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American Journal of Ophthalmology, ISSN 0002-9394, 02/2019, Volume 198, pp. 223 - 261
To determine predictive factors and risk scores for conversion to overall advanced age-related macular degeneration (AMD), geographic atrophy (GA), neovascular... 
Macular degeneration | Studies | Proteins | Angiogenesis | Extracellular matrix | Genomes | Gene loci | Ophthalmology | Health risk assessment
Journal Article
JAMA Ophthalmology, ISSN 2168-6165, 07/2015, Volume 133, Issue 7, p. 785
  The complement factor H R1210C rare variant confers the strongest genetic risk for age-related macular degeneration and earlier age at onset; however, its... 
Macular degeneration | Genotype & phenotype | Genetics | Ophthalmology | Regression analysis
Journal Article
JAMA Ophthalmology, ISSN 2168-6165, 11/2016, Volume 134, Issue 11, p. 1272
  Importance: Age-related macular degeneration (AMD) is a multifactorial disease with genetic and environmental factors contributing to risk. Histopathologic... 
Macular degeneration | Histopathology | Microscopy | Aging | Genetics | Risk
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2010, Volume 107, Issue 16, pp. 7395 - 7400
Journal Article
Epidemiology, ISSN 1044-3983, 11/2012, Volume 23, Issue 6, pp. 912 - 913
Journal Article
by Wei Chen and Dwight Stambolian and Albert O. Edwards and Kari E. Branham and Mohammad Othman and Johanna Jakobsdottir and Nirubol Tosakulwong and Margaret A. Pericak-Vance and Peter A. Campochiaro and Michael L. Klein and Perciliz L. Tan and Yvette P. Conley and Atsuhiro Kanda and Laura Kopplin and Yanming Li and Katherine J. Augustaitis and Athanasios J. Karoukis and William K. Scott and Anita Agarwal and Jaclyn L. Kovach and Stephen G. Schwartz and Eric A. Postel and Matthew Brooks and Keith H. Baratz and William L. Brown and Complications of Age-Related Macular Degeneration Prevention Trial (CAPT) Research Group and Alexander J. Brucker and Anton Orlin and Gary Brown and Allen Ho and Carl Regillo and Larry Donoso and Lifeng Tian and Brian Kaderli and Dexter Hadley and Stephanie A. Hagstrom and Neal S. Peachey and Ronald Klein and Barbara E. K. Klein and Norimoto Gotoh and Kenji Yamashiro and Frederick Ferris and Jesen A. Fagerness and Robyn Reynolds and Lindsay A. Farrer and Ivana K. Kim and Joan W. Miller and Marta Cortón and Angel Carracedo and Manuel Sanchez-Salorio and Elizabeth W. Pugh and Kimberly F. Doheny and Maria Brion and Margaret M. DeAngelis and Daniel E. Weeks and Donald J. Zack and Emily Y. Chew and John R. Heckenlively and Nagahisa Yoshimura and Sudha K. Iyengar and Peter J. Francis and Nicholas Katsanis and Johanna M. Seddon and Jonathan L. Haines and Michael B. Gorin and Gonçalo R. Abecasis and Anand Swaroop and Mark T. Keating and Complications Age-Related Macular and Complications of Age-Related Macular Degeneration Prevention Trial Research Group and Complications of Age-Related Macular Degeneration Prevention Trial (CAPT) Research Group
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2010, Volume 107, Issue 16, pp. 7401 - 7406
Journal Article
Nature Genetics, ISSN 1061-4036, 10/2007, Volume 39, Issue 10, pp. 1200 - 1201
The association of variants in complement factors H and B with age-related macular degeneration has led to more intense genetic and functional analysis of the... 
FACTOR-H POLYMORPHISM | CFH | Y402H | VARIANT | GENES | GENETICS & HEREDITY | Genetic Variation | Macular Degeneration - genetics | Complement C3 - genetics | Humans | Risk Factors | Case-Control Studies | Macular degeneration | Genetic variation | Physiological aspects | Genetic aspects | Research | Complement (Immunology) | Risk factors | Aging | Genetics | Index Medicus
Journal Article
JAMA Ophthalmology, ISSN 2168-6165, 04/2013, Volume 131, Issue 4, p. 448
  Risk score models predicting the progression of age-related macular degeneration (AMD) to its advanced forms may be useful for targeting high-risk... 
Macular degeneration | Clinical trials | Ophthalmology | Risk factors | Validation studies | Genetic algorithms
Journal Article
by Fritsche, Lars G and Chen, Wei and Schu, Matthew and Yaspan, Brian L and Yu, Yi and Thorleifsson, Gudmar and Zack, Donald J and Arakawa, Satoshi and Cipriani, Valentina and Ripke, Stephan and Igo, Robert P and Buitendijk, Gabriëlle H. S and Sim, Xueling and Weeks, Daniel E and Guymer, Robyn H and Merriam, Joanna E and Francis, Peter J and Hannum, Gregory and Agarwal, Anita and Armbrecht, Ana Maria and Audo, Isabelle and Aung, Tin and Barile, Gaetano R and Benchaboune, Mustapha and Bird, Alan C and Bishop, Paul N and Branham, Kari E and Brooks, Matthew and Brucker, Alexander J and Cade, William H and Cain, Melinda S and Campochiaro, Peter A and Chan, Chi-Chao and Cheng, Ching-Yu and Chew, Emily Y and Chin, Kimberly A and Chowers, Itay and Clayton, David G and Cojocaru, Radu and Conley, Yvette P and Cornes, Belinda K and Daly, Mark J and Dhillon, Baljean and Edwards, Albert O and Evangelou, Evangelos and Fagerness, Jesen and Ferreyra, Henry A and Friedman, James S and Geirsdottir, Asbjorg and George, Ronnie J and Gieger, Christian and Gupta, Neel and Hagstrom, Stephanie A and Harding, Simon P and Haritoglou, Christos and Heckenlively, John R and Holz, Frank G and Hughes, Guy and Ioannidis, John P. A and Ishibashi, Tatsuro and Joseph, Peronne and Jun, Gyungah and Kamatani, Yoichiro and Katsanis, Nicholas and N Keilhauer, Claudia and Khan, Jane C and Kim, Ivana K and Kiyohara, Yutaka and Klein, Barbara E. K and Klein, Ronald and Kovach, Jaclyn L and Kozak, Igor and Lee, Clara J and Lee, Kristine E and Lichtner, Peter and Lotery, Andrew J and Meitinger, Thomas and Mitchell, Paul and Mohand-Saïd, Saddek and Moore, Anthony T and Morgan, Denise J and Morrison, Margaux A and Myers, Chelsea E and Naj, Adam C and Nakamura, Yusuke and Okada, Yukinori and Orlin, Anton and Ortube, M Carolina and Othman, Mohammad I and Pappas, Chris and Park, Kyu Hyung and Pauer, Gayle J. T and Peachey, Neal S and Poch, Olivier and Priya, Rinki Ratna and Reynolds, Robyn and Richardson, Andrea J and Ripp, Raymond and Rudolph, Guenther and Ryu, Euijung and ... and AMD Gene Consortium and The AMD Gene Consortium
Nature Genetics, ISSN 1061-4036, 04/2013, Volume 45, Issue 4, pp. 433 - 439
Journal Article