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Nature Medicine, ISSN 1078-8956, 01/2017, Volume 23, Issue 1, pp. 60 - 68
Forward genetic screens with CRISPR-Cas9 genome editing enable high-resolution detection of genetic vulnerabilities in cancer cells. We conducted genome-wide... 
MEDICINE, RESEARCH & EXPERIMENTAL | RNF43 | HUMAN-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | CANCER | CELL BIOLOGY | ESSENTIAL GENES | INHIBITION | GROWTH | MUTATIONAL LANDSCAPE | WNT | RECEPTORS | Frizzled Receptors - antagonists & inhibitors | Neoplasm Transplantation | Oncogene Proteins - genetics | Pancreatic Neoplasms - metabolism | Colorectal Neoplasms - genetics | Humans | Carcinoma, Pancreatic Ductal - metabolism | Molecular Targeted Therapy | RNA, Messenger - metabolism | Carcinoma, Pancreatic Ductal - genetics | Adenocarcinoma - metabolism | Flow Cytometry | Organoids - metabolism | Clustered Regularly Interspaced Short Palindromic Repeats | Adenocarcinoma - genetics | Real-Time Polymerase Chain Reaction | Colorectal Neoplasms - metabolism | Frizzled Receptors - metabolism | Pancreatic Neoplasms - genetics | DNA-Binding Proteins - genetics | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Antibodies - pharmacology | Animals | Wnt Signaling Pathway - drug effects | Wnt Signaling Pathway - genetics | Cell Cycle Checkpoints - drug effects | Fluorescent Antibody Technique | Organoids - drug effects | Cell Line, Tumor | Mice | Care and treatment | Pancreatic cancer | Innovations | Development and progression | Genotype | Genetic engineering | Cellular signal transduction | Genetic aspects | Health aspects | Proteins | Viral antibodies | Genomics | Colorectal cancer | Antibodies | Genomes | Genetic screening | Cell proliferation | Adenocarcinoma | CRISPR | Therapy | Immunoglobulins | Wnt protein | Frizzled protein | Xenotransplantation | Colorectal carcinoma | Cell surface | Signaling | Receptors | Organoids | Xenografts | Inhibition | Mutation | Pancreas | Cancer | Tumors | Recombinant
Journal Article
Cell, ISSN 0092-8674, 05/2015, Volume 161, Issue 4, pp. 933 - 945
Journal Article
The EMBO Journal, ISSN 0261-4189, 02/2019, Volume 38, Issue 4, p. n/a
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 2012, Volume 16, Issue 10, pp. 2379 - 2386
Undesired cell migration after targeted cell transplantation potentially limits beneficial effects for cardiac regeneration. Micro RNA s are known to be... 
cardiomyocyte progenitor cells | cell migration | RNA | micro | matrix metalloproteinases | Matrix metalloproteinases | MicroRNA | Cell migration | Cardiomyocyte progenitor cells | MYOCARDIUM | SURVIVAL | MEDICINE, RESEARCH & EXPERIMENTAL | STEM-CELLS | ISCHEMIC-HEART | PROLIFERATION | MICRORNA-155 | TRANSPLANTATION | DELIVERY | CELL BIOLOGY | INVASION | GROWTH | microRNA | Immunohistochemistry | RNA, Small Interfering - genetics | Cell Proliferation | Myocytes, Cardiac - cytology | Matrix Metalloproteinase 2 - metabolism | Humans | Matrix Metalloproteinase 16 - metabolism | Cells, Cultured | Gene Expression Regulation | MicroRNAs - metabolism | Stem Cells - metabolism | Blotting, Western | Gene Knockdown Techniques | Matrix Metalloproteinase 9 - metabolism | Transfection | Cloning, Molecular | MicroRNAs - genetics | Cell Movement | RNA, Small Interfering - metabolism | Analysis | Luciferase | Motility | Syngeneic grafts | Genes | Blocking antibodies | Antibodies | Transplantation | Assaying | Retention | Cell adhesion & migration | Efficiency | Conflicts of interest | Conditioning | Pulmonary arteries | Heart transplantation | Cloning | MiRNA | Cardiomyocytes | siRNA | Ribonucleic acid--RNA | Progenitor cells | Catheters | Regeneration | Mutagenesis | MicroRNAs | Stem cells | Cells (biology) | Binding sites | Apoptosis | Index Medicus | Original
Journal Article
Nature Medicine, ISSN 1078-8956, 11/2016
Forward genetic screens with CRISPR-Cas9 genome editing enable high-resolution detection of genetic vulnerabilities in cancer cells. We conducted genome-wide... 
Journal Article
Cell, ISSN 0092-8674, 05/2015, Volume 161, Issue 4, pp. 933 - 45
In Rspondin-based 3D cultures, Lgr5 stem cells from multiple organs form ever-expanding epithelial organoids that retain their tissue identity. We report the... 
Journal Article
Cell, ISSN 0092-8674, 2015, Volume 161, Issue 4, p. 933
In Rspondin-based 3D cultures, Lgr5 stem cells from multiple organs form ever-expanding epithelial organoids that retain their tissue identity. We report the... 
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 10/2012, Volume 16, Issue 10, pp. 2379 - 2386
Journal Article
Journal of Cellular and Molecular Medicine (Online), 10/2012, Volume 16, Issue 10, p. 2379
Undesired cell migration after targeted cell transplantation potentially limits beneficial effects for cardiac regeneration. MicroRNAs are known to be involved... 
Mutagenesis | Cloning | Cardiomyocytes | Ribonucleic acid--RNA | Cell adhesion & migration
Journal Article
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