X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
pharmacology & pharmacy (50) 50
index medicus (43) 43
humans (42) 42
models, biological (32) 32
pharmacokinetics (30) 30
computer simulation (20) 20
pharmacology/toxicology (16) 16
simulation (15) 15
metabolism (14) 14
models (14) 14
administration, oral (13) 13
biomedicine (13) 13
permeability (13) 13
pharmaceutical preparations - metabolism (13) 13
animals (12) 12
drug interactions (12) 12
pharmacy (11) 11
biochemistry, general (10) 10
pbpk (10) 10
p-glycoprotein (9) 9
prediction (9) 9
biotechnology (8) 8
in-vitro data (8) 8
male (8) 8
pharmaceutical preparations - administration & dosage (8) 8
adult (7) 7
analysis (7) 7
chemistry, pharmaceutical (7) 7
drug-drug interactions (7) 7
drugs (7) 7
female (7) 7
liver - metabolism (7) 7
pharmacology (7) 7
physiological aspects (7) 7
solubility (7) 7
tissue distribution (7) 7
young adult (7) 7
adme (6) 6
algorithms (6) 6
bioavailability (6) 6
chemistry, multidisciplinary (6) 6
cytochrome p-450 (6) 6
in vitro-in vivo extrapolation (6) 6
intestinal absorption (6) 6
administration, intravenous (5) 5
adolescent (5) 5
chemistry, medicinal (5) 5
clearance (5) 5
forecasting (5) 5
in-vitro (5) 5
interindividual variability (5) 5
kinetics (5) 5
mechanism-based inhibition (5) 5
metabolites (5) 5
middle aged (5) 5
pharmaceutical preparations - chemistry (5) 5
pharmacogenetics (5) 5
physiologically-based pharmacokinetics (5) 5
population (5) 5
research (5) 5
absorption (4) 4
biopharmaceutics (4) 4
cytochrome p-450 cyp3a - metabolism (4) 4
digoxin (4) 4
digoxin - pharmacokinetics (4) 4
dissolution (4) 4
drug design (4) 4
drug development (4) 4
gastrointestinal tract - metabolism (4) 4
health aspects (4) 4
infant (4) 4
infant, newborn (4) 4
internal medicine (4) 4
intestines - metabolism (4) 4
medicine & public health (4) 4
pharmaceutical science (4) 4
pharmacotherapy (4) 4
physiologically-based pharmacokinetic models (4) 4
simcyp (4) 4
toxicology (4) 4
vivo (4) 4
age (3) 3
anti-arrhythmia agents - metabolism (3) 3
anti-arrhythmia agents - pharmacokinetics (3) 3
area under curve (3) 3
articles (3) 3
biochemistry & molecular biology (3) 3
biomedical engineering (3) 3
biopharmaceutics - methods (3) 3
biotransformation (3) 3
caco-2 cells (3) 3
child (3) 3
child, preschool (3) 3
children (3) 3
complications and side effects (3) 3
cytochrome p-450 cyp2d6 - metabolism (3) 3
cytochrome-p450 3a activity (3) 3
disposition (3) 3
dosage and administration (3) 3
dosage forms (3) 3
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Current Pharmacology Reports, ISSN 2198-641X, 6/2016, Volume 2, Issue 3, pp. 161 - 169
There is a renewed surge of interest in applications of physiologically-based pharmacokinetic (PBPK) models by the pharmaceutical industry and regulatory... 
Physiologically-based pharmacokinetics | In vitro in vivo extrapolation | Biomedicine | Precision medicine | Regulatory science | Modelling and simulation | Cancer Research | Molecular Medicine | Pharmacology/Toxicology | Systems pharmacology | Biomedicine general | Pharmacometrics (H Kimko, Section Editor)
Journal Article
Journal Article
Clinical Pharmacokinetics, ISSN 0312-5963, 02/2019, Volume 58, Issue 2, pp. 235 - 262
Background The growth of fetal organs is a dynamic process involving considerable changes in the anatomical and physiological parameters that can alter fetal... 
3-DIMENSIONAL ULTRASONOGRAPHY | NORMAL-PREGNANCY | HUMAN-FETUS | GESTATIONAL-AGE | INTESTINAL LENGTH | URINE PRODUCTION | PHARMACOLOGY & PHARMACY | BODY-COMPOSITION | WEIGHT ESTIMATION | HUMAN GASTROINTESTINAL-TRACT | LUNG-VOLUME | Index Medicus
Journal Article
Toxicology Letters, ISSN 0378-4274, 10/2017, Volume 280, pp. S290 - S290
Journal Article
Expert Review of Clinical Pharmacology, ISSN 1751-2433, 03/2011, Volume 4, Issue 2, pp. 261 - 274
Current guidance issued by the US FDA to assess the impact of renal impairment on the pharmacokinetics of a drug under development has recently been updated to... 
systems biology | pharmacokinetics | metabolism | modeling | in vitro-in vivo extrapolation | renal impairment | Enzymes | Medical research | Liver diseases | Gastrointestinal agents | Metabolites | Physiological aspects | Medicine, Experimental | Protein binding
Journal Article
Journal Article
Archives of Disease in Childhood, ISSN 0003-9888, 01/2016, Volume 101, Issue 1, pp. e1 - e1
There is little information on the development of biliary drug elimination (BE) with age. The aims of this study were to collate literature data on the... 
Digoxin | Analysis | Azithromycin | Ceftriaxone sodium | Dosage and administration | Ceftriaxone | Pharmacokinetics | Health aspects | Age
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 09/2013, Volume 102, Issue 9, pp. 3161 - 3173
Digoxin is the recommended substrate for assessment of P-glycoprotein (P-gp)-mediated drug–drug interactions (DDIs) . The overall aim of our study was to... 
P-glycoprotein | MDR1 | ABCB1 | simulation | transporter | pharmacokinetics | digoxin | transporter-mediated drug–drug interactions | P‐glycoprotein | transporter‐mediated drug–drug interactions | Digoxin | Simulation | Transporter-mediated drug-drug interactions | Pharmacokinetics | Transporter | CLEARANCE | CHEMISTRY, MEDICINAL | IN-VITRO DATA | PROTEIN-BINDING | CYP3A4 | CHEMISTRY, MULTIDISCIPLINARY | CYTOCHROME-P450 3A | TRANSPORT | IMPACT | METABOLISM | PHARMACOLOGY & PHARMACY | transporter-mediated drug-drug interactions | INHIBITORS | VERAPAMIL | Adjuvants, Anesthesia - pharmacology | Permeability - drug effects | Digoxin - metabolism | Enzyme Inhibitors - metabolism | Anti-Arrhythmia Agents - pharmacology | Humans | Enzyme Inhibitors - pharmacology | Verapamil - analogs & derivatives | Anti-Arrhythmia Agents - metabolism | Anti-Arrhythmia Agents - pharmacokinetics | Verapamil - pharmacology | Digoxin - pharmacology | Digoxin - pharmacokinetics | Drug Interactions | Models, Biological | Computer Simulation | ATP Binding Cassette Transporter, Sub-Family B - metabolism | Adjuvants, Anesthesia - metabolism | Midazolam - metabolism | Rifampin - pharmacology | Midazolam - pharmacology | Verapamil - metabolism | Rifampin - metabolism | Complications and side effects | Metabolites | Drug interactions | Models | Permeability | Pharmacists | Rifampin
Journal Article