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Oncotarget, ISSN 1949-2553, 05/2018, Volume 9, Issue 39, pp. 25647 - 25660
Epigenomic alterations have been associated with both pathogenesis and progression of cancer. Here, we analyzed the epigenome of two high-risk APL (hrAPL)... 
Epi-drugs | PML-RARA | High-risk APL | Acute promyelocytic leukemia (APL) | Epigenome | Life Sciences | Cancer
Journal Article
Oncotarget, ISSN 1949-2553, 05/2018, Volume 9, Issue 39, pp. 25630 - 25646
Epigenetic alterations have been associated with both pathogenesis and progression of cancer. By screening of library compounds, we identified a novel hybrid... 
Epigenetics | Acetylation | Methylation | Apoptosis | Cancer | Life Sciences
Journal Article
Journal Article
Science, ISSN 0036-8075, 2014, Volume 345, Issue 6204, pp. 1251086 - 1578
Journal Article
Cell, ISSN 0092-8674, 11/2016, Volume 167, Issue 5, p. 1354
Innate immune memory is the phenomenon whereby innate immune cells such as monocytes or macrophages undergo functional reprogramming after exposure to... 
Epigenetic inheritance | Developmental biology | Communicable diseases | Genetic transcription | Molecular biology | Macrophages | Mitogens
Journal Article
Journal Article
Science, ISSN 0036-8075, 09/2014, Volume 345, Issue 6204, pp. 1578 - +
Monocyte differentiation into macrophages represents a cornerstone process for host defense. Concomitantly, immunological imprinting of either tolerance or... 
Journal Article
Cell reports, ISSN 2211-1247, 11/2016, Volume 17, Issue 8, pp. 2087 - 2100
The t(8;21) acute myeloid leukemia (AML)-associated oncoprotein AML1-ETO disrupts normal hematopoietic differentiation. Here, we have investigated its effects... 
Journal Article
Cell, ISSN 0092-8674, 11/2016, Volume 167, Issue 5, pp. 1369 - 1384.e19
Journal Article
The EMBO Journal, ISSN 0261-4189, 2009, Volume 28, Issue 10, pp. 1418 - 1428
We used ChIP‐Seq to map ERα‐binding sites and to profile changes in RNA polymerase II (RNAPII) occupancy in MCF‐7 cells in response to estradiol (E2),... 
SERMs | estrogen receptor α | RNA polymerase II | ChIP‐Seq | Estrogen receptor a | ChIP-Seq | TAMOXIFEN | BIOCHEMISTRY & MOLECULAR BIOLOGY | estrogen receptor alpha | PROLIFERATION | CELL BIOLOGY | BREAST-CANCER CELLS | HUMAN GENOME | PROMOTERS | ESTROGEN-RECEPTOR-ALPHA | MCF-7 CELLS | BINDING-SITES | TRANSCRIPTIONAL REGULATION | EXPRESSION
Journal Article
by Astle, William J and Elding, Heather and Jiang, Tao and Allen, Dave and Ruklisa, Dace and Mann, Alice L and Mead, Daniel and Bouman, Heleen and Riveros-Mckay, Fernando and Kostadima, Myrto A and Lambourne, John J and Sivapalaratnam, Suthesh and Downes, Kate and Kundu, Kousik and Bomba, Lorenzo and Berentsen, Kim and Bradley, John R and Daugherty, Louise C and Delaneau, Olivier and Freson, Kathleen and Garner, Stephen F and Grassi, Luigi and Guerrero, Jose and Haimel, Matthias and Janssen-Megens, Eva M and Kaan, Anita and Kamat, Mihir and Kim, Bowon and Mandoli, Amit and Marchini, Jonathan and Martens, Joost H.A and Meacham, Stuart and Megy, Karyn and O’Connell, Jared and Petersen, Romina and Sharifi, Nilofar and Sheard, Simon M and Staley, James R and Tuna, Salih and van der Ent, Martijn and Walter, Klaudia and Wang, Shuang-Yin and Wheeler, Eleanor and Wilder, Steven P and Iotchkova, Valentina and Moore, Carmel and Sambrook, Jennifer and Stunnenberg, Hendrik G and Di Angelantonio, Emanuele and Kaptoge, Stephen and Kuijpers, Taco W and Carrillo-de-Santa-Pau, Enrique and Juan, David and Rico, Daniel and Valencia, Alfonso and Chen, Lu and Ge, Bing and Vasquez, Louella and Kwan, Tony and Garrido-Martín, Diego and Watt, Stephen and Yang, Ying and Guigo, Roderic and Beck, Stephan and Paul, Dirk S and Pastinen, Tomi and Bujold, David and Bourque, Guillaume and Frontini, Mattia and Danesh, John and Roberts, David J and Ouwehand, Willem H and Butterworth, Adam S and Soranzo, Nicole
Cell, ISSN 0092-8674, 11/2016, Volume 167, Issue 5, pp. 1415 - 1429.e19
Journal Article