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The EMBO Journal, ISSN 0261-4189, 10/2018, Volume 37, Issue 20, p. n/a
Lactate dehydrogenase A (LDHA) has appropriately received attention as a therapeutic target for the treatment of a broad spectrum of tumor types, yet little is... 
GLYCOLYSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | CELL BIOLOGY | Inhibitors | Acids | Therapeutic applications | Acid resistance | Melanoma | Amino acids | Lactate dehydrogenase | Lactic acid | Metabolism | L-Lactate dehydrogenase | Views | Cancer
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2007, Volume 104, Issue 49, pp. 19500 - 19505
Journal Article
2002, ISBN 9780911704556, ix, 364
Book
Journal of Clinical Investigation, ISSN 0021-9738, 01/2008, Volume 118, Issue 1, pp. 79 - 88
Despite great interest in cancer chemoprevention, effective agents are few. Here we show that chloroquine, a drug that activates the stress-responsive Atm-p53... 
MEDICINE, RESEARCH & EXPERIMENTAL | BCL-X-L | SIGNALING PATHWAYS | INDUCED APOPTOSIS | PHOSPHORYLATION | ATM | AUTOPHAGY | CYTOCHROME-C RELEASE | MYC-INDUCED LYMPHOMAGENESIS | TRANSGENIC MICE | P53 | Apoptosis - drug effects | Humans | Apoptosis - genetics | Male | Autophagy - drug effects | Burkitt Lymphoma - pathology | Neoplasms, Experimental - pathology | Chloroquine - pharmacology | Cell Transformation, Neoplastic - genetics | Autophagy - genetics | B-Lymphocytes - pathology | B-Lymphocytes - metabolism | Protein-Serine-Threonine Kinases - metabolism | Fibroblasts - metabolism | Tumor Suppressor Proteins - metabolism | Embryo, Mammalian - pathology | Cell Cycle Proteins - metabolism | Neoplasms, Experimental - prevention & control | bcl-2-Associated X Protein - metabolism | Ataxia Telangiectasia Mutated Proteins | Fibroblasts - pathology | Ataxia Telangiectasia - pathology | Ataxia Telangiectasia - genetics | Mice | Proto-Oncogene Proteins c-myc - genetics | Neoplasms, Experimental - metabolism | bcl-2 Homologous Antagonist-Killer Protein - genetics | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Embryo, Mammalian - metabolism | Tumor Suppressor Protein p53 - genetics | DNA-Binding Proteins - metabolism | Caspases - metabolism | Lysosomes - metabolism | Burkitt Lymphoma - prevention & control | Mice, Mutant Strains | Tumor Suppressor Proteins - genetics | Neoplasms, Experimental - genetics | Burkitt Lymphoma - genetics | Cell Cycle Proteins - genetics | Female | Lysosomes - pathology | Antirheumatic Agents - pharmacology | bcl-2-Associated X Protein - genetics | Antirheumatic Agents - therapeutic use | Ataxia Telangiectasia - prevention & control | Caspases - genetics | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Tumor Suppressor Protein p53 - metabolism | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Burkitt Lymphoma - metabolism | Chloroquine - therapeutic use | Ataxia Telangiectasia - metabolism | DNA-Binding Proteins - genetics | Cell Transformation, Neoplastic - metabolism | Proto-Oncogene Proteins c-myc - metabolism | Animals | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Cell Transformation, Neoplastic - pathology | Prevention | Chloroquine | Lysosomes | Dosage and administration | Research | Drug therapy | Health aspects | Cancer
Journal Article
by Klionsky, Daniel J and Abeliovich, Hagai and Agostinis, Patrizia and Agrawal, Devendra K and Aliev, Gjumrakch and Askew, David S and Baba, Misuzu and Baehrecke, Eric H and Bahr, Ben A and Ballabio, Andrea and Bamber, Bruce A and Bassham, Diane C and Bergamini, Ettore and Bi, Xiaoning and Biard-Piechaczyk, Martine and Blum, Janice S and Bredesen, Dale E and Brodsky, Jeffrey L and Brumell, John H and Brunk, Ulf T and Bursch, Wilfried and Camougrand, Nadine and Cebollero, Eduardo and Cecconi, Francesco and Chen, Yingyu and Chin, Lih-Shen and Choi, Augustine and Chu, Charleen T and Chung, Jongkyeong and Clark, Robert S.B and Clarke, Peter G.H and Clarke, Steven G and Clave, Corinne and Cleveland, John L and Codogno, Patrice and Colombo, María Isabel and Coto-Montes, Ana and Cregg, James M and Cuervo, Ana Maria and Debnath, Jayanta and Dennis, Patrick B and Dennis, Phillip A and Demarchi, Francesca and Deretic, Vojo and Devenish, Rodney J and Di Sano, Federica and Dice, J. Fred and Distelhorst, Clark W and Dinesh-Kumar, Savithramma P and Eissa, N. Tony and DiFiglia, Marian and Djavaheri-Mergny, Mojgan and Dorsey, Frank C and Dröge, Wulf and Dron, Michel and Dunn, Jr, William A and Duszenko, Michael and Elazar, Zvulun and Esclatine, Audrey and Eskelinen, Eeva-Liisa and Fésüs, László and Finley, Kim D and Fuentes, José M and Fueyo-Margareto, Juan and Fujisaki, Kozo and Galliot, Brigitte and Gao, Fen-Biao and Gewirtz, David A and Gibson, Spencer B and Gohla, Antje and Goldberg, Alfred L and Gonzalez, Ramon and González-Estévez, Cristina and Gorski, Sharon M and Gottlieb, Roberta A and Häussinger, Dieter and He, You-Wen and Heidenreich, Kim and Hill, Joseph A and Høyer-Hansen, Maria and Hu, Xun and Huang, Wei-Pang and Iwasaki, Akiko and Jäättelä, Marja and Jackson, William T and Jiang, Xuejun and Jin, Shengkan V and Johansen, Terje and Jung, Jae U and Kadowaki, Motoni and Kang, Chanhee and Kelekar, Ameeta and Kessel, David H and Kiel, Jan A.K.W and Kim, Hong Pyo and Kimchi, Adi and Kinsella, Timothy J and Kiselyov, Kirill and Kitamoto, Katsuhiko and Knecht, Erwin and ... and Geriatrik and Institutionen för medicin och hälsa and Farmakologi and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Hälsouniversitetet
Autophagy, ISSN 1554-8627, 02/2008, Volume 4, Issue 2, pp. 151 - 175
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 12/2014, Volume 6, Issue 12, pp. 1509 - 1511
MYC family oncoproteins (MYC, N‐MYC and L‐MYC) function as basic helix‐loop‐helix‐leucine zipper (bHLH‐Zip) transcription factors that are activated (i.e.,... 
Ubiquitin | Proteins | Transcription factors | Cell growth | Colorectal cancer | Stem cells | Cell cycle | Myc protein | Ubiquitin-protein ligase | Huwe1 protein | Leucine zipper proteins
Journal Article
Journal Article