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Journal of the American Chemical Society, ISSN 0002-7863, 04/2012, Volume 134, Issue 14, pp. 6068 - 6071
Journal Article
Synlett, ISSN 0936-5214, 03/2018, Volume 29, Issue 4, pp. 399 - 400
Jeffrey N. Johnston is a 1992 graduate of Xavier University where he completed his B.S. Chemistry degree (Honors, summa cum laude ). With summer research... 
cluster | CHEMISTRY, ORGANIC
Journal Article
Chemical Science, ISSN 2041-6520, 2019, Volume 10, Issue 4, pp. 1138 - 1143
A stereocontrolled synthesis of β -amino amides is reported. Innovation is encapsulated by the first use of nitroalkenes to achieve double umpolung in... 
Journal Article
Chemical Science, ISSN 2041-6520, 01/2019, Volume 10, Issue 4, pp. 1138 - 1143
A stereocontrolled synthesis of β2,3-amino amides is reported. Innovation is encapsulated by the first use of nitroalkenes to achieve double umpolung in... 
Journal Article
ISSN 2041-6520, 1/2019, Volume 1, Issue 4, pp. 1138 - 1143
A stereocontrolled synthesis of β 2,3 -amino amides is reported. Innovation is encapsulated by the first use of nitroalkenes to achieve double umpolung in... 
Journal Article
Chemical Science, ISSN 2041-6520, 03/2017, Volume 8, Issue 4, pp. 3187 - 3191
The 1,3,4-oxadiazole is an aromatic heterocycle valued for its low-lipophilicity in drug development. Substituents at the 2- and/or 5-positions can modulate... 
Oxadiazoles | Synthesis | Amines | Reagents | Electronics | Amino acids | Hydrazides | Standards
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 05/2008, Volume 130, Issue 18, pp. 5866 - 5867
Journal Article
Chemical Science, ISSN 2041-6520, 2018, Volume 9, Issue 8, pp. 2336 - 2339
The discovery that a C-2-symmetric bis(AMidine) [BAM] catalyst promotes an anti- selective addition of asubstituted alpha-nitro esters to imines is described,... 
AZA-HENRY REACTION | SYN-ALPHA,BETA-DIAMINO ACIDS | CATALYSIS | PROGENITORS | COMPLEX | AMINO-ACIDS | GLYCINE SCHIFF-BASE | REACTIVITY | ASYMMETRIC MANNICH REACTIONS | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | Substitutes | Esters | Catalysis | Imines | Catalysts | Chemical synthesis
Journal Article
Chemical Science, ISSN 2041-6520, 04/2015, Volume 6, Issue 4, pp. 2590 - 2595
Peptides consisting of D-amino amides are highly represented among both biologically active natural products and non-natural small molecules used in... 
AZA-HENRY REACTION | ACID-DERIVATIVES | CATALYSIS | POTENT | ASYMMETRIC-SYNTHESIS | ARYL | INHIBITORS | CHEMISTRY, MULTIDISCIPLINARY | DISCOVERY | Availability | Synthesis (chemistry) | Synthesis | Peptides | Amino acids | Amides | Aldehydes | Aliphatic compounds
Journal Article
ISSN 2041-6520, 3/2017, Volume 8, Issue 4, pp. 3187 - 3191
The 1,3,4-oxadiazole is an aromatic heterocycle valued for its low-lipophilicity in drug development. Substituents at the 2- and/or 5-positions can modulate... 
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 02/2004, Volume 126, Issue 6, pp. 1612 - 1613
A mild protocol for the synthesis of cis-aziridines is described that employs a catalytic amount of Brønsted acid. Despite the potential for diazo compound... 
ELECTRON-TRANSFER | DIELS-ALDER REACTIONS | LEWIS-ACID | IMINES | ASYMMETRIC AZIRIDINATION | VAPOL | MEDIA | CHEMISTRY, MULTIDISCIPLINARY | Chemical synthesis
Journal Article
Chemical Science, ISSN 2041-6520, 01/2019, Volume 10, Issue 4, pp. 1138 - 1143
A stereocontrolled synthesis of β2,3-amino amides is reported. Innovation is encapsulated by the first use of nitroalkenes to achieve double umpolung in... 
Synthesis | Molybdenum oxides | Innovations | Amides | Selectivity | Enantiomers
Journal Article
Chemical Communications, ISSN 1359-7345, 2016, Volume 52, Issue 1, pp. 152 - 155
It has been over a half-century since Kornblum demonstrated the conversion of a primary nitroalkane to a carboxylic acid; addition of an amine results in... 
TRANSFORMATION | AZA-HENRY REACTION | NITROCOMPOUNDS | ALPHA,BETA-UNSATURATED KETONES | NITRO-COMPOUNDS | CONVERSION | AMIDE | ENANTIOSELECTIVE CONJUGATE ADDITION | CHEMISTRY | CHEMISTRY, MULTIDISCIPLINARY | MOLECULAR-OXYGEN | Synthesis (chemistry) | Amines | Halogenation | Amides | Formations | Terminals | Carboxylic acids | Conversion
Journal Article
Chemical Science, ISSN 2041-6520, 4/2017, Volume 8, Issue 4, pp. 3187 - 3191
An innovative new synthesis approach to disubstituted 1,3,4-oxadiazoles is described, inspired by Umpolung Amide Synthesis (UmAS). The 1,3,4-oxadiazole is an... 
Chemistry
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2016, Volume 113, Issue 52, p. 14893
  Macrocyclic small molecules are attractive tools in the development of sensors, new materials, and therapeutics. Within early-stage drug discovery, they are... 
Molecules | Peptides | Research & development--R&D | Natural products | Chemical synthesis
Journal Article
Organic Letters, ISSN 1523-7060, 07/2014, Volume 16, Issue 14, pp. 3804 - 3807
Journal Article
ISSN 2041-6520, 2/2018, Volume 9, Issue 8, pp. 2336 - 2339
The discovery that a C 2 -symmetric bis(AMidine) [BAM] catalyst promotes an anti -selective addition of α-substituted α-nitro esters to imines is described,... 
Journal Article
ISSN 1359-7345, 12/2015, Volume 52, Issue 1, pp. 152 - 155
It has been over a half-century since Kornblum demonstrated the conversion of a primary nitroalkane to a carboxylic acid; addition of an amine results in... 
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 02/2005, Volume 127, Issue 5, pp. 1354 - 1355
A straightforward synthesis of aziridines is reported from an electron-rich azide (alkyl or aryl azide), electron-deficient olefin, and triflic acid in cold... 
KETONES | CYCLOADDITION | INTRAMOLECULAR SCHMIDT REACTIONS | DECOMPOSITION | ION | CHEMISTRY, MULTIDISCIPLINARY | ALKYL AZIDES | Amino acids | Synthesis | Chemical properties | Research | Olefins | Organic compounds
Journal Article
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