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Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1865 - 6
The use of oncolytic viruses (OVs) for cancer treatment is emerging as a successful strategy that combines the direct, targeted killing of the cancer with the... 
IMMUNE-RESPONSE | VIRUS | STRATEGY | MULTIDISCIPLINARY SCIENCES | BLOCKADE | COMBINATION | CELL-DEATH | Stomatitis | Animal models | Immune response | Immune checkpoint | Oncolysis | Herpes simplex | Viruses | Breast cancer | Tumors | Metastases
Journal Article
PLoS Pathogens, ISSN 1553-7366, 08/2018, Volume 14, Issue 8, pp. e1007264 - e1007264
Herpes Simplex Virus 1 (HSV1) is amongst the most clinically advanced oncolytic virus platforms. However, efficient and sustained viral replication within... 
RAPAMYCIN | IMMUNE-RESPONSE | MESSENGER-RNA TRANSLATION | MYXOMA-VIRUS | ACTIVATION | ONCOLYTIC VIROTHERAPY | MICROBIOLOGY | VIRAL REPLICATION | HERPES-SIMPLEX-VIRUS | INTERFERON | VIROLOGY | MIQE GUIDELINES | PARASITOLOGY | Physiological aspects | Genetic aspects | Research | Genetic regulation | Herpes simplex virus | Cancer cells | TOR protein | Transplants & implants | Funding | Xenotransplantation | Herpes simplex | Viruses | Genomes | mRNA | Infections | Biochemistry | Kinases | Proteins | Immunology | Repressors | Transformed cells | Immunotherapy | Xenografts | Oncolysis | Inhibition | Research centers | Supervision | Medical research | Protein biosynthesis | Rapamycin | Pharmacology | Children & youth | Infectious diseases | Inhibitors | Protein synthesis | Herpes viruses | Replication | Initiation factor eIF-4E | Tumors | Cancer | Index Medicus | TOR Serine-Threonine Kinases/antagonists & inhibitiors | Herpes Simplex/genetics | Herpes Simplex/pathology | Neoplasms/pathology | Eukaryotic Initiation Factor-4E/genetics | Humans | Cercopithecus aethiops | Ubiquitin-Protein Ligases/deficiency | Immediate-Early Proteins/genetics | Neoplasms/genetics | Herpes Simplex/complications | Life Sciences | Eukaryotic Initiation Factor-4E/metabolism | HEK293 Cells | Neoplasms/complications | Organisms, Genetically Modified | Herpesvirus 1, Human/genetics | Vero Cells | Catalytic Domain/drug effects | Signal Transduction/genetics | Cells, Cultured | Adaptator Proteins, Signal Transducing/genetics | Gene Expression Regulation, Neoplastic/drug effects | Phosphoproteins/genetics | Adaptator Proteins, Signal Transducing/metabolism | Animals | Immediate-Early Proteins/deficiency | Mice | Phosphoproteins/metabolims | TOR Serine-Threonine Kinases/chemistry | Protein Kinase Inhibitors/pharmacology | Herpesvirus 1, Human/drug effects | Ubiquitin-Protein Ligases/genetics | Neoplasms/virology
Journal Article
Molecular Therapy - Oncolytics, ISSN 2372-7705, 02/2016, Volume 3, pp. 16001 - 16001
Oncolytic viruses are known to stimulate the antitumor immune response by specifically replicating in tumor cells. This is believed to be an important aspect... 
MEDICINE, RESEARCH & EXPERIMENTAL | DEFECTS | GENE | MICROENVIRONMENT | ONCOLOGY | IFN-GAMMA | TRANSCRIPTION | MARKERS | CENTRAL-NERVOUS-SYSTEM | IDENTIFICATION | CANCER | RENAL-CELL CARCINOMA
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2018, Volume 20, Issue suppl_6, pp. vi101 - vi101
Abstract Biological effects of AC electric fields at frequencies between 100–300 kHz discovered a decade ago are being applied to cancer cells as a therapeutic... 
Journal Article
PLoS Genetics, ISSN 1553-7390, 09/2015, Volume 11, Issue 9
  Schmid metaphyseal chondrodysplasia (MCDS) involves dwarfism and growth plate cartilage hypertrophic zone expansion resulting from dominant mutations in the... 
Musculoskeletal diseases | Physiological aspects | Cartilage cells | Health aspects | Endoplasmic reticulum | Transcription factors | Ontology | Genomes | Kinases | Gene expression | Dwarfism | Pathology | Protein folding | Collagen | Extracellular matrix | Software | Mutation | Sensors
Journal Article
Molecular Therapy - Oncolytics, ISSN 2372-7705, 2016, Volume 3, Issue C, p. 16001
Oncolytic viruses are known to stimulate the antitumor immune response by specifically replicating in tumor cells. This is believed to be an important aspect... 
Journal Article
PLoS Genetics, ISSN 1553-7390, 09/2015, Volume 11, Issue 9
  Schmid metaphyseal chondrodysplasia (MCDS) involves dwarfism and growth plate cartilage hypertrophic zone expansion resulting from dominant mutations in the... 
Transcription factors | Ontology | Genomes | Kinases | Gene expression | Dwarfism | Pathology | Protein folding | Collagen | Extracellular matrix | Software | Mutation | Sensors | Endoplasmic reticulum
Journal Article
Molecular Therapy. Oncolytics, 02/2016, Volume 3, p. 16001
  Oncolytic viruses are known to stimulate the antitumor immune response by specifically replicating in tumor cells. This is believed to be an important aspect... 
Journal Article
Journal Article