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Genome medicine, ISSN 1756-994X, 12/2018, Volume 10, Issue 1, pp. 96 - 15
Only a small fraction of patients respond to the drug prescribed to treat their disease, which means that most are at risk of unnecessary exposure to side... 
CIRCUITS | SINGLE-CELL | ENCYCLOPEDIA | VARIANTS | RNA-SEQ | TRANSCRIPTION | TIME | INFERENCE | IDENTIFICATION | EXPRESSION | GENETICS & HEREDITY | Drugs | Adverse and side effects | Genetic aspects | Research | Genetic regulation | Risk factors
Journal Article
Nature communications, ISSN 2041-1723, 2015, Volume 6, Issue 1, p. 5890
The main challenge for gaining biological insights from genetic associations is identifying which genes and pathways explain the associations. Here we present... 
NETWORK | INTEGRATION | MULTIDISCIPLINARY SCIENCES | CANDIDATE GENES | DISEASE | ARCHITECTURE | COMMON | LOCI | IDENTIFICATION | HEIGHT | DATA SETS | Genome-Wide Association Study - methods | Software | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
Nature Genetics, ISSN 1061-4036, 09/2015, Volume 47, Issue 9, pp. 979 - 986
Journal Article
Nature genetics, ISSN 1061-4036, 2014, Volume 46, Issue 11, pp. 1173 - 1186
Journal Article
Nature Genetics, ISSN 1061-4036, 10/2013, Volume 45, Issue 10, pp. 1238 - 1243
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 506, Issue 7488, pp. 376 - +
A major challenge in human genetics is to devise a systematic strategy to integrate disease-associated variants with diverse genomic and biological data sets... 
RECEPTOR INHIBITION | VARIANTS | MULTIDISCIPLINARY SCIENCES | DISEASE | SUSCEPTIBILITY | RISK | LOCI | IDENTIFICATION | TRAITS | GENOME-WIDE ASSOCIATION | RESOURCE | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Humans | Asian Continental Ancestry Group - genetics | Computational Biology | Male | Drug Repositioning | Molecular Targeted Therapy | Drug Discovery | Case-Control Studies | Arthritis, Rheumatoid - pathology | Mice, Knockout | Arthritis, Rheumatoid - metabolism | Arthritis, Rheumatoid - genetics | Animals | Arthritis, Rheumatoid - drug therapy | Alleles | Polymorphism, Single Nucleotide - genetics | Female | Hematologic Neoplasms - genetics | Mice | Hematologic Neoplasms - metabolism | Quantitative trait loci | Genome-wide association studies | Rheumatoid arthritis | Genetic research | Genetic aspects | Research | Human genetics | Disease | Hematology | Cytokines | Genes | Genomics | Genomes | Meta-analysis | Proteins | Confidence intervals | Hypotheses | Quality control | Epigenetics | Population | Genetics | Health risk assessment | Asians | Cancer | Index Medicus | Rheumatology and Autoimmunity | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Reumatologi och inflammation | Virtual screening | Klinisk medicin
Journal Article