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Genes, Chromosomes and Cancer, ISSN 1045-2257, 12/2019, Volume 58, Issue 12, pp. 859 - 874
Acute myeloid leukemia (AML) is a complex disease characterized by a diverse range of recurrent molecular aberrations that occur in many different... 
acute myeloid leukemia | transcription factors | epigenetics | transcriptional networks | Epigenetic inheritance | Analysis | Genomics | Hematopoietic stem cells | Translocation | Networks | Deregulation | Myeloid leukemia | Leukemia | Genomes | Perturbation | Cell differentiation | Hemopoiesis | Complexity | Stem cells | Disruption | Mutation | Acute myeloid leukemia
Journal Article
PLoS Genetics, ISSN 1553-7390, 07/2013, Volume 9, Issue 7
  Hypomethylating agents reactivate tumor suppressor genes that are epigenetically silenced in cancer. Inevitably these genes are resilenced, leading to drug... 
Enzymes | DNA methylation | Epigenetics | Kinases | Drug resistance | Gene expression | Experiments | Cancer therapies | Deoxyribonucleic acid--DNA | Cancer
Journal Article
ISSN 1066-5099, 06/2012, Volume 30, Issue 6, p. 1053
  The basic helix-loop-helix (bHLH) proteins are a large family of transcription factors that regulate the formation and fate of tissue stem cells. In... 
Genes | Stem cells | Genomes | Deoxyribonucleic acid--DNA
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 218 - 17
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2007, Volume 104, Issue 45, pp. 17692 - 17697
Conservation of the vertebrate body plan has been attributed to the evolutionary stability of gene-regulatory networks (GRNs). We describe a regulatory circuit... 
Transgenic animals | Hematopoiesis | Blood cells | Stem cells | Cell lines | Transgenes | Embryos | Blood | Endothelial cells | Hematopoietic stem cells | Hemangioblast | Hematopoietic stem cell | Transcription factor network | Network motif | BMP | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTIONAL NETWORK | hematopoietic stem cell | ADULT | STEM-CELL ENHANCER | EMBRYONIC BLOOD | hematopoiesis | EVOLUTION | transcription factor network | ENDOTHELIAL-CELLS | MICE | DIFFERENTIATION | hemangioblast | EXPRESSION | network motif | Proto-Oncogene Proteins - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Proto-Oncogene Protein c-fli-1 - genetics | Gene Expression Regulation | Proto-Oncogene Proteins - genetics | Proto-Oncogene Proteins - chemistry | GATA2 Transcription Factor - chemistry | Blood Vessels - embryology | Embryo, Mammalian - physiology | Animals | Basic Helix-Loop-Helix Transcription Factors - metabolism | Enhancer Elements, Genetic | Proto-Oncogene Protein c-fli-1 - metabolism | GATA2 Transcription Factor - metabolism | Hematopoietic Stem Cells - physiology | Proto-Oncogene Protein c-fli-1 - chemistry | Hematopoiesis - physiology | Mice | Blood Vessels - physiology | Binding Sites | GATA2 Transcription Factor - genetics | T-Cell Acute Lymphocytic Leukemia Protein 1 | Basic Helix-Loop-Helix Transcription Factors - chemistry | Genetic aspects | Hematopoietic system | DNA binding proteins | Properties | Biological Sciences
Journal Article
International Journal of Cancer, ISSN 0020-7136, 02/2016, Volume 138, Issue 3, pp. 525 - 532
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2016, Volume 113, Issue 16, pp. E2306 - E2315
Journal Article
Journal Article
Cell Reports, ISSN 2211-1247, 07/2017, Volume 20, Issue 3, pp. 572 - 585
Journal Article