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Annual Review of Physiology, ISSN 0066-4278, 01/2010, Volume 72, p. 273
  The gastric parietal cell was the first system where a regulated membrane recycling hypothesis was proposed as the principal means for moving molecular... 
Proteins | Enzymes | Signal transduction | Membranes | Physiology | Cells | Adenosine triphosphatase
Journal Article
American Journal of Physiology, ISSN 0363-6143, 12/2012, Volume 303, Issue 12, p. C1301
  In primary culture, the gastric parietal cell's deeply invaginated apical membrane, seen in microscopy by phalloidin binding to F-actin (concentrated in... 
Proteins | Cell culture | Membranes | Microscopy | Morphology | Physiology
Journal Article
American Journal of Physiology, ISSN 0363-6143, 08/2010, Volume 299, Issue 2, p. C413
  Ezrin is an important membrane/actin cytoskeleton linker protein, especially in epithelia. Ezrin has two important binding domains: an NH...-terminal region... 
Proteins | Plasma | Phosphorylation | Membranes | Cellular biology | Cytoskeleton | Physiology | Mutation | Gene expression
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2008, Volume 105, Issue 46, pp. 17955 - 17960
Journal Article
Journal of Cell Science, ISSN 0021-9533, 1999, Volume 112, Issue 16, pp. 2639 - 2646
Cultured rabbit parietal cells were used to evaluate morphological responses to activators and inhibitors of HCl secretion. Immunofluorescence was used to... 
H,K-ATPase | Membrane traffic | Membrane recycling hypothesis | Signalling | Acid secretion | Ezrin | PRIMARY CULTURE | ULTRASTRUCTURAL-CHANGES | HCL SECRETION | ezrin | GLUCOSE-TRANSPORT | RECYCLING HYPOTHESIS | COMPARTMENT | membrane traffic | PLASMA-MEMBRANE | CELL BIOLOGY | membrane recycling hypothesis | acid secretion | EPITHELIAL-CELLS | OXYNTIC CELLS | GASTRIC-ACID SECRETION | signalling | Cytoskeletal Proteins | Hydrochloric Acid - metabolism | Actins - metabolism | Phosphoproteins - metabolism | Proton Pumps - metabolism | Cell Membrane - chemistry | Isoquinolines - pharmacology | Phosphoproteins - analysis | Actins - analysis | Thiocyanates - pharmacology | Anti-Ulcer Agents - pharmacology | Omeprazole - pharmacology | Cell Membrane - metabolism | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Receptors, Histamine H2 - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | Rabbits | H(+)-K(+)-Exchanging ATPase - metabolism | Proton Pump Inhibitors | Cells, Cultured | Enzyme Inhibitors - pharmacology | Imidazoles - pharmacology | Parietal Cells, Gastric - cytology | Parietal Cells, Gastric - enzymology | Animals | Sulfonamides | Vacuoles - metabolism | Signal Transduction - physiology | Biological Transport - physiology | Pyridines - pharmacology | Thiazoles - pharmacology | Enzyme Activation - physiology | Parietal Cells, Gastric - secretion
Journal Article
Journal of Gastroenterology, ISSN 0944-1174, 12/2013, Volume 48, Issue 12, pp. 1343 - 1352
Proton pump inhibitors (PPIs) are pro-drugs requiring an acidic pH for activation. The specificity of PPI toward the proton pump is mainly due to the extremely... 
Omeprazole | Medicine & Public Health | Pantoprazole | Colorectal Surgery | Hepatology | Gastroenterology | Abdominal Surgery | Surgical Oncology | Lansoprazole | CLOSTRIDIUM-DIFFICILE INFECTION | RISK-FACTORS | ACID-SUPPRESSING DRUGS | BACTERIAL GASTROENTERITIS | DUODENAL-ULCER | H-2-RECEPTOR ANTAGONISTS | GASTRIC-CANCER | REFLUX DISEASE | GASTROENTEROLOGY & HEPATOLOGY | PEPTIC-ULCER | Immunotherapy - methods | Proton Pump Inhibitors - pharmacology | Humans | Lysosomes - enzymology | Enzymes - drug effects | Male | Spleen - drug effects | 2-Pyridinylmethylsulfinylbenzimidazoles - pharmacology | Dose-Response Relationship, Drug | Proton Pump Inhibitors - administration & dosage | Spleen - enzymology | Anti-Ulcer Agents - pharmacology | Omeprazole - pharmacology | Enzymes - metabolism | Lansoprazole - administration & dosage | Lysosomes - drug effects | Cell Line | Prodrugs | Mice, Inbred C57BL | Omeprazole - administration & dosage | Anti-Ulcer Agents - administration & dosage | Animals | Immune System - drug effects | Lansoprazole - pharmacology | Cell Line, Tumor | Mice | Mice, Inbred BALB C | 2-Pyridinylmethylsulfinylbenzimidazoles - administration & dosage | Mass Spectrometry - methods | Hydrogen-Ion Concentration | Cysteine | Peptides | Immunotherapy | Proton pump inhibitors | Mass spectrometry | Cells | Cystine | Tumors
Journal Article
Journal Article
American Journal of Physiology, ISSN 0363-6143, 07/2008, Volume 295, Issue 1, p. C192
  In a comparison of three different tissues, the membrane cytoskeleton linker protein ezrin was found to assume high levels of phosphorylation on... 
Proteins | Tissue | Cellular biology | Digestive system | Comparative studies | Cytoskeleton | Biochemistry
Journal Article