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Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 4378 - 4378
Abstract Background: Treatment-naive CLL patients displaying TP53 disruption (TP53 mutation and/or del(17p)) show heterogeneity in their clinical course. A few... 
Journal Article
International journal of laboratory hematology, ISSN 1751-5521, 10/2019, Volume 41, Issue 5, p. e109
Journal Article
International Journal of Laboratory Hematology, ISSN 1751-5521, 10/2019, Volume 41, Issue 5, pp. e109 - e112
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 3901 - 3901
Abstract Background: Deletions of 14q occur recurrently in mature B-cell neoplasms at a low frequency of 1.5% (Reindl et al., BJH 2010). In about one-third of... 
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 1707 - 1707
Abstract Background: CLL is characterized by a distinct pattern of cytogenetic abnormalities. The most frequent aberrations are deletions of 13q, 11q, 6q and... 
Journal Article
British Journal of Haematology, ISSN 0007-1048, 10/2018, Volume 183, Issue 1, pp. 47 - 59
Chronic Lymphocytic Leukaemia (CLL) is a heterogeneous disease with a clinical course dependent on cytogenetic features. However, in 15–20% of cases both... 
molecular genetics | cytogenetics | chronic lymphocytic leukaemia | RISK STRATIFICATION | RECURRENT MUTATIONS | TP53 MUTATIONS | SF3B1 MUTATIONS | INTERPHASE FISH | B-CELL LYMPHOCYTOSIS | CHRONIC LYMPHOCYTIC-LEUKEMIA | GENOMIC ABERRATIONS | IGVH MUTATION STATUS | HEMATOLOGY | DISEASE PROGRESSION | Risk Assessment - methods | Chromosome Banding | Prognosis | Humans | Middle Aged | In Situ Hybridization, Fluorescence | Male | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Phosphoproteins - genetics | RNA Splicing Factors - genetics | Comparative Genomic Hybridization | Chromosome Aberrations | Aged, 80 and over | Adult | Female | Immunoglobulin Variable Region - genetics | Aged | Polymorphism, Single Nucleotide | Mutation | Immunoglobulin Heavy Chains - genetics | Leukemia, Lymphocytic, Chronic, B-Cell - diagnosis | Molecular genetics | Gene mutations | Analysis | Leukemia | Genes | Genetic research | Cytogenetics | Single nucleotide polymorphisms | Tumor proteins | Blood cell count | Flow cytometry | Chronic lymphatic leukemia | Abnormalities | Variable region | Medical services | Fluorescence | Single-nucleotide polymorphism | Multivariate analysis | Parameter identification | Gene polymorphism | Patients | Subgroups | Gene sequencing | Impact analysis | White blood cells | Banding | CD38 antigen | Fluorescence in situ hybridization | Aberration | Arrays | Polymorphism
Journal Article
Blood, ISSN 0006-4971, 11/2013, Volume 122, Issue 21, pp. 1307 - 1307
Abstract Background MYC translocations are observed in a variety of mature B-cell neoplasms and are also found in ALL. A clear assignment to an entity is not... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 2803 - 2803
Abstract Background. The occurrence of clonal hematopoiesis increases with age and is associated with increased risk of hematologic malignancies (Jaiswal et... 
Journal Article
Cancer Genetics, ISSN 2210-7762, 2016, Volume 209, Issue 10, pp. 431 - 439
Journal Article
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 4379 - 4379
Abstract Background: CLL is characterized by a distinct pattern of translocations, genomic gains and losses and molecular mutations. The most frequent... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 3213 - 3213
Abstract Background: The clinical course in CLL is very heterogeneous ranging from stable disease to a rather rapid progression requiring treatment. The... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 1976 - 1976
Abstract Introduction: Precision medicine aims at the molecular profiling of patients to specifically target gene mutations. Targeted therapies now enter... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 3207 - 3207
Abstract Background: In chronic lymphocytic leukemia (CLL) one of the strongest prognostic factors is IGHV mutational status. Infrequently, patients present... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 3145 - 3145
Abstract Background: CALR is mutated in about 70% of patients with essential thrombocythemia and primary myelofibrosis lacking mutations in JAK2 and MPL. High... 
Journal Article
Leukemia, ISSN 0887-6924, 05/2018, Volume 32, Issue 5, pp. 1222 - 1228
Journal Article
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