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Journal Article
Circulation Research, ISSN 0009-7330, 12/2005, Volume 97, Issue 12, pp. 1314 - 1322
Journal Article
Annual Review of Physiology, ISSN 0066-4278, 01/2015, Volume 77, p. 505
  Channelopathies are a diverse set of disorders associated with defects in ion channel (and transporter) function. Although the vast majority of... 
Membranes | Protein synthesis | Protein folding | Ions | Biophysics
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, p. e87495
Spontaneous calcium waves in cardiac myocytes are caused by diastolic sarcoplasmic reticulum release (SR Ca2+ leak) through ryanodine receptors.... 
SYNTHASE | S-NITROSYLATION | HYPERTROPHY | CONTRACTION | PATHWAY | MULTIDISCIPLINARY SCIENCES | HEART-FAILURE | ENHANCEMENT | CA2+/CALMODULIN-DEPENDENT PROTEIN-KINASE | ARRHYTHMIA | CA2+ LEAK | Calcium - metabolism | Ryanodine Receptor Calcium Release Channel - metabolism | Nitric Oxide Synthase Type I - antagonists & inhibitors | Sarcoplasmic Reticulum - metabolism | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | NG-Nitroarginine Methyl Ester - pharmacology | Rabbits | Myocytes, Cardiac - cytology | Mice, Inbred C57BL | Cells, Cultured | Enzyme Inhibitors - pharmacology | Enzyme Activation - drug effects | Adrenergic Agents - pharmacology | Blotting, Western | Mice, Knockout | Nitric Oxide Synthase Type I - deficiency | Animals | Myocytes, Cardiac - drug effects | Isoproterenol - pharmacology | Myocytes, Cardiac - metabolism | Mice | Nitric Oxide Synthase Type I - genetics | Nitric Oxide - metabolism | Heart failure | Calcium-binding proteins | Nitric oxide | Heart | Reactive oxygen species | Phosphorylation | Calcium | Leak channels | Oxidizing agents | Fluorescence | Ryanodine receptors | Immunoblotting | AKT protein | Cardiovascular disease | Stimulation | Biology | Fluorescent indicators | Activation | Myocytes | Kinases | Isoproterenol | Data links | Proteins | Calcium signalling | Receptors | Sarcoplasmic reticulum | Rodents | Calcium-binding protein | Physiology | Oxidation | Heart diseases | Calmodulin | Cardiac muscle | Cardiomyocytes | Biophysics | Nitric-oxide synthase | Ostomy | Ventricle | NOS3 protein | Laboratory animals | Calcium (reticular) | Ca2+/calmodulin-dependent protein kinase II
Journal Article
Circulation Research, ISSN 0009-7330, 11/2014, Volume 115, Issue 11, pp. 929 - 938
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2010, Volume 49, Issue 1, pp. 25 - 32
Abstract Increased cardiac ryanodine receptor (RyR)-dependent diastolic SR Ca leak is present in heart failure and in conditions when adrenergic tone is high.... 
Cardiovascular | heart failure | SR Ca leak | CaMKII | ryanodine receptor | Arrhythmia | Heart failure | Ryanodine receptor | LEAK | CARDIAC & CARDIOVASCULAR SYSTEMS | RAT | SUDDEN-DEATH | PHOSPHORYLATION | CARDIAC RYANODINE RECEPTOR | SARCOPLASMIC-RETICULUM | RELEASE | FAILURE | PURKINJE-FIBERS | CELL BIOLOGY | THRESHOLD
Journal Article
Neurosurgery, ISSN 0148-396X, 10/2002, Volume 51, Issue 4, pp. 890 - 904
Journal Article