Statistics in Medicine, ISSN 0277-6715, 04/2008, Volume 27, Issue 8, pp. 1282 - 1304
This paper develops a causal or manipulation model framework for mediation analysis based on the concept of potential outcome. Using this framework, we provide...
interaction | linear structural model | causal inference | surrogate endpoints | structural equation model | Causal inference | Linear structural model | Surrogate endpoints | Interaction | Structural equation model | MEDICINE, RESEARCH & EXPERIMENTAL | SURROGATE END-POINTS | RANDOMIZED-TRIALS | MEDICAL INFORMATICS | STATISTICS | MARKER | INSTRUMENTAL VARIABLES | BINARY OUTCOMES | STATISTICS & PROBABILITY | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | CLINICAL-TRIALS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | STRUCTURAL EQUATION MODELS | PROPORTION | Linear Models | Models, Statistical | Outcome Assessment (Health Care) | Causality | Humans | Endpoint Determination
interaction | linear structural model | causal inference | surrogate endpoints | structural equation model | Causal inference | Linear structural model | Surrogate endpoints | Interaction | Structural equation model | MEDICINE, RESEARCH & EXPERIMENTAL | SURROGATE END-POINTS | RANDOMIZED-TRIALS | MEDICAL INFORMATICS | STATISTICS | MARKER | INSTRUMENTAL VARIABLES | BINARY OUTCOMES | STATISTICS & PROBABILITY | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | CLINICAL-TRIALS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | STRUCTURAL EQUATION MODELS | PROPORTION | Linear Models | Models, Statistical | Outcome Assessment (Health Care) | Causality | Humans | Endpoint Determination
Journal Article
Clinical Journal of the American Society of Nephrology, ISSN 1555-9041, 10/2018, Volume 13, Issue 10, pp. 1550 - 1555
Background and objectivesMany patients with ESKD face barriers in completing the steps required to obtain a transplant. These eight sequential steps are...
kidney transplantation | transplantation | Death | Waiting Lists | Kidney Failure, Chronic | Living Donors | Referral and Consultation | Control Groups | renal dialysis | UNITED-STATES | BARRIERS | RENAL-TRANSPLANTATION | Kidney Failure | CARE | Chronic | INTERVENTIONS | DISPARITIES | DISEASE | UROLOGY & NEPHROLOGY | BLACKS | CANDIDATES | ACCESS | Original
kidney transplantation | transplantation | Death | Waiting Lists | Kidney Failure, Chronic | Living Donors | Referral and Consultation | Control Groups | renal dialysis | UNITED-STATES | BARRIERS | RENAL-TRANSPLANTATION | Kidney Failure | CARE | Chronic | INTERVENTIONS | DISPARITIES | DISEASE | UROLOGY & NEPHROLOGY | BLACKS | CANDIDATES | ACCESS | Original
Journal Article
Cell Reports, ISSN 2211-1247, 12/2018, Volume 25, Issue 10, pp. 2904 - 2918.e8
Pancreatic β cell physiology changes substantially throughout life, yet the mechanisms that drive these changes are poorly understood. Here, we performed...
SILAM MudPIT mass spectrometry | amplifying pathway | triggering pathway | TCA cycle | isotope tracing | β cell | insulin secretion | aging | β cell maturation | quantitative proteomics | GLUCOSE-REGULATED ANAPLEROSIS | STIMULATED INSULIN-SECRETION | RAT | MALIC ENZYME | CATAPLEROSIS | ALGORITHM | MATURATION | PROTEINS | EXPRESSION | MOUSE ISLETS | CELL BIOLOGY
SILAM MudPIT mass spectrometry | amplifying pathway | triggering pathway | TCA cycle | isotope tracing | β cell | insulin secretion | aging | β cell maturation | quantitative proteomics | GLUCOSE-REGULATED ANAPLEROSIS | STIMULATED INSULIN-SECRETION | RAT | MALIC ENZYME | CATAPLEROSIS | ALGORITHM | MATURATION | PROTEINS | EXPRESSION | MOUSE ISLETS | CELL BIOLOGY
Journal Article
Nature Genetics, ISSN 1061-4036, 06/2017, Volume 49, Issue 6, pp. 946 - 952
Atrial fibrillation affects more than 33 million people worldwide and increases the risk of stroke, heart failure, and death(1,2). Fourteen genetic loci have...
VISUALIZATION | GENETIC-VARIATION | METAANALYSIS | SNP | ANNOTATION | SUSCEPTIBILITY | RISK | BURDEN | GENOME-WIDE ASSOCIATION | TOOL | GENETICS & HEREDITY | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | African Americans - genetics | Genetic Loci | Atrial Fibrillation - genetics | Quantitative Trait Loci | Pharmaceutical research | Genetic variation | Atrial fibrillation | Genetic research | Genetic aspects | Forecasts and trends | Drug discovery | Identification and classification | Risk factors | Heart | Cardiac arrhythmia | Thoracic surgery | Target recognition | Laboratories | Syngeneic grafts | Genes | Genomics | Risk | Genomes | Remodeling | Epidemiology | Fibrillation | Electrocardiography | Genetics | Cardiology | Heart diseases | Public health | Heart failure | Stroke | Genealogy | Internal medicine | Mortality | Loci | Meta-analysis | Medicine | Studies | Hospitals | Death | Gene loci | population genetics | gene-expression | genome-wide association studies | Genetik | Biological Sciences | Naturvetenskap | Natural Sciences | Biologiska vetenskaper
VISUALIZATION | GENETIC-VARIATION | METAANALYSIS | SNP | ANNOTATION | SUSCEPTIBILITY | RISK | BURDEN | GENOME-WIDE ASSOCIATION | TOOL | GENETICS & HEREDITY | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | African Americans - genetics | Genetic Loci | Atrial Fibrillation - genetics | Quantitative Trait Loci | Pharmaceutical research | Genetic variation | Atrial fibrillation | Genetic research | Genetic aspects | Forecasts and trends | Drug discovery | Identification and classification | Risk factors | Heart | Cardiac arrhythmia | Thoracic surgery | Target recognition | Laboratories | Syngeneic grafts | Genes | Genomics | Risk | Genomes | Remodeling | Epidemiology | Fibrillation | Electrocardiography | Genetics | Cardiology | Heart diseases | Public health | Heart failure | Stroke | Genealogy | Internal medicine | Mortality | Loci | Meta-analysis | Medicine | Studies | Hospitals | Death | Gene loci | population genetics | gene-expression | genome-wide association studies | Genetik | Biological Sciences | Naturvetenskap | Natural Sciences | Biologiska vetenskaper
Journal Article
Physics Letters B, ISSN 0370-2693, 09/2012, Volume 716, Issue 1, pp. 30 - 61
Results are presented from searches for the standard model Higgs boson in proton–proton collisions at and 8 TeV in the Compact Muon Solenoid experiment at the...
CMS | Higgs | Physics | PARTON DISTRIBUTIONS | SEARCH | PHYSICS, NUCLEAR | COLLIDERS | STANDARD MODEL | ELECTROWEAK CORRECTIONS | BROKEN SYMMETRIES | ASTRONOMY & ASTROPHYSICS | QCD CORRECTIONS | PP COLLISIONS | SPECTRUM | MODEL HIGGS-BOSON | PHYSICS, PARTICLES & FIELDS | Analysis | Collisions (Nuclear physics) | Searching | Elementary particles | Decay | Higgs bosons | Standard deviation | Solenoids | Standards | Bosons | Physics - High Energy Physics - Experiment | High Energy Physics - Experiment | PHYSICS OF ELEMENTARY PARTICLES AND FIELDS
CMS | Higgs | Physics | PARTON DISTRIBUTIONS | SEARCH | PHYSICS, NUCLEAR | COLLIDERS | STANDARD MODEL | ELECTROWEAK CORRECTIONS | BROKEN SYMMETRIES | ASTRONOMY & ASTROPHYSICS | QCD CORRECTIONS | PP COLLISIONS | SPECTRUM | MODEL HIGGS-BOSON | PHYSICS, PARTICLES & FIELDS | Analysis | Collisions (Nuclear physics) | Searching | Elementary particles | Decay | Higgs bosons | Standard deviation | Solenoids | Standards | Bosons | Physics - High Energy Physics - Experiment | High Energy Physics - Experiment | PHYSICS OF ELEMENTARY PARTICLES AND FIELDS
Journal Article
Immunity, ISSN 1074-7613, 04/2018, Volume 48, Issue 4, pp. 812 - 830.e14
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across...
tumor immunology | immunotherapy | cancer genomics | integrative network analysis | immuno-oncology | tumor microenvironment | immune subtypes | immunomodulatory | Immunology | Infectious Diseases | Immunology and Allergy | GENOMIC ANALYSES | INFORMATION | T-CELL-RECEPTOR | REGULATORY NETWORK | CLASSIFICATION | IMMUNOLOGY | SEQUENCING DATA | SOMATIC MUTATIONS | COMPREHENSIVE ANALYSIS | PREDICTION | REVEALS | Transforming Growth Factor beta - immunology | Prognosis | Humans | Middle Aged | Th1-Th2 Balance - physiology | Male | Neoplasms - classification | Wound Healing - immunology | Young Adult | Transforming Growth Factor beta - genetics | Neoplasms - genetics | Neoplasms - immunology | Interferon-gamma - immunology | Adolescent | Aged, 80 and over | Adult | Female | Aged | Interferon-gamma - genetics | Wound Healing - genetics | Genomics - methods | Child | Macrophages - immunology | Cell proliferation | Cluster analysis | Transcription | Copy number | p53 Protein | Lung cancer | Genomics | Aneuploidy | Lymphocytes T | Genomes | Cell interactions | Macrophages | Immunotherapy | DNA methylation | Deoxyribonucleic acid--DNA | Immune system | Medical research | Wound healing | Immunomodulation | MiRNA | Stockholders | Inflammation | T cell receptors | Communications networks | Gene expression | White blood cells | Inventors | Medical prognosis | γ-Interferon | Mutation | Cancer | Tumors | Immune Subtypes | Integrative Network Analysis | Cancer Genomics | Immuno-oncology | Tumor immunology
tumor immunology | immunotherapy | cancer genomics | integrative network analysis | immuno-oncology | tumor microenvironment | immune subtypes | immunomodulatory | Immunology | Infectious Diseases | Immunology and Allergy | GENOMIC ANALYSES | INFORMATION | T-CELL-RECEPTOR | REGULATORY NETWORK | CLASSIFICATION | IMMUNOLOGY | SEQUENCING DATA | SOMATIC MUTATIONS | COMPREHENSIVE ANALYSIS | PREDICTION | REVEALS | Transforming Growth Factor beta - immunology | Prognosis | Humans | Middle Aged | Th1-Th2 Balance - physiology | Male | Neoplasms - classification | Wound Healing - immunology | Young Adult | Transforming Growth Factor beta - genetics | Neoplasms - genetics | Neoplasms - immunology | Interferon-gamma - immunology | Adolescent | Aged, 80 and over | Adult | Female | Aged | Interferon-gamma - genetics | Wound Healing - genetics | Genomics - methods | Child | Macrophages - immunology | Cell proliferation | Cluster analysis | Transcription | Copy number | p53 Protein | Lung cancer | Genomics | Aneuploidy | Lymphocytes T | Genomes | Cell interactions | Macrophages | Immunotherapy | DNA methylation | Deoxyribonucleic acid--DNA | Immune system | Medical research | Wound healing | Immunomodulation | MiRNA | Stockholders | Inflammation | T cell receptors | Communications networks | Gene expression | White blood cells | Inventors | Medical prognosis | γ-Interferon | Mutation | Cancer | Tumors | Immune Subtypes | Integrative Network Analysis | Cancer Genomics | Immuno-oncology | Tumor immunology
Journal Article