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1. Full Text Serum MicroRNA Signatures Identified in a Genome-Wide Serum MicroRNA Expression Profiling Predict Survival of Non–Small-Cell Lung Cancer
by Zhibin Hu and Xi Chen and Yang Zhao and Tian Tian and Guangfu Jin and Yongqian Shu and Yijiang Chen and Lin Xu and Ke Zen and Chenyu Zhang and Hongbing Shen
Journal of Clinical Oncology, ISSN 0732-183X, 04/2010, Volume 28, Issue 10, pp. 1721 - 1726
Purpose Recent findings that human serum contains stably expressed microRNA (miRNA) have revealed a great potential of serum miRNA signature as disease... 
ADJUVANT CHEMOTHERAPY | BIOMARKERS | MECHANISM | GENE | BIOGENESIS | ONCOLOGY | PROGNOSIS | BRONCHIOALVEOLAR STEM-CELLS | ADENOCARCINOMA | CLASSIFICATION | SUPPRESSION | Lung Neoplasms - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Lung Neoplasms - mortality | Carcinoma, Squamous Cell - genetics | Humans | Middle Aged | Gene Expression Profiling - methods | Male | Risk | Carcinoma, Non-Small-Cell Lung - mortality | Female | Adenocarcinoma - genetics | MicroRNAs - blood
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2. Full Text Plasma miRNAs as early biomarkers for detecting hepatocellular carcinoma
by Wen, Yang and Han, Jing and Chen, Jianguo and Dong, Jing and Xia, Yongxiang and Liu, Jibin and Jiang, Yue and Dai, Juncheng and Lu, Jianhua and Jin, Guangfu and Han, Jiali and Wei, Qingyi and Shen, Hongbing and Sun, Beicheng and Hu, Zhibin
International Journal of Cancer, ISSN 0020-7136, 10/2015, Volume 137, Issue 7, pp. 1679 - 1690
The early detection of hepatocellular carcinoma (HCC) presents a challenge because of the lack of specific biomarkers. Serum/plasma microRNAs (miRNAs) can... 
miRNA | early detection | plasma | biomarker | hepatocellular carcinoma | Plasma | Hepatocellular carcinoma | Biomarker | Early detection | MiRNA | CIRCULATING MICRORNAS | POPULATION | DIAGNOSIS | CELLS | NONINVASIVE BIOMARKERS | CANCER | ADHESION | ONCOLOGY | TARGETS | SERUM MICRORNAS | MICRORNA EXPRESSION | Liver Neoplasms - genetics | Carcinoma, Hepatocellular - diagnosis | Humans | Male | Biomarkers, Tumor - blood | Liver Neoplasms - blood | Liver Neoplasms - diagnosis | Carcinoma, Hepatocellular - genetics | Carcinoma, Hepatocellular - pathology | Adult | Female | Liver Neoplasms - pathology | Biomarkers, Tumor - genetics | MicroRNAs - blood | MicroRNAs - genetics | Carcinoma, Hepatocellular - blood | Neoplasm Staging | Early Diagnosis | Liver cancer | MicroRNA | Analysis | Liver | Hepatoma | Diagnosis | Biological markers | Liver cirrhosis | Cancer | Biomarkers
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3. Full Text Genetic variants of miRNA sequences and non-small cell lung cancer survival
by Hu, ZB and Chen, JP and Tian, T and Zhou, XY and Gu, HY and Xu, L and Zeng, Y and Miao, RF and Jin, GF and Ma, HX and Chen, YJ and Shen, HB
JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 07/2008, Volume 118, Issue 7, pp. 2600 - 2608
Recent evidence indicates that small noncoding RNA molecules known as microRNAs (miRNAs) can function as tumor suppressors and oncogenes. Mutation,... 
BREAST-CANCER | MEDICINE, RESEARCH & EXPERIMENTAL | PROGNOSIS | RNAS | IDENTIFICATION | MICRORNA | PREDICTION | Prognosis | Cricetulus | Humans | Middle Aged | Lung Neoplasms - pathology | Male | MicroRNAs - metabolism | RNA, Messenger - metabolism | Transfection | Aged, 80 and over | Adult | Female | RNA Precursors - metabolism | Microfilament Proteins - genetics | CHO Cells | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Cell Line | Cricetinae | Carcinoma, Non-Small-Cell Lung - genetics | RNA, Messenger - genetics | Kaplan-Meier Estimate | Genotype | RNA Precursors - genetics | Lung Neoplasms - therapy | Reverse Transcriptase Polymerase Chain Reaction | Animals | Cell Line, Tumor | Aged | MicroRNAs - genetics | Polymorphism, Single Nucleotide | Neoplasm Staging | Lung cancer, Small cell | Development and progression | MicroRNA | Lung cancer, Non-small cell | Index Medicus | Abridged Index Medicus
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4. Full Text The association between telomere length and cancer risk in population studies
by Zhu, Xun and Han, Wei and Xue, Wenjie and Zou, Yuxia and Xie, Cuiwei and Du, Jiangbo and Jin, Guangfu
Scientific Reports, ISSN 2045-2322, 02/2016, Volume 6, Issue 1, p. 22243
Telomeres are crucial in the maintenance of chromosome integrity and genomic stability. A series of epidemiological studies have examined the association... 
PERIPHERAL-BLOOD LEUKOCYTES | LUNG-CANCER | CIGARETTE-SMOKING | HEPATOCELLULAR-CARCINOMA | MULTIDISCIPLINARY SCIENCES | PANCREATIC-CANCER | PROSTATE-CANCER | SQUAMOUS-CELL CARCINOMA | SHANGHAI WOMENS HEALTH | CHROMOSOME ENDS | CHINESE POPULATION | Telomere Shortening | Gastrointestinal Neoplasms - genetics | Risk Assessment | Humans | Risk Factors | Head and Neck Neoplasms - genetics | Telomere Homeostasis | Telomere - genetics | Literature reviews | Telomeres | Yeast | Head and neck cancer | Population studies | Head & neck cancer | Telomerase | Risk factors | Tumors | Cancer
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5. Full Text A Functional Genetic Variant in microRNA-196a2 Is Associated with Increased Susceptibility of Lung Cancer in Chinese
by Tian Tian and Yongqian Shu and Jiaping Chen and Zhibin Hu and Lin Xu and Guangfu Jin and Jie Liang and Ping Liu and Xiaoyi Zhou and Ruifen Miao and Hongxia Ma and Yijiang Chen and Hongbing Shen
Cancer Epidemiology Biomarkers & Prevention, ISSN 1055-9965, 04/2009, Volume 18, Issue 4, pp. 1183 - 1187
microRNAs (miRNA) are a new class of non-protein-coding, small RNAs that function as tumor suppressors or oncogenes. They participate in diverse biological... 
lung cancer | molecular epidemiology | microRNA | polymorphism | Lung Neoplasms - genetics | Genetic Predisposition to Disease | Carcinoma, Squamous Cell - genetics | Humans | Middle Aged | Risk Factors | Genotype | Lung Neoplasms - pathology | Male | Small Cell Lung Carcinoma - genetics | Adenocarcinoma - secondary | Case-Control Studies | Small Cell Lung Carcinoma - secondary | Genetic Variation | Homozygote | Asian Continental Ancestry Group | Polymorphism, Single Nucleotide - genetics | Carcinoma, Squamous Cell - secondary | Female | Adenocarcinoma - genetics | MicroRNAs - genetics | Neoplasm Staging | Smoking
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6. Full Text 太阳能光伏发电技术研究与应用
by 金正吉
现代企业文化, ISSN 1674-1145, 2017, Issue 24, pp. 216 - 216
随着现代工程产业的不断发展,带来的环境污染与能源危机也日益突出,太阳能作为一种新型的能源,其相关的太阳能光伏发电技术是当下很多国家重视和着重发展的一项科学技术.本文从太阳能光伏发电技术研究出发,分析了几种太阳能光伏发电技术的应用方式,供从事太阳能光伏发电技术研究与应用的工作人员参考. 
太阳能光伏发电 | 技术研究 | 应用
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7. Full Text Abstract 238: Interaction analysis between germline susceptibility loci and somatic alterations in lung cancer
by Wang, Yuzhuo and Wang, Cheng and Zhu, Meng and Jin, Guangfu and Shen, Hongbing
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 238 - 238
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8. Full Text Commentary: Post-GWAS era: What can we do beyond cancer genetic association studies?
by Wang, Cheng and Jin, Guangfu and Hu, Zhibin
International Journal of Epidemiology, ISSN 0300-5771, 02/2016, Volume 45, Issue 1, pp. 221 - 222
Genetic Predisposition to Disease | Genome-Wide Association Study | Polymorphism, Single Nucleotide | Genetic Association Studies | Neoplasms - genetics | Humans
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9. Full Text A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese
by Hu, Zhibin and Wu, Chen and Shi, Yongyong and Guo, Huan and Zhao, Xueying and Yin, Zhihua and Yang, Lei and Dai, Juncheng and Hu, Lingmin and Tan, Wen and Li, Zhiqiang and Deng, Qifei and Wang, Jiucun and Wu, Wei and Jin, Guangfu and Jiang, Yue and Yu, Dianke and Zhou, Guoquan and Chen, Hongyan and Guan, Peng and Chen, Yijiang and Shu, Yongqian and Xu, Lin and Liu, Xiangyang and Liu, Li and Xu, Ping and Han, Baohui and Bai, Chunxue and Zhao, Yuxia and Zhang, Haibo and Yan, Ying and Ma, Hongxia and Chen, Jiaping and Chu, Mingjie and Lu, Feng and Zhang, Zhengdong and Chen, Feng and Wang, Xinru and Jin, Li and Lu, Jiachun and Zhou, Baosen and Lu, Daru and Wu, Tangchun and Lin, Dongxin and Shen, Hongbing
Nature Genetics, ISSN 1061-4036, 08/2011, Volume 43, Issue 8, pp. 792 - 796
Lung cancer is the leading cause of cancer-related deaths worldwide. To identify genetic factors that modify the risk of lung cancer in individuals of Chinese... 
CELLS | IMPACT | MAPS | INFLAMMATION | 5P15.33 | STAT3 | GENETICS & HEREDITY | RISK | POPULATIONS | 15Q25 | VARIANT | Lung Neoplasms - genetics | Chromosomes, Human, Pair 13 - genetics | Genome-Wide Association Study | Lung - pathology | Carcinoma, Squamous Cell - genetics | Humans | Asian Continental Ancestry Group - genetics | Genotype | Small Cell Lung Carcinoma - genetics | Genetic Loci | Case-Control Studies | Chromosomes, Human, Pair 22 - genetics | Polymorphism, Single Nucleotide - genetics | Adenocarcinoma - genetics | Lung - metabolism | Genome, Human | Disease susceptibility | Genetic aspects | Genomes | Research | Single nucleotide polymorphisms | Lung cancer | Principal components analysis | Chromosomes | Validation studies
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10. Cancer risk prediction in post-genome-wide association study era
by Jin, Guangfu and Shen, Hongbing
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, ISSN 0254-6450, 10/2015, Volume 36, Issue 10, pp. 1045 - 1046
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11. Cancer risk prediction in post-genome-wide association study era
by Jin, Guangfu and Shen, Hongbing
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, ISSN 0254-6450, 10/2015, Volume 36, Issue 10, p. 1045
Genome-Wide Association Study | Neoplasms - genetics | Humans | Risk
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12. Full Text Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations
by Wu, Tangchun and Miao, Xiaoping and Qiao, Yan and Liu, Zhihua and Jin, Guangfu and Fu, Jianhua and Hu, Zhibin and Zhai, Kan and Zeng, Yixin and Ke, Yang and Liu, Yu and Liu, Zhe and Zhou, Yifeng and Jia, Weihua and Chang, Jiang and Wang, Feng and Lin, Dongxin and He, Zhonghu and Yu, Dianke and Zhan, Qimin and Shen, Yuanyuan and Tan, Wen and Shen, Hongbing and Guo, Chuanhai and Wu, Chen
Nature Genetics, ISSN 1061-4036, 07/2011, Volume 43, Issue 7, pp. 679 - 684
Esophageal squamous-cell carcinoma (ESCC) is one of the most prevalent cancers worldwide and occurs at a relatively high frequency in China. To identify... 
POLYMORPHISMS | GASTRIC-CANCER | GENETICS & HEREDITY | PLCE1 | RISK | GENETIC-VARIANTS | LINES | GAIN | RUNX1 | Genetic Predisposition to Disease | Genome-Wide Association Study | Prognosis | Carcinoma, Squamous Cell - epidemiology | Carcinoma, Squamous Cell - genetics | Humans | Middle Aged | Risk Factors | Asian Continental Ancestry Group - genetics | Male | China - epidemiology | Genetic Loci | Chromosomes, Human, Pair 21 - genetics | Case-Control Studies | Chromosomes, Human, Pair 6 - genetics | Esophageal Neoplasms - epidemiology | Esophageal Neoplasms - genetics | Polymorphism, Single Nucleotide - genetics | Female | Chromosomes, Human, Pair 5 - genetics | Squamous cell carcinoma | Genetic susceptibility | Development and progression | Genetic aspects | Research | Esophageal cancer | Risk factors | Studies | Sample size | Research & development--R&D | Genetics | Principal components analysis | Genomes | Chromosomes
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13. Full Text A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1
by Shi, Yongyong and Hu, Zhibin and Wu, Chen and Dai, Juncheng and Li, Huizhang and Dong, Jing and Wang, Meilin and Miao, Xiaoping and Zhou, Yifeng and Lu, Feng and Zhang, Hanze and Hu, Lingmin and Jiang, Yue and Li, Zhiqiang and Chu, Minjie and Ma, Hongxia and Chen, Jiaping and Jin, Guangfu and Tan, Wen and Wu, Tangchun and Zhang, Zhengdong and Lin, Dongxin and Shen, Hongbing
Nature Genetics, ISSN 1061-4036, 12/2011, Volume 43, Issue 12, pp. 1215 - 1218
Gastric cancer, including the cardia and non-cardia types, is the second leading cause of cancer-related deaths worldwide. To identify genetic risk variants... 
GENETIC-VARIATION | PSCA | ADENOCARCINOMAS | GENETICS & HEREDITY | SQUAMOUS-CELL CARCINOMA | PLCE1 | RISK | 10Q23 | ESOPHAGEAL | CHINESE POPULATION | STRATIFICATION | Receptors, Prostaglandin E, EP4 Subtype - genetics | Stomach Neoplasms - genetics | Genome-Wide Association Study | Humans | Middle Aged | Male | Genetic Loci | Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Case-Control Studies | Adult | Female | Aged | Polymorphism, Single Nucleotide | Odds Ratio | AMP-Activated Protein Kinases - genetics | Chromosomes, Human, Pair 3 - genetics | Chromosomes, Human, Pair 5 - genetics | Development and progression | Genetic aspects | Disease susceptibility | Research | Single nucleotide polymorphisms | Stomach cancer | Risk factors | Studies | Health care | Confidence intervals | Sample size | Pathogenesis | Research & development--R&D | Genomes | Manuscripts | Public health | Cancer
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14. Full Text Genetic variants of miRNA sequences and non-small cell lung cancer survival
by Hu, Zhibin and Chen, Jiaping and Tian, Tian and Zhou, Xiaoyi and Gu, Haiyong and Xu, Lin and Zeng, Yi and Miao, Ruifen and Jin, Guangfu and Ma, Hongxia and Chen, Yijiang and Shen, Hongbing
Journal of Clinical Investigation, ISSN 0021-9738, 07/2008, Volume 118, Issue 7, pp. 2600 - 2608
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15. Full Text Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions
by Wu, Chen and Kraft, Peter and Zhai, Kan and Chang, Jiang and Wang, Zhaoming and Li, Yun and Hu, Zhibin and He, Zhonghu and Jia, Weihua and Abnet, Christian C and Liang, Liming and Hu, Nan and Miao, Xiaoping and Zhou, Yifeng and Liu, Zhihua and Zhan, Qimin and Liu, Yu and Qiao, Yan and Zhou, Yuling and Jin, Guangfu and Guo, Chuanhai and Lu, Changdong and Yang, Haijun and Fu, Jianhua and Yu, Dianke and Freedman, Neal D and Ding, Ti and Tan, Wen and Goldstein, Alisa M and Wu, Tangchun and Shen, Hongbing and Ke, Yang and Zeng, Yixin and Chanock, Stephen J and Taylor, Philip R and Lin, Dongxin
Nature Genetics, ISSN 1061-4036, 10/2012, Volume 44, Issue 10, pp. 1090 - 1097
We conducted a genome-wide association study (GWAS) and a genome-wide gene-environment interaction analysis of esophageal squamous-cell carcinoma (ESCC) in... 
COLON-CANCER | HEPATOCELLULAR-CARCINOMA | RISK-FACTORS | MESSENGER-RNA | MOUSE MODEL | GROWTH | GENETICS & HEREDITY | ALCOHOL-DRINKING | GASTRIC CANCERS | BETA-CATENIN | EXPRESSION | Esophageal Neoplasms - etiology | Genetic Predisposition to Disease | Genome-Wide Association Study | Aldehyde Dehydrogenase, Mitochondrial | Carcinoma, Squamous Cell - genetics | Humans | Middle Aged | Risk Factors | Aldehyde Dehydrogenase - genetics | Male | Genetic Loci | Alcohol Drinking - adverse effects | Gene-Environment Interaction | Case-Control Studies | Asian Continental Ancestry Group | Carcinoma, Squamous Cell - etiology | Esophageal Neoplasms - genetics | Alcohol Dehydrogenase - genetics | Alleles | Adult | Female | Aged | Polymorphism, Single Nucleotide | Squamous cell carcinoma | Genetic susceptibility | Environmental aspects | Physiological aspects | Genetic aspects | Research | Esophageal cancer | Risk factors | Studies | Genetics | Genomes | Gene loci | Epidemiology | Manuscripts | Recruitment
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16. Full Text Genome-wide association studies identified loci contribute to phenotypic variance of gastric cancer
by Yan, Caiwang and Zhu, Meng and Huang, Tongtong and Yu, Fei and Jin, Guangfu
Gut, ISSN 0017-5749, 07/2018, Volume 67, Issue 7, pp. 1366 - 1368
We read with great interest the article by Mocellin et al,1 who conducted a comprehensive meta-analysis that nominated 11 germline variants at nine loci... 
cancer genetics | gastric cancer | genetic polymorphisms | cancer epidemiology | GASTROENTEROLOGY & HEPATOLOGY | RISK | Studies | Health care | Cardiovascular disease | Genomes | Higher education | Stomach cancer
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17. Full Text Gastric cancer may share genetic predisposition with esophageal squamous cell carcinoma in Chinese populations
by Yao, Linhua and Yu, Fei and Mao, Yingying and Wang, Tianpei and Qi, Qi and Ding, Hui and Wang, Jinchen and Ma, Hongxia and Dai, Juncheng and Zhang, Guoxin and Jin, Guangfu
Journal of Human Genetics, ISSN 1434-5161, 11/2018, Volume 63, Issue 11, pp. 1159 - 1168
Many features are shared between esophageal cancer (EC) and gastric cancer (GC). This study aimed to explore whether known EC susceptibility loci are also... 
RISK-FACTORS | ALDH2 | VARIANTS | ADH1B | ADENOCARCINOMA | PROSTATE-CANCER | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | ALCOHOL-CONSUMPTION | BARRETTS-ESOPHAGUS | GENOME-WIDE ASSOCIATION | Stomach Neoplasms - genetics | Genome-Wide Association Study | Adenocarcinoma - pathology | Prognosis | Follow-Up Studies | Carcinoma, Squamous Cell - epidemiology | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Asian Continental Ancestry Group - genetics | Stomach Neoplasms - pathology | China - epidemiology | Cyclic Nucleotide Phosphodiesterases, Type 4 - genetics | Aldehyde Dehydrogenase, Mitochondrial - genetics | Case-Control Studies | Esophageal Neoplasms - epidemiology | Esophageal Neoplasms - pathology | Esophageal Neoplasms - genetics | Phosphoinositide Phospholipase C - genetics | Stomach Neoplasms - epidemiology | Adenocarcinoma - genetics | Biomarkers, Tumor - genetics | Polymorphism, Single Nucleotide | Adenocarcinoma - epidemiology | Health risk assessment | Stomach cancer | Esophagus
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18. Full Text Genetic variants at 9p21.3 are associated with risk of esophageal squamous cell carcinoma in a Chinese population
by Lin, Xiaoming and Yan, Caiwang and Gao, Yong and Du, Jiangbo and Zhu, Xun and Yu, Fei and Huang, Tongtong and Dai, Juncheng and Ma, Hongxia and Jiang, Yue and Yin, Rong and Hu, Zhibin and Jin, Guangfu and Xu, Lin and Shen, Hongbing
Cancer Science, ISSN 1347-9032, 02/2017, Volume 108, Issue 2, pp. 250 - 255
Genome‐wide association studies have linked genetic variants at 9p21.3 to the risk of multiple cancers. However, the roles of genetic variants at 9p21.3 in... 
genetic variants | esophageal squamous cell carcinoma | susceptibility | 9p21.3 | gene expression | METAANALYSIS | GLIOMA | SUSCEPTIBILITY LOCI | P15(INK4B) | P16(INK4A) | 9p21 | CANCER | IDENTIFIES 3 | ONCOLOGY | SENESCENCE | LEUKEMIA | GENOME-WIDE ASSOCIATION | Confidence Intervals | Genome-Wide Association Study | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Humans | Risk Factors | Chromosomes, Human, Pair 9 | RNA, Messenger - metabolism | Cyclin-Dependent Kinase Inhibitor p18 - metabolism | Case-Control Studies | Genetic Variation | Asian Continental Ancestry Group | Cyclin-Dependent Kinase Inhibitor p18 - genetics | Esophageal Neoplasms - genetics | Cyclin-Dependent Kinase Inhibitor p15 - genetics | China | Esophageal Neoplasms - metabolism | Alleles | Cyclin-Dependent Kinase Inhibitor p15 - metabolism | Odds Ratio | Esophageal Squamous Cell Carcinoma | Squamous cell carcinoma | School facilities | RNA | Oncology, Experimental | Genomics | Genetic research | Disease susceptibility | Research | Gene expression | Esophageal cancer | Cancer | Education parks | Health care | Research & development--R&D | Leukemia | Melanoma | Alcohol | Population studies | Genomes | Breast cancer | Esophagus | Studies | Genetic variance |