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Nature Communications, ISSN 2041-1723, 06/2016, Volume 7, Issue 1, p. 11762
Age is a significant risk factor for the development of cancer. However, the mechanisms that drive age-related increases in cancer remain poorly understood. To... 
LIVER-CANCER | CRUCIAL ROLE | SECRETORY PHENOTYPE | CANCER-ASSOCIATED FIBROBLASTS | TUMOR SUPPRESSION | MULTIDISCIPLINARY SCIENCES | AGE-RELATED INCREASE | IN-VIVO | GENE-EXPRESSION | SUPPRESSOR-CELLS | CELLULAR SENESCENCE
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 10/2008, Volume 100, Issue 19, pp. 1380 - 1388
Journal Article
Cancer Research, ISSN 0008-5472, 07/2014, Volume 74, Issue 18, pp. 5057 - 5069
Cancer immunotherapy generally offers limited clinical benefit without coordinated strategies to mitigate the immunosuppressive nature of the tumor... 
ACTIVATION | INHIBITION | MICROENVIRONMENT | ONCOLOGY | ADENOCARCINOMA | INFLAMMATION | KINASE | CSF | POLARIZATION | IPILIMUMAB | PROGRESSION | Receptor, Macrophage Colony-Stimulating Factor - antagonists & inhibitors | Immunotherapy - methods | Receptor, Macrophage Colony-Stimulating Factor - immunology | Adenocarcinoma - pathology | Macrophage Colony-Stimulating Factor - biosynthesis | Mannose-Binding Lectins - biosynthesis | Tissue Array Analysis | Humans | Lectins, C-Type - immunology | Tumor Microenvironment | Deoxycytidine - pharmacology | Lectins, C-Type - biosynthesis | Female | Receptors, Cell Surface - biosynthesis | Carcinoma, Pancreatic Ductal - immunology | Macrophages - immunology | Signal Transduction | Macrophage Colony-Stimulating Factor - antagonists & inhibitors | Adenocarcinoma - immunology | Mice, Inbred C57BL | Pancreatic Neoplasms - pathology | Carcinoma, Pancreatic Ductal - therapy | Random Allocation | Carcinoma, Pancreatic Ductal - pathology | Receptors, Cell Surface - immunology | Macrophage Colony-Stimulating Factor - immunology | Animals | Mannose-Binding Lectins - immunology | Pancreatic Neoplasms - immunology | T-Lymphocytes - immunology | Mice | Deoxycytidine - analogs & derivatives | Cohort Studies | Pancreatic Neoplasms - therapy | macrophage | chemoresistance | pancreatic cancer | cytokines | innate immunity | immune checkpoint
Journal Article
American Journal of Surgical Pathology, ISSN 0147-5185, 09/2013, Volume 37, Issue 9, pp. 1349 - 1356
A relationship between human papillomavirus (HPV) infection and papillary squamous cell carcinoma (PSCC) has been suggested. However, to date, no studies have... 
Head and neck | RNA in situ hybridization | Human papillomavirus | Papillary squamous cell carcinoma | P16 | SURGERY | HUMAN-PAPILLOMAVIRUS TYPE-16 | IN-SITU HYBRIDIZATION | ORAL-CAVITY | UPPER AERODIGESTIVE TRACT | PREVALENCE | PATHOLOGY | CANCER | RISK HUMAN-PAPILLOMAVIRUS | HPV | papillary squamous cell carcinoma | p16 | E6/E7 | human papillomavirus | head and neck | EXPRESSION | Immunohistochemistry | Predictive Value of Tests | Head and Neck Neoplasms - virology | Carcinoma, Papillary - virology | Carcinoma, Squamous Cell - pathology | Carcinoma, Squamous Cell - virology | Humans | Middle Aged | RNA, Messenger - analysis | Male | Papillomaviridae - genetics | Papillomavirus Infections - diagnosis | Carcinoma, Squamous Cell - diagnosis | Papillomavirus Infections - pathology | Tumor Suppressor Protein p53 - analysis | Head and Neck Neoplasms - chemistry | Cyclin-Dependent Kinase Inhibitor p16 - analysis | In Situ Hybridization | Time Factors | Aged, 80 and over | Adult | Female | Oncogene Proteins, Viral - genetics | Papillomavirus Infections - virology | Carcinoma, Papillary - chemistry | Papillomavirus Infections - complications | Biomarkers, Tumor - analysis | Risk Factors | Kaplan-Meier Estimate | RNA, Viral - analysis | Carcinoma, Squamous Cell - chemistry | Papillomaviridae - isolation & purification | Papillomavirus Infections - mortality | Chi-Square Distribution | Carcinoma, Papillary - pathology | Head and Neck Neoplasms - pathology | Carcinoma, Papillary - mortality | Disease-Free Survival | Biopsy | Head and Neck Neoplasms - diagnosis | Aged | Head and Neck Neoplasms - mortality | Carcinoma, Papillary - diagnosis
Journal Article
Immunity, ISSN 1074-7613, 08/2017, Volume 47, Issue 2, pp. 323 - 338.e6
Journal Article
Nature, ISSN 0028-0836, 06/2012, Volume 486, Issue 7403, pp. 353 - 360
Journal Article
Journal Article
Journal Article
Journal of Statistical Software, ISSN 1548-7660, 2012, Volume 51, Issue 3, pp. 1 - 24
Medical researchers endeavor to identify potentially useful biomarkers to develop marker based screening assays for disease diagnosis and prevention. Useful... 
Three ordinal groups | Diagnostic test | Youden index | Volume under the ROC surface | DiagTest3Grp | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS | volume under the ROC surface | ROC CURVE | STATISTICS & PROBABILITY | AREAS | diagnostic test | three ordinal groups | OPERATING CHARACTERISTIC CURVES | ACCURACY
Journal Article
Cell Reports, ISSN 2211-1247, 09/2013, Volume 4, Issue 6, pp. 1116 - 1130
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 08/2017, Volume 23, Issue 15, pp. 4055 - 4065
Purpose: Cyclin-dependent kinase (CDK) 4/6 drives cell proliferation in estrogen receptor-positive (ER+) breast cancer. This single-arm phase II neoadjuvant... 
TRIAL | AROMATASE INHIBITOR | 1ST-LINE TREATMENT | RETINOBLASTOMA PROTEIN | ONCOLOGY | INTRINSIC SUBTYPE | IN-VIVO | DOUBLE-BLIND | LETROZOLE | CELL-PROLIFERATION | POSTMENOPAUSAL WOMEN | Cyclin-Dependent Kinase 6 - antagonists & inhibitors | Piperazines - administration & dosage | Breast Neoplasms - surgery | Triazoles - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Class I Phosphatidylinositol 3-Kinases - genetics | Receptor, ErbB-2 - genetics | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Nitriles - administration & dosage | Pyridines - adverse effects | Adult | Female | Neoadjuvant Therapy | Gene Expression Regulation, Neoplastic - drug effects | Cyclin-Dependent Kinase 4 - antagonists & inhibitors | Pyridines - administration & dosage | Breast Neoplasms - drug therapy | Piperazines - adverse effects | Disease-Free Survival | Breast Neoplasms - genetics | Estrogen Receptor alpha - genetics | Breast Neoplasms - pathology | Aged | Cell Proliferation - drug effects | Mutation | Neoplasm Staging | Cell proliferation | Anastrozole | Estrogens | Cyclin-dependent kinases | Estrogen | Estrogen receptors | Breast cancer | Kinases | Gene expression | Patients | ErbB-2 protein | Cyclin-dependent kinase 4 | Cyclin-dependent kinase | E2F protein | Inhibitors | Experimental design | Surgery | Cell cycle | Breast | Cancer | breast cancer | neoadjuvant | anastrozole | CDK4 | palbociclib
Journal Article