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Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2016, Volume 113, Issue 13, pp. E1796 - E1805
Journal Article
Nature Medicine, ISSN 1078-8956, 10/2016, Volume 22, Issue 10, pp. 1108 - 1119
Continuous de novo fatty acid synthesis is a common feature of cancer that is required to meet the biosynthetic demands of a growing tumor. This process is... 
PROSTATE | SURVIVAL | MEDICINE, RESEARCH & EXPERIMENTAL | HOMEOSTASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA | PHOSPHORYLATION SITES | CELL BIOLOGY | SYNTHASE | METABOLISM | LIPOGENESIS | AMPK | HEPATIC STEATOSIS | Lung Neoplasms - drug therapy | Proto-Oncogene Proteins p21(ras) - genetics | Allosteric Regulation | Humans | Lung Neoplasms - metabolism | Molecular Targeted Therapy | Tumor Suppressor Protein p53 - genetics | Acetyltransferases - antagonists & inhibitors | Lipid Metabolism - genetics | Pyrimidinones - pharmacology | Acetyl-CoA Carboxylase - antagonists & inhibitors | Lung Neoplasms - genetics | Cell Proliferation - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Enzyme Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - genetics | Thiophenes - pharmacology | Mice, Knockout | Xenograft Model Antitumor Assays | Animals | Lipid Metabolism - drug effects | Cell Proliferation - drug effects | Mice | Carcinoma, Non-Small-Cell Lung - drug therapy | Fatty Acids - biosynthesis | Synthesis | Growth | Cancer cells | Genetic aspects | Models | Research | Lung cancer, Non-small cell | Fatty acids | Carboxylases | Animal models | p53 Protein | Xenotransplantation | Lung | Lung cancer | Pharmacology | LKB1 protein | Allosteric properties | Liability | Acetyl-CoA carboxylase | Xenografts | Carboplatin | Genetic engineering | Inhibition | Dimerization | Viability | Cancer | Tumors | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2013, Volume 110, Issue 2, pp. 453 - 458
Journal Article
Science, ISSN 0036-8075, 12/2010, Volume 330, Issue 6010, pp. 1543 - 1546
Journal Article
Journal Article