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BMC Bioinformatics, ISSN 1471-2105, 09/2013, Volume 14, Issue 11, pp. S1 - S1
Journal Article
Human Genetics, ISSN 0340-6717, 2/2014, Volume 133, Issue 2, pp. 125 - 138
Genome-wide association studies (GWAS) have rapidly become a powerful tool in genetic studies of complex diseases and traits. Traditionally, single... 
Human Genetics | Gene Function | Molecular Medicine | Biomedicine | Metabolic Diseases | DE-NOVO MUTATIONS | VARIANTS | GENETICS & HEREDITY | SCHIZOPHRENIA | PATHWAY ANALYSIS | GENE SET ANALYSIS | IDENTIFICATION | EXPRESSION | HERITABILITY | GENOME-WIDE ASSOCIATION | INTERACTOME | Genes | Genomics | Methods
Journal Article
Bioinformatics (Oxford, England), ISSN 1367-4803, 05/2019
Genome-wide multi-omics profiling of complex diseases provides valuable resources and opportunities to discover associations between various measures of genes... 
Journal Article
Cell Reports, ISSN 2211-1247, 01/2019, Volume 26, Issue 2, pp. 496 - 506.e3
We systematically investigated the landscape of tumor-suppressor gene (TSG) inactivation events in 33 cancer types by quantitatively measuring their global and... 
RB1 | two-hit model | CDKN2A | cell cycle pathway | transcriptome impact | tumor suppressor gene | The Cancer Genome Atlas | ACTIVATION | VARIANTS | DECAY | LANDSCAPE | GENOME-WIDE ANALYSIS | MUTATIONS | EXPRESSION | TSGENE | CELL BIOLOGY
Journal Article
Briefings in Bioinformatics, ISSN 1467-5463, 05/2018, Volume 19, Issue 3, pp. 450 - 460
Assessing the impact of kinase in gene fusion is essential for both identifying driver fusion genes (FGs) and developing molecular targeted therapies. Kinase... 
Precision medicine | Kinase domain retention | Gene fusion network | Kinase | Gene fusion | Protein-Tyrosine Kinases - genetics | Neoplasms - genetics | Receptor Protein-Tyrosine Kinases - genetics | Oncogene Fusion | Oncogene Proteins, Fusion - genetics | Humans | Protein Domains | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 04/2012, Volume 72, Issue 8 Supplement, pp. LB-96 - LB-96
Journal Article
Frontiers in Genetics, ISSN 1664-8021, 04/2019, Volume 10
Crohn’s Disease (CD) is one of the predominant forms of inflammatory bowel disease (IBD). A combination of genetic and non-genetic risk factors have been... 
Crohn’s Disease | TWAS | COP9 signalosome | GWAS | eQTL | integrative study
Journal Article
PLoS Computational Biology, ISSN 1553-734X, 02/2014, Volume 10, Issue 2
  A major challenge in interpreting the large volume of mutation data identified by next-generation sequencing (NGS) is to distinguish driver mutations from... 
Proteins | Ontology | Genes | Melanoma | Genomes | Tumorigenesis | Mutation | Cancer
Journal Article
Bioinformatics (Oxford, England), ISSN 1367-4803, 03/2019
Diseases and traits are under dynamic tissue-specific regulation. However, heterogeneous tissues are often collected in biomedical studies, which reduce the... 
Journal Article