Jessica D and Kardia, Sharon and Bouchard, Claude and Raffel, Leslie and Uitterlinden, A.G and Franco, Oscar and Vasan, Ramachanan and O'Donnell, Christopher and Taylor, Kent and Liu, K.Y and Bottinger, Erwin and Gottesman, Rebecca and Daw, E. Warwick and Giulianini, Franco and Ganesh, Santhi and Salfati, Elias and Harris, Tamara and Launer, L.J and Dörr, Marcus and Felix, Stephan and Rettig, Rainer and Völzke, Henry and Kim, Eric and Lee, Wen-Jane and Lee, I.T and Sheu, W.H.-H and Tsosie, K.S and Edwards, D.R.V and Liu, Yongmei and Correa, A and Weir, David and Völker, Uwe and Ridker, Paul and Boerwinkle, Eric and Gudnason, Vilmundur and Reiner, Alexander and Van Duijn, C.M and Borecki, Ingrid and Edwards, Todd L and Chakravarti, Aravinda and Rotter, J.I and Psaty, Bruce and Loos, Ruth and Fornage, Myriam and Ehret, Georg and Newton-Cheh, Christopher and Levy, Daniel and Chasman, Daniel and Myocardial Infarction Genetics CAR and GOT2Dgenes Consortium and ExomeBP Consortium and CHD Exome Consortium and T2D-Genes Consortium and CKDGen Consortium and Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia and CHD Exome+ Consortium and GoT2DGenes Consortium and T2D-GENES Consortium
Nature Genetics, ISSN 1061-4036, 10/2016, Volume 48, Issue 10, pp. 1162 - 1170
textabstractMeta-analyses of association results for blood pressure using exome-centric single-variant and gene-based tests identified 31 new loci in a... 
INSULIN | MONOGENIC FORMS | DISEASE | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | RISK | MICE | EXPRESSION | GENOME-WIDE ASSOCIATION | LIPOPROTEIN-LIPASE GENE | REGION | Exome | Genetic Variation | Genome-Wide Association Study | Oligonucleotide Array Sequence Analysis | Blood Pressure - genetics | Humans | Genotype | Polymorphism, Single Nucleotide | Hypertension - genetics | Genome, Human | Studies | Proteins | Genealogy | Cardiovascular disease | Blood pressure | Genomes | Metabolism | Data bases | Meta-analysis
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2. Full Text Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
by Sims, Rebecca and Van Der Lee, Sven J and Naj, Adam C and Bellenguez, Céline and Badarinarayan, Nandini and Jakobsdottir, Johanna and Kunkle, Brian W and Boland, Anne and Raybould, Rachel and Bis, Joshua C and Martin, Eden R and Grenier-Boley, Benjamin and Heilmann-Heimbach, Stefanie and Chouraki, Vincent and Kuzma, Amanda B and Sleegers, Kristel and Vronskaya, Maria and Ruiz, Agustin and Graham, Robert R and Olaso, Robert and Hoffmann, Per and Grove, Megan L and Vardarajan, Badri N and Hiltunen, Mikko and Nöthen, Markus M and White, Charles C and Hamilton-Nelson, Kara L and Epelbaum, Jacques and Maier, Wolfgang and Choi, Seung-Hoan and Beecham, Gary W and Dulary, Cécile and Herms, Stefan and Smith, Albert V and Funk, Cory C and Derbois, Céline and Forstner, Andreas J and Ahmad, Shahzad and Li, Hongdong and Bacq, Delphine and Harold, Denise and Satizabal, Claudia L and Valladares, Otto and Squassina, Alessio and Thomas, Rhodri and Brody, Jennifer A and Qu, Liming and Sánchez-Juan, Pascual and Morgan, Taniesha and Wolters, Frank J and Zhao, Yi and Garcia, Florentino Sanchez and Denning, Nicola and Fornage, Myriam and Malamon, John and Naranjo, Maria Candida Deniz and Majounie, Elisa and Mosley, Thomas H and Dombroski, Beth and Wallon, David and Lupton, Michelle K and Dupuis, Josée and Whitehead, Patrice and Fratiglioni, Laura and Medway, Christopher and Jian, Xueqiu and Mukherjee, Shubhabrata and Keller, Lina and Brown, Kristelle and Lin, Honghuang and Cantwell, Laura B and Panza, Francesco and McGuinness, Bernadette and Moreno-Grau, Sonia and Burgess, Jeremy D and Solfrizzi, Vincenzo and Proitsi, Petra and Adams, Hieab H and Allen, Mariet and Seripa, Davide and Pastor, Pau and Cupples, L Adrienne and Price, Nathan D and Hannequin, Didier and Frank-García, Ana and Levy, Daniel and Chakrabarty, Paramita and Caffarra, Paolo and Giegling, Ina and Beiser, Alexa S and Giedraitis, Vilmantas and Hampel, Harald and Garcia, Melissa E and Wang, Xue and Lannfelt, Lars and Mecocci, Patrizia and Eiriksdottir, Gudny and Crane, Paul K and Pasquier, Florence and Boccardi, Virginia and ... and EADI and GERAD PERADES and ARUKConsortium and CHARGE and ADGC and GERAD/PERADES, CHARGE, ADGC, EADI and ARUK Consortium and Stockholms universitet and Centrum för forskning om äldre och åldrande (ARC), (tills m KI) and Samhällsvetenskapliga fakulteten
Nature Genetics, ISSN 1061-4036, 09/2017, Volume 49, Issue 9, pp. 1373 - 1384
We identified rare coding variants associated with Alzheimer's disease in a three-stage case-control study of 85,133 subjects. In stage 1, we genotyped 34,174... 
COMMON VARIANTS | IDENTIFIES VARIANTS | METAANALYSIS | GENOTYPE IMPUTATION | LOW-FREQUENCY | SUSCEPTIBILITY | GENETICS & HEREDITY | RISK | LOCI | WAVE2 COMPLEX | GENOME-WIDE ASSOCIATION | Amino Acid Sequence | Microglia - metabolism | Genetic Predisposition to Disease - genetics | Gene Frequency | Humans | Immunity, Innate - genetics | Genotype | Gene Expression Profiling | Case-Control Studies | Linkage Disequilibrium | Membrane Glycoproteins - genetics | Sequence Homology, Amino Acid | Exome - genetics | Protein Interaction Maps - genetics | Adaptor Proteins, Signal Transducing - genetics | Phospholipase C gamma - genetics | Polymorphism, Single Nucleotide | Alzheimer Disease - genetics | Odds Ratio | Receptors, Immunologic - genetics | Immune response | Genetic variation | Physiological aspects | Development and progression | Genetic aspects | Research | Alzheimer's disease | Neurodegenerative diseases | Genes | Genomics | Health risks | Innate immunity | Genomes | Disease control | Immunity | Microglia | Proteins | Studies | Consortia | DNA microarrays | Genotyping | Gene frequency | DNA methylation | Alzheimers disease | Protein interaction | Bioinformatics | Genotypes | Immune system | Biological Sciences | Naturvetenskap | Natural Sciences | Biologiska vetenskaper
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3. Full Text Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks
by Peloso, Gina M and Auer, Paul L and Bis, Joshua C and Voorman, Arend and Morrison, Alanna C and Stitziel, Nathan O and Brody, Jennifer A and Khetarpal, Sumeet A and Crosby, Jacy R and Fornage, Myriam and Isaacs, Aaron and Jakobsdottir, Johanna and Feitosa, Mary F and Davies, Gail and Huffman, Jennifer E and Manichaikul, Ani and Davis, Brian and Lohman, Kurt and Joon, Aron Y and Smith, Albert V and Grove, Megan L and Zanoni, Paolo and Redon, Valeska and Demissie, Serkalem and Lawson, Kim and Peters, Ulrike and Carlson, Christopher and Jackson, Rebecca D and Ryckman, Kelli K and Mackey, Rachel H and Robinson, Jennifer G and Siscovick, David S and Schreiner, Pamela J and Mychaleckyj, Josyf C and Pankow, James S and Hofman, Albert and Uitterlinden, Andre G and Harris, Tamara B and Taylor, Herman A and Taylor, Kent D and Stafford, Jeanette M and Reynolds, Lindsay M and Marioni, Riccardo E and Dehghan, Abbas and Franco, Oscar H and Patel, Aniruddh P and Lu, Yingchang and Hindy, George and Gottesman, Omri and Bottinger, Erwin P and Melander, Olle and Orho-Melander, Marju and Loos, Ruth J.F and Duga, Stefano and Merlini, Piera Angelica and Farrall, Martin and Goel, Anuj and Asselta, Rosanna and Girelli, Domenico and Martinelli, Nicola and Shah, Svati H and Kraus, William E and Li, Mingyao and Rader, Daniel J and Reilly, Muredach P and McPherson, Ruth and Watkins, Hugh and Ardissino, Diego and Zhang, Qunyuan and Wang, Judy and Tsai, Michael Y and Correa, Adolfo and Griswold, Michael E and Lange, Leslie A and Starr, John M and Rudan, Igor and Eiriksdottir, Gudny and Launer, Lenore J and Ordovas, Jose M and Levy, Daniel and Chen, Y.-D. Ida and Reiner, Alexander P and Hayward, Caroline and Polasek, Ozren and Deary, Ian J and Borecki, Ingrid B and Liu, Yongmei and Gudnason, Vilmundur and Wilson, James G and van Duijn, Cornelia M and Kooperberg, Charles and Rich, Stephen S and Psaty, Bruce M and Rotter, Jerome I and O’Donnell, Christopher J and Rice, Kenneth and Boerwinkle, Eric and Kathiresan, Sekar and Cupples, L. Adrienne and NHLBI GO Exome Sequencing Project and Diabetes - Cardiovascular Disease and Diabetes - kardiovaskulär sjukdom and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and Lund University and EpiHealth: Epidemiology for Health and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
The American Journal of Human Genetics, ISSN 0002-9297, 02/2014, Volume 94, Issue 2, pp. 223 - 232
Low-frequency coding DNA sequence variants in the proprotein convertase subtilisin/kexin type 9 gene ( ) lower plasma low-density lipoprotein cholesterol... 
DENSITY-LIPOPROTEIN CHOLESTEROL | FACTOR ACETYLHYDROLASES | PROTEIN | LDL | GENETICS & HEREDITY | PCSK9 | PLATELET-ACTIVATING-FACTOR | TRAITS | Genetic Code | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Middle Aged | Male | Genetic Variation | 1-Alkyl-2-acetylglycerophosphocholine Esterase - genetics | Adult | Cholesterol, LDL - blood | Female | Subtilisins - metabolism | African Continental Ancestry Group - genetics | Coronary Disease - blood | European Continental Ancestry Group - genetics | Genetic Association Studies | Gene Frequency | Mice, Inbred C57BL | Linear Models | Cholesterol, HDL - genetics | Sequence Analysis, DNA | 1-Alkyl-2-acetylglycerophosphocholine Esterase - metabolism | Cholesterol, LDL - genetics | Phenotype | Animals | Coronary Disease - genetics | Alleles | Triglycerides - blood | Cholesterol, HDL - blood | Subtilisins - genetics | Aged | Mice | Cohort Studies | Genetic code | Genetic variation | Physiological aspects | Genetic research | Genetic aspects | Research | Coronary heart disease | Population genetics | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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4. Full Text Exome-wide association study of plasma lipids in >300,000 individuals
by Liu, Dajiang J and Peloso, Gina M and Yu, Haojie and Butterworth, Adam S and Wang, Xiao and Mahajan, Anubha and Saleheen, Danish and Emdin, Connor and Alam, Dewan and Alves, Alexessander Couto and Amouyel, Philippe and Di Angelantonio, Emanuele and Arveiler, Dominique and Assimes, Themistocles L and Auer, Paul L and Baber, Usman and Ballantyne, Christie M and Bang, Lia E and Benn, Marianne and Bis, Joshua C and Boehnke, Michael and Boerwinkle, Eric and Bork-Jensen, Jette and Bottinger, Erwin P and Brandslund, Ivan and Brown, Morris and Busonero, Fabio and Caulfield, Mark J and Chambers, John C and Chasman, Daniel I and Chen, Y. Eugene and Chen, Yii-Der Ida and Chowdhury, Rajiv and Christensen, Cramer and Chu, Auey Y and Connell, John M and Cucca, Francesco and Cupples, L. Aienne and Damrauer, Scott M and Davies, Gail and Deary, Ian J and Dedoussis, George and Denny, Joshua C and Dominiczak, Anna and Dubé, Marie-Pierre and Ebeling, Tapani and Eiriksdottir, Gudny and Esko, Tõnu and Farmaki, Aliki-Eleni and Feitosa, Mary F and Ferrario, Marco and Ferrieres, Jean and Ford, Ian and Fornage, Myriam and Franks, Paul W and Frayling, Timothy M and Frikke-Schmidt, Ruth and Fritsche, Lars G and Frossard, Philippe and Fuster, Valentin and Ganesh, Santhi K and Gao, Wei and Garcia, Melissa E and Gieger, Christian and Giulianini, Franco and Goodarzi, Mark O and Grallert, Harald and Grarup, Niels and Groop, Leif and Grove, Megan L and Gudnason, Vilmundur and Hansen, Torben and Harris, Tamara B and Hayward, Caroline and Hirschhorn, Joel N and Holmen, Oddgeir L and Huffman, Jennifer and Huo, Yong and Hveem, Kristian and Jabeen, Sehrish and Jackson, Anne U and Jakobsdottir, Johanna and Jarvelin, Marjo-Riitta and Jensen, Gorm B and Jørgensen, Marit E and Jukema, J. Wouter and Justesen, Johanne M and Kamstrup, Pia R and Kanoni, Stavroula and Karpe, Freik and Kee, Frank and Khera, Amit V and Klarin, Derek and Koistinen, Heikki A and Kooner, Jaspal S and Kooperberg, Charles and Kuulasmaa, Kari and Kuusisto, Johanna and Laakso, Markku and Lakka, Timo and ... and VA Million Veteran Program and Charge Diabet Working Grp and EPIC-CVD Consortium and EPIC-InterAct Consortium and GOLD Consortium and Charge Diabetes Working Group and The EPIC-InterAct Consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Umeå universitet and Medicin
Nature genetics, ISSN 1061-4036, 2017, Volume 49, Issue 12, pp. 1758 - 1766
We screened variants on an exome-focused genotyping array in >300,000 participants (replication in >280,000 participants) and identified 444 independent... 
APOBEC-1 COMPLEMENTATION FACTOR | MYELOPROLIFERATIVE DISORDERS | LOW-FREQUENCY | CLONAL HEMATOPOIESIS | B MESSENGER-RNA | GENETICS & HEREDITY | TYROSINE KINASE JAK2 | CARDIOVASCULAR-DISEASE | MACULAR DEGENERATION | GENETIC ARCHITECTURE | CODING-SEQUENCE VARIANTS | Genetic Predisposition to Disease - genetics | Diabetes Mellitus, Type 2 - genetics | Humans | Risk Factors | Genetic Association Studies - methods | Genotype | Coronary Artery Disease - blood | Macular Degeneration - blood | Genetic Variation | Diabetes Mellitus, Type 2 - blood | Exome - genetics | Phenotype | Macular Degeneration - genetics | Lipids - blood | Coronary Artery Disease - genetics | Genome-wide association studies | Genetic aspects | Blood lipids | Identification and classification | Methods | Plasma | Lipoproteins (low density) | Liver | Lipids | Risk | Cardiovascular disease | Genomes | Macular degeneration | Consortia | Janus kinase 2 | Heart diseases | Lipoproteins (high density) | Age | Diabetes mellitus | Coronary artery | Health risks | Thalassemia | Triglycerides | Coronary artery disease | Loci | Cholesterol | Lipolysis | Studies | Lipoproteins | Genotyping | Alleles | Quality control | Diabetes | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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5. Full Text Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility
by Wessel, Jennifer and Chu, Auey Y and Willems, Sara and Wang, Shuai and Yaghootkar, Hanieh and Brody, Jennifer and Dauriz, Marco and Hivert, Marie-France and Raghavan, Sridharan and Lipovich, Leonard and Hidalgo, Bertha and Fox, Keolu and Huffman, Jennifer and An, Ping and Lu, Yingchang and Rasmussen-Torvik, Laura and Grarup, Niels and Ehm, Margaret G and Li, Li and Balidge, Abigail S and Stancáková, Alena and Abrol, Ravinder and Besse, Céline and Boland, Anne and Bork-Jensen, Jette and Fornage, Myriam and Freitag, Christine and Garcia, Melissa and Guo, Xiuqing and Hara, Kazuo and Isaacs, Aaron and Jakobsdottir, Margret and Lange, Leslie and Layton, Jill C and Li, Man and Zhao, Jing Hua and Meidtner, Karina and Morrison, Alanna and Nalls, Michael and Peters, Marjolein and Sabater-Lleal, Maria and Schurmann, Claudia and Silveira, Angela and Smith, G.D and Southam, Lorraine and Stoiber, Marcus H and Strawbridge, Rona and Taylor, Kent and Varga, Tibor V and Allin, Kristine H and Amin, Najaf and Aponte, Jennifer L and Aung, Tin and Barbieri, Caterina and Bihlmeyer, Nathan A and Boehnke, Michael and Bombieri, Cristina and Bowden, Donald and Burns, Sean M and Chen, Yuning and Chen, Yii-Deri and Cheng, Ching-Yu and Correa, D.D and Czajkowski, Jacek and Dehghan, Abbas and Ehret, Georg and Eiriksdottir, Gudny and Escher, Stefan A and Farmaki, Aliki-Eleni and Frånberg, Mattias and Gambaro, Giovanni and Giulianini, Franco and Goddard, William A and Goel, Anuj and Gottesman, Rebecca and Grove, Megan and Gustafsson, Stefan and Hai, Yang and Hallmans, Göran and Heo, Jiyoung and Hoffmann, Per and Ikram, Kamran and Jensen, Richard and Jørgensen, Marit and Jorgensen, Torben and Karaleftheri, Maria and Khor, C.C and Kirkpatrick, Anea and Kraja, Aldi and Kuusisto, Johanna and Lange, Ethan and Lee, I.T and Lee, Wen-Jane and Leong, Aaron and Liao, Jie and Liu, Chunyu and Liu, Yongmei and Lindgren, Cecilia and Linneberg, Allan and Malerba, Giovanni and ... and The EPIC-InterAct Consortium and EPIC-InterAct Consortium and Numerisk analys och datalogi (NADA) and Naturvetenskapliga fakulteten and Stockholms universitet and Science for Life Laboratory (SciLifeLab)
Nature Communications, ISSN 2041-1723, 01/2015, Volume 6, Issue 1, p. 5897
Fasting glucose and insulin are intermediate traits for type 2 diabetes. Here we explore the role of coding variation on these traits by analysis of variants... 
TRIGLYCERIDE LEVELS | GLUCAGON-LIKE PEPTIDE-1 | INSULIN-RESISTANCE | CODING VARIATION | MULTIDISCIPLINARY SCIENCES | GERMLINE MUTATIONS | GLYCEMIC TRAITS | PLASMA-GLUCOSE | RECEPTOR GENE | SEQUENCING DATA | GENOME-WIDE ASSOCIATION | Glucose-6-Phosphatase - genetics | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genetic Association Studies | Oligonucleotide Array Sequence Analysis | Diabetes Mellitus, Type 2 - genetics | Humans | Mutation Rate | Genetic Loci | Insulin - blood | Genetic Variation | Glucagon-Like Peptide-1 Receptor - genetics | Diabetes Mellitus, Type 2 - blood | Exome - genetics | Fasting - blood | Polymorphism, Single Nucleotide - genetics | African Continental Ancestry Group - genetics | Blood Glucose - metabolism | Biological Sciences | Medical Biotechnology | Naturvetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Biologiska vetenskaper | Medicinsk bioteknologi | Natural Sciences
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6. Full Text Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol
by Lange, Leslie A and Lange, Ethan M and Lange, Christoph and Hu, Youna and Zhang, Qunyuan and Zhang, Ji and Zhang, He and Xue, Chenyi and Schmidt, Ellen M and Tang, Hua and Tang, Zheng-Zheng and Bizon, Chris and Smith, Nicholas L and Smith, Joshua D and Smith, Albert V and Turner, Emily H and Jun, Goo and Kang, Hyun Min and Peloso, Gina and Auer, Paul L and Auer, Paul and Li, Kuo-ping and Li, Mingyao and Li, Yun and Li, Bingshan and Li, Dalin and Flannick, Jason and Fuchsberger, Christian and Gaulton, Kyle and Lindgren, Cecilia and Locke, Adam and Manning, Alisa and Sim, Xueling and Rivas, Manuel A and Holmen, Oddgeir L and Gottesman, Omri and Lu, Yingchang and Ruderfer, Douglas and Stahl, Eli A and Duan, Qing and Durda, Peter and Durda, J. Peter and Jiao, Shuo and Isaacs, Aaron and Hofman, Albert and Bis, Joshua C and Bis, Joshua and Correa, Adolfo and Griswold, Michael E and Jakobsdottir, Johanna and Schreiner, Pamela and Schreiner, Pamela J and Feitosa, Mary F and Huffman, Jennifer E and Crosby, Jacy and Wassel, Chrstina L and Wassel, Christina L and Do, Ron and Franceschini, Nora and Martin, Lisa and Martin, Lisa W and Martin, Thomas R and Robinson, Jennifer G and Assimes, Themistocles L and Crosslin, David R and Rosenthal, Elisabeth A and Tsai, Michael Y and Tsai, Michael and Rieder, Mark J and Farlow, Deborah N and Folsom, Aaron R and Lumley, Thomas and Fox, Ervin R and Fox, Caroline S and Fox, P. Keolu and Fox, Ervin and Carlson, Christopher S and Peters, Ulrike and Jackson, Rebecca D and Jackson, Rebecca and van Duijn, Cornelia M and Uitterlinden, André G and Levy, Daniel and Rotter, Jerome I and Taylor, Herman A and Taylor, Kira C and Taylor, Kent and Gudnason, Vilmundur and Siscovick, David S and Fornage, Myriam and Borecki, Ingrid B and Hayward, Caroline and Rudan, Igor and Chen, Wei-Min and Chen, Y. Eugene and Chen, Donna T and Chen, Ida Y and Bottinger, Erwin P and Loos, Ruth J.F and Sætrom, Pål and ... and NHLBI Grand Opportunity Exome Sequ and NHLBI Grand Opportunity Exome Sequencing Project and Genomik, diabetes och endokrinologi and Lund University and Genomics, Diabetes and Endocrinology and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
The American Journal of Human Genetics, ISSN 0002-9297, 02/2014, Volume 94, Issue 2, pp. 233 - 245
Elevated low-density lipoprotein cholesterol (LDL-C) is a treatable, heritable risk factor for cardiovascular disease. Genome-wide association studies (GWASs)... 
OBJECTIVES | HEART-DISEASE | PLASMA | GENE | SUSCEPTIBILITY | GENETICS & HEREDITY | DENSITY-LIPOPROTEIN-CHOLESTEROL | Dyslipidemias - genetics | Genetic Code | Follow-Up Studies | Humans | Middle Aged | Male | Proprotein Convertases - genetics | Exome | Dyslipidemias - blood | Serine Endopeptidases - genetics | Adult | Female | Receptors, LDL - genetics | Genome-Wide Association Study | Gene Frequency | Genotype | Sequence Analysis, DNA | Cholesterol, LDL - genetics | Phenotype | Apolipoproteins E - blood | Apolipoproteins E - genetics | Aged | Polymorphism, Single Nucleotide | Cohort Studies | Lipase - genetics | Proprotein Convertase 9 | Genetic code | Genetic variation | Physiological aspects | Genetic research | Cholesterol, LDL | Genetic aspects | Research | Nucleotide sequencing | DNA sequencing | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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