Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2007, Volume 104, Issue 7, pp. 2465 - 2470
There is considerable evidence from animal studies that the mesolimbic and mesocortical dopamine systems are sensitive to circulating gonadal steroid hormones....
Sex hormones | Luteal phase | Menstrual cycle | Amygdala | Magnetic resonance imaging | Sex linked differences | Estrogens | Men | Prefrontal cortex | Follicular phase | OVARIAN HORMONES INFLUENCE | DOPAMINE RELEASE | RHESUS-MONKEYS | BASOLATERAL AMYGDALA | COCAINE-SEEKING | MULTIDISCIPLINARY SCIENCES | CENTRAL-NERVOUS-SYSTEM | ORBITOFRONTAL CORTEX | GENDER-DIFFERENCES | PREFRONTAL CORTEX | ESTROUS-CYCLE | Magnetic Resonance Imaging | Brain - cytology | Humans | Neurons - physiology | Sex Factors | Adult | Female | Progesterone - blood | Reward | Brain - physiology | Estrogens - blood | Menstrual Cycle - physiology | Usage | Research | Steroid hormones | Neuroscience | Cognitive science | Biological Sciences
Sex hormones | Luteal phase | Menstrual cycle | Amygdala | Magnetic resonance imaging | Sex linked differences | Estrogens | Men | Prefrontal cortex | Follicular phase | OVARIAN HORMONES INFLUENCE | DOPAMINE RELEASE | RHESUS-MONKEYS | BASOLATERAL AMYGDALA | COCAINE-SEEKING | MULTIDISCIPLINARY SCIENCES | CENTRAL-NERVOUS-SYSTEM | ORBITOFRONTAL CORTEX | GENDER-DIFFERENCES | PREFRONTAL CORTEX | ESTROUS-CYCLE | Magnetic Resonance Imaging | Brain - cytology | Humans | Neurons - physiology | Sex Factors | Adult | Female | Progesterone - blood | Reward | Brain - physiology | Estrogens - blood | Menstrual Cycle - physiology | Usage | Research | Steroid hormones | Neuroscience | Cognitive science | Biological Sciences
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 10/2010, Volume 30, Issue 43, pp. 14305 - 14317
Perceptual decisions are made when sensory evidence accumulated over time reaches a decision threshold. Because decisions are also guided by prior information,...
TASK | ANTERIOR CINGULATE CORTEX | REACTION-TIME | BASAL GANGLIA | PARIETAL | INFORMATION-THEORY | UNCERTAINTY | MODEL | INFERENCE | NEUROSCIENCES | PREFRONTAL CORTEX | Mental Processes - physiology | Predictive Value of Tests | Humans | Perception - physiology | Linear Models | Male | Reaction Time - physiology | Psychophysics | Brain - physiology | Neural Pathways - physiology | Psychomotor Performance - physiology | Young Adult | Magnetic Resonance Imaging | Algorithms | Image Processing, Computer-Assisted | Bayes Theorem | Adult | Female | Decision Making - physiology | Neuroscience | Cognitive science
TASK | ANTERIOR CINGULATE CORTEX | REACTION-TIME | BASAL GANGLIA | PARIETAL | INFORMATION-THEORY | UNCERTAINTY | MODEL | INFERENCE | NEUROSCIENCES | PREFRONTAL CORTEX | Mental Processes - physiology | Predictive Value of Tests | Humans | Perception - physiology | Linear Models | Male | Reaction Time - physiology | Psychophysics | Brain - physiology | Neural Pathways - physiology | Psychomotor Performance - physiology | Young Adult | Magnetic Resonance Imaging | Algorithms | Image Processing, Computer-Assisted | Bayes Theorem | Adult | Female | Decision Making - physiology | Neuroscience | Cognitive science
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2009, Volume 106, Issue 2, pp. 617 - 622
In humans, dopamine neurotransmission is influenced by functional polymorphisms in the dopamine transporter (DA71) and catechol-Omethyltransferase (COMT)...
Drug carriers | Basal ganglia | Magnetic resonance imaging | Genetic variation | Alleles | Minisatellite repeats | Medical genetics | Midbrain | Prefrontal cortex | Genotypes | fMRI | COMT | DAT | HUMAN BRAIN | MESSENGER-RNA EXPRESSION | MULTIDISCIPLINARY SCIENCES | genetic variation | POLYMORPHISM | BIPOLAR DISORDER | PREFRONTAL CORTEX | OBSESSIVE-COMPULSIVE DISORDER | TRANSPORTER AVAILABILITY | CATECHOL-O-METHYLTRANSFERASE | COMT VAL(108/158) MET | VALMET GENOTYPE | Synaptic Transmission - physiology | Mesencephalon | Synaptic Transmission - genetics | Humans | Catechol O-Methyltransferase - physiology | Genotype | Mutation, Missense | Catechol O-Methyltransferase - genetics | Dopamine Plasma Membrane Transport Proteins - genetics | Oxygen - blood | Minisatellite Repeats | Polymorphism, Genetic | Prefrontal Cortex | Magnetic Resonance Imaging | Dopamine - physiology | Brain Mapping | Basal Ganglia | Reward | Dopamine Plasma Membrane Transport Proteins - physiology | Physiological aspects | Genetic aspects | Brain stimulation rewards | Dopamine receptors | Neuroscience | Cognitive science | Biological Sciences
Drug carriers | Basal ganglia | Magnetic resonance imaging | Genetic variation | Alleles | Minisatellite repeats | Medical genetics | Midbrain | Prefrontal cortex | Genotypes | fMRI | COMT | DAT | HUMAN BRAIN | MESSENGER-RNA EXPRESSION | MULTIDISCIPLINARY SCIENCES | genetic variation | POLYMORPHISM | BIPOLAR DISORDER | PREFRONTAL CORTEX | OBSESSIVE-COMPULSIVE DISORDER | TRANSPORTER AVAILABILITY | CATECHOL-O-METHYLTRANSFERASE | COMT VAL(108/158) MET | VALMET GENOTYPE | Synaptic Transmission - physiology | Mesencephalon | Synaptic Transmission - genetics | Humans | Catechol O-Methyltransferase - physiology | Genotype | Mutation, Missense | Catechol O-Methyltransferase - genetics | Dopamine Plasma Membrane Transport Proteins - genetics | Oxygen - blood | Minisatellite Repeats | Polymorphism, Genetic | Prefrontal Cortex | Magnetic Resonance Imaging | Dopamine - physiology | Brain Mapping | Basal Ganglia | Reward | Dopamine Plasma Membrane Transport Proteins - physiology | Physiological aspects | Genetic aspects | Brain stimulation rewards | Dopamine receptors | Neuroscience | Cognitive science | Biological Sciences
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 10/2010, Volume 30, Issue 42, pp. 14080 - 14090
Decision making consists of choosing among available options on the basis of a valuation of their potential costs and benefits. Most theoretical models of...
HUMAN BRAIN | CONTRASTING ROLES | NEURAL REPRESENTATION | HUMAN REWARD SYSTEM | ANTERIOR CINGULATE | FRONTAL-CORTEX | IMPULSIVE CHOICE | SUBJECTIVE VALUE | TIME | ORBITOFRONTAL CORTEX | NEUROSCIENCES | Cues | Humans | Male | Reaction Time - physiology | Neostriatum - physiology | Young Adult | Magnetic Resonance Imaging | Algorithms | Adult | Cerebral Cortex - physiology | Decision Making - physiology | Models, Neurological | Reward | Energy Metabolism - physiology | Photic Stimulation | Erotica | Prefrontal Cortex - physiology | Neuroscience | Cognitive science
HUMAN BRAIN | CONTRASTING ROLES | NEURAL REPRESENTATION | HUMAN REWARD SYSTEM | ANTERIOR CINGULATE | FRONTAL-CORTEX | IMPULSIVE CHOICE | SUBJECTIVE VALUE | TIME | ORBITOFRONTAL CORTEX | NEUROSCIENCES | Cues | Humans | Male | Reaction Time - physiology | Neostriatum - physiology | Young Adult | Magnetic Resonance Imaging | Algorithms | Adult | Cerebral Cortex - physiology | Decision Making - physiology | Models, Neurological | Reward | Energy Metabolism - physiology | Photic Stimulation | Erotica | Prefrontal Cortex - physiology | Neuroscience | Cognitive science
Journal Article
Psychological Medicine, ISSN 0033-2917, 2013, Volume 43, Issue 5, pp. 1059 - 1068
BACKGROUND: Pathological gambling (PG) is an impulse control disorder characterized by excessive monetary risk seeking in the face of negative consequences. We...
prospect theory | decision making | risk seeking | gambling | probability weighting | probability discounting | Behavioral addiction | PSYCHIATRY | BEHAVIOR | IDENTIFICATION | PSYCHOLOGY, CLINICAL | PSYCHOLOGY | PROBABILISTIC REWARDS | CHOICE | DECISION-MAKING | ALCOHOL | GAMBLERS | SCALE | DELAY | PROSPECT-THEORY | Decision Making | Impulsive Behavior | Models, Theoretical | Severity of Illness Index | Uncertainty | Gambling - psychology | Humans | Probability | Male | Psychometrics | Risk | Case-Control Studies | Set (Psychology) | Economics, Behavioral | Gambling - economics | Adult | Psychological Theory | Gambling | Addictive behaviors | Neuroscience | Cognitive science
prospect theory | decision making | risk seeking | gambling | probability weighting | probability discounting | Behavioral addiction | PSYCHIATRY | BEHAVIOR | IDENTIFICATION | PSYCHOLOGY, CLINICAL | PSYCHOLOGY | PROBABILISTIC REWARDS | CHOICE | DECISION-MAKING | ALCOHOL | GAMBLERS | SCALE | DELAY | PROSPECT-THEORY | Decision Making | Impulsive Behavior | Models, Theoretical | Severity of Illness Index | Uncertainty | Gambling - psychology | Humans | Probability | Male | Psychometrics | Risk | Case-Control Studies | Set (Psychology) | Economics, Behavioral | Gambling - economics | Adult | Psychological Theory | Gambling | Addictive behaviors | Neuroscience | Cognitive science
Journal Article
Neuroscience and Biobehavioral Reviews, ISSN 0149-7634, 05/2013, Volume 37, Issue 4, pp. 681 - 696
â–º A meta-analysis compared the brain responses to monetary, erotic and food rewards. â–º All rewards recruit the vmPFC, striatum, amygdala, anterior insula and...
Experienced value | Neuroimaging | fMRI | Orbitofrontal cortex | Reward outcome | Food reward | Erotic reward | Ventral striatum | Monetary reward | Anterior insula | Reward processing | Meta-analysis | FMRI | PREDICTION ERRORS | HUMAN MALES | HUMAN ORBITOFRONTAL CORTEX | VISUAL SEXUAL STIMULI | NEUROSCIENCES | ANTERIOR INSULAR CORTEX | VENTROMEDIAL PREFRONTAL CORTEX | CONNECTIVITY-BASED PARCELLATION | EVENT-RELATED FMRI | BEHAVIORAL SCIENCES | BRAIN ACTIVATION | HUMAN AMYGDALA | Amygdala - anatomy & histology | Corpus Striatum - anatomy & histology | Brain - anatomy & histology | Hypothalamus - physiology | Humans | Brain - physiology | Visual Cortex - physiology | Animals | Thalamus - physiology | Corpus Striatum - physiology | Prefrontal Cortex - anatomy & histology | Cerebral Cortex - physiology | Reward | Cerebral Cortex - anatomy & histology | Amygdala - physiology | Prefrontal Cortex - physiology | Diagnostic imaging
Experienced value | Neuroimaging | fMRI | Orbitofrontal cortex | Reward outcome | Food reward | Erotic reward | Ventral striatum | Monetary reward | Anterior insula | Reward processing | Meta-analysis | FMRI | PREDICTION ERRORS | HUMAN MALES | HUMAN ORBITOFRONTAL CORTEX | VISUAL SEXUAL STIMULI | NEUROSCIENCES | ANTERIOR INSULAR CORTEX | VENTROMEDIAL PREFRONTAL CORTEX | CONNECTIVITY-BASED PARCELLATION | EVENT-RELATED FMRI | BEHAVIORAL SCIENCES | BRAIN ACTIVATION | HUMAN AMYGDALA | Amygdala - anatomy & histology | Corpus Striatum - anatomy & histology | Brain - anatomy & histology | Hypothalamus - physiology | Humans | Brain - physiology | Visual Cortex - physiology | Animals | Thalamus - physiology | Corpus Striatum - physiology | Prefrontal Cortex - anatomy & histology | Cerebral Cortex - physiology | Reward | Cerebral Cortex - anatomy & histology | Amygdala - physiology | Prefrontal Cortex - physiology | Diagnostic imaging
Journal Article
Cerebral Cortex, ISSN 1047-3211, 02/2013, Volume 23, Issue 2, pp. 477 - 487
Learning to predict rewarding and aversive outcomes is based on the comparison between predicted and actual outcomes (prediction error: PE). Recent...
fMRI | reinforcement learning model | classical conditioning | aversive conditioning | appetitive conditioning | DOPAMINE NEURONS ENCODE | AVERSIVE STIMULI | HUMAN ORBITOFRONTAL CORTEX | HUMAN BRAIN | LATERAL HABENULA | NEUROSCIENCES | NUCLEUS-ACCUMBENS | NEURAL RESPONSES | DECISION-MAKING | STOP-SIGNAL TASK | HUMAN AMYGDALA | Punishment | Learning - physiology | Magnetic Resonance Imaging | Humans | Brain Mapping | Female | Male | Reward | Brain - physiology | Conditioning, Classical - physiology | Neuroscience | Cognitive science
fMRI | reinforcement learning model | classical conditioning | aversive conditioning | appetitive conditioning | DOPAMINE NEURONS ENCODE | AVERSIVE STIMULI | HUMAN ORBITOFRONTAL CORTEX | HUMAN BRAIN | LATERAL HABENULA | NEUROSCIENCES | NUCLEUS-ACCUMBENS | NEURAL RESPONSES | DECISION-MAKING | STOP-SIGNAL TASK | HUMAN AMYGDALA | Punishment | Learning - physiology | Magnetic Resonance Imaging | Humans | Brain Mapping | Female | Male | Reward | Brain - physiology | Conditioning, Classical - physiology | Neuroscience | Cognitive science
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2008, Volume 105, Issue 39, pp. 15106 - 15111
The dopamine system, which plays a crucial role in reward processing, is particularly vulnerable to aging. Significant losses over a normal lifespan have been...
Brain | Basal ganglia | Magnetic resonance imaging | Neurons | Humans | Midbrain | Prefrontal cortex | Slot machines | Behavioral neuroscience | Positron emission tomography | Aging | Reinforcement | fMRI | Dopamine | PET | PREDICTION ERRORS | HUMAN BRAIN | OLDER-ADULTS | MULTIDISCIPLINARY SCIENCES | NUCLEUS-ACCUMBENS | HEMODYNAMIC-RESPONSE | INTRACRANIAL SELF-STIMULATION | PREFRONTAL FUNCTION | ANTICIPATION | aging | reinforcement | dopamine | WORKING-MEMORY | Age Factors | Mesencephalon - metabolism | Middle Aged | Dihydroxyphenylalanine - analogs & derivatives | Dopamine - biosynthesis | Male | Positron-Emission Tomography | Magnetic Resonance Imaging | Dihydroxyphenylalanine - metabolism | Aging - physiology | Adult | Female | Aged | Reward | Prefrontal Cortex - physiology | Aging - metabolism | Reward (Psychology) | Physiological aspects | Research | Mesencephalon | Properties | Dopaminergic mechanisms | Neuroscience | Cognitive science | Biological Sciences
Brain | Basal ganglia | Magnetic resonance imaging | Neurons | Humans | Midbrain | Prefrontal cortex | Slot machines | Behavioral neuroscience | Positron emission tomography | Aging | Reinforcement | fMRI | Dopamine | PET | PREDICTION ERRORS | HUMAN BRAIN | OLDER-ADULTS | MULTIDISCIPLINARY SCIENCES | NUCLEUS-ACCUMBENS | HEMODYNAMIC-RESPONSE | INTRACRANIAL SELF-STIMULATION | PREFRONTAL FUNCTION | ANTICIPATION | aging | reinforcement | dopamine | WORKING-MEMORY | Age Factors | Mesencephalon - metabolism | Middle Aged | Dihydroxyphenylalanine - analogs & derivatives | Dopamine - biosynthesis | Male | Positron-Emission Tomography | Magnetic Resonance Imaging | Dihydroxyphenylalanine - metabolism | Aging - physiology | Adult | Female | Aged | Reward | Prefrontal Cortex - physiology | Aging - metabolism | Reward (Psychology) | Physiological aspects | Research | Mesencephalon | Properties | Dopaminergic mechanisms | Neuroscience | Cognitive science | Biological Sciences
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2016, Volume 113, Issue 41, pp. 11633 - 11638
Although popular discussion of testosterone’s influence on males often centers on aggression and antisocial behavior, contemporary theorists have proposed that...
Social status | Testosterone | Generosity | Aggression | Human males | ANDROGEN RECEPTOR | AGGRESSIVE-BEHAVIOR | testosterone | CHALLENGE HYPOTHESIS | MULTIDISCIPLINARY SCIENCES | aggression | PRISON-INMATES | generosity | social status | SOCIAL-BEHAVIOR | PLASMA TESTOSTERONE | human males | ESTROGEN | ET-AL | ORBITOFRONTAL CORTEX | AMYGDALA | Neuroscience | Cognitive science | Biological Sciences | Social Sciences
Social status | Testosterone | Generosity | Aggression | Human males | ANDROGEN RECEPTOR | AGGRESSIVE-BEHAVIOR | testosterone | CHALLENGE HYPOTHESIS | MULTIDISCIPLINARY SCIENCES | aggression | PRISON-INMATES | generosity | social status | SOCIAL-BEHAVIOR | PLASMA TESTOSTERONE | human males | ESTROGEN | ET-AL | ORBITOFRONTAL CORTEX | AMYGDALA | Neuroscience | Cognitive science | Biological Sciences | Social Sciences
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2002, Volume 99, Issue 22, pp. 14595 - 14600
Psychological and neurobiological theories of cognitive control must account for flexible, seemless transitions among cognitive operations. When subjects...
Neuroimaging | Alertness | Error rates | Biological Sciences | Magnetic resonance imaging | Memory interference | Experimentation | Working memory | Prefrontal cortex | Behavioral neuroscience | Triplets | Task switching | Inhibition | Cingulate | Prefrontal | Executive processes | ATTENTION | ANTERIOR CINGULATE CORTEX | HUMAN BRAIN | RHESUS-MONKEY | MULTIDISCIPLINARY SCIENCES | inhibition | TASK-SET | INHIBITORY MECHANISMS | PREFRONTAL CORTEX | executive processes | prefrontal | EVENT-RELATED FMRI | task switching | cingulate | SWITCH | WORKING-MEMORY | Brain - diagnostic imaging | Humans | Male | Reaction Time | Brain - physiology | Radiography | Neurons - physiology | Cognition - physiology | Adult | Female | Prefrontal Cortex - physiology | Task Performance and Analysis | Prefrontal Cortex - diagnostic imaging | Control (Psychology) | Cognition | Research | Neuroscience | Cognitive science
Neuroimaging | Alertness | Error rates | Biological Sciences | Magnetic resonance imaging | Memory interference | Experimentation | Working memory | Prefrontal cortex | Behavioral neuroscience | Triplets | Task switching | Inhibition | Cingulate | Prefrontal | Executive processes | ATTENTION | ANTERIOR CINGULATE CORTEX | HUMAN BRAIN | RHESUS-MONKEY | MULTIDISCIPLINARY SCIENCES | inhibition | TASK-SET | INHIBITORY MECHANISMS | PREFRONTAL CORTEX | executive processes | prefrontal | EVENT-RELATED FMRI | task switching | cingulate | SWITCH | WORKING-MEMORY | Brain - diagnostic imaging | Humans | Male | Reaction Time | Brain - physiology | Radiography | Neurons - physiology | Cognition - physiology | Adult | Female | Prefrontal Cortex - physiology | Task Performance and Analysis | Prefrontal Cortex - diagnostic imaging | Control (Psychology) | Cognition | Research | Neuroscience | Cognitive science
Journal Article
Brain, ISSN 0006-8950, 2013, Volume 136, Issue 8, pp. 2527 - 2538
Pathological gambling is an addictive disorder characterized by a persistent and compulsive desire to engage in gambling activities. This maladaptive behaviour...
Pathological gambling | Striatum | Functional MRI | Reward | Addiction | reward | MONETARY REWARDS | HUMAN ORBITOFRONTAL CORTEX | COCAINE ADDICTION | DOPAMINE RELEASE | IMPULSE CONTROL DISORDERS | PROBLEM GAMBLERS | addiction | ALCOHOL-CONSUMPTION | ATTENTIONAL BIAS | NEUROSCIENCES | CLINICAL NEUROLOGY | functional MRI | NICOTINE DEPENDENCE | pathological gambling | striatum | DRUG-ADDICTION | Basal Ganglia - physiopathology | Gambling - psychology | Brain - physiopathology | Humans | Middle Aged | Male | Magnetic Resonance Imaging | Functional Neuroimaging | Image Processing, Computer-Assisted | Motivation | Adult | Gambling - physiopathology | Neural Pathways - physiopathology | Photic Stimulation | Neuroscience | Cognitive science
Pathological gambling | Striatum | Functional MRI | Reward | Addiction | reward | MONETARY REWARDS | HUMAN ORBITOFRONTAL CORTEX | COCAINE ADDICTION | DOPAMINE RELEASE | IMPULSE CONTROL DISORDERS | PROBLEM GAMBLERS | addiction | ALCOHOL-CONSUMPTION | ATTENTIONAL BIAS | NEUROSCIENCES | CLINICAL NEUROLOGY | functional MRI | NICOTINE DEPENDENCE | pathological gambling | striatum | DRUG-ADDICTION | Basal Ganglia - physiopathology | Gambling - psychology | Brain - physiopathology | Humans | Middle Aged | Male | Magnetic Resonance Imaging | Functional Neuroimaging | Image Processing, Computer-Assisted | Motivation | Adult | Gambling - physiopathology | Neural Pathways - physiopathology | Photic Stimulation | Neuroscience | Cognitive science
Journal Article
FRONTIERS IN BEHAVIORAL NEUROSCIENCE, ISSN 1662-5153, 07/2019, Volume 13, p. 142
Taking other people's interests into account is a fundamental ability allowing humans to maintain relationships. Yet, the mechanisms by which monetary...
vicarious reward | social cognition | PAYOFF | motivation | DECISION-MODEL | RESPONSE BIAS | NEUROSCIENCES | ACCURACY | drift diffusion models | decision making | SEQUENTIAL-SAMPLING MODELS | BEHAVIORAL SCIENCES | drift rate | Accuracy | Motivation | Decision making | Computer applications | Drift | Mathematical models | Boundaries | Neuroscience | Cognitive science
vicarious reward | social cognition | PAYOFF | motivation | DECISION-MODEL | RESPONSE BIAS | NEUROSCIENCES | ACCURACY | drift diffusion models | decision making | SEQUENTIAL-SAMPLING MODELS | BEHAVIORAL SCIENCES | drift rate | Accuracy | Motivation | Decision making | Computer applications | Drift | Mathematical models | Boundaries | Neuroscience | Cognitive science
Journal Article