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Science, ISSN 0036-8075, 1/2011, Volume 331, Issue 6016, pp. 435 - 439
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 10/2011, Volume 68, Issue 4, pp. 1057 - 1065
TrkB acts as an oncogenic kinase in a subset of human neuroblastomas. Lestaurtinib, a multi-kinase inhibitor with potent activity against Trk kinases, has... 
Lestaurtinib | Signal transduction | Medicine & Public Health | Targeted therapy | Receptor tyrosine kinase | Oncology | Cancer Research | Neuroblastoma | Pharmacology/Toxicology | SURVIVAL | CEP-751 KT-6587 | BDNF | FLT3 INHIBITOR | CHEMOTHERAPY | TRANSPLANTATION | GENE | ONCOLOGY | PHARMACOLOGY & PHARMACY | HIGH-RISK NEUROBLASTOMA | EXPRESSION | ANTITUMOR EFFICACY | Carbazoles - adverse effects | Humans | Carbazoles - administration & dosage | Child, Preschool | Treatment Outcome | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Protein Kinase Inhibitors - adverse effects | Dose-Response Relationship, Drug | Young Adult | Protein Kinase Inhibitors - administration & dosage | Maximum Tolerated Dose | Antineoplastic Agents - adverse effects | Neuroblastoma - drug therapy | Adolescent | Receptor, trkB - antagonists & inhibitors | Carbazoles - therapeutic use | Protein Kinase Inhibitors - pharmacology | Phosphorylation - drug effects | Child | Neuroblastoma - pathology | Tyrosine | Medical colleges | Care and treatment | Oncology, Experimental | Pancreatitis | Clinical trials | Research | Biometry | Consortia | Analysis | Product development | Phosphotransferases | Cancer | Drugs | Risk groups | Toxicity | TrkB receptors | Children | transaminase | Pharmacokinetics | BID protein | Index Medicus
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2017, Volume 35, Issue 15_suppl, pp. 10572 - 10572
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 03/2018, Volume 36, Issue 7_suppl, pp. 157 - 157
Journal Article
Pediatric Blood & Cancer, ISSN 1545-5009, 01/2016, Volume 63, Issue 1, pp. 21 - 26
Journal Article
Cancer Research, ISSN 0008-5472, 11/2002, Volume 62, Issue 22, pp. 6462 - 6466
Journal Article
Journal of Neuro-Oncology, ISSN 0167-594X, 2/2012, Volume 106, Issue 3, pp. 643 - 649
To estimate the sustained (≥8 weeks) objective response rate in pediatric patients with recurrent or progressive high-grade gliomas (HGG, Stratum A) or... 
Resistance | Neurology | Alkylating agent | Medicine & Public Health | Glioma | MGMT | Oncology | Pediatric | Brainstem glioma | AGT | PLUS O-6-BENZYLGUANINE | GLIOBLASTOMA-MULTIFORME | MGMT PROMOTER METHYLATION | MISMATCH REPAIR | CHILDRENS ONCOLOGY GROUP | CLINICAL NEUROLOGY | MALIGNANT GLIOMA | ANTITUMOR IMIDAZOTETRAZINES | ONCOLOGY | DRUG TEMOZOLOMIDE | NERVOUS-SYSTEM TUMORS | O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE | Tumor Suppressor Proteins - metabolism | Glioma - mortality | DNA Modification Methylases - metabolism | Dacarbazine - therapeutic use | Guanine - analogs & derivatives | Humans | Kaplan-Meier Estimate | Proportional Hazards Models | Child, Preschool | Ki-67 Antigen - metabolism | Male | Antineoplastic Agents - therapeutic use | Brain Stem Neoplasms - drug therapy | Young Adult | Brain Stem Neoplasms - mortality | Drug Therapy, Combination - methods | Adolescent | DNA Repair Enzymes - metabolism | Dacarbazine - analogs & derivatives | Female | Retrospective Studies | Child | Glioma - drug therapy | Guanine - therapeutic use | Antimitotic agents | Consortia | Pediatrics | Medical research | Brain | Gliomas | Brain tumors | Medicine, Experimental | Children | Antineoplastic agents | Health aspects | Index Medicus | temozolomide | Brain stem | Toxicity | Myelosuppression | glioma | brainstem glioma | resistance | pediatric | alkylating agent
Journal Article
Journal Article
Journal of Radiation Oncology, ISSN 1948-7894, 06/2017, Volume 6, Issue 2, pp. 153 - 160
Journal Article
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2016
Abstract Purpose/Objectives Clinically effective measurement of cognitive toxicity from photon radiotherapy (XRT) should be accurate, sensitive, and specific.... 
Radiology | Hematology, Oncology and Palliative Medicine
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2014, Volume 32, Issue 15_suppl, pp. 10077 - 10077
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2014, Volume 32, Issue 15_suppl, pp. 10076 - 10076
Journal Article