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Nature, ISSN 0028-0836, 08/2018, Volume 560, Issue 7717, pp. 171 - 172
Better treatments are needed for the neglected tropical disease leishmaniasis. The development of a compound that tackles the disease in mice, and the... 
Microbiology | Medical research | MULTIDISCIPLINARY SCIENCES | Leishmaniasis | Humans | Leishmaniasis, Visceral | Cyclins | Drug Delivery Systems | Drug therapy | Vector-borne diseases | Parasites | Kinases | Parasitic diseases | Tropical diseases
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 08/2018, Volume 156, pp. 587 - 597
In the present work a series of aziridine-2,3-dicarboxylate inhibitors of papain-like cysteine proteases was designed, synthesized and tested. The compounds... 
Cruzain | Inhibitor | Cysteine protease | Leishmania | Aziridine | Rhodesain | CHEMISTRY, MEDICINAL | SPECIFICITIES | LIGAND EFFICIENCY | ACIDS | DOCKING | MEXICANA | CPB | MICHAEL TYPE ADDITION | FORCE-FIELD | AZIRIDINE-2,3-DICARBOXYLATES | Papain | Cysteine | Cystine
Journal Article
PLoS Neglected Tropical Diseases, ISSN 1935-2727, 06/2017, Volume 11, Issue 6, p. e0005626
Journal Article
Journal Article
Nature Reviews Microbiology, ISSN 1740-1526, 01/2013, Volume 11, Issue 1, pp. 58 - 66
Journal Article
by Klionsky, Daniel J and Abdalla, Fabio C and Abeliovich, Hagai and Abraham, Robert T and Acevedo-Arozena, Abraham and Adeli, Khosrow and Agholme, Lotta and Agnello, Maria and Agostinis, Patrizia and Aguirre-Ghiso, Julio A and Ahn, Hyung Jun and Ait-Mohamed, Ouardia and Ait-Si-Ali, Slimane and Akematsu, Takahiko and Akira, Shizuo and Al-Younes, Hesham M and Al-Zeer, Munir A and Albert, Matthew L and Albin, Roger L and Alegre-Abarrategui, Javier and Aleo, Maria Francesca and Alirezaei, Mehrdad and Almasan, Alexandru and Almonte-Becerril, Maylin and Amano, Atsuo and Amaravadi, Ravi K and Amarnath, Shoba and Amer, Amal O and Andrieu-Abadie, Nathalie and Anantharam, Vellareddy and Ann, David K and Anoopkumar-Dukie, Shailendra and Aoki, Hiroshi and Apostolova, Nadezda and Arancia, Giuseppe and Aris, John P and Asanuma, Katsuhiko and Asare, Nana Y.O and Ashida, Hisashi and Askanas, Valerie and Askew, David S and Auberger, Patrick and Baba, Misuzu and Backues, Steven K and Baehrecke, Eric H and Bahr, Ben A and Bai, Xue-Yuan and Bailly, Yannick and Baiocchi, Robert and Baldini, Giulia and Balduini, Walter and Ballabio, Andrea and Bamber, Bruce A and Bampton, Edward T.W and Juhász, Gábor and Bartholomew, Clinton R and Bassham, Diane C and Bast, Robert C and Batoko, Henri and Bay, Boon-Huat and Beau, Isabelle and Béchet, Daniel M and Begley, Thomas J and Behl, Christian and Behrends, Christian and Bekri, Soumeya and Bellaire, Bryan and Bendall, Linda J and Benetti, Luca and Berliocchi, Laura and Bernardi, Henri and Bernassola, Francesca and Besteiro, Sébastien and Bhatia-Kissova, Ingrid and Bi, Xiaoning and Biard-Piechaczyk, Martine and Blum, Janice S and Boise, Lawrence H and Bonaldo, Paolo and Boone, David L and Bornhauser, Beat C and Bortoluci, Karina R and Bossis, Ioannis and Bost, Frédéric and Bourquin, Jean-Pierre and Boya, Patricia and Boyer-Guittaut, Michaël and Bozhkov, Peter V and Brady, Nathan R and Brancolini, Claudio and Brech, Andreas and Brenman, Jay E and Brennand, Ana and Bresnick, Emery H and Brest, Patrick and Bridges, Dave and Bristol, Molly L and Brookes, Paul S and Brown, Eric J and Brumell, John H and ... and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Geriatrik and Institutionen för medicin och hälsa and Farmakologi and Experimentell patologi and Hälsouniversitetet and Cellbiologi
Autophagy, ISSN 1554-8627, 04/2012, Volume 8, Issue 4, pp. 445 - 544
Journal Article
PLoS Pathogens, ISSN 1553-7366, 01/2014, Volume 10, Issue 1
  The African trypanosome, Trypanosoma brucei, maintains an integral link between cell cycle regulation and differentiation during its intricate life cycle.... 
Proteins | Signal transduction | Genotype & phenotype | Phosphorylation | Plasmids | Cloning | Cell cycle | Cell division | Parasites | Kinases | Apoptosis | Defects
Journal Article