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International journal of cancer, ISSN 0020-7136, 2017, Volume 140, Issue 4, pp. 798 - 806
Journal Article
by George, Julie and Lim, Jing Shan and Jang, Se Jin and Cun, Yupeng and Ozretić, Luka and Kong, Gu and Leenders, Frauke and Lu, Xin and Fernández-Cuesta, Lynnette and Bosco, Graziella and Müller, Christian and Dahmen, Ilona and Jahchan, Nadine S and Park, Kwon-Sik and Yang, Dian and Karnezis, Anthony N and Vaka, Dedeepya and Torres, Angela and Wang, Maia Segura and Korbel, Jan O and Menon, Roopika and Chun, Sung-Min and Kim, Deokhoon and Wilkerson, Matt and Hayes, Neil and Engelmann, David and Pützer, Brigitte and Bos, Marc and Michels, Sebastian and Vlasic, Ignacija and Seidel, Danila and Pinther, Berit and Schaub, Philipp and Becker, Christian and Altmüller, Janine and Yokota, Jun and Kohno, Takashi and Iwakawa, Reika and Tsuta, Koji and Noguchi, Masayuki and Muley, Thomas and Hoffmann, Hans and Schnabel, Philipp A and Petersen, Iver and Chen, Yuan and Soltermann, Alex and Tischler, Verena and Choi, Chang-min and Kim, Yong-Hee and Massion, Pierre P and Zou, Yong and Jovanovic, Dragana and Kontic, Milica and Wright, Gavin M and Russell, Prudence A and Solomon, Benjamin and Koch, Ina and Lindner, Michael and Muscarella, Lucia A and la Torre, Annamaria and Field, John K and Jakopovic, Marko and Knezevic, Jelena and Castaños-Vélez, Esmeralda and Roz, Luca and Pastorino, Ugo and Brustugun, Odd-Terje and Lund-Iversen, Marius and Thunnissen, Erik and Köhler, Jens and Schuler, Martin and Botling, Johan and Sandelin, Martin and Sanchez-Cespedes, Montserrat and Salvesen, Helga B and Achter, Viktor and Lang, Ulrich and Bogus, Magdalena and Schneider, Peter M and Zander, Thomas and Ansén, Sascha and Hallek, Michael and Wolf, Jürgen and Vingron, Martin and Yatabe, Yasushi and Travis, William D and Nürnberg, Peter and Reinhardt, Christian and Perner, Sven and Heukamp, Lukas and Büttner, Reinhard and Haas, Stefan A and Brambilla, Elisabeth and Peifer, Martin and Sage, Julien and Thomas, Roman K
Nature (London), ISSN 1476-4687, 2015, Volume 524, Issue 7563, pp. 47 - 53
Journal Article
by Nik-Zainal, Serena and Davies, Helen and Staaf, Johan and Ramakrishna, Manasa and Glodzik, Dominik and Zou, Xueqing and Martincorena, Inigo and Alexandrov, Ludmil B and Martin, Sancha and Wedge, David C and Van Loo, Peter and Ju, Young Seok and Smid, Marcel and Brinkman, Arie B and Morganella, Sandro and Aure, Miriam R and Lingjærde, Ole Christian and Langerød, Anita and Ringnér, Markus and Ahn, Sung-Min and Boyault, Sandrine and Brock, Jane E and Broeks, Annegien and Butler, Adam and Desmedt, Christine and Dirix, Luc and Dronov, Serge and Fatima, Aquila and Foekens, John A and Gerstung, Moritz and Hooijer, Gerrit K. J and Jang, Se Jin and Jones, David R and Kim, Hyung-Yong and King, Tari A and Krishnamurthy, Savitri and Lee, Hee Jin and Lee, Jeong-Yeon and Li, Yilong and McLaren, Stuart and Menzies, Andrew and Mustonen, Ville and O’Meara, Sarah and Pauporté, Iris and Pivot, Xavier and Purdie, Colin A and Raine, Keiran and Ramakrishnan, Kamna and Rodríguez-González, F. Germán and Romieu, Gilles and Sieuwerts, Anieta M and Simpson, Peter T and Shepherd, Rebecca and Stebbings, Lucy and Stefansson, Olafur A and Teague, Jon and Tommasi, Stefania and Treilleux, Isabelle and Van den Eynden, Gert G and Vermeulen, Peter and Vincent-Salomon, Anne and Yates, Lucy and Caldas, Carlos and Veer, Laura van’t and Tutt, Andrew and Knappskog, Stian and Tan, Benita Kiat Tee and Jonkers, Jos and Borg, Åke and Ueno, Naoto T and Sotiriou, Christos and Viari, Alain and Futreal, P. Andrew and Campbell, Peter J and Span, Paul N and Van Laere, Steven and Lakhani, Sunil R and Eyfjord, Jorunn E and Thompson, Alastair M and Birney, Ewan and Stunnenberg, Hendrik G and van de Vijver, Marc J and Martens, John W. M and Børresen-Dale, Anne-Lise and Richardson, Andrea L and Kong, Gu and Thomas, Gilles and Stratton, Michael R and Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Nature (London), ISSN 1476-4687, 2016, Volume 534, Issue 7605, pp. 47 - 54
Journal Article
Trials, ISSN 1745-6215, 2016, Volume 17, Issue 1, p. 302
Journal Article
Journal Article
Clinical cancer research, ISSN 1557-3265, 2017, Volume 23, Issue 23, pp. 7340 - 7350
Purpose: Dysregulated expression of PLD1 has emerged as a hallmark feature of colorectal cancer, which remains a major cause of mortality worldwide. Aberrant... 
COLON-CANCER | STEM-CELLS | METASTASIS | ONCOLOGY | PATHWAY | TRANSCRIPTION | DISEASE | RESISTANCE | BETA-CATENIN | EXPRESSION | Up-Regulation | Colorectal Neoplasms - genetics | Humans | Gene Expression Regulation, Neoplastic | Transplantation, Heterologous | Intracellular Signaling Peptides and Proteins - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Proto-Oncogene Proteins c-akt - genetics | Phospholipase D - genetics | Proto-Oncogene Proteins c-akt - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Colorectal Neoplasms - metabolism | Cells, Cultured | Signal Transduction - genetics | Phospholipase D - metabolism | beta Catenin - metabolism | beta Catenin - genetics | Mice, Knockout | Phosphatidylinositol 3-Kinases - genetics | Animals | Wnt Signaling Pathway - genetics | Survival Analysis | Cell Line, Tumor | Mutation | Colorectal Neoplasms - pathology | Transcription factors | Wnt protein | Crosstalk | Colorectal carcinoma | Phospholipase D1 | Colorectal cancer | AKT protein | Lymphocytes T | Kinases | β-catenin | Signal transduction | Pathways | Xenografts | Survival value | Inhibition | Cell survival | Patients | Survival | 1-Phosphatidylinositol 3-kinase | Adenomatous polyposis coli | Phospholipase | Signaling | Inhibitors | Experimental design | Biomarkers | Aberration | Cancer
Journal Article
Scientific reports, ISSN 2045-2322, 2019, Volume 9, Issue 1, pp. 5873 - 9
... expression is frequently identified in hemangioblastoma of the central nervous system tae Hoon Roh1, Hyunee Yim2, Jin Roh2, Kyi Beom Lee2, so Hyun park2, seon-Yong... 
GERMLINE | DEFECTS | PHEOCHROMOCYTOMA | MULTIDISCIPLINARY SCIENCES | HIPPEL-LINDAU-DISEASE | PARAGANGLIOMAS | COMPLEX-II GENE | SDH MUTATIONS | HYPOXIA | GASTROINTESTINAL STROMAL TUMORS | ASSOCIATION | Immunohistochemistry | Tricarboxylic acid cycle | Electron transport chain | Succinate dehydrogenase | Mitochondria | Dehydrogenases | Central nervous system | Nervous system | Tumorigenesis | Tumors
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 11/2016, Volume 20, Issue 11, pp. 2160 - 2172
Reactive oxygen species (ROS) generation during purine metabolism is associated with xanthine oxidase and uric acid. However, the direct effect of hypoxanthine... 
atherosclerosis | cholesterol | APOE | hypoxanthine | ROS | MEDICINE, RESEARCH & EXPERIMENTAL | MACROPHAGES | RISK | REPERFUSION | MECHANISMS | SERUM URIC-ACID | CELL BIOLOGY | HEART | PLASMA-CONCENTRATIONS | DISEASE | PURINE METABOLISM | XANTHINE | Apolipoproteins E - deficiency | Cholesterol - blood | Humans | Male | Apolipoproteins E - metabolism | Hypercholesterolemia - pathology | Lipogenesis - genetics | Plaque, Atherosclerotic - blood | Plaque, Atherosclerotic - pathology | Hydrogen Peroxide - toxicity | Atherosclerosis - pathology | Hypoxanthine - pharmacology | Plaque, Atherosclerotic - metabolism | Mice, Inbred C57BL | Cholesterol - metabolism | Down-Regulation - drug effects | Down-Regulation - genetics | Hep G2 Cells | Mice, Knockout | Atherosclerosis - blood | Up-Regulation - drug effects | Animals | Models, Biological | Lipogenesis - drug effects | Acetylcysteine - pharmacology | Allopurinol - pharmacology | Oxidases | Antioxidants | Cysteine | Molybdenum compounds | RNA | Atherosclerosis | Physiological aspects | Uric acid | Apolipoproteins | Cystine | Rodents | Cholesterol | Oxidative stress | Hydrogen peroxide | Hemodialysis | Liver | Lipids | mRNA | Accumulation | Alcohol use | ABCA1 protein | Synthesis | Apolipoprotein E | Enzymes | Drinking behavior | Allopurinol | siRNA | Xanthine | Metabolism | Gene expression | Diet | Arteriosclerosis | Coronary vessels | Xanthine oxidase | Hypoxanthine | ATP-binding protein | Mice | Laboratory animals | Transporter | Smoking | Original
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2011, Volume 6, Issue 9, p. e24574
Journal Article