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Drug Metabolism and Disposition, ISSN 0090-9556, 07/2017, Volume 45, Issue 7, pp. 707 - 711
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 07/2017, Volume 45, Issue 7, p. 707
Medical conditions accompanying obesity often require drug therapy, but whether and how obesity alters the expression of drug-metabolizing enzymes and thus... 
Cytochrome | Enzymes | Obesity | Regulators | Cytochrome P450 | Liver | Transgenic mice | Pharmacology | CYP1A2 protein | Metabolism | Gene expression | Feeding | High fat diet | Diet | Rodents | Drug metabolism | Mice | Pharmacokinetics | CYP2D6 protein | Bile
Journal Article
Expert Opinion on Drug Metabolism & Toxicology, ISSN 1742-5255, 06/2010, Volume 6, Issue 6, pp. 689 - 699
Journal Article
Drug Metabolism Letters, ISSN 1872-3128, 03/2017, Volume 11, Issue 1, pp. 68 - 72
Background: Cytochrome P450 (CYP) 2D6 is a major drug-metabolizing enzyme, responsible for eliminating 25% of marketed drugs. We recently identified SHP as a... 
Fenofibrate | Drug interaction | SHP | PPARα | CYP2D6 | Cytochrome P450 | Cytochrome | Liver | Transgenic mice | mRNA | Gene expression | Proteins | Transfection | Hepatocytes | Protein folding | Rodents | Mice | CYP2D6 protein | Bile
Journal Article
JAMA psychiatry, ISSN 2168-622X, 9/2016, Volume 73, Issue 9, pp. 901 - 903
Journal Article
Clinical pharmacology and therapeutics, ISSN 0009-9236, 11/2018, Volume 104, Issue 5, pp. 974 - 982
CYP2D6 genetic polymorphisms are considered a major contributor to the large inter-individual variability in CYP2D6-mediated drug metabolism, but fail to... 
liver tissues | CYP2D6 | genetic polymorphisms | variability
Journal Article
Drug metabolism and disposition: the biological fate of chemicals, ISSN 0090-9556, 03/2019, Volume 47, Issue 3, pp. 194 - 202
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 2521 - 10
In Staphylococcus aureus, an important Gram-positive human pathogen, the SaeRS two-component system is essential for the virulence and a good target for the... 
GENE-EXPRESSION | MULTIDISCIPLINARY SCIENCES | INHIBITORS | Pathogens | Animal models | Streptozocin | Virulence | Gram-positive bacteria | Staphylococcus infections | Leukocytes (neutrophilic) | Drug development | Ribonucleic acid--RNA | Blood | Prophages | Deoxyribonucleic acid--DNA | Cancer
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 4621 - 4621
Abstract Although melphalan 200mg/m2 (Mel200) and autologous stem cell transplantation (ASCT) significantly prolong progression-free survival for multiple... 
Journal Article
Acta Pharmaceutica Sinica B, ISSN 2211-3835, 09/2016, Volume 6, Issue 5, pp. 504 - 509
UDP-glucuronosyltransferase 1A9 (UGT1A9) is a major phase II enzyme responsible for elimination of drugs and endogenous molecules. Clinical data have shown... 
17β-Estradiol | Drug metabolism | Estrogen receptor | UGT1A9 | Sex difference | Original
Journal Article
Journal Article
Journal of Clinical Monitoring and Computing, ISSN 1387-1307, 2018, Volume 33, Issue 4, pp. 657 - 663
In patients with obstructive sleep apnea, short-term use of a continuous positive airway pressure mask improves oxygenation, decreases the apnea-hypopnea... 
Propofol | STOP-Bang score | Continuous positive airway pressure | Obstructive sleep apnea | Apnea-hypopnea index | SCREEN | ANESTHESIOLOGY | HYPOPNEA | QUESTIONNAIRE | ASSOCIATION | Respiratory therapy | Oxygen | Stability | Saturation | Bladder | Risk | Sleep apnea | Oxygen content | Patients | Heart rate | Respiratory rate | Sleep | Anesthesia | Blood pressure | Oxygenation | Prostate
Journal Article
Drug Metabolism Letters, ISSN 1872-3128, 2012, Volume 6, Issue 2, pp. 116 - 119
Journal Article
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