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Genome Medicine, ISSN 1756-994X, 06/2015, Volume 7, Issue 1
Age-related macular degeneration (AMD) is a leading cause of blindness. Most vision loss occurs following the transition from a disease of deposit formation... 
RNA sequencing | Genes | Genomics | Inhibin | Biological products industry | Development and progression | Genomes | Inflammation | Gene expression | Macular degeneration | Cell death | Analysis | Stem cells | Blindness | Physiological aspects | Genetic research
Journal Article
PLoS ONE, ISSN 1932-6203, 2009, Volume 4, Issue 12, pp. e8152 - e8152
Transformation of somatic cells with a set of embryonic transcription factors produces cells with the pluripotent properties of embryonic stem cells (ESCs).... 
PROGENITOR CELLS | MACULAR TRANSLOCATION | RCS RAT | SUBRETINAL TRANSPLANTATION | VISUAL FUNCTION | RPE | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | AUTOLOGOUS TRANSPLANTATION | HUMAN FIBROBLASTS | PHOTORECEPTOR DEGENERATION | Biomarkers - metabolism | Epithelial Cells - transplantation | Immunohistochemistry | Cell Polarity | Photoreceptor Cells, Vertebrate - ultrastructure | Retinal Pigment Epithelium - transplantation | Cell Survival | Humans | Proto-Oncogene Proteins c-fos - metabolism | Retinal Diseases - therapy | Rats | Photoreceptor Cells, Vertebrate - cytology | Macrophages - cytology | Vision, Ocular - physiology | Animals | Retinal Pigment Epithelium - ultrastructure | Cell Shape | Retinal Diseases - pathology | Cell Differentiation | Epithelial Cells - cytology | Induced Pluripotent Stem Cells - cytology | Retinal Diseases - physiopathology | Phagocytosis | Retinal Pigment Epithelium - cytology | Macular degeneration | Epithelium | Embryonic stem cells | Health aspects | Monomolecular films | Transformation | Transcription factors | Pathogenesis | Embryo cells | Stem cell transplantation | Retina | Transplantation | Retinal pigment epithelium | Visual perception | Engineering | Allografts | Fibroblasts | Degeneration | Age | Medical personnel | Cell survival | Developmental biology | Medical treatment | Gene expression | Somatic cells | Stem cells | Photoreceptors | Pluripotency | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2005, Volume 102, Issue 20, pp. 7227 - 7232
Journal Article
Stem Cells, ISSN 1066-5099, 10/2009, Volume 27, Issue 10, pp. 2427 - 2434
Human induced pluripotent stem cells (iPSCs) have great promise for cellular therapy, but it is unclear if they have the same potential as human embryonic stem... 
Retinal pigmented epithelium | Age-related macular degeneration | Induced pluripotent stem cells | Retinitis pigmentosa | ISOMEROHYDROLASE | ROD OUTER SEGMENTS | PHAGOCYTOSIS | MACULAR DEGENERATION | retinal pigmented epithelium | IPS CELLS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | MICROSOMAL PROTEIN | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | retinitis pigmentosa | induced pluripotent stem cells | RPE CELLS | DIFFERENTIATION | HEMATOLOGY | age-related macular degeneration | EYE DEVELOPMENT | EXPRESSION | Retinal Pigment Epithelium - metabolism | Cell Proliferation | Homeodomain Proteins - metabolism | Humans | Nerve Tissue Proteins - analysis | Retinal Diseases - therapy | RNA, Messenger - analysis | Retinal Rod Photoreceptor Cells - metabolism | RNA, Messenger - metabolism | SOXB1 Transcription Factors - metabolism | SOXB1 Transcription Factors - pharmacology | Homeodomain Proteins - pharmacology | Cell Differentiation - physiology | Integrin alphaV - metabolism | Biomarkers - metabolism | Cell Line | Nanog Homeobox Protein | Pluripotent Stem Cells - cytology | Biomarkers - analysis | Octamer Transcription Factor-3 - pharmacology | Phagocytosis - physiology | Regeneration - physiology | Nerve Tissue Proteins - metabolism | Pluripotent Stem Cells - metabolism | Phenotype | Regeneration - drug effects | Cell Differentiation - drug effects | Octamer Transcription Factor-3 - metabolism | Pluripotent Stem Cells - drug effects | Retinal Rod Photoreceptor Cells - cytology | Cell Polarity - physiology | Brain Tissue Transplantation - methods | Retinal Pigment Epithelium - cytology | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 07/2011, Volume 108, Issue 28, pp. E279 - E287
Age-related macular degeneration (AMD) is a leading cause of visual dysfunction worldwide. Amyloid β (Aβ) peptides, Aβ1–40 (Aβ40) and Aβ1–42 (Aβ42), have been... 
DRUSEN FORMATION | COMPLEMENT FACTOR-H | TARGETED REPLACEMENT | DIETARY-FAT | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | APOLIPOPROTEIN-E GENE | MOUSE MODEL | BETA IMMUNIZATION | MICROARRAY ANALYSIS | TRANSGENIC MICE | Retinal Pigment Epithelium - metabolism | Vision, Low - prevention & control | Apolipoprotein E4 - genetics | Dose-Response Relationship, Immunologic | Humans | Male | Complement System Proteins - metabolism | Retinal Pigment Epithelium - pathology | Antibodies, Bispecific - administration & dosage | Immunotherapy | Peptide Fragments - immunology | Amyloid beta-Peptides - metabolism | Dietary Fats - administration & dosage | Female | Disease Models, Animal | Macular Degeneration - etiology | Vision, Low - physiopathology | Macular Degeneration - physiopathology | Mice, Transgenic | Mice, Knockout | Antibodies, Bispecific - therapeutic use | Amyloid beta-Peptides - antagonists & inhibitors | Animals | Macular Degeneration - therapy | Peptide Fragments - antagonists & inhibitors | Amyloid beta-Peptides - immunology | Mice | Mice, Inbred BALB C | Macular Degeneration - pathology | Macular degeneration | Retina | Rodents | Cells | Blindness | Animal models | Deposits | Neurodegenerative diseases | Preservation | Cognitive ability | Antibodies | beta -Amyloid | Visual perception | Diets | Apolipoprotein E | Vision | Amyloid | retinal pigment epithelium | Alzheimer's disease | Age | Plaques | Index Medicus | PNAS Plus | Biological Sciences
Journal Article
Journal Article
Ophthalmic Research, ISSN 0030-3747, 10/2012, Volume 48, Issue 4, pp. 212 - 212
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2011, Volume 108, Issue 28, pp. 11307 - 11308
Journal Article
Ophthalmic Research, ISSN 0030-3747, 10/2012, Volume 48, Issue 4, pp. I - IV
Journal Article
Journal of Tissue Engineering and Regenerative Medicine, ISSN 1932-6254, 08/2013, Volume 7, Issue 8, pp. 642 - 653
Journal Article