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Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2016, Volume 59, Issue 14, pp. 6671 - 6689
Over the past decade, first and second generation EGFR inhibitors have significantly improved outcomes for lung cancer patients with activating mutations in... 
GROWTH-FACTOR RECEPTOR | IRREVERSIBLE INHIBITORS | IN-VITRO | GEFITINIB | CHEMISTRY, MEDICINAL | METHIONINE MUTANT | BIOLOGICAL EVALUATION | TYROSINE KINASE INHIBITOR | DRUG-RESISTANCE | MUTATIONS | THREONINE | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Rats, Wistar | Antineoplastic Agents - chemical synthesis | Humans | Molecular Conformation | Crystallography, X-Ray | Lung Neoplasms - pathology | Male | Structure-Activity Relationship | Benzimidazoles - chemistry | Nicotine - pharmacology | Dose-Response Relationship, Drug | Neoplasms, Experimental - pathology | Protein Kinase Inhibitors - chemistry | Receptor, Epidermal Growth Factor - metabolism | Antineoplastic Agents - pharmacology | Carcinoma, Non-Small-Cell Lung - pathology | Protein Kinase Inhibitors - chemical synthesis | Lung Neoplasms - enzymology | Benzimidazoles - chemical synthesis | Models, Molecular | Rats | Antineoplastic Agents - chemistry | Drug Discovery | Animals | Nicotine - chemical synthesis | Mice, Nude | Nicotine - analogs & derivatives | Nicotine - chemistry | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Benzimidazoles - pharmacology | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Protein Kinase Inhibitors - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Carcinoma, Non-Small-Cell Lung - enzymology | Mutation | Neoplasms, Experimental - drug therapy | Drug Screening Assays, Antitumor | Index Medicus
Journal Article
by Vos, Theo and Abajobir, Amanuel Alemu and Abate, Kalkidan Hassen and Abbafati, Cristiana and Abbas, Kaja M and Abd-Allah, Foad and Abdulkader, Rizwan Suliankatchi and Abdulle, Abdishakur M and Abebo, Teshome Abuka and Abera, Semaw Ferede and Aboyans, Victor and Abu-Raddad, Laith J and Ackerman, Ilana N and Adamu, Abdu Abdullahi and Adetokunboh, Olatunji and Afarideh, Mohsen and Afshin, Ashkan and Agarwal, Sanjay Kumar and Aggarwal, Rakesh and Agrawal, Anurag and Agrawal, Sutapa and Ahmadieh, Hamid and Ahmed, Muktar Beshir and Aichour, Ibtihel and Aichour, Amani Nidhal and Aichour, Miloud Taki Eddine and Aiyar, Sneha and Akinyemi, Rufus Olusola and Akseer, Nadia and Al Lami, Faris Hasan and Alahdab, Fares and Al-Aly, Ziyad and Alam, Khurshid and Alam, Noore and Alam, Tahiya and Alasfoor, Deena and Alene, Kefyalew Addis and Ali, Raghib and Alizadeh-Navaei, Reza and Alkerwi, Ala'a and Alla, François and Allebeck, Peter and Allen, Christine and Al-Maskari, Fatma and Al-Raddadi, Rajaa and Alsharif, Ubai and Alsowaidi, Shirina and Altirkawi, Khalid A and Amare, Azmeraw T and Amini, Erfan and Ammar, Walid and Amoako, Yaw Ampem and Andersen, Hjalte H and Antonio, Carl Abelardo T and Anwari, Palwasha and Ärnlöv, Johan and Artaman, Al and Aryal, Krishna Kumar and Asayesh, Hamid and Asgedom, Solomon W and Assadi, Reza and Atey, Tesfay Mehari and Atnafu, Niguse Tadele and Atre, Sachin R and Avila-Burgos, Leticia and Avokphako, Euripide Frinel G Arthur and Awasthi, Ashish and Bacha, Umar and Badawi, Alaa and Balakrishnan, Kalpana and Banerjee, Amitava and Bannick, Marlena S and Barac, Aleksandra and Barber, Ryan M and Barker-Collo, Suzanne L and Bärnighausen, Till and Barquera, Simon and Barregard, Lars and Barrero, Lope H and Basu, Sanjay and Battista, Bob and Battle, Katherine E and Baune, Bernhard T and Bazargan-Hejazi, Shahrzad and Beardsley, Justin and Bedi, Neeraj and Beghi, Ettore and Béjot, Yannick and Bekele, Bayu Begashaw and Bell, Michelle L and Bennett, Derrick A and Bensenor, Isabela M and Benson, Jennifer and Berhane, Adugnaw and Berhe, Derbew Fikadu and Bernabé, Eduardo and Betsu, Balem Demtsu and Beuran, Mircea and Beyene, Addisu Shunu and Bhala, Neeraj and ... and GBD 2016 Dis Injury Incidence Prev and GBD 2016 Disease and Injury Incidence and Prevalence Collaborators and Institutionen för hälsovetenskaper and Örebro universitet
The Lancet, ISSN 0140-6736, 09/2017, Volume 390, Issue 10100, pp. 1211 - 1259
As mortality rates decline, life expectancy increases, and populations age, non-fatal outcomes of diseases and injuries are becoming a larger component of the... 
MORTALITY | DEPRESSION | MEDICINE, GENERAL & INTERNAL | CHRONIC PAIN | CLIMATE-CHANGE | FUTURE | PERSONAL HEALTH-CARE | TRENDS | Medicine, Experimental | Medical research | Mental disorders | Disease | Personal health | Mortality | Mental health | Disease control | Risk factors | Studies | Disability | Aging | Age | Public health | Injury analysis | Injuries | Chronic illnesses | Guillain-Barre syndrome | Low back pain | Gout | Disorders | Mental depression | Tropical diseases | Incidence | Ratios | Fertility | Anxiety | Alzheimer's disease | Life expectancy | Population growth | Nutrient deficiency | Neurodegenerative diseases | Violence | Anemia | Regression analysis | Firearms | Self destructive behavior | Hearing loss | Diseases | Charities | Substance use | Hospitals | Tuberculosis | Adults | Cardiovascular diseases | Bayesian analysis | Headache | Populations | Iron | Sexual assault | Demographics | Pain | Remission | Children | Heart diseases | Complications | Aggression | Migraine | Diabetes mellitus | Health risks | Estimates | Life span | Community medicine, Social medicine: 801 | Samfunnsmedisin, sosialmedisin: 801 | Epidemiology medical and dental statistics: 803 | Epidemiologi medisinsk og odontologisk statistikk: 803 | VDP | Helsefag: 800 | Health sciences: 800 | Medisinske Fag: 700 | Medical disciplines: 700 | Global Health Metrics | Clinical Medicine | Allmänmedicin | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | General Practice
Journal Article
by Abbott, B. P and Abbott, R and Abbott, T. D and Acernese, F and Ackley, K and Adams, C and Phythian-Adams, A.T and Addesso, P and Adhikari, R. X and Adya, V. B and Affeldt, C and Afrough, M and Agarwal, B and Agathos, M and Agatsuma, K and Aggarwal, N.T and Aguiar, O. D and Aiello, L and Ain, A and Ajith, P and Allen, B and Allen, G and Allocca, A and Altin, P. A and Amato, A and Ananyeva, A and Anderson, S. B and Anderson, W. G and Antier, S and Appert, S and Arai, K and Araya, M. C and Areeda, J. S and Arnaud, N and Arun, K. G and Ascenzi, S and Ashton, G and Ast, M and Aston, S. M and Astone, P and Aufmuth, P and Aulbert, C and AultONeal, K and Avila-Alvarez, A and Babak, S and Bacon, P and Bader, M. K. M and Bae, S and Baker, P. T and Baldaccini, F and Ballardin, G and Ballmer, S. W and Banagiri, S and Barayoga, J. C and Barclay, S. E and Barish, B. C and Barker, R.D and Barone, F and Barr, B and Barsotti, L and Barsuglia, M and Barta, D and Bartlett, J and Bartos, I and Bassiri, R and Basti, A and Batch, J. C and Baune, C and Bawaj, M and Bazzan, M and Becsy, B and Beer, C and Bejger, M and Belahcene, I and Bell, A. S and Berger, B. K and Bergmann, G and Berry, C. P. L and Bersanetti, D and Bertolini, A and Betzwieser, J and Bhagwat, S and Bhandare, R and Bilenko, I. A and Billingsley, G and Billman, C. R and Birch, M.J and Birney, R and Birnholtz, O and Biscans, S and Bisht, A and Bitossi, M and Biwer, C and Bizouard, M. A and Blackburn, J. K and Blackman, J and Blair, C. D and Blair, D. G and Blair, R. M and Bloemen, S and ... and LIGO Sci Virgo Collaboration and LIGO Scientific and Virgo Collaboration
Physical Review Letters, ISSN 0031-9007, 06/2017, Volume 118, Issue 22, p. 221101
We describe the observation of GW170104, a gravitational-wave signal produced by the coalescence of a pair of stellar-mass black holes. The signal was measured... 
GW150914 | GALACTIC DISTRIBUTION | EVOLUTION | PARAMETER-ESTIMATION | PHYSICS, MULTIDISCIPLINARY | DYNAMICAL FORMATION | LIGO | MASS | MERGERS | COMPACT OBJECT FORMATION | GRAVITATIONAL-WAVE OBSERVATIONS | General Relativity and Quantum Cosmology | Physics | Astrophysics
Journal Article
Physical Review Letters, ISSN 0031-9007, 2016, Volume 116, Issue 6, p. 061102
On September 14, 2015 at 09: 50: 45 UTC the two detectors of the Laser Interferometer Gravitational-Wave Observatory simultaneously observed a transient... 
SYSTEM | PHYSICS, MULTIDISCIPLINARY | COALESCENCE | FIELD | LIGO | MASS | PULSAR | STELLAR | RADIATION | Intervals | Gravitational waves | Detectors | Waveforms | Luminosity | Texts | Black holes (astronomy) | Interferometers | General Relativity and Quantum Cosmology | Sciences of the Universe | Astrophysics | Cosmology and Extra-Galactic Astrophysics | Physics
Journal Article